| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
| Anemia, Aplastic | D000741 | 6 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Chemical and Drug Induced Liver Injury | D056486 | 39 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Proteinuria | D011507 | 30 associated lipids |
| Thyroid Neoplasms | D013964 | 33 associated lipids |
Sphingosine 1-phosphate
Sphingosine 1-phosphate is a lipid of Sphingolipids (SP) class. Sphingosine 1-phosphate is associated with abnormalities such as Infection, Painful Bladder Syndrome, Atherosclerosis, Hyperglycemia and Rheumatoid Arthritis. The involved functions are known as Phosphorylation, Regulation, enzyme activity, Energy Absorption and Vascular Permeability. Sphingosine 1-phosphate often locates in Endothelium, Tissue membrane, Vascular System, Protoplasm and Microfilaments. The associated genes with Sphingosine 1-phosphate are MBTPS1 gene, FBXL15 gene, TEK gene, NTRK1 gene and Gene Family. The related lipids are Promega, Lipopolysaccharides, lysophosphatidic acid, Lysophosphatidylcholines and Lysophospholipids. The related experimental models are Knock-out, Mouse Model, Transgenic Model, Disease model and Experimental Autoimmune Encephalomyelitis.
Cross Reference
Introduction
To understand associated biological information of Sphingosine 1-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Sphingosine 1-phosphate?
Sphingosine 1-phosphate is suspected in Lymphopenia, Ischemia, Infection, Atherosclerosis, Multiple Sclerosis, Asthma and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Sphingosine 1-phosphate
PubChem Associated disorders and diseases
What pathways are associated with Sphingosine 1-phosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Sphingosine 1-phosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Sphingosine 1-phosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Sphingosine 1-phosphate?
Knock-out
Knock-out are used in the study 'Sphingosine 1-phosphate-dependent trafficking of peritoneal B cells requires functional NFkappaB-inducing kinase in stromal cells.' (Kunisawa J et al., 2008), Knock-out are used in the study 'Connective tissue growth factor (CTGF/CCN2) mediates angiogenic effect of S1P in human dermal microvascular endothelial cells.' (Markiewicz M et al., 2011), Knock-out are used in the study 'Chasing sphingosine-1-phosphate, a lipid mediator for cardiomyocyte survival.' (Yang Q, 2007), Knock-out are used in the study 'Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function.' (Idzko M et al., 2006) and Knock-out are used in the study 'Platelet endothelial cell adhesion molecule-1 modulates endothelial cell motility through the small G-protein Rho.' (Gratzinger D et al., 2003).
Mouse Model
Mouse Model are used in the study 'Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: role of cortactin.' (Arce FT et al., 2008), Mouse Model are used in the study 'Sequential delivery of vascular endothelial growth factor and sphingosine 1-phosphate for angiogenesis.' (Tengood JE et al., 2010), Mouse Model are used in the study 'S1P(5) is required for sphingosine 1-phosphate-induced autophagy in human prostate cancer PC-3 cells.' (Chang CL et al., 2009), Mouse Model are used in the study 'Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.' (Hughes JE et al., 2008) and Mouse Model are used in the study 'The alliance of sphingosine-1-phosphate and its receptors in immunity.' (Rivera J et al., 2008).
