| MeSH term | MeSH ID | Detail |
|---|---|---|
| Carcinoma, Lewis Lung | D018827 | 22 associated lipids |
| Neoplasm Invasiveness | D009361 | 23 associated lipids |
| Fibrosis | D005355 | 23 associated lipids |
| Neoplasms, Hormone-Dependent | D009376 | 23 associated lipids |
| Pulmonary Edema | D011654 | 23 associated lipids |
| Pulmonary Fibrosis | D011658 | 24 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Encephalomyelitis, Autoimmune, Experimental | D004681 | 26 associated lipids |
| Endotoxemia | D019446 | 27 associated lipids |
Sphingosine 1-phosphate
Sphingosine 1-phosphate is a lipid of Sphingolipids (SP) class. Sphingosine 1-phosphate is associated with abnormalities such as Infection, Painful Bladder Syndrome, Atherosclerosis, Hyperglycemia and Rheumatoid Arthritis. The involved functions are known as Phosphorylation, Regulation, enzyme activity, Energy Absorption and Vascular Permeability. Sphingosine 1-phosphate often locates in Endothelium, Tissue membrane, Vascular System, Protoplasm and Microfilaments. The associated genes with Sphingosine 1-phosphate are MBTPS1 gene, FBXL15 gene, TEK gene, NTRK1 gene and Gene Family. The related lipids are Promega, Lipopolysaccharides, lysophosphatidic acid, Lysophosphatidylcholines and Lysophospholipids. The related experimental models are Knock-out, Mouse Model, Transgenic Model, Disease model and Experimental Autoimmune Encephalomyelitis.
Cross Reference
Introduction
To understand associated biological information of Sphingosine 1-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Sphingosine 1-phosphate?
Sphingosine 1-phosphate is suspected in Lymphopenia, Ischemia, Infection, Atherosclerosis, Multiple Sclerosis, Asthma and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Sphingosine 1-phosphate
PubChem Associated disorders and diseases
What pathways are associated with Sphingosine 1-phosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Sphingosine 1-phosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Sphingosine 1-phosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Sphingosine 1-phosphate?
Knock-out
Knock-out are used in the study 'Sphingosine 1-phosphate-dependent trafficking of peritoneal B cells requires functional NFkappaB-inducing kinase in stromal cells.' (Kunisawa J et al., 2008), Knock-out are used in the study 'Connective tissue growth factor (CTGF/CCN2) mediates angiogenic effect of S1P in human dermal microvascular endothelial cells.' (Markiewicz M et al., 2011), Knock-out are used in the study 'Chasing sphingosine-1-phosphate, a lipid mediator for cardiomyocyte survival.' (Yang Q, 2007), Knock-out are used in the study 'Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function.' (Idzko M et al., 2006) and Knock-out are used in the study 'Platelet endothelial cell adhesion molecule-1 modulates endothelial cell motility through the small G-protein Rho.' (Gratzinger D et al., 2003).
Mouse Model
Mouse Model are used in the study 'Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: role of cortactin.' (Arce FT et al., 2008), Mouse Model are used in the study 'Sequential delivery of vascular endothelial growth factor and sphingosine 1-phosphate for angiogenesis.' (Tengood JE et al., 2010), Mouse Model are used in the study 'S1P(5) is required for sphingosine 1-phosphate-induced autophagy in human prostate cancer PC-3 cells.' (Chang CL et al., 2009), Mouse Model are used in the study 'Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.' (Hughes JE et al., 2008) and Mouse Model are used in the study 'The alliance of sphingosine-1-phosphate and its receptors in immunity.' (Rivera J et al., 2008).
