Gennero I et al. |
Effect of sphingosine-1-phosphate and analogues of lysophosphatidic acid on mesangial cell proliferation. |
2000 |
Ann. N. Y. Acad. Sci. |
pmid:10818478
|
Alessenko AV |
The role of sphingomyelin cycle metabolites in transduction of signals of cell proliferation, differentiation and death. |
2000 |
Membr Cell Biol |
pmid:10779176
|
Miura Y et al. |
Rho-mediated phosphorylation of focal adhesion kinase and myosin light chain in human endothelial cells stimulated with sphingosine 1-phosphate, a bioactive lysophospholipid released from activated platelets. |
2000 |
J. Biochem. |
pmid:10788802
|
Im DS et al. |
Characterization of a novel sphingosine 1-phosphate receptor, Edg-8. |
2000 |
J. Biol. Chem. |
pmid:10799507
|
Nugent D and Xu Y |
Sphingosine-1-phosphate: characterization of its inhibition of platelet aggregation. |
2000 |
Platelets |
pmid:10938902
|
Young KW et al. |
Effect of dimethylsphingosine on muscarinic M(3) receptor signalling in SH-SY5Y cells. |
2000 |
Eur. J. Pharmacol. |
pmid:10940357
|
Bischoff A et al. |
Sphingosine-1-phosphate and sphingosylphosphorylcholine constrict renal and mesenteric microvessels in vitro. |
2000 |
Br. J. Pharmacol. |
pmid:10952677
|
Motohashi K et al. |
Identification of lysophospholipid receptors in human platelets: the relation of two agonists, lysophosphatidic acid and sphingosine 1-phosphate. |
2000 |
FEBS Lett. |
pmid:10692584
|
Sugiyama A et al. |
Sphingosine 1-phosphate induces sinus tachycardia and coronary vasoconstriction in the canine heart. |
2000 |
Cardiovasc. Res. |
pmid:10727660
|
Goetzl EJ et al. |
Lysophospholipid enhancement of human T cell sensitivity to diphtheria toxin by increased expression of heparin-binding epidermal growth factor. |
1999 May-Jun |
Proc. Assoc. Am. Physicians |
pmid:10354366
|
Gueguen G et al. |
Structure-activity analysis of the effects of lysophosphatidic acid on platelet aggregation. |
1999 |
Biochemistry |
pmid:10387090
|
Li S et al. |
Chemical synthesis of D-ribo-phytosphingosine-1-phosphate, a potential modulator of cellular processes. |
1999 |
J. Lipid Res. |
pmid:9869657
|
Huang JS et al. |
Ethanol potentiates the mitogenic effects of sphingosine 1-phosphate by a zinc- and calcium-dependent mechanism in fibroblasts. |
1999 |
Arch. Biochem. Biophys. |
pmid:10334873
|
Kozawa O et al. |
Sphingosine 1-phosphate regulates heat shock protein 27 induction by a p38 MAP kinase-dependent mechanism in aortic smooth muscle cells. |
1999 |
Exp. Cell Res. |
pmid:10413591
|
Augé N et al. |
Role of sphingosine 1-phosphate in the mitogenesis induced by oxidized low density lipoprotein in smooth muscle cells via activation of sphingomyelinase, ceramidase, and sphingosine kinase. |
1999 |
J. Biol. Chem. |
pmid:10419457
|
Igarashi Y |
[Recent development of sphingosin 1-phosphate studies as a second messenger or a second agonist in cell signaling]. |
1999 |
Tanpakushitsu Kakusan Koso |
pmid:10396983
|
Hisano N et al. |
Induction and suppression of endothelial cell apoptosis by sphingolipids: a possible in vitro model for cell-cell interactions between platelets and endothelial cells. |
1999 |
Blood |
pmid:10361127
|
Meacci E et al. |
Effect of Rho and ADP-ribosylation factor GTPases on phospholipase D activity in intact human adenocarcinoma A549 cells. |
1999 |
J. Biol. Chem. |
pmid:10373471
|
Tolan D et al. |
Assessment of the extracellular and intracellular actions of sphingosine 1-phosphate by using the p42/p44 mitogen-activated protein kinase cascade as a model. |
1999 |
Cell. Signal. |
pmid:10376808
