Stone ML et al. |
Sphingosine-1-phosphate receptor 1 agonism attenuates lung ischemia-reperfusion injury. |
2015 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:25910934
|
Farnoud AM et al. |
The Granuloma Response Controlling Cryptococcosis in Mice Depends on the Sphingosine Kinase 1-Sphingosine 1-Phosphate Pathway. |
2015 |
Infect. Immun. |
pmid:25895971
|
Chimen M et al. |
Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease. |
2015 |
Nat. Med. |
pmid:25894827
|
Pulli I et al. |
A novel chimeric aequorin fused with caveolin-1 reveals a sphingosine kinase 1-regulated Ca²⺠microdomain in the caveolar compartment. |
2015 |
Biochim. Biophys. Acta |
pmid:25892494
|
Urtz N et al. |
Sphingosine 1-Phosphate Produced by Sphingosine Kinase 2 Intrinsically Controls Platelet Aggregation In Vitro and In Vivo. |
2015 |
Circ. Res. |
pmid:26129975
|
Zankov DP and Ogita H |
Actin-tethered junctional complexes in angiogenesis and lymphangiogenesis in association with vascular endothelial growth factor. |
2015 |
Biomed Res Int |
pmid:25883953
|
Williams PA et al. |
Hypoxia augments outgrowth endothelial cell (OEC) sprouting and directed migration in response to sphingosine-1-phosphate (S1P). |
2015 |
PLoS ONE |
pmid:25875493
|
Moolenaar WH |
Introduction to the ECR special issue on lysophospholipids in biology. |
2015 |
Exp. Cell Res. |
pmid:25746723
|
Muñoz-Sáez E et al. |
Neuroprotective role of sphingosine-1-phosphate in L-BMAA treated neuroblastoma cells (SH-SY5Y). |
2015 |
Neurosci. Lett. |
pmid:25769802
|
Kang H et al. |
The Therapeutic Effects of Human Mesenchymal Stem Cells Primed with Sphingosine-1 Phosphate on Pulmonary Artery Hypertension. |
2015 |
Stem Cells Dev. |
pmid:25761906
|
Carrera I et al. |
A comparative evaluation of a novel vaccine in APP/PS1 mouse models of Alzheimer's disease. |
2015 |
Biomed Res Int |
pmid:25759822
|
Ueda N |
Ceramide-induced apoptosis in renal tubular cells: a role of mitochondria and sphingosine-1-phoshate. |
2015 |
Int J Mol Sci |
pmid:25751724
|
Zhao S and Li J |
Sphingosine-1-phosphate induces the migration of thyroid follicular carcinoma cells through the microRNA-17/PTK6/ERK1/2 pathway. |
2015 |
PLoS ONE |
pmid:25748447
|
Lin CC et al. |
Sphingosine-1-phosphate mediates ICAM-1-dependent monocyte adhesion through p38 MAPK and p42/p44 MAPK-dependent Akt activation. |
2015 |
PLoS ONE |
pmid:25734900
|
Zhang DD et al. |
Antinociceptive effects of FTY720 during trauma-induced neuropathic pain are mediated by spinal S1P receptors. |
2015 |
Biol. Chem. |
pmid:25720064
|
Schröder M et al. |
Subcellular distribution of FTY720 and FTY720-phosphate in immune cells - another aspect of Fingolimod action relevant for therapeutic application. |
2015 |
Biol. Chem. |
pmid:25720062
|
Koch A et al. |
Downregulation of sphingosine 1-phosphate (S1P) receptor 1 by dexamethasone inhibits S1P-induced mesangial cell migration. |
2015 |
Biol. Chem. |
pmid:25719311
|
Park ES et al. |
Tumor necrosis factor (TNF) receptor-associated factor (TRAF)-interacting protein (TRIP) negatively regulates the TRAF2 ubiquitin-dependent pathway by suppressing the TRAF2-sphingosine 1-phosphate (S1P) interaction. |
2015 |
J. Biol. Chem. |
pmid:25716317
|
Rhee SH et al. |
Pelvic organ prolapse is associated with alteration of sphingosine-1-phosphate/Rho-kinase signalling pathway in human vaginal wall. |
2015 |
J Obstet Gynaecol |
pmid:25692679
|
Oskeritzian CA et al. |