Transgenic Model
Transgenic Model are used in the study 'Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation.' (Augé N et al., 2004), Transgenic Model are used in the study 'Sphingosine-1-phosphate antibodies as potential agents in the treatment of cancer and age-related macular degeneration.' (Sabbadini RA, 2011) and Transgenic Model are used in the study 'Still benched on its way to the bedside: sphingosine kinase 1 as an emerging target in cancer chemotherapy.' (Gault CR and Obeid LM, 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Sphingosine 1-phosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Molderings GJ et al. | S1P-receptors in PC12 and transfected HEK293 cells: molecular targets of hypotensive imidazoline I(1) receptor ligands. | 2007 | Neurochem. Int. | pmid:17559976 |
| Huwiler A and Zangemeister-Wittke U | Targeting the conversion of ceramide to sphingosine 1-phosphate as a novel strategy for cancer therapy. | 2007 | Crit. Rev. Oncol. Hematol. | pmid:17560117 |
| Chilton L et al. | Evidence of intercellular coupling between co-cultured adult rabbit ventricular myocytes and myofibroblasts. | 2007 | J. Physiol. (Lond.) | pmid:17569734 |
| Kontush A et al. | Preferential sphingosine-1-phosphate enrichment and sphingomyelin depletion are key features of small dense HDL3 particles: relevance to antiapoptotic and antioxidative activities. | 2007 | Arterioscler. Thromb. Vasc. Biol. | pmid:17569880 |
| Dyatlovitskaya EV | The role of lysosphingolipids in the regulation of biological processes. | 2007 | Biochemistry Mosc. | pmid:17573701 |
| Furukawa A et al. | Production of nerve growth factor enhanced in cultured mouse astrocytes by glycerophospholipids, sphingolipids, and their related compounds. | 2007 | Mol. Cell. Biochem. | pmid:17577630 |
| Brizuela L et al. | Sphingosine-1-phosphate stimulates aldosterone secretion through a mechanism involving the PI3K/PKB and MEK/ERK 1/2 pathways. | 2007 | J. Lipid Res. | pmid:17609523 |
| Jin ZQ et al. | A sphingosine kinase 1 mutation sensitizes the myocardium to ischemia/reperfusion injury. | 2007 | Cardiovasc. Res. | pmid:17610857 |
| Karahatay S et al. | Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma (HNSCC): attenuation of C(18)-ceramide in HNSCC tumors correlates with lymphovascular invasion and nodal metastasis. | 2007 | Cancer Lett. | pmid:17619081 |
| Blondeau N et al. | Distribution of sphingosine kinase activity and mRNA in rodent brain. | 2007 | J. Neurochem. | pmid:17623044 |
| Itagaki K et al. | Sphingosine 1-phosphate has dual functions in the regulation of endothelial cell permeability and Ca2+ metabolism. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17626797 |
| Pan CY et al. | Lysophospholipids regulate excitability and exocytosis in cultured bovine chromaffin cells. | 2007 | J. Neurochem. | pmid:17630986 |
| Kim K et al. | Sphingosine 1-phosphate (S1P) induces shape change in rat C6 glioma cells through the S1P2 receptor: development of an agonist for S1P receptors. | 2007 | J. Pharm. Pharmacol. | pmid:17637200 |
| Kurashima Y et al. | Sphingosine 1-phosphate-mediated trafficking of pathogenic Th2 and mast cells for the control of food allergy. | 2007 | J. Immunol. | pmid:17641024 |
| Kawanabe T et al. | Sphingosine 1-phosphate accelerates wound healing in diabetic mice. | 2007 | J. Dermatol. Sci. | pmid:17643267 |
| Osada M et al. | Involvement of sphingosine 1-phosphate, a platelet-derived bioactive lipid, in contraction of mesangium cells. | 2007 | J. Biochem. | pmid:17646176 |