|
Okamoto H et al. |
EDG3 is a functional receptor specific for sphingosine 1-phosphate and sphingosylphosphorylcholine with signaling characteristics distinct from EDG1 and AGR16. |
1999 |
Biochem. Biophys. Res. Commun. |
pmid:10381367
|
Edsall LC and Spiegel S |
Enzymatic measurement of sphingosine 1-phosphate. |
1999 |
Anal. Biochem. |
pmid:10405296
|
Rakhit S et al. |
Sphingosine 1-phosphate stimulation of the p42/p44 mitogen-activated protein kinase pathway in airway smooth muscle. Role of endothelial differentiation gene 1, c-Src tyrosine kinase and phosphoinositide 3-kinase. |
1999 |
Biochem. J. |
pmid:10051434
|
Spiegel S |
Sphingosine 1-phosphate: a prototype of a new class of second messengers. |
1999 |
J. Leukoc. Biol. |
pmid:10080537
|
Liu CH et al. |
Ligand-induced trafficking of the sphingosine-1-phosphate receptor EDG-1. |
1999 |
Mol. Biol. Cell |
pmid:10198065
|
Watanabe Y and Akaike T |
Possible involvement of caspase-like family in maintenance of cytoskeleton integrity. |
1999 |
J. Cell. Physiol. |
pmid:10082131
|
Shinpo K et al. |
Protective effects of the TNF-ceramide pathway against glutamate neurotoxicity on cultured mesencephalic neurons. |
1999 |
Brain Res. |
pmid:10082875
|
Wang F et al. |
Involvement of focal adhesion kinase in inhibition of motility of human breast cancer cells by sphingosine 1-phosphate. |
1999 |
Exp. Cell Res. |
pmid:10047444
|
Goetzl EJ et al. |
Dual mechanisms for lysophospholipid induction of proliferation of human breast carcinoma cells. |
1999 |
Cancer Res. |
pmid:10493533
|
Goetzl EJ et al. |
Distinctive expression and functions of the type 4 endothelial differentiation gene-encoded G protein-coupled receptor for lysophosphatidic acid in ovarian cancer. |
1999 |
Cancer Res. |
pmid:10537322
|
Lee OH et al. |
Sphingosine 1-phosphate induces angiogenesis: its angiogenic action and signaling mechanism in human umbilical vein endothelial cells. |
1999 |
Biochem. Biophys. Res. Commun. |
pmid:10544002
|
Olivera A et al. |
Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival. |
1999 |
J. Cell Biol. |
pmid:10545499
|
Meacci E et al. |
Receptor-mediated activation of phospholipase D by sphingosine 1-phosphate in skeletal muscle C2C12 cells. A role for protein kinase C. |
1999 |
FEBS Lett. |
pmid:10471775
|
Windh RT et al. |
Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218/Edg-5 to the G(i), G(q), and G(12) families of heterotrimeric G proteins. |
1999 |
J. Biol. Chem. |
pmid:10488065
|
Banno Y et al. |
Differential phospholipase D activation by bradykinin and sphingosine 1-phosphate in NIH 3T3 fibroblasts overexpressing gelsolin. |
1999 |
J. Biol. Chem. |
pmid:10488069
|
Kozawa O et al. |
Sphingosine 1-phosphate induces heat shock protein 27 via p38 mitogen-activated protein kinase activation in osteoblasts. |
1999 |
J. Bone Miner. Res. |
pmid:10491224
|
Cavallini L et al. |
Ganglioside GM1 protection from apoptosis of rat heart fibroblasts. |
1999 |
Arch. Biochem. Biophys. |
pmid:10510273
|
Xia P et al. |
High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway. A possible mechanism for protection against atherosclerosis by HDL. |
1999 |
J. Biol. Chem. |
pmid:10551885
|
Dygas A et al. |
Exogenous sphingosine 1-phosphate and sphingosylphosphorylcholine do not stimulate phospholipase D in C6 glioma cells. |
1999 |
Acta Biochim. Pol. |
pmid:10453985
|
Wójcik M and Barańska J |
Sphingosine, sphingosylphosphorylcholine and sphingosine 1-phosphate modulate phosphatidylserine homeostasis in glioma C6 cells. |
1999 |
Acta Biochim. Pol. |
