Maupas-Schwalm F et al. |
The sphingomyelin/ceramide pathway is involved in ERK1/2 phosphorylation, cell proliferation, and uPAR overexpression induced by tissue-type plasminogen activator. |
2004 |
FASEB J. |
pmid:15231724
|
Fujita T et al. |
Delta-catenin/NPRAP (neural plakophilin-related armadillo repeat protein) interacts with and activates sphingosine kinase 1. |
2004 |
Biochem. J. |
pmid:15193146
|
Brinkmann V et al. |
FTY720: sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function. |
2004 |
Am. J. Transplant. |
pmid:15196057
|
Im DS et al. |
Enhancement of sphingosine 1-phosphate-induced phospholipase C activation during G(0)-G(1) transition in rat hepatocytes. |
2004 |
J. Pharmacol. Sci. |
pmid:15215654
|
Pandey S and Assmann SM |
The Arabidopsis putative G protein-coupled receptor GCR1 interacts with the G protein alpha subunit GPA1 and regulates abscisic acid signaling. |
2004 |
Plant Cell |
pmid:15155892
|
Taha TA et al. |
Sphingosine-1-phosphate receptors: receptor specificity versus functional redundancy. |
2004 |
Biochim. Biophys. Acta |
pmid:15158755
|
Duong CQ et al. |
Expression of the lysophospholipid receptor family and investigation of lysophospholipid-mediated responses in human macrophages. |
2004 |
Biochim. Biophys. Acta |
pmid:15158762
|
Zhou H and Murthy KS |
Distinctive G protein-dependent signaling in smooth muscle by sphingosine 1-phosphate receptors S1P1 and S1P2. |
2004 |
Am. J. Physiol., Cell Physiol. |
pmid:15075212
|
Usui S et al. |
Blood lipid mediator sphingosine 1-phosphate potently stimulates platelet-derived growth factor-A and -B chain expression through S1P1-Gi-Ras-MAPK-dependent induction of Kruppel-like factor 5. |
2004 |
J. Biol. Chem. |
pmid:14711826
|
Gräler MH and Goetzl EJ |
The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors. |
2004 |
FASEB J. |
pmid:14715694
|
Ohmori T et al. |
Platelet-derived sphingosine 1-phosphate induces contraction of coronary artery smooth muscle cells via S1P2. |
2004 |
J. Thromb. Haemost. |
pmid:14717991
|
Renkl A et al. |
Distinct effects of sphingosine-1-phosphate, lysophosphatidic acid and histamine in human and mouse dendritic cells. |
2004 |
Int. J. Mol. Med. |
pmid:14719124
|
Jin ZQ et al. |
Sphingosine kinase activation mediates ischemic preconditioning in murine heart. |
2004 |
Circulation |
pmid:15451787
|
Lee C et al. |
Attenuation of shock-induced acute lung injury by sphingosine kinase inhibition. |
2004 |
J Trauma |
pmid:15580017
|
Yatomi Y et al. |
Sphingosine 1-phosphate breakdown in platelets. |
2004 |
J. Biochem. |
pmid:15625319
|
Galaria II et al. |
Differential regulation of ERK1/2 and p38(MAPK) by components of the Rho signaling pathway during sphingosine-1-phosphate-induced smooth muscle cell migration. |
2004 |
J. Surg. Res. |
pmid:15555614
|
Shida D et al. |
Sphingosine 1-phosphate transactivates c-Met as well as epidermal growth factor receptor (EGFR) in human gastric cancer cells. |
2004 |
FEBS Lett. |
pmid:15556605
|
Allende ML et al. |
Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720. |
2004 |
J. Biol. Chem. |
pmid:15459201
|
Ozbay T et al. |
ACTH regulates steroidogenic gene expression and cortisol biosynthesis in the human adrenal cortex via sphingolipid metabolism. |
2004 |
Endocr. Res. |
pmid:15666826
|
Clemens JJ et al. |
Synthesis of benzimidazole based analogues of sphingosine-1-phosphate: discovery of potent, subtype-selective S1P4 receptor agonists. |
2004 |
Bioorg. Med. Chem. Lett. |
pmid:15341948
|
Gonzalez E et al. |
Small interfering RNA-mediated down-regulation of caveolin-1 differentially modulates signaling pathways in endothelial cells. |
2004 |
J. Biol. Chem. |
pmid:15292187
|
Lee H et al. |
Lysophospholipids increase ICAM-1 expression in HUVEC through a Gi- and NF-kappaB-dependent mechanism. |
2004 |
Am. J. Physiol., Cell Physiol. |
pmid:15294853
|
Roth Z and Hansen PJ |
Sphingosine 1-phosphate protects bovine oocytes from heat shock during maturation. |
2004 |
Biol. Reprod. |
pmid:15317688
|
Hemmings DG et al. |
Sphingosine 1-phosphate-induced vasoconstriction is elevated in mesenteric resistance arteries from aged female rats. |
2004 |
Br. J. Pharmacol. |
pmid:15326035
|
Waeber C et al. |
Vascular sphingosine-1-phosphate S1P1 and S1P3 receptors. |
2004 Jul-Aug |
Drug News Perspect. |
pmid:15334188
|
De Luca T et al. |
NAD+/NADH and/or CoQ/CoQH2 ratios from plasma membrane electron transport may determine ceramide and sphingosine-1-phosphate levels accompanying G1 arrest and apoptosis. |
