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Introduction to the ECR special issue on lysophospholipids in biology. |
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Exp. Cell Res. |
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Sphingosine-1-phosphate induces the migration of thyroid follicular carcinoma cells through the microRNA-17/PTK6/ERK1/2 pathway. |
2015 |
PLoS ONE |
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Growth factors mediated differentiation of mesenchymal stem cells to cardiac polymicrotissue using hanging drop and bioreactor. |
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Cell Biol. Int. |
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The life and work of Dr. Robert Bittman (1942-2014). |
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Biol. Chem. |
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New drug delivery system for liver sinusoidal endothelial cells for ischemia-reperfusion injury. |
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World J. Gastroenterol. |
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Potential Link between the Sphingosine-1-Phosphate (S1P) System and Defective Alveolar Macrophage Phagocytic Function in Chronic Obstructive Pulmonary Disease (COPD). |
2015 |
PLoS ONE |
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Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy. |
2015 |
Sci Rep |
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Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis. |
2015 |
Nat Commun |
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Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain. |
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Ozonation of human blood increases sphingosine-1-phosphate in plasma. |
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Sphingosine 1-Phosphate Receptor 2 and 3 Mediate Bone Marrow-Derived Monocyte/Macrophage Motility in Cholestatic Liver Injury in Mice. |
2015 |
Sci Rep |
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Sphingosine 1-phosphate regulates IL-8 expression and secretion via S1PR1 and S1PR2 receptors-mediated signaling in extravillous trophoblast derived HTR-8/SVneo cells. |
2015 |
Placenta |
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A Biochemical Approach to Understand the Pathogenesis of Advanced Pulmonary Arterial Hypertension: Metabolomic Profiles of Arginine, Sphingosine-1-Phosphate, and Heme of Human Lung. |
2015 |
PLoS ONE |
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Sphingosine kinase 1 activation enhances epidermal innate immunity through sphingosine-1-phosphate stimulation of cathelicidin production. |
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The effect of the bioactive sphingolipids S1P and C1P on multipotent stromal cells--new opportunities in regenerative medicine. |
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Cell. Mol. Biol. Lett. |
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Bioactive lysophospholipids: role in regulation of aqueous humor outflow and intraocular pressure in the context of pathobiology and therapy of glaucoma. |
2014 Mar-Apr |
J Ocul Pharmacol Ther |
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Gastric parietal cell atrophy and depletion after administration of a sphingosine-1-phosphate 1 inhibitor. |
2014 |
Toxicol Pathol |
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Corticosteroids inhibit sphingosine 1-phosphate-induced interleukin-6 secretion from human airway smooth muscle via mitogen-activated protein kinase phosphatase 1-mediated repression of mitogen and stress-activated protein kinase 1. |
2014 |
Am. J. Respir. Cell Mol. Biol. |
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Sphingosine 1-phosphate receptors negatively regulate collagen type I/III expression in human bone marrow-derived mesenchymal stem cell. |
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Sphingosine 1-phosphate (S1P) induces COX-2 expression and PGE2 formation via S1P receptor 2 in renal mesangial cells. |
2014 |
Biochim. Biophys. Acta |
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The role of sphingosine 1-phosphate in inflammation and cancer. |
2014 |
Adv Biol Regul |
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Sphingolipid metabolites in inflammatory disease. |
2014 |
Nature |
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Sphingosine-1-phosphate mediates epidermal growth factor-induced muscle satellite cell activation. |
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[Sphingosine 1-phosphate as a biomarker for Alzheimer's disease?]. |
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Med Sci (Paris) |
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Comparison of the serum lipidome in patients with abdominal aortic aneurysm and peripheral artery disease. |
2014 |
Circ Cardiovasc Genet |
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Differential regulation of lung endothelial permeability in vitro and in situ. |
2014 |
Cell. Physiol. Biochem. |
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Reconceptualizing adult neurogenesis: role for sphingosine-1-phosphate and fibroblast growth factor-1 in co-ordinating astrocyte-neuronal precursor interactions. |
2014 |
CNS Neurol Disord Drug Targets |
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Distinct roles for hematopoietic and extra-hematopoietic sphingosine kinase-1 in inflammatory bowel disease. |
2014 |
PLoS ONE |
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Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo. |
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Sphingosine 1-phosphate to p38 signaling via S1P1 receptor and Gαi/o evokes augmentation of capsaicin-induced ionic currents in mouse sensory neurons. |
2014 |
Mol Pain |
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Sphingolipids in lung growth and repair. |
2014 |
Chest |
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Convergent regulation of neuronal differentiation and Erk and Akt kinases in human neural progenitor cells by lysophosphatidic acid, sphingosine 1-phosphate, and LIF: specific roles for the LPA1 receptor. |
2014 |
ASN Neuro |
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An endoplasmic reticulum stress-initiated sphingolipid metabolite, ceramide-1-phosphate, regulates epithelial innate immunity by stimulating β-defensin production. |
