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Genes Cells |
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Immunobiology |
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Low- and high-density lipoproteins modulate function, apoptosis, and proliferation of primary human and murine pancreatic beta-cells. |
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Endocrinology |
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2009 |
Naunyn Schmiedebergs Arch. Pharmacol. |
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Hypoxic preconditioning-induced cerebral ischemic tolerance: role of microvascular sphingosine kinase 2. |
2009 |
Stroke |
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Local effects of the sphingosine 1-phosphate on prostaglandin F2alpha-induced luteolysis in the pregnant rat. |
2009 |
Mol. Reprod. Dev. |
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Sphingosine 1-phosphate is an important endogenous cardioprotectant released by ischemic pre- and postconditioning. |
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Transforming growth factor-beta2 upregulates sphingosine kinase-1 activity, which in turn attenuates the fibrotic response to TGF-beta2 by impeding CTGF expression. |
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Kidney Int. |
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Sphingosine 1-phosphate increases glucose uptake through trans-activation of insulin receptor. |
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J. Allergy Clin. Immunol. |
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Bone marrow progenitor cells induce endothelial adherens junction integrity by sphingosine-1-phosphate-mediated Rac1 and Cdc42 signaling. |
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[Molecular target drug development for curing multiple sclerosis]. |
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Brain Nerve |
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Native and reconstituted HDL protect cardiomyocytes from doxorubicin-induced apoptosis. |
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Normalization of diabetic wound healing. |
2010 |
Surgery |
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Transforming growth factor-beta1 downregulates caveolin-1 expression and enhances sphingosine 1-phosphate signaling in cultured vascular endothelial cells. |
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Am. J. Physiol., Cell Physiol. |
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Sphingosine-1-phosphate effects on the inner wall of Schlemm's canal and outflow facility in perfused human eyes. |
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The immunomodulatory sphingosine 1-phosphate analog FTY720 reduces lesion size and improves neurological outcome in a mouse model of cerebral ischemia. |
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Plasma sphingosine-1-phosphate concentration is reduced in patients with myocardial infarction. |
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