Fu P et al. |
Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium. |
2016 |
J. Biol. Chem. |
pmid:27864331
|
Adamiak M et al. |
The Involvment of Hematopoietic-Specific PLC -β2 in Homing and Engraftment of Hematopoietic Stem/Progenitor Cells. |
2016 |
Stem Cell Rev |
pmid:27704316
|
Morillon YM et al. |
Antibody Binding to CD4 Induces Rac GTPase Activation and Alters T Cell Migration. |
2016 |
J. Immunol. |
pmid:27694496
|
Liu X et al. |
ApoA-I induces S1P release from endothelial cells through ABCA1 and SR-BI in a positive feedback manner. |
2016 |
J. Physiol. Biochem. |
pmid:27377933
|
Egom EE et al. |
Effect of sphingosine-1-phosphate on L-type calcium current and Ca(2+) transient in rat ventricular myocytes. |
2016 |
Mol. Cell. Biochem. |
pmid:27372350
|
Sanagawa A et al. |
Sphingosine 1‑phosphate induced by hypoxia increases the expression of PAI‑1 in HepG2 cells via HIF‑1α. |
2016 |
Mol Med Rep |
pmid:27357063
|
Tiper IV et al. |
Sphingosine 1-phosphate signaling impacts lymphocyte migration, inflammation and infection. |
2016 |
Pathog Dis |
pmid:27354294
|
Jung M et al. |
Lipocalin 2 from macrophages stimulated by tumor cell-derived sphingosine 1-phosphate promotes lymphangiogenesis and tumor metastasis. |
2016 |
Sci Signal |
pmid:27353364
|
Koresawa R et al. |
Sphingosine-1-phosphate receptor 1 as a prognostic biomarker and therapeutic target for patients with primary testicular diffuse large B-cell lymphoma. |
2016 |
Br. J. Haematol. |
pmid:27061580
|
Resop RS et al. |
Sphingosine-1-phosphate/sphingosine-1-phosphate receptor 1 signaling is required for migration of naive human TÂ cells from the thymus to the periphery. |
2016 |
J. Allergy Clin. Immunol. |
pmid:27056271
|
Guo J et al. |
Identification and synthesis of potent and selective pyridyl-isoxazole based agonists of sphingosine-1-phosphate 1 (S1P1). |
2016 |
Bioorg. Med. Chem. Lett. |
pmid:27055941
|
Adams DR et al. |
Sphingosine Kinases: Emerging Structure-Function Insights. |
2016 |
Trends Biochem. Sci. |
pmid:27021309
|
Lv M et al. |
Sphingosine kinase 1/sphingosine-1-phosphate regulates the expression of interleukin-17A in activated microglia in cerebral ischemia/reperfusion. |
2016 |
Inflamm. Res. |
pmid:27002656
|
Wang H et al. |
Potential serum biomarkers from a metabolomics study of autism. |
2016 |
J Psychiatry Neurosci |
pmid:26395811
|
Farez MF and Correale J |
Sphingosine 1-phosphate signaling in astrocytes: Implications for progressive multiple sclerosis. |
2016 |
J. Neurol. Sci. |
pmid:26810518
|
Santos-Cortez RL et al. |
Autosomal-Recessive Hearing Impairment Due to Rare Missense Variants within S1PR2. |
2016 |
Am. J. Hum. Genet. |
pmid:26805784
|
Bock S et al. |
Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells. |
2016 |
J. Dermatol. Sci. |
pmid:26803226
|
Marycz K et al. |
The influence of metal-based biomaterials functionalized with sphingosine-1-phosphate on the cellular response and osteogenic differentaion potenial of human adipose derived mesenchymal stem cells in vitro. |
2016 |
J Biomater Appl |
pmid:26801473
|
Yuasa D et al. |
C1q/TNF-related protein-1 functions to protect against acute ischemic injury in the heart. |
2016 |
FASEB J. |
pmid:26578687
|
Ratajczak MZ and Suszynska M |
Emerging Strategies to Enhance Homing and Engraftment of Hematopoietic Stem Cells. |
2016 |
Stem Cell Rev |