pmid:10453988
|
Waeber C and Chiu ML |
In vitro autoradiographic visualization of guanosine-5'-O-(3-[35S]thio)triphosphate binding stimulated by sphingosine 1-phosphate and lysophosphatidic acid. |
1999 |
J. Neurochem. |
pmid:10461914
|
Hotchin NA et al. |
Differential activation of focal adhesion kinase, Rho and Rac by the ninth and tenth FIII domains of fibronectin. |
1999 |
J. Cell. Sci. |
pmid:10444388
|
Kon J et al. |
Comparison of intrinsic activities of the putative sphingosine 1-phosphate receptor subtypes to regulate several signaling pathways in their cDNA-transfected Chinese hamster ovary cells. |
1999 |
J. Biol. Chem. |
pmid:10446161
|
Ancellin N and Hla T |
Differential pharmacological properties and signal transduction of the sphingosine 1-phosphate receptors EDG-1, EDG-3, and EDG-5. |
1999 |
J. Biol. Chem. |
pmid:10383399
|
Dallalio G et al. |
Inhibition of human erythroid colony formation by ceramide. |
1999 |
Exp. Hematol. |
pmid:10390188
|
Hla T et al. |
Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger? |
1999 |
Biochem. Pharmacol. |
pmid:10423159
|
Prieschl EE et al. |
The balance between sphingosine and sphingosine-1-phosphate is decisive for mast cell activation after Fc epsilon receptor I triggering. |
1999 |
J. Exp. Med. |
pmid:10429665
|
Sato K et al. |
Activation of phospholipase C-Ca2+ system by sphingosine 1-phosphate in CHO cells transfected with Edg-3, a putative lipid receptor. |
1999 |
FEBS Lett. |
pmid:9928946
|
Hung WC et al. |
Activation of caspase-3-like proteases in apoptosis induced by sphingosine and other long-chain bases in Hep3B hepatoma cells. |
1999 |
Biochem. J. |
pmid:9931312
|
Moore AN et al. |
Sphingosine-1-phosphate induces apoptosis of cultured hippocampal neurons that requires protein phosphatases and activator protein-1 complexes. |
1999 |
Neuroscience |
pmid:10579204
|
Zhang G et al. |
Comparative analysis of three murine G-protein coupled receptors activated by sphingosine-1-phosphate. |
1999 |
Gene |
pmid:9931453
|
Moolenaar WH |
Bioactive lysophospholipids and their G protein-coupled receptors. |
1999 |
Exp. Cell Res. |
pmid:10579925
|
Yang L et al. |
Metabolism and functional effects of sphingolipids in blood cells. |
1999 |
Br. J. Haematol. |
pmid:10583213
|
Sato K et al. |
Possible involvement of cell surface receptors in sphingosine 1-phosphate-induced activation of extracellular signal-regulated kinase in C6 glioma cells. |
1999 |
Mol. Pharmacol. |
pmid:9882706
|
Lynch KR and Im DS |
Life on the edg. |
1999 |
Trends Pharmacol. Sci. |
pmid:10603487
|
Sato K et al. |
Sphingosine 1-phosphate induces expression of early growth response-1 and fibroblast growth factor-2 through mechanism involving extracellular signal-regulated kinase in astroglial cells. |
1999 |
Brain Res. Mol. Brain Res. |
pmid:10640689
|
Goetzl EJ et al. |
Lysophosphatidic acid and sphingosine 1-phosphate protection of T cells from apoptosis in association with suppression of Bax. |
1999 |
J. Immunol. |
pmid:9973477
|
English D et al. |
Induction of endothelial cell chemotaxis by sphingosine 1-phosphate and stabilization of endothelial monolayer barrier function by lysophosphatidic acid, potential mediators of hematopoietic angiogenesis. |
1999 |
J. Hematother. Stem Cell Res. |
pmid:10645770
|
Lee MJ et al. |
Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate. |
1999 |
Cell |
pmid:10555146
|
Guo J et al. |
Effects of sphingosine 1-phosphate on pacemaker activity in rabbit sino-atrial node cells. |
1999 |
Pflugers Arch. |
pmid:10555561
|
Hong G et al. |