Transgenic Model
Transgenic Model are used in the study 'Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation.' (Augé N et al., 2004), Transgenic Model are used in the study 'Sphingosine-1-phosphate antibodies as potential agents in the treatment of cancer and age-related macular degeneration.' (Sabbadini RA, 2011) and Transgenic Model are used in the study 'Still benched on its way to the bedside: sphingosine kinase 1 as an emerging target in cancer chemotherapy.' (Gault CR and Obeid LM, 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Sphingosine 1-phosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wang F and Fishman DA | Lysophosphatidic acid and invasion. | 2009 | Cancer Treat. Res. | pmid:19763441 |
| Yamane D et al. | Inhibition of sphingosine kinase by bovine viral diarrhea virus NS3 is crucial for efficient viral replication and cytopathogenesis. | 2009 | J. Biol. Chem. | pmid:19293152 |
| Green DS et al. | Human immunodeficiency virus type 1 gp120 reprogramming of CD4+ T-cell migration provides a mechanism for lymphadenopathy. | 2009 | J. Virol. | pmid:19297493 |
| Yu H et al. | Roles of extracellular and intracellular sphingosine 1-phosphate in cell migration. | 2009 | Genes Cells | pmid:19371379 |
| Guillermet-Guibert J et al. | Targeting the sphingolipid metabolism to defeat pancreatic cancer cell resistance to the chemotherapeutic gemcitabine drug. | 2009 | Mol. Cancer Ther. | pmid:19372554 |
| Hendriks-Balk MC et al. | Sphingosine-1-phosphate regulates RGS2 and RGS16 mRNA expression in vascular smooth muscle cells. | 2009 | Eur. J. Pharmacol. | pmid:19374869 |
| Nincheri P et al. | Sphingosine 1-phosphate induces differentiation of adipose tissue-derived mesenchymal stem cells towards smooth muscle cells. | 2009 | Cell. Mol. Life Sci. | pmid:19337690 |
| Schulz C et al. | Hematopoietic stem and progenitor cells: their mobilization and homing to bone marrow and peripheral tissue. | 2009 | Immunol. Res. | pmid:19340403 |
| Hernandez F et al. | Local effects of the sphingosine 1-phosphate on prostaglandin F2alpha-induced luteolysis in the pregnant rat. | 2009 | Mol. Reprod. Dev. | pmid:19645054 |
| Padmanabhan S et al. | Constitutively active GPR6 is located in the intracellular compartments. | 2009 | FEBS Lett. | pmid:19059244 |
| Brindley DN and Pilquil C | Lipid phosphate phosphatases and signaling. | 2009 | J. Lipid Res. | pmid:19066402 |
| Kennedy S et al. | Targeting sphingosine-1-phosphate signalling for cardioprotection. | 2009 | Curr Opin Pharmacol | pmid:19070545 |
| GarcÃa-Pacios M et al. | Sphingosine-1-phosphate as an amphipathic metabolite: its properties in aqueous and membrane environments. | 2009 | Biophys. J. | pmid:19720028 |
| Jang C et al. | Angiopoietin-2 exocytosis is stimulated by sphingosine-1-phosphate in human blood and lymphatic endothelial cells. | 2009 | Arterioscler. Thromb. Vasc. Biol. | pmid:19112163 |
| Bergelin N et al. | Sphingosine kinase as an oncogene: autocrine sphingosine 1-phosphate modulates ML-1 thyroid carcinoma cell migration by a mechanism dependent on protein kinase C-alpha and ERK1/2. | 2009 | Endocrinology | pmid:19116345 |
| Whetzel AM et al. | Sphingosine-1-phosphate inhibits high glucose-mediated ERK1/2 action in endothelium through induction of MAP kinase phosphatase-3. | 2009 | Am. J. Physiol., Cell Physiol. | pmid:19091959 |
| Li X et al. | Fenretinide inhibits myeloma cell growth, osteoclastogenesis and osteoclast viability. | 2009 | Cancer Lett. | pmid:19446953 |
| Sim-Selley LJ et al. | Sphingosine-1-phosphate receptors mediate neuromodulatory functions in the CNS. | 2009 | J. Neurochem. | pmid:19493165 |