pmid:26400757
|
Yaghobian D et al. |
Increased sphingosine 1-phosphate mediates inflammation and fibrosis in tubular injury in diabetic nephropathy. |
2016 |
Clin. Exp. Pharmacol. Physiol. |
pmid:26414003
|
Bae SJ et al. |
The circulating sphingosine-1-phosphate level predicts incident fracture in postmenopausal women: a 3.5-year follow-up observation study. |
2016 |
Osteoporos Int |
pmid:26984570
|
Kalhori V et al. |
FTY720 (Fingolimod) attenuates basal and sphingosine-1-phosphate-evoked thyroid cancer cell invasion. |
2016 |
Endocr. Relat. Cancer |
pmid:26935838
|
Setoguchi R |
IL-15 boosts the function and migration of human terminally differentiated CD8+ T cells by inducing a unique gene signature. |
2016 |
Int. Immunol. |
pmid:26857736
|
Nojima H et al. |
Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate. |
2016 |
J. Hepatol. |
pmid:26254847
|
Kim BJ et al. |
The effect of sphingosine-1-phosphate on bone metabolism in humans depends on its plasma/bone marrow gradient. |
2016 |
J. Endocrinol. Invest. |
pmid:26219613
|
Touat-Hamici Z et al. |
Role of lipid phosphate phosphatase 3 in human aortic endothelial cell function. |
2016 |
Cardiovasc. Res. |
pmid:27694435
|
Medina CB and Ravichandran KS |
Do not let death do us part: 'find-me' signals in communication between dying cells and the phagocytes. |
2016 |
Cell Death Differ. |
pmid:26891690
|
Japtok L et al. |
Sphingosine 1-phosphate counteracts insulin signaling in pancreatic β-cells via the sphingosine 1-phosphate receptor subtype 2. |
2015 |
FASEB J. |
pmid:25911610
|
Stone ML et al. |
Sphingosine-1-phosphate receptor 1 agonism attenuates lung ischemia-reperfusion injury. |
2015 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:25910934
|
Desai P et al. |
Dyslipidemia regulates thrombospondin-1-induced vascular smooth muscle cell chemotaxis. |
2015 |
Mol. Cell. Biochem. |
pmid:26350564
|
Riley RT et al. |
A blood spot method for detecting fumonisin-induced changes in putative sphingolipid biomarkers in LM/Bc mice and humans. |
2015 |
Food Addit Contam Part A Chem Anal Control Expo Risk Assess |
pmid:25833119
|
Proia RL and Hla T |
Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy. |
2015 |
J. Clin. Invest. |
pmid:25831442
|
Lee SY et al. |
Activation of sphingosine kinase 2 by endoplasmic reticulum stress ameliorates hepatic steatosis and insulin resistance in mice. |
2015 |
Hepatology |
pmid:25808625
|
Salama MF et al. |
A novel role of sphingosine kinase-1 in the invasion and angiogenesis of VHL mutant clear cell renal cell carcinoma. |
2015 |
FASEB J. |
pmid:25805832
|
Potì F et al. |
SKI-II--a sphingosine kinase 1 inhibitor--exacerbates atherosclerosis in low-density lipoprotein receptor-deficient (LDL-R-/-) mice on high cholesterol diet. |
2015 |
Atherosclerosis |
pmid:25801013
|
Castillo-Badillo JA et al. |
α1B-adrenergic receptors differentially associate with Rab proteins during homologous and heterologous desensitization. |
2015 |
PLoS ONE |
pmid:25799564
|
Brulhart-Meynet MC et al. |
Improving reconstituted HDL composition for efficient post-ischemic reduction of ischemia reperfusion injury. |
2015 |
PLoS ONE |
pmid:25781943
|
Nojima H et al. |
Sphingolipids in liver injury, repair and regeneration. |
2015 |
Biol. Chem. |
pmid:25781682
|
Newton J et al. |
Revisiting the sphingolipid rheostat: Evolving concepts in cancer therapy. |
