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Sphingosine-1-phosphate improves endothelialization with reduction of thrombosis in recellularized human umbilical vein graft by inhibiting syndecan-1 shedding in vitro. |
2017 |
Acta Biomater |
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Metastatic triple-negative breast cancer is dependent on SphKs/S1P signaling for growth and survival. |
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Cell. Signal. |
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Sphingosine-1-phosphate signalling-a key player in the pathogenesis of Angiotensin II-induced hypertension. |
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Cardiovasc. Res. |
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Atkinson D et al. |
Sphingosine 1-phosphate lyase deficiency causes Charcot-Marie-Tooth neuropathy. |
2017 |
Neurology |
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The role of sphingolipid signalling in diabetes‑associated pathologies (Review). |
2017 |
Int. J. Mol. Med. |
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High-density lipoprotein-associated sphingosine-1-phosphate activity in heterozygous familial hypercholesterolaemia. |
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Eur. J. Clin. Invest. |
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Gradients of the signaling lipid S1P in lymph nodes position natural killer cells and regulate their interferon-γ response. |
2017 |
Nat. Immunol. |
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Hepatic Stellate Cell Selective Disruption of Dynamin-2 GTPase Increases Murine Fibrogenesis through Up-Regulation of Sphingosine-1 Phosphate-Induced Cell Migration. |
2017 |
Am. J. Pathol. |
pmid:27840081
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Sphingosine-1-phosphate receptor therapies: Advances in clinical trials for CNS-related diseases. |
2017 |
Neuropharmacology |
pmid:27825807
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Engel N et al. |
Synergistic Action of Genistein and Calcitriol in Immature Osteosarcoma MG-63 Cells by SGPL1 Up-Regulation. |
2017 |
PLoS ONE |
pmid:28125641
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Yanagida K and Hla T |
Vascular and Immunobiology of the Circulatory Sphingosine 1-Phosphate Gradient. |
2017 |
Annu. Rev. Physiol. |
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A phase 2 study of the sphingosine-1-phosphate antibody sonepcizumab in patients with metastatic renal cell carcinoma. |
2017 |
Cancer |
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Valproic acid enforces the priming effect of sphingosine-1 phosphate on human mesenchymal stem cells. |
2017 |
Int. J. Mol. Med. |
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Therapeutic Strategies and Pharmacological Tools Influencing S1P Signaling and Metabolism. |
2017 |
Med Res Rev |
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Sphingosine-1-phosphate suppresses chondrosarcoma metastasis by upregulation of tissue inhibitor of metalloproteinase 3 through suppressing miR-101 expression. |
2017 |
Mol Oncol |
pmid:28672103
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Targeting sphingosine-1-phosphate signaling for cancer therapy. |
2017 |
Sci China Life Sci |
pmid:28623546
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Size-selective opening of the blood-brain barrier by targeting endothelial sphingosine 1-phosphate receptor 1. |
2017 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:28396408
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Vehicle-dependent Effects of Sphingosine 1-phosphate on Plasminogen Activator Inhibitor-1 Expression. |
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J. Atheroscler. Thromb. |
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Vitamin D protects against Aβ peptide cytotoxicity in differentiated human neuroblastoma SH- SY5Y cells: A role for S1P1/p38MAPK/ATF4 axis. |
2017 |
Neuropharmacology |
pmid:28077289
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Leo A et al. |
The Sphingosine 1-Phosphate Signaling Pathway in Epilepsy: A Possible Role for the Immunomodulator Drug Fingolimod in Epilepsy Treatment. |
2017 |
CNS Neurol Disord Drug Targets |
pmid:27823573
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Roch L et al. |
High-Resolution Expression Profiling of Peripheral Blood CD8 Cells in Patients with Multiple Sclerosis Displays Fingolimod-Induced Immune Cell Redistribution. |
2017 |
Mol. Neurobiol. |
pmid:27631876
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Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets. |
2017 |
Nature |
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Reinhard NR et al. |
The balance between Gα-Cdc42/Rac and Gα/-RhoA pathways determines endothelial barrier regulation by sphingosine-1-phosphate. |
2017 |
Mol. Biol. Cell |
pmid:28954861
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Natarajan V et al. |
Expression profiling of genes regulated by sphingosine kinase1 signaling in a murine model of hyperoxia induced neonatal bronchopulmonary dysplasia. |
2017 |
BMC Genomics |
pmid:28851267
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Hajny S and Christoffersen C |
A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation. |
2017 |
Int J Mol Sci |
pmid:28749426
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Bertlich M et al. |
Fingolimod (FTY-720) is Capable of Reversing Tumor Necrosis Factor Induced Decreases in Cochlear Blood Flow. |