| Knapp M et al. | Plasma sphingosine-1-phosphate concentration is reduced in patients with myocardial infarction. | 2009 | Med. Sci. Monit. | pmid:19721401 |
| Rapizzi E et al. | Sphingosine 1-phosphate increases glucose uptake through trans-activation of insulin receptor. | 2009 | Cell. Mol. Life Sci. | pmid:19662499 |
| Haberberger RV et al. | Role of sphingosine kinase 1 in allergen-induced pulmonary vascular remodeling and hyperresponsiveness. | 2009 | J. Allergy Clin. Immunol. | pmid:19665772 |
| Kim CH | Reining in FoxP3(+) regulatory T cells by the sphingosine 1-phosphate-S1P1 axis. | 2009 | Immunol. Cell Biol. | pmid:19652661 |
| Sarai K et al. | Endothelial barrier protection by FTY720 under hyperglycemic condition: involvement of focal adhesion kinase, small GTPases, and adherens junction proteins. | 2009 | Am. J. Physiol., Cell Physiol. | pmid:19657053 |
| Ren S et al. | Transforming growth factor-beta2 upregulates sphingosine kinase-1 activity, which in turn attenuates the fibrotic response to TGF-beta2 by impeding CTGF expression. | 2009 | Kidney Int. | pmid:19657322 |
| Grabski AD et al. | Sphingosine-1-phosphate receptor-2 regulates expression of smooth muscle alpha-actin after arterial injury. | 2009 | Arterioscler. Thromb. Vasc. Biol. | pmid:19608972 |
| Wetter JA et al. | Utilization of the Tango beta-arrestin recruitment technology for cell-based EDG receptor assay development and interrogation. | 2009 | J Biomol Screen | pmid:19726785 |
| Zebol JR et al. | The CCT/TRiC chaperonin is required for maturation of sphingosine kinase 1. | 2009 | Int. J. Biochem. Cell Biol. | pmid:18775504 |
| Caballero S et al. | Anti-sphingosine-1-phosphate monoclonal antibodies inhibit angiogenesis and sub-retinal fibrosis in a murine model of laser-induced choroidal neovascularization. | 2009 | Exp. Eye Res. | pmid:18723015 |
| Okada T et al. | Sphingosine kinase/sphingosine 1-phosphate signalling in central nervous system. | 2009 | Cell. Signal. | pmid:18694820 |
| Mochizuki N | Vascular integrity mediated by vascular endothelial cadherin and regulated by sphingosine 1-phosphate and angiopoietin-1. | 2009 | Circ. J. | pmid:19838001 |
| Hancke K et al. | Ovarian transplantation for fertility preservation in a sheep model: can follicle loss be prevented by antiapoptotic sphingosine-1-phosphate administration? | 2009 | Gynecol. Endocrinol. | pmid:19906004 |
| Hla T | Plugging vascular leak by sphingosine kinase from bone marrow progenitor cells. | 2009 | Circ. Res. | pmid:19797192 |
| Gratschev D et al. | Sphingosine kinase as a regulator of calcium entry through autocrine sphingosine 1-phosphate signaling in thyroid FRTL-5 cells. | 2009 | Endocrinology | pmid:19797403 |
| Xiang Y et al. | Discovery of novel sphingosine kinase 1 inhibitors. | 2009 | Bioorg. Med. Chem. Lett. | pmid:19800228 |
| Schnitzer SE et al. | Hypoxia enhances sphingosine kinase 2 activity and provokes sphingosine-1-phosphate-mediated chemoresistance in A549 lung cancer cells. | 2009 | Mol. Cancer Res. | pmid:19240180 |
| Kuehnel MP et al. | Sphingosine-1-phosphate receptors stimulate macrophage plasma-membrane actin assembly via ADP release, ATP synthesis and P2X7R activation. | 2009 | J. Cell. Sci. | pmid:19174470 |
| Kuehnel MP et al. | Lipids regulate P2X7-receptor-dependent actin assembly by phagosomes via ADP translocation and ATP synthesis in the phagosome lumen. | 2009 | J. Cell. Sci. | pmid:19174471 |
| Sensken SC and Gräler MH | [Sphingolipids and their medical impact]. | 2009 | Dtsch. Med. Wochenschr. | pmid:19180419 |