2015 |
Exp. Cell Res. |
pmid:25770011
|
Muñoz-Sáez E et al. |
Neuroprotective role of sphingosine-1-phosphate in L-BMAA treated neuroblastoma cells (SH-SY5Y). |
2015 |
Neurosci. Lett. |
pmid:25769802
|
Kang H et al. |
The Therapeutic Effects of Human Mesenchymal Stem Cells Primed with Sphingosine-1 Phosphate on Pulmonary Artery Hypertension. |
2015 |
Stem Cells Dev. |
pmid:25761906
|
Chen LY et al. |
The Arabidopsis alkaline ceramidase TOD1 is a key turgor pressure regulator in plant cells. |
2015 |
Nat Commun |
pmid:25591940
|
Zhang L et al. |
Anti-S1P Antibody as a Novel Therapeutic Strategy for VEGFR TKI-Resistant Renal Cancer. |
2015 |
Clin. Cancer Res. |
pmid:25589614
|
Chavez A et al. |
S1PR1 Tyr143 phosphorylation downregulates endothelial cell surface S1PR1 expression and responsiveness. |
2015 |
J. Cell. Sci. |
pmid:25588843
|
O'Sullivan C and Dev KK |
Galactosylsphingosine (psychosine)-induced demyelination is attenuated by sphingosine 1-phosphate signalling. |
2015 |
J. Cell. Sci. |
pmid:26359302
|
Woszczek G and Fuerst E |
Ca2+ mobilization assays in GPCR drug discovery. |
2015 |
Methods Mol. Biol. |
pmid:25563178
|
Li Q et al. |
Differential activation of receptors and signal pathways upon stimulation by different doses of sphingosine-1-phosphate in endothelial cells. |
2015 |
Exp. Physiol. |
pmid:25557733
|
Borup A et al. |
Apolipoprotein M in lipid metabolism and cardiometabolic diseases. |
2015 |
Curr. Opin. Lipidol. |
pmid:25551802
|
Montecucco F et al. |
Impact of systemic inflammation and autoimmune diseases on apoA-I and HDL plasma levels and functions. |
2015 |
Handb Exp Pharmacol |
pmid:25522998
|
Nofer JR |
Signal transduction by HDL: agonists, receptors, and signaling cascades. |
2015 |
Handb Exp Pharmacol |
pmid:25522990
|
Baranowski M et al. |
Exercise increases sphingoid base-1-phosphate levels in human blood and skeletal muscle in a time- and intensity-dependent manner. |
2015 |
Eur. J. Appl. Physiol. |
pmid:25519954
|
Oskeritzian CA et al. |
The sphingosine-1-phosphate/sphingosine-1-phosphate receptor 2 axis regulates early airway T-cell infiltration in murine mast cell-dependent acute allergic responses. |
2015 |
J. Allergy Clin. Immunol. |
pmid:25512083
|
Kurano M et al. |
LDL receptor and ApoE are involved in the clearance of ApoM-associated sphingosine 1-phosphate. |
2015 |
J. Biol. Chem. |
pmid:25505264
|
Moon MH et al. |
Activation of S1P2 receptor, a possible mechanism of inhibition of adipogenic differentiation by sphingosine 1‑phosphate. |
2015 |
Mol Med Rep |
pmid:25351259
|
Klocke S et al. |
Slow-freezing versus vitrification for human ovarian tissue cryopreservation. |
2015 |
Arch. Gynecol. Obstet. |
pmid:25115279
|
Sar JI et al. |
Sphingosine-1-phosphate stimulated connective tissue growth factor expression in human buccal fibroblasts: Inhibition by epigallocatechin-3-gallate. |
2015 |
J. Formos. Med. Assoc. |
pmid:24035571
|
Zhang T et al. |
Apigenin attenuates heart injury in lipopolysaccharide-induced endotoxemic model by suppressing sphingosine kinase 1/sphingosine 1-phosphate signaling pathway. |
2015 |
Chem. Biol. Interact. |
pmid:25557508
|
Burow P et al. |
Activation of ATP secretion via volume-regulated anion channels by sphingosine-1-phosphate in RAW macrophages. |
2015 |
Pflugers Arch. |
pmid:24965069
|