The sphingosine-1-phosphate/sphingosine-1-phosphate receptor 2 axis regulates early airway T-cell infiltration in murine mast cell-dependent acute allergic responses. |
2015 |
J. Allergy Clin. Immunol. |
pmid:25512083
|
Kurano M et al. |
LDL receptor and ApoE are involved in the clearance of ApoM-associated sphingosine 1-phosphate. |
2015 |
J. Biol. Chem. |
pmid:25505264
|
Roviezzo F et al. |
S1P-induced airway smooth muscle hyperresponsiveness and lung inflammation in vivo: molecular and cellular mechanisms. |
2015 |
Br. J. Pharmacol. |
pmid:25439580
|
Konstantinou D et al. |
Growth factors mediated differentiation of mesenchymal stem cells to cardiac polymicrotissue using hanging drop and bioreactor. |
2015 |
Cell Biol. Int. |
pmid:25492631
|
Pyne NJ and Kolesnick RN |
The life and work of Dr. Robert Bittman (1942-2014). |
2015 |
Biol. Chem. |
pmid:25473803
|
Hashimoto Y et al. |
Sphingosine-1-phosphate inhibits differentiation of C3H10T1/2 cells into adipocyte. |
2015 |
Mol. Cell. Biochem. |
pmid:25445169
|
Carroll B et al. |
Sphingolipids in the DNA damage response. |
2015 |
Adv Biol Regul |
pmid:25434743
|
Xiu L et al. |
Intracellular sphingosine 1-phosphate contributes to collagen expression of hepatic myofibroblasts in human liver fibrosis independent of its receptors. |
2015 |
Am. J. Pathol. |
pmid:25432063
|
Benesch MG et al. |
Regulation of autotaxin expression and secretion by lysophosphatidate and sphingosine 1-phosphate. |
2015 |
J. Lipid Res. |
pmid:25896349
|
Prüfer N et al. |
The role of serum amyloid A and sphingosine-1-phosphate on high-density lipoprotein functionality. |
2015 |
Biol. Chem. |
pmid:25252751
|
Wysoczynski M et al. |
Identification of heme oxygenase 1 (HO-1) as a novel negative regulator of mobilization of hematopoietic stem/progenitor cells. |
2015 |
Stem Cell Rev |
pmid:25086571
|
Czubowicz K et al. |
Sphingosine-1-phosphate and its effect on glucose deprivation/glucose reload stress: from gene expression to neuronal survival. |
2015 |
Mol. Neurobiol. |
pmid:25056275
|
Pan HY et al. |
Sphingosine-1-phosphate mediates AKT/ERK maintenance of dental pulp homoeostasis. |
2015 |
Int Endod J |
pmid:24931601
|
Siow D et al. |
Regulation of de novo sphingolipid biosynthesis by the ORMDL proteins and sphingosine kinase-1. |
2015 |
Adv Biol Regul |
pmid:25319495
|
Sano N et al. |
New drug delivery system for liver sinusoidal endothelial cells for ischemia-reperfusion injury. |
2015 |
World J. Gastroenterol. |
pmid:26668502
|
Iwabuchi K et al. |
Role of Ceramide from Glycosphingolipids and Its Metabolites in Immunological and Inflammatory Responses in Humans. |
2015 |
Mediators Inflamm. |
pmid:26609196
|
Ramos-Perez WD et al. |
A map of the distribution of sphingosine 1-phosphate in the spleen. |
2015 |
Nat. Immunol. |
pmid:26502404
|
Winkler MS et al. |
Decreased serum concentrations of sphingosine-1-phosphate in sepsis. |
2015 |
Crit Care |
pmid:26498205
|
Matula K et al. |
Regulation of cellular sphingosine-1-phosphate by sphingosine kinase 1 and sphingosine-1-phopshate lyase determines chemotherapy resistance in gastroesophageal cancer. |
2015 |
BMC Cancer |
pmid:26493335
|
Barnawi J et al. |
Potential Link between the Sphingosine-1-Phosphate (S1P) System and Defective Alveolar Macrophage Phagocytic Function in Chronic Obstructive Pulmonary Disease (COPD). |
2015 |
PLoS ONE |
pmid:26485657
|
Moruno Manchon JF et al. |
Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy. |
2015 |
Sci Rep |
pmid:26477494