| Karliner JS | Sphingosine kinase and sphingosine 1-phosphate in cardioprotection. | 2009 | J. Cardiovasc. Pharmacol. | pmid:19247197 |
| Bandhuvula P et al. | Sphingosine 1-phosphate lyase enzyme assay using a BODIPY-labeled substrate. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19250638 |
| Pasquaré SJ et al. | Age-related changes in the metabolization of phosphatidic acid in rat cerebral cortex synaptosomes. | 2009 | Arch. Biochem. Biophys. | pmid:19691145 |
| Xu Y et al. | Lipid generation and signaling in ovarian cancer. | 2009 | Cancer Treat. Res. | pmid:19763440 |
| Sali M et al. | Exploiting immunotherapy in Mycobacterium tuberculosis-infected mice: sphingosine 1-phosphate treatment results in a protective or detrimental effect depending on the stage of infection. | 2009 Jan-Mar | Int J Immunopathol Pharmacol | pmid:19309565 |
| Syuto T et al. | Mammalian Diaphanous (mDia) may be involved in the signal transduction of sphingosine-1-phosphate on developing actin stress fiber of human fibroblasts. | 2009 Jul-Aug | Wound Repair Regen | pmid:19614924 |
| Maiese K | Choices and outcomes: Extending basic biology to clinical care. | 2009 Jul-Aug | Oxid Med Cell Longev | pmid:20592765 |
| Vessey DA et al. | Sphingosine protects aging hearts from ischemia/reperfusion injury: Superiority to sphingosine 1-phosphate and ischemic pre- and post-conditioning. | 2009 Jul-Aug | Oxid Med Cell Longev | pmid:20592769 |
| Voelkel NF and Spiegel S | Why is effective treatment of asthma so difficult? An integrated systems biology hypothesis of asthma. | 2009 Nov-Dec | Immunol. Cell Biol. | pmid:19546879 |
| Bode C et al. | Erythrocytes serve as a reservoir for cellular and extracellular sphingosine 1-phosphate. | 2010 | J. Cell. Biochem. | pmid:20186882 |
| Ikeda H et al. | Plasma concentration of bioactive lipid mediator sphingosine 1-phosphate is reduced in patients with chronic hepatitis C. | 2010 | Clin. Chim. Acta | pmid:20188085 |
| Pereira JP et al. | A role for S1P and S1P1 in immature-B cell egress from mouse bone marrow. | 2010 | PLoS ONE | pmid:20174580 |
| Yu XQ et al. | Pharmacokinetic/pharmacodynamic modelling of 2-acetyl-4(5)-tetrahydroxybutyl imidazole-induced peripheral lymphocyte sequestration through increasing lymphoid sphingosine 1-phosphate. | 2010 | Xenobiotica | pmid:20175664 |
| Su SC et al. | Annexin 2 regulates endothelial morphogenesis by controlling AKT activation and junctional integrity. | 2010 | J. Biol. Chem. | pmid:20947498 |
| Chi XX and Nicol GD | The sphingosine 1-phosphate receptor, S1PRâ‚, plays a prominent but not exclusive role in enhancing the excitability of sensory neurons. | 2010 | J. Neurophysiol. | pmid:20844107 |
| Józefowski S et al. | Ceramide and ceramide 1-phosphate are negative regulators of TNF-α production induced by lipopolysaccharide. | 2010 | J. Immunol. | pmid:21041721 |
| Wuertz CM et al. | p63RhoGEF--a key mediator of angiotensin II-dependent signaling and processes in vascular smooth muscle cells. | 2010 | FASEB J. | pmid:20739613 |
| Chumanevich AA et al. | Suppression of colitis-driven colon cancer in mice by a novel small molecule inhibitor of sphingosine kinase. | 2010 | Carcinogenesis | pmid:20688834 |
| Bourquin F et al. | Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. | 2010 | Structure | pmid:20696404 |
| Hoefer J et al. | Sphingosine-1-phosphate-dependent activation of p38 MAPK maintains elevated peripheral resistance in heart failure through increased myogenic vasoconstriction. | 2010 | Circ. Res. | pmid:20671234 |