Pan HY et al. |
Sphingosine-1-phosphate mediates AKT/ERK maintenance of dental pulp homoeostasis. |
2015 |
Int Endod J |
pmid:24931601
|
Siow D et al. |
Regulation of de novo sphingolipid biosynthesis by the ORMDL proteins and sphingosine kinase-1. |
2015 |
Adv Biol Regul |
pmid:25319495
|
Kurek K et al. |
Inhibition of Ceramide De Novo Synthesis Ameliorates Diet Induced Skeletal Muscles Insulin Resistance. |
2015 |
J Diabetes Res |
pmid:26380311
|
Zhao C et al. |
Chemical Hypoxia Brings to Light Altered Autocrine Sphingosine-1-Phosphate Signalling in Rheumatoid Arthritis Synovial Fibroblasts. |
2015 |
Mediators Inflamm. |
pmid:26556954
|
Wang Z et al. |
Decreased Splenic CD4(+) T-Lymphocytes in Apolipoprotein M Gene Deficient Mice. |
2015 |
Biomed Res Int |
pmid:26543853
|
Yu H et al. |
Effect of sphingosine-1-phosphate and myoblast transplantation on rat acute myocardial infarction. |
2015 |
Genet. Mol. Res. |
pmid:26535699
|
Wang R et al. |
Exosome Adherence and Internalization by Hepatic Stellate Cells Triggers Sphingosine 1-Phosphate-dependent Migration. |
2015 |
J. Biol. Chem. |
pmid:26534962
|
Fujii S |
[Atherosclerosis, Chronic Inflammation, and Thrombosis: In Search of the Missing Link in Laboratory Medicine]. |
2015 |
Rinsho Byori |
pmid:26524900
|
Jones EE et al. |
Tissue biomarkers of drug efficacy: case studies using a MALDI-MSI workflow. |
2015 |
Bioanalysis |
pmid:26505686
|
Ramos-Perez WD et al. |
A map of the distribution of sphingosine 1-phosphate in the spleen. |
2015 |
Nat. Immunol. |
pmid:26502404
|
Winkler MS et al. |
Decreased serum concentrations of sphingosine-1-phosphate in sepsis. |
2015 |
Crit Care |
pmid:26498205
|
Scanlon KM et al. |
Novel therapies for the treatment of pertussis disease. |
2015 |
Pathog Dis |
pmid:26394802
|
Frej C et al. |
Quantification of sphingosine 1-phosphate by validated LC-MS/MS method revealing strong correlation with apolipoprotein M in plasma but not in serum due to platelet activation during blood coagulation. |
2015 |
Anal Bioanal Chem |
pmid:26377937
|
Klyachkin YM et al. |
Pharmacological Elevation of Circulating Bioactive Phosphosphingolipids Enhances Myocardial Recovery After Acute Infarction. |
2015 |
Stem Cells Transl Med |
pmid:26371341
|
Zeng Y et al. |
Sphingosine 1-phosphate induced synthesis of glycocalyx on endothelial cells. |
2015 |
Exp. Cell Res. |
pmid:26364737
|
Choi S et al. |
A genetic variant of cortactin linked to acute lung injury impairs lamellipodia dynamics and endothelial wound healing. |
2015 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:26361873
|
Flávia Nardy A et al. |
Modulation of Intrathymic Sphingosine-1-Phosphate Levels Promotes Escape of Immature Thymocytes to the Periphery with a Potential Proinflammatory Role in Chagas Disease. |
2015 |
Biomed Res Int |
pmid:26347020
|
Dai L et al. |
Ceramides promote apoptosis for virus-infected lymphoma cells through induction of ceramide synthases and viral lytic gene expression. |
2015 |
Oncotarget |
pmid:26327294
|
Simón MV et al. |
Sphingosine-1-Phosphate Is a Crucial Signal for Migration of Retina Müller Glial Cells. |
2015 |
Invest. Ophthalmol. Vis. Sci. |
pmid:26325420
|
Hsu CK et al. |
Mevastatin ameliorates sphingosine 1-phosphate-induced COX-2/PGE2-dependent cell migration via FoxO1 and CREB phosphorylation and translocation. |
2015 |