| Weigert A et al. | Tumor cell apoptosis polarizes macrophages role of sphingosine-1-phosphate. | 2007 | Mol. Biol. Cell | pmid:17652460 |
| Meacci E et al. | Sphingosine kinase activity is required for myogenic differentiation of C2C12 myoblasts. | 2008 | J. Cell. Physiol. | pmid:17654519 |
| Oskeritzian CA et al. | Sphingosine-1-phosphate in allergic responses, asthma and anaphylaxis. | 2007 | Pharmacol. Ther. | pmid:17669501 |
| Xu M et al. | Sphingosine 1-phosphate rapidly increases endothelial barrier function independently of VE-cadherin but requires cell spreading and Rho kinase. | 2007 | Am. J. Physiol., Cell Physiol. | pmid:17670896 |
| Santucci MB et al. | Sphingosine 1-phosphate promotes antigen processing and presentation to CD4+ T cells in Mycobacterium tuberculosis-infected monocytes. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17673170 |
| Iwaki S et al. | Intracellular trafficking pathway of yeast long-chain base kinase Lcb4, from its synthesis to its degradation. | 2007 | J. Biol. Chem. | pmid:17686782 |
| Omori K et al. | Edaravone mimics sphingosine-1-phosphate-induced endothelial barrier enhancement in human microvascular endothelial cells. | 2007 | Am. J. Physiol., Cell Physiol. | pmid:17686998 |
| Argraves KM and Argraves WS | HDL serves as a S1P signaling platform mediating a multitude of cardiovascular effects. | 2007 | J. Lipid Res. | pmid:17698855 |
| Min J et al. | (Dihydro)ceramide synthase 1 regulated sensitivity to cisplatin is associated with the activation of p38 mitogen-activated protein kinase and is abrogated by sphingosine kinase 1. | 2007 | Mol. Cancer Res. | pmid:17699106 |
| Stradner MH et al. | Spingosine-1-phosphate stimulates proliferation and counteracts interleukin-1 induced nitric oxide formation in articular chondrocytes. | 2008 | Osteoarthr. Cartil. | pmid:17703957 |
| Phan VH et al. | Disruption of sphingolipid metabolism elicits apoptosis-associated reproductive defects in Drosophila. | 2007 | Dev. Biol. | pmid:17706961 |
| Smicun Y et al. | S1P and LPA have an attachment-dependent regulatory effect on invasion of epithelial ovarian cancer cells. | 2007 | Gynecol. Oncol. | pmid:17716713 |
| Liu Q et al. | FTY720 demonstrates promising preclinical activity for chronic lymphocytic leukemia and lymphoblastic leukemia/lymphoma. | 2008 | Blood | pmid:17761520 |
| Klingenberg R et al. | Sphingosine-1-phosphate analogue FTY720 causes lymphocyte redistribution and hypercholesterolemia in ApoE-deficient mice. | 2007 | Arterioscler. Thromb. Vasc. Biol. | pmid:17761943 |
| Tani M et al. | Sphingosine 1-phosphate (S1P) inhibits monocyte-endothelial cell interaction by regulating of RhoA activity. | 2007 | FEBS Lett. | pmid:17825823 |
| Wacker BK et al. | Endothelial cell migration on RGD-peptide-containing PEG hydrogels in the presence of sphingosine 1-phosphate. | 2008 | Biophys. J. | pmid:17827231 |
| Shimizu T et al. | Sphingosine 1-phosphate receptor 2 negatively regulates neointimal formation in mouse arteries. | 2007 | Circ. Res. | pmid:17872461 |
| Kunisawa J et al. | Sphingosine 1-phosphate dependence in the regulation of lymphocyte trafficking to the gut epithelium. | 2007 | J. Exp. Med. | pmid:17875673 |
| Kim DH et al. | Elevation of sphingoid base 1-phosphate as a potential contributor to hepatotoxicity in fumonisin B1-exposed mice. | 2007 | Arch. Pharm. Res. | pmid:17879749 |
| Siow DL and Wattenberg BW | An assay system for measuring the acute production of sphingosine 1-phosphate in intact monolayers. | 2007 | Anal. Biochem. | pmid:17884005 |