|
Deng Z et al. |
Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis. |
2015 |
Nat Commun |
pmid:25907800
|
Wang K et al. |
Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain. |
2015 |
PLoS Genet. |
pmid:26474409
|
Jeong JK et al. |
Modulation of the expression of sphingosine 1-phosphate 2 receptors regulates the differentiation of pre-adipocytes. |
2015 |
Mol Med Rep |
pmid:26459774
|
Sutter I et al. |
Plasmalogens of high-density lipoproteins (HDL) are associated with coronary artery disease and anti-apoptotic activity of HDL. |
2015 |
Atherosclerosis |
pmid:26093887
|
Kihara Y et al. |
Lysophospholipid receptors in drug discovery. |
2015 |
Exp. Cell Res. |
pmid:25499971
|
Boczkowska-Radziwon B et al. |
Ozonation of human blood increases sphingosine-1-phosphate in plasma. |
2015 |
J. Physiol. Pharmacol. |
pmid:25903957
|
Le Bihan O et al. |
Visualization of adherent cell monolayers by cryo-electron microscopy: A snapshot of endothelial adherens junctions. |
2015 |
J. Struct. Biol. |
pmid:26470813
|
Li C et al. |
Sphingosine 1-phosphate enhances the excitability of rat sensory neurons through activation of sphingosine 1-phosphate receptors 1 and/or 3. |
2015 |
J Neuroinflammation |
pmid:25880547
|
Dai L et al. |
Ceramides promote apoptosis for virus-infected lymphoma cells through induction of ceramide synthases and viral lytic gene expression. |
2015 |
Oncotarget |
pmid:26327294
|
Simón MV et al. |
Sphingosine-1-Phosphate Is a Crucial Signal for Migration of Retina Müller Glial Cells. |
2015 |
Invest. Ophthalmol. Vis. Sci. |
pmid:26325420
|
Yang L et al. |
Sphingosine 1-Phosphate Receptor 2 and 3 Mediate Bone Marrow-Derived Monocyte/Macrophage Motility in Cholestatic Liver Injury in Mice. |
2015 |
Sci Rep |
pmid:26324256
|
Brünnert D et al. |
Sphingosine 1-phosphate regulates IL-8 expression and secretion via S1PR1 and S1PR2 receptors-mediated signaling in extravillous trophoblast derived HTR-8/SVneo cells. |
2015 |
Placenta |
pmid:26321412
|
Zhao YD et al. |
A Biochemical Approach to Understand the Pathogenesis of Advanced Pulmonary Arterial Hypertension: Metabolomic Profiles of Arginine, Sphingosine-1-Phosphate, and Heme of Human Lung. |
2015 |
PLoS ONE |
pmid:26317340
|
Cantalupo A et al. |
Nogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressure. |
2015 |
Nat. Med. |
pmid:26301690
|
Adamiak M et al. |
Evidence for the involvement of sphingosine-1-phosphate in the homing and engraftment of hematopoietic stem cells to bone marrow. |
2015 |
Oncotarget |
pmid:26299919
|
Mori H et al. |
Smad3 deficiency leads to mandibular condyle degradation via the sphingosine 1-phosphate (S1P)/S1P3 signaling axis. |
2015 |
Am. J. Pathol. |
pmid:26272361
|
Camp SM et al. |
Pulmonary endothelial cell barrier enhancement by novel FTY720 analogs: methoxy-FTY720, fluoro-FTY720, and β-glucuronide-FTY720. |
2015 |
Chem. Phys. Lipids |
pmid:26272033
|
Denimal D et al. |
Significant abnormalities of the HDL phosphosphingolipidome in type 1 diabetes despite normal HDL cholesterol concentration. |
2015 |
Atherosclerosis |
pmid:26142685
|
Yagi K et al. |
Therapeutically Targeting Tumor Necrosis Factor-α/Sphingosine-1-Phosphate Signaling Corrects Myogenic Reactivity in Subarachnoid Hemorrhage. |
2015 |
Stroke |
pmid:26138121
|
Nakagawa Y and Chiba K |
Diversity and plasticity of microglial cells in psychiatric and neurological disorders. |
2015 |
Pharmacol. Ther. |
pmid:26129625
|
Jeong SK et al. |