Br. J. Pharmacol. |
pmid:26359950
|
Adada MM et al. |
Intracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion. |
2015 |
FASEB J. |
pmid:26209696
|
Wang H et al. |
Sphingosine-1-Phosphate Induces the Migration and Angiogenesis of Epcs Through the Akt Signaling Pathway via Sphingosine-1-Phosphate Receptor 3/Platelet-Derived Growth Factor Receptor-β. |
2015 |
Cell. Mol. Biol. Lett. |
pmid:26208383
|
Manes NP et al. |
Targeted Proteomics-Driven Computational Modeling of Macrophage S1P Chemosensing. |
2015 |
Mol. Cell Proteomics |
pmid:26199343
|
Spampinato SF et al. |
Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli? |
2015 |
PLoS ONE |
pmid:26197437
|
Airola MV et al. |
Structural Basis for Ceramide Recognition and Hydrolysis by Human Neutral Ceramidase. |
2015 |
Structure |
pmid:26190575
|
Vettorazzi S et al. |
Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1. |
2015 |
Nat Commun |
pmid:26183376
|
Michels M et al. |
Decreased plasma levels of the endothelial protective sphingosine-1-phosphate are associated with dengue-induced plasma leakage. |
2015 |
J. Infect. |
pmid:26183296
|
Checa A et al. |
Circulating levels of sphingosine-1-phosphate are elevated in severe, but not mild psoriasis and are unresponsive to anti-TNF-α treatment. |
2015 |
Sci Rep |
pmid:26174087
|
Schaffert SA et al. |
mir-181a-1/b-1 Modulates Tolerance through Opposing Activities in Selection and Peripheral T Cell Function. |
2015 |
J. Immunol. |
pmid:26163591
|
Gao Y et al. |
Sphingosine kinase 1 as an anticancer therapeutic target. |
2015 |
Drug Des Devel Ther |
pmid:26150697
|
Denimal D et al. |
Significant abnormalities of the HDL phosphosphingolipidome in type 1 diabetes despite normal HDL cholesterol concentration. |
2015 |
Atherosclerosis |
pmid:26142685
|
Yagi K et al. |
Therapeutically Targeting Tumor Necrosis Factor-α/Sphingosine-1-Phosphate Signaling Corrects Myogenic Reactivity in Subarachnoid Hemorrhage. |
2015 |
Stroke |
pmid:26138121
|
Morad SA and Cabot MC |
Tamoxifen regulation of sphingolipid metabolism--Therapeutic implications. |
2015 |
Biochim. Biophys. Acta |
pmid:25964209
|
Jing XD et al. |
The relationship between the high-density lipoprotein (HDL)-associated sphingosine-1-phosphate (S1P) and coronary in-stent restenosis. |
2015 |
Clin. Chim. Acta |
pmid:25958848
|
Laurenzana A et al. |
Endothelial sphingosine kinase/SPNS2 axis is critical for vessel-like formation by human mesoangioblasts. |
2015 |
J. Mol. Med. |
pmid:25952146
|
Rahman MM et al. |
Secretion of PDGF isoforms during osteoclastogenesis and its modulation by anti-osteoclast drugs. |
2015 |
Biochem. Biophys. Res. Commun. |
pmid:25951977
|
Prager B et al. |
Sphingosine 1-phosphate signaling at the blood-brain barrier. |
2015 |
Trends Mol Med |
pmid:25939882
|
Rosenberg AJ et al. |
A practical process for the preparation of [(32)P]S1P and binding assay for S1P receptor ligands. |
2015 |
Appl Radiat Isot |
pmid:25931137
|
Trayssac M et al. |
Role of Sphingosine-1-Phosphate in Transplant Vasculopathy Evoked by Anti-HLA Antibody. |
2015 |
Am. J. Transplant. |
pmid:25930666
|
Pulkoski-Gross MJ et al. |
Sphingosine-1-phosphate metabolism: A structural perspective. |
2015 |
Crit. Rev. Biochem. Mol. Biol. |
pmid:25923252
|
Ader I et al. |
Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer. |
2015 |
Oncotarget |
pmid:25915662
|