| Tengood JE et al. | Sequential delivery of vascular endothelial growth factor and sphingosine 1-phosphate for angiogenesis. | 2010 | Biomaterials | pmid:20674008 |
| Jee BC et al. | Effect of sphingosine-1-phosphate supplementation on follicular integrity of vitrified-warmed mouse ovarian grafts. | 2010 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:20674140 |
| Zhang G et al. | Sphingosine-1-phosphate prevents permeability increases via activation of endothelial sphingosine-1-phosphate receptor 1 in rat venules. | 2010 | Am. J. Physiol. Heart Circ. Physiol. | pmid:20729401 |
| De Luca T et al. | Reciprocal relationship between cytosolic NADH and ENOX2 inhibition triggers sphingolipid-induced apoptosis in HeLa cells. | 2010 | J. Cell. Biochem. | pmid:20518072 |
| Howard C et al. | Dental pulp stem cell migration. | 2010 | J Endod | pmid:21092813 |
| Roviezzo F et al. | Systemic administration of sphingosine-1-phosphate increases bronchial hyperresponsiveness in the mouse. | 2010 | Am. J. Respir. Cell Mol. Biol. | pmid:19556602 |
| Im DS | Pharmacological tools for lysophospholipid GPCRs: development of agonists and antagonists for LPA and S1P receptors. | 2010 | Acta Pharmacol. Sin. | pmid:20729877 |
| He X et al. | Deregulation of sphingolipid metabolism in Alzheimer's disease. | 2010 | Neurobiol. Aging | pmid:18547682 |
| Blachnio-Zabielska A et al. | Effect of high fat diet enriched with unsaturated and diet rich in saturated fatty acids on sphingolipid metabolism in rat skeletal muscle. | 2010 | J. Cell. Physiol. | pmid:20568228 |
| Deshpande GP et al. | Effects of sphingosine-1-phosphate on acute contractile heart failure (ACHF). | 2010 | Cardiovasc Drugs Ther | pmid:20838867 |
| Gil PR et al. | Sphingosine 1-phosphate mediates chemotaxis of human primary fibroblasts via the S1P-receptor subtypes S1P₠and S1P₃ and Smad-signalling. | 2010 | Cytoskeleton (Hoboken) | pmid:20857421 |
| Dudek SM et al. | Abl tyrosine kinase phosphorylates nonmuscle Myosin light chain kinase to regulate endothelial barrier function. | 2010 | Mol. Biol. Cell | pmid:20861316 |
| Lan T et al. | Determination of sphingosine kinase activity in biological samples by liquid chromatography-tandem mass spectrometry. | 2010 | Biomed. Chromatogr. | pmid:20352614 |
| Strub GM et al. | Extracellular and intracellular actions of sphingosine-1-phosphate. | 2010 | Adv. Exp. Med. Biol. | pmid:20919652 |
| Oskouian B and Saba JD | Cancer treatment strategies targeting sphingolipid metabolism. | 2010 | Adv. Exp. Med. Biol. | pmid:20919655 |
| Wang F et al. | Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice. | 2010 | J. Clin. Invest. | pmid:20978351 |
| Serra M and Saba JD | Sphingosine 1-phosphate lyase, a key regulator of sphingosine 1-phosphate signaling and function. | 2010 | Adv. Enzyme Regul. | pmid:19914275 |
| Yamamoto Y et al. | Increased expression of enzymes for sphingosine 1-phosphate turnover and signaling in human decidua during late pregnancy. | 2010 | Biol. Reprod. | pmid:20007411 |
| Wang S et al. | A polysaccharide, MDG-1, induces S1P1 and bFGF expression and augments survival and angiogenesis in the ischemic heart. | 2010 | Glycobiology | pmid:20008963 |
| McDonald RA et al. | The sphingosine kinase inhibitor N,N-dimethylsphingosine inhibits neointimal hyperplasia. | 2010 | Br. J. Pharmacol. | pmid:20015089 |
| Mair KM et al. | Interaction between anandamide and sphingosine-1-phosphate in mediating vasorelaxation in rat coronary artery. | 2010 | Br. J. Pharmacol. | pmid:20718749 |
| Herzog C et al. | Intravenous sphingosylphosphorylcholine protects ischemic and postischemic myocardial tissue in a mouse model of myocardial ischemia/reperfusion injury. | 2010 | Mediators Inflamm. | pmid:21274265 |