Sphingosine kinase 1 activation enhances epidermal innate immunity through sphingosine-1-phosphate stimulation of cathelicidin production. |
2015 |
J. Dermatol. Sci. |
pmid:26113114
|
Marycz K et al. |
The effect of the bioactive sphingolipids S1P and C1P on multipotent stromal cells--new opportunities in regenerative medicine. |
2015 |
Cell. Mol. Biol. Lett. |
pmid:26110483
|
Chen MH et al. |
Identification of SPHK1 as a therapeutic target and marker of poor prognosis in cholangiocarcinoma. |
2015 |
Oncotarget |
pmid:26090720
|
Panneer Selvam S et al. |
Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. |
2015 |
Sci Signal |
pmid:26082434
|
Malik FA et al. |
Sphingosine-1-Phosphate Is a Novel Regulator of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity. |
2015 |
PLoS ONE |
pmid:26079370
|
Mooren OL et al. |
Role of N-WASP in Endothelial Monolayer Formation and Integrity. |
2015 |
J. Biol. Chem. |
pmid:26070569
|
El-Najjar N et al. |
Increased Levels of Sphingosylphosphorylcholine (SPC) in Plasma of Metabolic Syndrome Patients. |
2015 |
PLoS ONE |
pmid:26466367
|
Hyder CL et al. |
Sphingolipids inhibit vimentin-dependent cell migration. |
2015 |
J. Cell. Sci. |
pmid:25908861
|
Brait VH et al. |
Selective Sphingosine 1-Phosphate Receptor 1 Agonist Is Protective Against Ischemia/Reperfusion in Mice. |
2016 |
Stroke |
pmid:27827329
|
Zamora-Pineda J et al. |
Dendritic cell sphingosine-1-phosphate lyase regulates thymic egress. |
2016 |
J. Exp. Med. |
pmid:27810923
|
Kobayashi N et al. |
Fluorescence-based rapid measurement of sphingosine-1-phosphate transport activity in erythrocytes. |
2016 |
J. Lipid Res. |
pmid:27655910
|
Chew WS et al. |
To fingolimod and beyond: The rich pipeline of drug candidates that target S1P signaling. |
2016 |
Pharmacol. Res. |
pmid:27663260
|
Wang X et al. |
Sphingosine 1-Phosphate Activation of EGFR As a Novel Target for Meningitic Escherichia coli Penetration of the Blood-Brain Barrier. |
2016 |
PLoS Pathog. |
pmid:27711202
|
Poissonnier A et al. |
CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice. |
2016 |
Immunity |
pmid:27438772
|
Zhang Q et al. |
Berberine Preconditioning Protects Neurons Against Ischemia via Sphingosine-1-Phosphate and Hypoxia-Inducible Factor-1[Formula: see text]. |
2016 |
Am. J. Chin. Med. |
pmid:27430910
|
Adamiak M et al. |
Downregulation of Heme Oxygenase 1 (HO-1) Activity in Hematopoietic Cells Enhances Their Engraftment After Transplantation. |
2016 |
Cell Transplant |
pmid:27412411
|
Fleming JK et al. |
A novel approach for measuring sphingosine-1-phosphate and lysophosphatidic acid binding to carrier proteins using monoclonal antibodies and the Kinetic Exclusion Assay. |
2016 |
J. Lipid Res. |
pmid:27444045
|
Tong S et al. |
Structural Insight into Substrate Selection and Catalysis of Lipid Phosphate Phosphatase PgpB in the Cell Membrane. |
2016 |
J. Biol. Chem. |
pmid:27405756
|
Nagura Y et al. |
Regulation of the lysophosphatidylserine and sphingosine 1-phosphate levels in autologous whole blood by the pre-storage leukocyte reduction. |
2016 |
Transfus Med |
pmid:27350440
|
Crespo I et al. |
Melatonin inhibits the sphingosine kinase 1/sphingosine-1-phosphate signaling pathway in rabbits with fulminant hepatitis of viral origin. |
2016 |
J. Pineal Res. |
pmid:27101794
|
Riganti L et al. |
Sphingosine-1-Phosphate (S1P) Impacts Presynaptic Functions by Regulating Synapsin I Localization in the Presynaptic Compartment. |
2016 |