Sphingosine-1-phosphate modulates growth and adhesion of ovarian cancer cells. |
1999 |
FEBS Lett. |
pmid:10556527
|
De Jonghe S et al. |
Structure-activity relationship of short-chain sphingoid bases as inhibitors of sphingosine kinase. |
1999 |
Bioorg. Med. Chem. Lett. |
pmid:10560747
|
Xia P et al. |
Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells. |
1999 |
J. Biol. Chem. |
pmid:10567432
|
Meyer zu Heringdorf D et al. |
Role of sphingosine kinase in Ca(2+) signalling by epidermal growth factor receptor. |
1999 |
FEBS Lett. |
pmid:10567700
|
Stewart CE et al. |
Increased tyrosine kinase activity but not calcium mobilization is required for ceramide-induced apoptosis. |
1999 |
Exp. Cell Res. |
pmid:10413587
|
Sabbadini RA et al. |
The role of sphingolipids in the control of skeletal muscle function: a review. |
1999 |
Ital J Neurol Sci |
pmid:10937863
|
Gottlieb D et al. |
The DPL1 gene is involved in mediating the response to nutrient deprivation in Saccharomyces cerevisiae. |
1999 |
Mol. Cell Biol. Res. Commun. |
pmid:10329480
|
Pyne S et al. |
Extracellular actions of sphingosine I-phosphate through endothelial differentiation gene products in mammalian cells: role in regulating proliferation and apoptosis. |
1999 |
Biochem. Soc. Trans. |
pmid:10917611
|
Goetzl EJ and An S |
A subfamily of G protein-coupled cellular receptors for lysophospholipids and lysosphingolipids. |
1999 |
Adv. Exp. Med. Biol. |
pmid:10667339
|
Carpio LC et al. |
Sphingolipids stimulate cell growth via MAP kinase activation in osteoblastic cells. |
1999 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:10670688
|
Wang F et al. |
Sphingosine-1-phosphate inhibits motility of human breast cancer cells independently of cell surface receptors. |
1999 |
Cancer Res. |
pmid:10626811
|
Wang F et al. |
Sphingosine 1-phosphate stimulates cell migration through a G(i)-coupled cell surface receptor. Potential involvement in angiogenesis. |
1999 |
J. Biol. Chem. |
pmid:10585401
|
Denisova NA et al. |
The role of glutathione, membrane sphingomyelin, and its metabolites in oxidative stress-induced calcium "dysregulation" in PC12 cells. |
1999 |
Free Radic. Biol. Med. |
pmid:10641723
|
Van Brocklyn JR et al. |
Sphingosine 1-phosphate-induced cell rounding and neurite retraction are mediated by the G protein-coupled receptor H218. |
1999 |
J. Biol. Chem. |
pmid:9988698
|
Yang L et al. |
Sphingosine 1-phosphate formation and intracellular Ca2+ mobilization in human platelets: evaluation with sphingosine kinase inhibitors. |
1999 |
J. Biochem. |
pmid:10393324
|
Alemany R et al. |
Formyl peptide receptor signaling in HL-60 cells through sphingosine kinase. |
1999 |
J. Biol. Chem. |
pmid:9933590
|
Zhang Q et al. |
Sphingosine 1-phosphate stimulates fibronectin matrix assembly through a Rho-dependent signal pathway. |
1999 |
Blood |
pmid:10216094
|
Kleuser B et al. |
1Alpha,25-dihydroxyvitamin D3 inhibits programmed cell death in HL-60 cells by activation of sphingosine kinase. |
1998 |
Cancer Res. |
pmid:9581819
|
Qiao L et al. |
Synthesis and evaluation of a photolyzable derivative of sphingosine 1-phosphate--caged SPP. |
1998 |
Bioorg. Med. Chem. Lett. |
pmid:9871527
|
Sato K et al. |
Downregulation of mRNA expression of Edg-3, a putative sphingosine 1-phosphate receptor coupled to Ca2+ signaling, during differentiation of HL-60 leukemia cells. |
1998 |
Biochem. Biophys. Res. Commun. |
pmid:9878524
|
Hida H et al. |
Ceramide inhibits inwardly rectifying K+ currents via a Ras- and Raf-1-dependent pathway in cultured oligodendrocytes. |