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Otol. Neurotol. |
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Koch A et al. |
Vitamin D Supplementation Enhances C18(dihydro)ceramide Levels in Type 2 Diabetes Patients. |
2017 |
Int J Mol Sci |
pmid:28714882
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Angiogenesis Model of Cornea to Understand the Role of Sphingosine 1-Phosphate. |
2017 |
Methods Mol. Biol. |
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Epigenetic regulation of pro-inflammatory cytokine secretion by sphingosine 1-phosphate (S1P) in acute lung injury: Role of S1P lyase. |
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Adv Biol Regul |
pmid:27720306
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Al-Jarallah A and Oriowo M |
The effect of sphingosine-1-phosphate on colonic smooth muscle contractility: Modulation by TNBS-induced colitis. |
2017 |
PLoS ONE |
pmid:28493876
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Sphingosine-1-phosphate modulators in inflammatory skin diseases - lining up for clinical translation. |
2017 |
Exp. Dermatol. |
pmid:27574180
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HuR mediates motility of human bone marrow-derived mesenchymal stem cells triggered by sphingosine 1-phosphate in liver fibrosis. |
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J. Mol. Med. |
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Epithelial cell extrusion: Pathways and pathologies. |
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Semin. Cell Dev. Biol. |
pmid:27212253
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Automated tracking and quantification of angiogenic vessel formation in 3D microfluidic devices. |
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PLoS ONE |
pmid:29136008
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Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD. |
2017 |
PLoS ONE |
pmid:29112690
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Sphingosine-1-Phosphate Mediates Fibrosis in Orbital Fibroblasts in Graves' Orbitopathy. |
2017 |
Invest. Ophthalmol. Vis. Sci. |
pmid:28492873
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Sphingosine-1-Phosphate (S1P)-Related Response of Human Conjunctival Fibroblasts After Filtration Surgery for Glaucoma. |
2017 |
Invest. Ophthalmol. Vis. Sci. |
pmid:28418499
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A Shift in ApoM/S1P Between HDL-Particles in Women With Type 1 Diabetes Mellitus Is Associated With Impaired Anti-Inflammatory Effects of the ApoM/S1P Complex. |
2017 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:28385702
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The role of sphingosine-1-phosphate in the tumor microenvironment and its clinical implications. |
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Tumour Biol. |
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Sphingolipids metabolism in the salivary glands of rats with obesity and streptozotocin induced diabetes. |
2017 |
J. Cell. Physiol. |
pmid:28369933
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Ageing adversely affects the migration and function of marginal zone B cells. |
2017 |
Immunology |
pmid:28369800
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Müller J et al. |
Differential S1P Receptor Profiles on M1- and M2-Polarized Macrophages Affect Macrophage Cytokine Production and Migration. |
2017 |
Biomed Res Int |
pmid:28367448
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Sphingosine-1-Phosphate Prevents Egress of Hematopoietic Stem Cells From Liver to Reduce Fibrosis. |
2017 |
Gastroenterology |
pmid:28363640
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Sphingosine-1-Phosphate Metabolism and Its Role in the Development of Inflammatory Bowel Disease. |
2017 |
Int J Mol Sci |
pmid:28362332
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Mildly oxidized HDL decrease agonist-induced platelet aggregation and release of pro-coagulant platelet extracellular vesicles. |
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J. Steroid Biochem. Mol. Biol. |
pmid:27163393
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Shear stress induces Gα activation independently of G protein-coupled receptor activation in endothelial cells. |
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Am. J. Physiol., Cell Physiol. |
pmid:28148497
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The effects of graded levels of calorie restriction: IX. Global metabolomic screen reveals modulation of carnitines, sphingolipids and bile acids in the liver of C57BL/6 mice. |
2017 |
Aging Cell |
pmid:28139067
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Altered Expression of Sphingosine-1-Phosphate Metabolizing Enzymes in Oral Cancer Correlate With Clinicopathological Attributes. |
2017 |
Cancer Invest. |
pmid:28135860
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Kurano M et al. |
Involvement of CETP (Cholesteryl Ester Transfer Protein) in the Shift of Sphingosine-1-Phosphate Among Lipoproteins and in the Modulation of its Functions. |
2017 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:28126827
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Wang Y et al. |
The role of sphingosine 1-phosphate receptor 2 in bile-acid-induced cholangiocyte proliferation and cholestasis-induced liver injury in mice. |
2017 |
Hepatology |
pmid:28120434
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