| Kim M et al. | Isoflurane mediates protection from renal ischemia-reperfusion injury via sphingosine kinase and sphingosine-1-phosphate-dependent pathways. | 2007 | Am. J. Physiol. Renal Physiol. | pmid:17898040 |
| Hsieh HL et al. | Sphingosine 1-phosphate induces EGFR expression via Akt/NF-kappaB and ERK/AP-1 pathways in rat vascular smooth muscle cells. | 2008 | J. Cell. Biochem. | pmid:17902169 |
| Cai Q et al. | Validation of fumonisin biomarkers in F344 rats. | 2007 | Toxicol. Appl. Pharmacol. | pmid:17904604 |
| Alvarez SE et al. | Autocrine and paracrine roles of sphingosine-1-phosphate. | 2007 | Trends Endocrinol. Metab. | pmid:17904858 |
| Melendez AJ | Sphingosine kinase signalling in immune cells: potential as novel therapeutic targets. | 2008 | Biochim. Biophys. Acta | pmid:17913601 |
| Johnstone ED et al. | Epidermal growth factor and sphingosine-1-phosphate stimulate Na+/H+ exchanger activity in the human placental syncytiotrophoblast. | 2007 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:17913870 |
| Miron VE et al. | FTY720 modulates human oligodendrocyte progenitor process extension and survival. | 2008 | Ann. Neurol. | pmid:17918267 |
| Harvey KA et al. | Trans-fatty acids induce pro-inflammatory responses and endothelial cell dysfunction. | 2008 | Br. J. Nutr. | pmid:17925051 |
| Sato K et al. | Critical role of ABCA1 transporter in sphingosine 1-phosphate release from astrocytes. | 2007 | J. Neurochem. | pmid:17931360 |
| Lobo MK et al. | Genetic control of instrumental conditioning by striatopallidal neuron-specific S1P receptor Gpr6. | 2007 | Nat. Neurosci. | pmid:17934457 |
| Murph M and Mills GB | Targeting the lipids LPA and S1P and their signalling pathways to inhibit tumour progression. | 2007 | Expert Rev Mol Med | pmid:17935635 |
| Jang S et al. | Changes in iNOS, GFAP and NR1 expression in various brain regions and elevation of sphingosine-1-phosphate in serum after immobilized stress. | 2008 | Neurochem. Res. | pmid:17940874 |
| Zanin M et al. | Trophic action of sphingosine 1-phosphate in denervated rat soleus muscle. | 2008 | Am. J. Physiol., Cell Physiol. | pmid:17942639 |
| Samy ET et al. | Cutting edge: Modulation of intestinal autoimmunity and IL-2 signaling by sphingosine kinase 2 independent of sphingosine 1-phosphate. | 2007 | J. Immunol. | pmid:17947634 |
| Czeloth N et al. | Sphingosine-1 phosphate signaling regulates positioning of dendritic cells within the spleen. | 2007 | J. Immunol. | pmid:17947659 |
| Maceyka M et al. | Measurement of mammalian sphingosine-1-phosphate phosphohydrolase activity in vitro and in vivo. | 2007 | Meth. Enzymol. | pmid:17954251 |
| Mitra P et al. | A rapid and sensitive method to measure secretion of sphingosine-1-phosphate. | 2007 | Meth. Enzymol. | pmid:17954252 |
| Martino A | Sphingosine 1-phosphate as a novel immune regulator of dendritic cells. | 2007 | J. Biosci. | pmid:17954981 |
| Walzer T et al. | Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor. | 2007 | Nat. Immunol. | pmid:17965716 |
| Watterson KR et al. | Regulation of fibroblast functions by lysophospholipid mediators: potential roles in wound healing. | 2007 Sep-Oct | Wound Repair Regen | pmid:17971005 |
| Braun A et al. | Paucity of pericytes in germinal matrix vasculature of premature infants. | 2007 | J. Neurosci. | pmid:17978043 |
| Van Brocklyn JR | Sphingolipid signaling pathways as potential therapeutic targets in gliomas. | 2007 | Mini Rev Med Chem | pmid:17979800 |
