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Cell. Mol. Life Sci. |
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Sphingosine 1-phosphate as a regulator of osteoclast differentiation and osteoclast-osteoblast coupling. |
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EMBO J. |
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2006 |
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2006 |
J. Pharmacol. Exp. Ther. |
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Targeting sphingosine-1-phosphate: a novel avenue for cancer therapeutics. |
2006 |
Cancer Cell |
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Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages. |
2006 |
Cancer Cell |
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Sphingosine-1-phosphate acts via rho-associated kinase and nitric oxide to regulate human placental vascular tone. |
2006 |
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Glabridin suppresses intercellular adhesion molecule-1 expression in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells by blocking sphingosine kinase pathway: implications of Akt, extracellular signal-regulated kinase, and nuclear factor-kappaB/Rel signaling pathways. |
2006 |
Mol. Pharmacol. |
pmid:16354764
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Sphingosine 1-phosphate regulates cytoskeleton dynamics: implications in its biological response. |
2006 |
Biochim. Biophys. Acta |
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2006 |
Prostaglandins Other Lipid Mediat. |
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The functional PDGFbeta receptor-S1P1 receptor signaling complex is involved in regulating migration of mouse embryonic fibroblasts in response to platelet derived growth factor. |
2006 |
Prostaglandins Other Lipid Mediat. |
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2006 |
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2006 |
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Arch. Immunol. Ther. Exp. (Warsz.) |
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Effects of LPA and S1P on the nervous system and implications for their involvement in disease. |
2007 |
Curr Drug Targets |
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Immunology. The sources of a lipid conundrum. |
2007 |
Science |
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2007 |
Arterioscler. Thromb. Vasc. Biol. |
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Cytochemical alterations in the rat retina by LPS administration. |
2007 |
Neurochem. Res. |
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J. Cell. Physiol. |
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2007 |
J. Neurochem. |
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Sphingosine-1-phosphate and calcium signaling in cerebellar astrocytes and differentiated granule cells. |
2007 |
Neurochem. Res. |
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Huwiler A and Zangemeister-Wittke U |
Targeting the conversion of ceramide to sphingosine 1-phosphate as a novel strategy for cancer therapy. |
2007 |
Crit. Rev. Oncol. Hematol. |
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Oxidative stress-dependent sphingosine kinase-1 inhibition mediates monoamine oxidase A-associated cardiac cell apoptosis. |
2007 |
Circ. Res. |
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Edaravone mimics sphingosine-1-phosphate-induced endothelial barrier enhancement in human microvascular endothelial cells. |
2007 |
Am. J. Physiol., Cell Physiol. |
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The sphingosine-1-phosphate analogue FTY720 reduces atherosclerosis in apolipoprotein E-deficient mice. |
2007 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:17158351
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Cytoskeleton/stretch-activated ion channel interaction regulates myogenic differentiation of skeletal myoblasts. |
2007 |
J. Cell. Physiol. |
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2007 |
Free Radic. Biol. Med. |
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Migration of CD4 T cells and dendritic cells toward sphingosine 1-phosphate (S1P) is mediated by different receptor subtypes: S1P regulates the functions of murine mature dendritic cells via S1P receptor type 3. |
2007 |
J. Immunol. |
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The sphingosine 1-phosphate receptor S1P2 triggers hepatic wound healing. |
2007 |
FASEB J. |
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Sphingosine 1-phosphate S1P2 and S1P3 receptor-mediated Akt activation protects against in vivo myocardial ischemia-reperfusion injury. |
2007 |
Am. J. Physiol. Heart Circ. Physiol. |
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The suppressive effect of sphingosine 1-phosphate on monocyte-endothelium adhesion may be mediated by the rearrangement of the endothelial integrins alpha(5)beta(1) and alpha(v)beta(3). |
2007 |
J. Thromb. Haemost. |
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Activation of sphingosine-1-phosphate receptor S1P5 inhibits oligodendrocyte progenitor migration. |
2007 |
FASEB J. |
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Sphingosine-1-phosphate attenuates proteoglycan aggrecan expression via production of prostaglandin E2 from human articular chondrocytes. |
2007 |
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PPARalpha agonist induces the accumulation of ceramide in the heart of rats fed high-fat diet. |
2007 |
J. Physiol. Pharmacol. |
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Very early alloantigen-independent trafficking of lymphocytes during ischemic acute kidney injury. |
2007 |
Kidney Int. |
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HDL and its sphingosine-1-phosphate content in cardioprotection. |
2007 |
Heart Fail Rev |
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Membrane-type 1 matrix metalloproteinase stimulates cell migration through epidermal growth factor receptor transactivation. |
2007 |
Mol. Cancer Res. |
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HDL-like lipoproteins in cerebrospinal fluid affect neural cell activity through lipoprotein-associated sphingosine 1-phosphate. |
2007 |
Biochem. Biophys. Res. Commun. |
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Agonist-modulated regulation of AMP-activated protein kinase (AMPK) in endothelial cells. Evidence for an AMPK -> Rac1 -> Akt -> endothelial nitric-oxide synthase pathway. |
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J. Biol. Chem. |
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[Measurement of sphingosine 1-phosphate as a biomarker of atherosclerosis]. |
2007 |
Rinsho Byori |
pmid:17511266
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Pioglitazone induces de novo ceramide synthesis in the rat heart. |
2007 |
Prostaglandins Other Lipid Mediat. |
pmid:17259076
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Sphingosine 1-phosphate-mediated trafficking of pathogenic Th2 and mast cells for the control of food allergy. |
2007 |
J. Immunol. |
pmid:17641024
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Sphingosine 1-phosphate accelerates wound healing in diabetic mice. |
2007 |
J. Dermatol. Sci. |
pmid:17643267
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Sphingosine-1-phosphate stimulates aldosterone secretion through a mechanism involving the PI3K/PKB and MEK/ERK 1/2 pathways. |
2007 |
J. Lipid Res. |
pmid:17609523
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A sphingosine kinase 1 mutation sensitizes the myocardium to ischemia/reperfusion injury. |
2007 |
Cardiovasc. Res. |
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Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma (HNSCC): attenuation of C(18)-ceramide in HNSCC tumors correlates with lymphovascular invasion and nodal metastasis. |
2007 |
Cancer Lett. |
pmid:17619081
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Lin CI et al. |
Sphingosine 1-phosphate regulates inflammation-related genes in human endothelial cells through S1P1 and S1P3. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17331465
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Sphingosine-1-phosphate initiates rapid retraction of pseudopodia by localized RhoA activation. |
2007 |
Cell. Signal. |
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Lysophospholipid receptors in cell signaling. |
2007 |
Biochemistry Mosc. |
pmid:17367289
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Hydrogen peroxide induces S1P1 receptors and sensitizes vascular endothelial cells to sphingosine 1-phosphate, a platelet-derived lipid mediator. |
2007 |
Am. J. Physiol., Cell Physiol. |
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