| Bonnaud S et al. | Sphingosine-1-phosphate activates the AKT pathway to protect small intestines from radiation-induced endothelial apoptosis. | 2010 | Cancer Res. | pmid:21118968 |
| Coelho RP et al. | Sphingosine-1-phosphate and oligodendrocytes: from cell development to the treatment of multiple sclerosis. | 2010 | Prostaglandins Other Lipid Mediat. | pmid:19808013 |
| He X et al. | Sphingosine-1-phosphate mediates proliferation maintaining the multipotency of human adult bone marrow and adipose tissue-derived stem cells. | 2010 | J Mol Cell Biol | pmid:20584786 |
| Thangada S et al. | Cell-surface residence of sphingosine 1-phosphate receptor 1 on lymphocytes determines lymphocyte egress kinetics. | 2010 | J. Exp. Med. | pmid:20584883 |
| Baker DA et al. | Genetic sphingosine kinase 1 deficiency significantly decreases synovial inflammation and joint erosions in murine TNF-alpha-induced arthritis. | 2010 | J. Immunol. | pmid:20644167 |
| Lan T et al. | Berberine ameliorates renal injury in diabetic C57BL/6 mice: Involvement of suppression of SphK-S1P signaling pathway. | 2010 | Arch. Biochem. Biophys. | pmid:20646989 |
| Adamson RH et al. | Sphingosine-1-phosphate modulation of basal permeability and acute inflammatory responses in rat venular microvessels. | 2010 | Cardiovasc. Res. | pmid:20542878 |
| Seo J et al. | Sphingosine-1-phosphate signaling in human submandibular cells. | 2010 | J. Dent. Res. | pmid:20651091 |
| Sattler KJ et al. | Sphingosine 1-phosphate levels in plasma and HDL are altered in coronary artery disease. | 2010 | Basic Res. Cardiol. | pmid:20652276 |
| Kelly RF et al. | Ethanolamine is a novel STAT-3 dependent cardioprotective agent. | 2010 | Basic Res. Cardiol. | pmid:20938668 |
| Meacci E et al. | Functional interaction between TRPC1 channel and connexin-43 protein: a novel pathway underlying S1P action on skeletal myogenesis. | 2010 | Cell. Mol. Life Sci. | pmid:20614160 |
| Sumida GM and Stamer WD | Sphingosine-1-phosphate enhancement of cortical actomyosin organization in cultured human Schlemm's canal endothelial cell monolayers. | 2010 | Invest. Ophthalmol. Vis. Sci. | pmid:20592229 |
| Zhou Y et al. | Isoflurane posttreatment reduces neonatal hypoxic-ischemic brain injury in rats by the sphingosine-1-phosphate/phosphatidylinositol-3-kinase/Akt pathway. | 2010 | Stroke | pmid:20508187 |
| Pchejetski D et al. | Circulating sphingosine-1-phosphate inversely correlates with chemotherapy-induced weight gain during early breast cancer. | 2010 | Breast Cancer Res. Treat. | pmid:20535545 |
| Leong WI and Saba JD | S1P metabolism in cancer and other pathological conditions. | 2010 | Biochimie | pmid:20167244 |
| Ma B et al. | Stereochemistry-activity relationship of orally active tetralin S1P agonist prodrugs. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20188554 |
| Gangoiti P et al. | Control of metabolism and signaling of simple bioactive sphingolipids: Implications in disease. | 2010 | Prog. Lipid Res. | pmid:20193711 |
| Zabielski P et al. | The effect of high-fat diet on the sphingolipid pathway of signal transduction in regenerating rat liver. | 2010 | Prostaglandins Other Lipid Mediat. | pmid:20599517 |
| Tölle M et al. | Relevance of sphingolipids in the pleiotropic protective effects of high-density lipoproteins. | 2010 | Curr. Pharm. Des. | pmid:20196741 |
| Weigert A et al. | Cleavage of sphingosine kinase 2 by caspase-1 provokes its release from apoptotic cells. | 2010 | Blood | pmid:20197547 |