| Yatomi Y | Plasma sphingosine 1-phosphate metabolism and analysis. | 2008 | Biochim. Biophys. Acta | pmid:17980708 |
| Lee YM et al. | A novel method to quantify sphingosine 1-phosphate by immobilized metal affinity chromatography (IMAC). | 2007 | Prostaglandins Other Lipid Mediat. | pmid:17991617 |
| Ullrich T et al. | Synthesis and immobilization of erythro-C14-omega-aminosphingosine-1-phosphate as a potential tool for affinity chromatography. | 2008 | ChemMedChem | pmid:18000941 |
| Srinivasan S et al. | Sphingosine-1-phosphate reduces CD4+ T-cell activation in type 1 diabetes through regulation of hypoxia-inducible factor short isoform I.1 and CD69. | 2008 | Diabetes | pmid:18003758 |
| Zabielski P et al. | Bezafibrate decreases growth stimulatory action of the sphingomyelin signaling pathway in regenerating rat liver. | 2008 | Prostaglandins Other Lipid Mediat. | pmid:18024222 |
| Landeen LK et al. | Mechanisms of the negative inotropic effects of sphingosine-1-phosphate on adult mouse ventricular myocytes. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18024550 |
| Schwab SR and Cyster JG | Finding a way out: lymphocyte egress from lymphoid organs. | 2007 | Nat. Immunol. | pmid:18026082 |
| Salomone S et al. | Analysis of sphingosine 1-phosphate receptors involved in constriction of isolated cerebral arteries with receptor null mice and pharmacological tools. | 2008 | Br. J. Pharmacol. | pmid:18026125 |
| Borges S et al. | Discrete influx events refill depleted Ca2+ stores in a chick retinal neuron. | 2008 | J. Physiol. (Lond.) | pmid:18033816 |
| Ledgerwood LG et al. | The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics. | 2008 | Nat. Immunol. | pmid:18037890 |
| Herzinger T et al. | Sphingosine-1-phosphate signaling and the skin. | 2007 | Am J Clin Dermatol | pmid:18039015 |
| Nussbaumer P et al. | An efficient, one-pot synthesis of various ceramide 1-phosphates from sphingosine 1-phosphate. | 2008 | Chem. Phys. Lipids | pmid:18039471 |
| Stuebe S et al. | Sphingosine-1-phosphate and endothelin-1 induce the expression of rgs16 protein in cardiac myocytes by transcriptional activation of the rgs16 gene. | 2008 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:18046543 |
| Wong RC et al. | Anti-apoptotic effect of sphingosine-1-phosphate and platelet-derived growth factor in human embryonic stem cells. | 2007 | Stem Cells Dev. | pmid:18047416 |
| Ruckhäberle E et al. | Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer. | 2008 | Breast Cancer Res. Treat. | pmid:18058224 |
| Singh IN and Hall ED | Multifaceted roles of sphingosine-1-phosphate: how does this bioactive sphingolipid fit with acute neurological injury? | 2008 | J. Neurosci. Res. | pmid:18058948 |
| Mulders AC et al. | Effects of sphingosine-1-phosphate and sphingosylphosphorylcholine on intracellular Ca2+ and cell death in prostate cancer cell lines. | 2007 | Auton Autacoid Pharmacol | pmid:18076478 |
| Strochlic L et al. | A role for S1P signalling in axon guidance in the Xenopus visual system. | 2008 | Development | pmid:18077591 |
| Simonaro CM et al. | Mechanism of glycosaminoglycan-mediated bone and joint disease: implications for the mucopolysaccharidoses and other connective tissue diseases. | 2008 | Am. J. Pathol. | pmid:18079441 |
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| Malchinkhuu E et al. | S1P(2) receptors mediate inhibition of glioma cell migration through Rho signaling pathways independent of PTEN. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18088600 |