1998 |
J. Neurosci. |
pmid:9786978
|
Vasta V et al. |
Effects of sphingosine 1-phosphate and bradykinin on phospholipid signalling in human epithelial A549 cells. |
1998 |
Biochem. Soc. Trans. |
pmid:9765948
|
Edsall LC et al. |
N,N-Dimethylsphingosine is a potent competitive inhibitor of sphingosine kinase but not of protein kinase C: modulation of cellular levels of sphingosine 1-phosphate and ceramide. |
1998 |
Biochemistry |
pmid:9737868
|
Spiegel S et al. |
Sphingosine-1-phosphate in cell growth and cell death. |
1998 |
Ann. N. Y. Acad. Sci. |
pmid:9668339
|
Igarashi Y |
Sphingosine-1-phosphate as an intercellular signaling molecule. |
1998 |
Ann. N. Y. Acad. Sci. |
pmid:9668340
|
Orlati S et al. |
Sphingosylphosphorylcholine and sphingosine-1-phosphate mobilize cytosolic calcium through different mechanisms in human airway epithelial cells. |
1998 |
Cell Calcium |
pmid:9924630
|
Lanterman MM and Saba JD |
Characterization of sphingosine kinase (SK) activity in Saccharomyces cerevisiae and isolation of SK-deficient mutants. |
1998 |
Biochem. J. |
pmid:9601083
|
Okamoto H et al. |
EDG1 is a functional sphingosine-1-phosphate receptor that is linked via a Gi/o to multiple signaling pathways, including phospholipase C activation, Ca2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibition. |
1998 |
J. Biol. Chem. |
pmid:9765227
|
Takeda H et al. |
Sphingomyelinase and ceramide inhibit formation of F-actin ring in and bone resorption by rabbit mature osteoclasts. |
1998 |
FEBS Lett. |
pmid:9490019
|
Kovács P et al. |
The effects of ceramide and its analogues on the secretion of the mucocyst content of Tetrahymena. |
1998 |
Cell. Mol. Biol. (Noisy-le-grand) |
pmid:9763202
|
Nagiec MM et al. |
The LCB4 (YOR171c) and LCB5 (YLR260w) genes of Saccharomyces encode sphingoid long chain base kinases. |
1998 |
J. Biol. Chem. |
pmid:9677363
|
Van Brocklyn JR et al. |
Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival. |
1998 |
J. Cell Biol. |
pmid:9660876
|
Mandala SM et al. |
Sphingoid base 1-phosphate phosphatase: a key regulator of sphingolipid metabolism and stress response. |
1998 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:9419344
|
Guo C et al. |
Differential stimulation of proline-rich tyrosine kinase 2 and mitogen-activated protein kinase by sphingosine 1-phosphate. |
1998 |
Eur. J. Biochem. |
pmid:9826186
|
Xia P et al. |
Tumor necrosis factor-alpha induces adhesion molecule expression through the sphingosine kinase pathway. |
1998 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:9826677
|
Meyer zu Heringdorf D et al. |
Sphingosine kinase-mediated Ca2+ signalling by G-protein-coupled receptors. |
1998 |
EMBO J. |
pmid:9582276
|
Noh SJ et al. |
Different signaling pathway between sphingosine-1-phosphate and lysophosphatidic acid in Xenopus oocytes: functional coupling of the sphingosine-1-phosphate receptor to PLC-xbeta in Xenopus oocytes. |
1998 |
J. Cell. Physiol. |
pmid:9648929
|
Lee MJ et al. |
Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1. |
1998 |
Science |
pmid:9488656
|
van Echten-Deckert G et al. |
Phosphorylated cis-4-methylsphingosine mimics the mitogenic effect of sphingosine-1-phosphate in Swiss 3T3 fibroblasts. |
1998 |
J. Biol. Chem. |
pmid:9722598
|
Melendez A et al. |
FcgammaRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular trafficking. |
1998 |
J. Biol. Chem. |
pmid:9545263
|
Spiegel S et al. |
Roles of sphingosine-1-phosphate in cell growth, differentiation, and death. |
1998 |
Biochemistry Mosc. |
pmid:9526097
|