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Mol. Cell. Biol. |
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Increased levels of sphingosine-1-phosphate in cerebrospinal fluid of patients diagnosed with tick-borne encephalitis. |
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J Neuroinflammation |
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AP-1 regulates sphingosine kinase 1 expression in a positive feedback manner in glomerular mesangial cells exposed to high glucose. |
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Autophagy in oncogenic K-Ras promotes basal extrusion of epithelial cells by degrading S1P. |
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Curr. Biol. |
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Sphingosine 1-phosphate in acute dengue infection. |
2014 |
PLoS ONE |
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Sphingolipid signaling reduces basal P-glycoprotein activity in renal proximal tubule. |
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J. Pharmacol. Exp. Ther. |
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Sphingosine 1-phosphate: a potential molecular target for ovarian cancer therapy? |
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Cancer Invest. |
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Integrin α9 on lymphatic endothelial cells regulates lymphocyte egress. |
2014 |
Proc. Natl. Acad. Sci. U.S.A. |
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Diacylglycerol kinase γ is a novel anionic phospholipid binding protein with a selective binding preference. |
2014 |
Biochem. Biophys. Res. Commun. |
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Role of Ca2+ -dependent and Ca2+ -sensitive mechanisms in sphingosine 1-phosphate-induced constriction of isolated porcine retinal arterioles in vitro. |
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Exp. Eye Res. |
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Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss. |
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PLoS Genet. |
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Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs. |
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J. Clin. Invest. |
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Improving heart function by modulating myocardiocyte autophagy: a possible novel mechanism for cardiovascular protection of high-density lipoprotein. |
2014 |
Lipids Health Dis |
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Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts. |
2014 |
Nat Commun |
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Early double-negative thymocyte export in Trypanosoma cruzi infection is restricted by sphingosine receptors and associated with human chagas disease. |
2014 |
PLoS Negl Trop Dis |
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Critical role of Spns2, a sphingosine-1-phosphate transporter, in lung cancer cell survival and migration. |
2014 |
PLoS ONE |
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Sphingosine-1-phosphate receptor agonist, FTY720, restores coronary flow reserve in diabetic rats. |
2014 |
Circ. J. |
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S1P-Yap1 signaling regulates endoderm formation required for cardiac precursor cell migration in zebrafish. |
2014 |
Dev. Cell |
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Individual variation of human S1Pâ‚ coding sequence leads to heterogeneity in receptor function and drug interactions. |
2014 |
J. Lipid Res. |
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Chemical and genetic tools to explore S1P biology. |
2014 |
Curr. Top. Microbiol. Immunol. |
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Blood, sphingosine-1-phosphate and lymphocyte migration dynamics in the spleen. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728595
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Cytokine storm plays a direct role in the morbidity and mortality from influenza virus infection and is chemically treatable with a single sphingosine-1-phosphate agonist molecule. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728596
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Sphingosine-1 phosphate and central nervous system. |
2014 |
Curr. Top. Microbiol. Immunol. |
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CXCR4 blockade and sphingosine-1-phosphate activation facilitate engraftment of haematopoietic stem and progenitor cells in a non-myeloablative transplant model. |
2014 |
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STAT3 and sphingosine-1-phosphate in inflammation-associated colorectal cancer. |
2014 |
World J. Gastroenterol. |
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Inflammatory lipid sphingosine-1-phosphate upregulates C-reactive protein via C/EBPβ and potentiates breast cancer progression. |
2014 |
Oncogene |
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Sphingosine Kinase-1/sphingosine 1-phosphate pathway in diabetic nephropathy. |
2014 |
Chin. Med. J. |
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Engineering in vivo gradients of sphingosine-1-phosphate receptor ligands for localized microvascular remodeling and inflammatory cell positioning. |
2014 |
Acta Biomater |
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S1P-Dependent trafficking of intracellular yersinia pestis through lymph nodes establishes Buboes and systemic infection. |
2014 |
Immunity |
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Davis KM and Isberg RR |
Plague's partners in crime. |
2014 |
Immunity |
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Sphingosine-1-phosphate mediates a reciprocal signaling pathway between stellate cells and cancer cells that promotes pancreatic cancer growth. |
2014 |
Am. J. Pathol. |
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FTY720 and cisplatin synergistically induce the death of cisplatin-resistant melanoma cells through the downregulation of the PI3K pathway and the decrease in epidermal growth factor receptor expression. |
2014 |
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SphK1 confers resistance to apoptosis in gastric cancer cells by downregulating Bim via stimulating Akt/FoxO3a signaling. |