| Fulton D et al. | Agonist-stimulated endothelial nitric oxide synthase activation and vascular relaxation. Role of eNOS phosphorylation at Tyr83. | 2008 | Circ. Res. | pmid:18096817 |
| Roztocil E et al. | Sphingosine-1-phosphate-induced oxygen free radical generation in smooth muscle cell migration requires Galpha12/13 protein-mediated phospholipase C activation. | 2007 | J. Vasc. Surg. | pmid:18155002 |
| Brunati AM et al. | Cross-talk between PDGF and S1P signalling elucidates the inhibitory effect and potential antifibrotic action of the immunomodulator FTY720 in activated HSC-cultures. | 2008 | Biochim. Biophys. Acta | pmid:18157950 |
| Gingras D et al. | Sphingosine-1-phosphate induces the association of membrane-type 1 matrix metalloproteinase with p130Cas in endothelial cells. | 2008 | FEBS Lett. | pmid:18164686 |
| Laviad EL et al. | Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate. | 2008 | J. Biol. Chem. | pmid:18165233 |
| Hammad SM et al. | Dual and distinct roles for sphingosine kinase 1 and sphingosine 1 phosphate in the response to inflammatory stimuli in RAW macrophages. | 2008 | Prostaglandins Other Lipid Mediat. | pmid:18166496 |
| Machida T et al. | Sphingosine 1-phosphate inhibits nitric oxide production induced by interleukin-1beta in rat vascular smooth muscle cells. | 2008 | J. Pharmacol. Exp. Ther. | pmid:18171908 |
| Lichte K et al. | Lysophospholipid receptor-mediated calcium signaling in human keratinocytes. | 2008 | J. Invest. Dermatol. | pmid:18172456 |
| Peest U et al. | S1P-lyase independent clearance of extracellular sphingosine 1-phosphate after dephosphorylation and cellular uptake. | 2008 | J. Cell. Biochem. | pmid:18172856 |
| Johann AM et al. | Apoptotic cell-derived sphingosine-1-phosphate promotes HuR-dependent cyclooxygenase-2 mRNA stabilization and protein expression. | 2008 | J. Immunol. | pmid:18178864 |
| Oskeritzian CA et al. | Distinct roles of sphingosine kinases 1 and 2 in human mast-cell functions. | 2008 | Blood | pmid:18178871 |
| Oyama O et al. | The lysophospholipid mediator sphingosine-1-phosphate promotes angiogenesis in vivo in ischaemic hindlimbs of mice. | 2008 | Cardiovasc. Res. | pmid:18187460 |
| Hadizadeh S et al. | Sphingosine-1-phosphate regulates the expression of the liver receptor homologue-1. | 2008 | Mol. Cell. Endocrinol. | pmid:18191017 |
| Yan G et al. | Activation of sphingosine kinase-1 mediates induction of endothelial cell proliferation and angiogenesis by epoxyeicosatrienoic acids. | 2008 | Cardiovasc. Res. | pmid:18192241 |
| Molderings GJ et al. | Characterization of an antiproliferative effect of imidazoline receptor ligands on PC12 cells. | 2007 Nov-Dec | Pharmacol Rep | pmid:18195472 |
| Lee KJ et al. | Determination of sphingosine kinase activity for cellular signaling studies. | 2008 | Anal. Chem. | pmid:18197698 |
| Dustin ML and Chakraborty AK | Tug of war at the exit door. | 2008 | Immunity | pmid:18199414 |
| Li X et al. | Basal and angiopoietin-1-mediated endothelial permeability is regulated by sphingosine kinase-1. | 2008 | Blood | pmid:18199826 |
| Patschan S et al. | Lipid mediators of autophagy in stress-induced premature senescence of endothelial cells. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18203850 |
| Eskan MA et al. | Sphingosine 1-phosphate 1 and TLR4 mediate IFN-beta expression in human gingival epithelial cells. | 2008 | J. Immunol. | pmid:18209079 |
| Sekiguchi M et al. | Role of sphingosine 1-phosphate in the pathogenesis of Sjögren's syndrome. | 2008 | J. Immunol. | pmid:18209090 |