2005 |
Biofactors |
pmid:16873929
|
Lindner K et al. |
Ceramide alters endothelial cell permeability by a nonapoptotic mechanism. |
2005 |
Br. J. Pharmacol. |
pmid:15735657
|
Ikeda M et al. |
Sphingolipid-to-glycerophospholipid conversion in SPL-null cells implies the existence of an alternative isozyme. |
2005 |
Biochem. Biophys. Res. Commun. |
pmid:15737611
|
Yabu T et al. |
Thalidomide-induced antiangiogenic action is mediated by ceramide through depletion of VEGF receptors, and is antagonized by sphingosine-1-phosphate. |
2005 |
Blood |
pmid:15741222
|
Kee TH et al. |
Sphingosine kinase signalling in immune cells. |
2005 |
Clin. Exp. Pharmacol. Physiol. |
pmid:15743396
|
Suomalainen L et al. |
Sphingosine-1-phosphate inhibits nuclear factor kappaB activation and germ cell apoptosis in the human testis independently of its receptors. |
2005 |
Am. J. Pathol. |
pmid:15743789
|
Pilorget A et al. |
Inhibition of angiogenic properties of brain endothelial cells by platelet-derived sphingosine-1-phosphate. |
2005 |
J. Cereb. Blood Flow Metab. |
pmid:15829917
|
Bolick DT et al. |
Sphingosine-1-phosphate prevents tumor necrosis factor-{alpha}-mediated monocyte adhesion to aortic endothelium in mice. |
2005 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:15761190
|
Blom T et al. |
Enhancement of intracellular sphingosine-1-phosphate production by inositol 1,4,5-trisphosphate-evoked calcium mobilisation in HEK-293 cells: endogenous sphingosine-1-phosphate as a modulator of the calcium response. |
2005 |
Cell. Signal. |
pmid:15763425
|
Saini HS et al. |
Novel role of sphingosine kinase 1 as a mediator of neurotrophin-3 action in oligodendrocyte progenitors. |
2005 |
J. Neurochem. |
pmid:16313513
|
Mizugishi K et al. |
Essential role for sphingosine kinases in neural and vascular development. |
2005 |
Mol. Cell. Biol. |
pmid:16314531
|
Shida D et al. |
Lysophospholipids transactivate HER2/neu (erbB-2) in human gastric cancer cells. |
2005 |
Biochem. Biophys. Res. Commun. |
pmid:15649431
|
Itagaki K et al. |
Lysophosphatidic acid triggers calcium entry through a non-store-operated pathway in human neutrophils. |
2005 |
J. Leukoc. Biol. |
pmid:15522918
|
McVerry BJ and Garcia JG |
In vitro and in vivo modulation of vascular barrier integrity by sphingosine 1-phosphate: mechanistic insights. |
2005 |
Cell. Signal. |
pmid:15494205
|
Waters CM et al. |
c-Src is involved in regulating signal transmission from PDGFbeta receptor-GPCR(s) complexes in mammalian cells. |
2005 |
Cell. Signal. |
pmid:15494217
|
Edsbagge J et al. |
Vascular function and sphingosine-1-phosphate regulate development of the dorsal pancreatic mesenchyme. |
2005 |
Development |
pmid:15689381
|
Jaillard C et al. |
Edg8/S1P5: an oligodendroglial receptor with dual function on process retraction and cell survival. |
2005 |
J. Neurosci. |
pmid:15703400
|
Geoffroy K et al. |
Glomerular proliferation during early stages of diabetic nephropathy is associated with local increase of sphingosine-1-phosphate levels. |
2005 |
FEBS Lett. |
pmid:15710421
|
Takashiro Y et al. |
Involvement of p38 MAP kinase-mediated cytochrome c release on sphingosine-1-phosphate (S1P)- and N-monomethyl-S1P-induced cell death of PC12 cells. |
2005 |
Biochem. Pharmacol. |
pmid:15907808
|
Halin C et al. |
The S1P-analog FTY720 differentially modulates T-cell homing via HEV: T-cell-expressed S1P1 amplifies integrin activation in peripheral lymph nodes but not in Peyer patches. |
2005 |
Blood |
pmid:15870184
|
Takeshita A et al. |
Sphingosine 1-phosphate acts as a signal molecule in ceramide signal transduction of TNF-alpha-induced activator protein-1 in osteoblastic cell line MC3T3-E1 cells. |
2005 |
J Oral Sci |
pmid:15881228
|
Yin Z and Watsky MA |
Chloride channel activity in human lung fibroblasts and myofibroblasts. |
2005 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:15681397
|
Sauer B et al. |
Sphingosine 1-phosphate is involved in cytoprotective actions of calcitriol in human fibroblasts and enhances the intracellular Bcl-2/Bax rheostat. |
2005 |
Pharmazie |
pmid:15881612
|
Ma Y et al. |
Sphingosine activates protein kinase A type II by a novel cAMP-independent mechanism. |
2005 |
J. Biol. Chem. |
pmid:15883165
|
Kim JW et al. |
Synthesis and evaluation of sphingoid analogs as inhibitors of sphingosine kinases. |
2005 |
Bioorg. Med. Chem. |
pmid:15848761
|