J. Neurosci. |
pmid:27098703
|
Cai Y et al. |
FOXF1 maintains endothelial barrier function and prevents edema after lung injury. |
2016 |
Sci Signal |
pmid:27095594
|
Castaldi A et al. |
Sphingosine 1-phosphate elicits RhoA-dependent proliferation and MRTF-A mediated gene induction in CPCs. |
2016 |
Cell. Signal. |
pmid:27094722
|
Anbazhagan AN et al. |
Transcriptional modulation of SLC26A3 (DRA) by sphingosine-1-phosphate. |
2016 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:27079615
|
Trinh HK et al. |
Exploration of the Sphingolipid Metabolite, Sphingosine-1-phosphate and Sphingosine, as Novel Biomarkers for Aspirin-exacerbated Respiratory Disease. |
2016 |
Sci Rep |
pmid:27830727
|
Zhang H et al. |
Binding Characteristics of Sphingosine-1-Phosphate to ApoM hints to Assisted Release Mechanism via the ApoM Calyx-Opening. |
2016 |
Sci Rep |
pmid:27476912
|
Li J et al. |
Overexpression of SphK1 enhances cell proliferation and invasion in triple-negative breast cancer via the PI3K/AKT signaling pathway. |
2016 |
Tumour Biol. |
pmid:26857281
|
Camaré C et al. |
The neutral sphingomyelinase-2 is involved in angiogenic signaling triggered by oxidized LDL. |
2016 |
Free Radic. Biol. Med. |
pmid:26855418
|
Kim SE et al. |
The Role of Sphingosine-1-Phosphate in Adipogenesis of Graves' Orbitopathy. |
2016 |
Invest. Ophthalmol. Vis. Sci. |
pmid:26830367
|
Messias CV et al. |
Sphingosine-1-Phosphate Induces Dose-Dependent Chemotaxis or Fugetaxis of T-ALL Blasts through S1P1 Activation. |
2016 |
PLoS ONE |
pmid:26824863
|
Pászti-Gere E et al. |
Reinforced Epithelial Barrier Integrity via Matriptase Induction with Sphingosine-1-Phosphate Did Not Result in Disturbances in Physiological Redox Status. |
2016 |
Oxid Med Cell Longev |
pmid:26823955
|
Maczis M et al. |
Sphingosine-1-phosphate and estrogen signaling in breast cancer. |
2016 |
Adv Biol Regul |
pmid:26601898
|
Zhang F et al. |
Sphingosine 1-phosphate signaling contributes to cardiac inflammation, dysfunction, and remodeling following myocardial infarction. |
2016 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:26589326
|
Pyne NJ and Tigyi GJ |
A reflection of the lasting contributions from Dr. Robert Bittman to sterol trafficking, sphingolipid and phospholipid research. |
2016 |
Prog. Lipid Res. |
pmid:26584871
|
Rana A and Sharma S |
Mechanism of sphingosine-1-phosphate induced cardioprotection against I/R injury in diabetic rat heart: Possible involvement of glycogen synthase kinase 3β and mitochondrial permeability transition pore. |
2016 |
Clin. Exp. Pharmacol. Physiol. |
pmid:26582369
|
Nagahashi M et al. |
Interstitial Fluid Sphingosine-1-Phosphate in Murine Mammary Gland and Cancer and Human Breast Tissue and Cancer Determined by Novel Methods. |
2016 |
J Mammary Gland Biol Neoplasia |
pmid:27194029
|
Patmanathan SN et al. |
Aberrant expression of the S1P regulating enzymes, SPHK1 and SGPL1, contributes to a migratory phenotype in OSCC mediated through S1PR2. |
2016 |
Sci Rep |
pmid:27160553
|
Li N and Zhang F |
Implication of sphingosin-1-phosphate in cardiovascular regulation. |
2016 |
Front Biosci (Landmark Ed) |
pmid:27100508
|
Zhang L et al. |
Sphingosine-1-phosphate Maintains Normal Vascular Permeability by Preserving Endothelial Surface Glycocalyx in Intact Microvessels. |
2016 |
Microcirculation |
pmid:27015105
|
Kurano M et al. |
Resveratrol exerts a biphasic effect on apolipoprotein M. |
2016 |
Br. J. Pharmacol. |
pmid:26445217
|