2014 |
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Implications of chemokines, chemokine receptors, and inflammatory lipids in atherosclerosis. |
2014 |
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Induction of the matricellular protein CCN1 through RhoA and MRTF-A contributes to ischemic cardioprotection. |
2014 |
J. Mol. Cell. Cardiol. |
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Induction of chemokine (C-C motif) ligand 2 by sphingosine-1-phosphate signaling in neuroblastoma. |
2014 |
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Targeting the sphingosine kinase/sphingosine 1-phosphate pathway to treat chronic inflammatory kidney diseases. |
2014 |
Basic Clin. Pharmacol. Toxicol. |
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Antiapoptotic agent sphingosine-1-phosphate protects vitrified murine ovarian grafts. |
2014 |
Reprod Sci |
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Sphingosine 1-phosphate induces neutrophil chemoattractant IL-8: repression by steroids. |
2014 |
PLoS ONE |
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Sphingolipids: important players in multiple sclerosis. |
2014 |
Cell. Physiol. Biochem. |
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Sphingosine-1-phosphate lyase is expressed by CD68+ cells on the parenchymal side of marginal reticular cells in human lymph nodes. |
2014 |
Eur. J. Immunol. |
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Sphingosine-1-phosphate modulates dendritic cell function: focus on non-migratory effects in vitro and in vivo. |
2014 |
Cell. Physiol. Biochem. |
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Sphingosine-1-phosphate: a master regulator of lymphocyte egress and immunity. |
2014 |
Arch. Immunol. Ther. Exp. (Warsz.) |
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Re-configuration of sphingolipid metabolism by oncogenic transformation. |
2014 |
Biomolecules |
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Translational pharmacokinetic modeling of fingolimod (FTY720) as a paradigm compound subject to sphingosine kinase-mediated phosphorylation. |
2014 |
Drug Metab. Dispos. |
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Mechanosensing at the vascular interface. |
2014 |
Annu Rev Biomed Eng |
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Atheroprotective role of high-density lipoprotein (HDL)-associated sphingosine-1-phosphate (S1P). |
2014 |
Cardiovasc. Res. |
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Exogenous sphingosine-1-phosphate boosts acclimatization in rats exposed to acute hypobaric hypoxia: assessment of haematological and metabolic effects. |
2014 |
PLoS ONE |
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The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1. |
2014 |
J. Biol. Chem. |
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Adiponectin regulates SR Ca(2+) cycling following ischemia/reperfusion via sphingosine 1-phosphate-CaMKII signaling in mice. |
2014 |
J. Mol. Cell. Cardiol. |
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Arguing the case for the autotaxin-lysophosphatidic acid-lipid phosphate phosphatase 3-signaling nexus in the development and complications of atherosclerosis. |
2014 |
Arterioscler. Thromb. Vasc. Biol. |
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Amphiphilic degradable polymers for immobilization and sustained delivery of sphingosine 1-phosphate. |
2014 |
Acta Biomater |
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S1PR1 is crucial for accumulation of regulatory T cells in tumors via STAT3. |
2014 |
Cell Rep |
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Pseudomonas-derived ceramidase induces production of inflammatory mediators from human keratinocytes via sphingosine-1-phosphate. |
2014 |
PLoS ONE |
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Sphingosine-1-phosphate evokes unique segment-specific vasoconstriction of the renal microvasculature. |
2014 |
J. Am. Soc. Nephrol. |
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Export of sphingosine-1-phosphate and cancer progression. |
2014 |
J. Lipid Res. |
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Sphingosine-1-phosphate induces differentiation of cultured renal tubular epithelial cells under Rho kinase activation via the S1P2 receptor. |
2014 |
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Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer's disease pathogenesis. |
2014 |
Acta Neuropathol Commun |
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Sphingosine kinases/sphingosine-1-phosphate and death Signalling in APP-transfected cells. |
2014 |
Neurochem. Res. |
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The expression of sphingosine-1 phosphate receptor-1 in chronic lymphocytic leukemia cells is impaired by tumor microenvironmental signals and enhanced by piceatannol and R406. |
2014 |
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Sphingosine-1-phosphate signalling as a therapeutic target for patients with abnormal glucose metabolism and ischaemic heart disease. |
2014 |
J Cardiovasc Med (Hagerstown) |
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The identification of GPR3 inverse agonist AF64394; the first small molecule inhibitor of GPR3 receptor function. |
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Bioorg. Med. Chem. Lett. |
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Identification of a novel small-molecule agonist for human G protein-coupled receptor 3. |
2014 |
J. Pharmacol. Exp. Ther. |
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Pyszko J and Strosznajder JB |
Sphingosine kinase 1 and sphingosine-1-phosphate in oxidative stress evoked by 1-methyl-4-phenylpyridinium (MPP+) in human dopaminergic neuronal cells. |
2014 |
Mol. Neurobiol. |
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Lysophosphatidic acid stimulates cell migration of satellite cells. A role for the sphingosine kinase/sphingosine 1-phosphate axis. |
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FEBS J. |
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Exogenous sphingosine 1-phosphate protects murine splenocytes against hypoxia-induced injury. |
2014 |
Lipids |
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