Al Alam N and Kreydiyyeh SI |
FTY720P inhibits hepatic Na(+)-K(+) ATPase via S1PR2 and PGE2. |
2016 |
Biochem. Cell Biol. |
pmid:27501354
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Fu P et al. |
Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium. |
2016 |
J. Biol. Chem. |
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Terashita T et al. |
Administration of JTE013 abrogates experimental asthma by regulating proinflammatory cytokine production from bronchial epithelial cells. |
2016 |
Respir. Res. |
pmid:27829417
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Brait VH et al. |
Selective Sphingosine 1-Phosphate Receptor 1 Agonist Is Protective Against Ischemia/Reperfusion in Mice. |
2016 |
Stroke |
pmid:27827329
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Chew WS et al. |
To fingolimod and beyond: The rich pipeline of drug candidates that target S1P signaling. |
2016 |
Pharmacol. Res. |
pmid:27663260
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Gstalder C et al. |
FTY720 (Fingolimod) Inhibits HIF1 and HIF2 Signaling, Promotes Vascular Remodeling, and Chemosensitizes in Renal Cell Carcinoma Animal Model. |
2016 |
Mol. Cancer Ther. |
pmid:27507852
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Hashimoto Y et al. |
Sphingosine-1-phosphate-enhanced Wnt5a promotes osteogenic differentiation in C3H10T1/2 cells. |
2016 |
Cell Biol. Int. |
pmid:27486054
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Viswanathan P et al. |
Differential elastic responses to barrier-altering agonists in two types of human lung endothelium. |
2016 |
Biochem. Biophys. Res. Commun. |
pmid:27473658
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Moruno Manchon JF et al. |
SPHK1/sphingosine kinase 1-mediated autophagy differs between neurons and SH-SY5Y neuroblastoma cells. |
2016 |
Autophagy |
pmid:27467777
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Nagahashi M et al. |
The roles of bile acids and sphingosine-1-phosphate signaling in the hepatobiliary diseases. |
2016 |
J. Lipid Res. |
pmid:27459945
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Poissonnier A et al. |
CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice. |
2016 |
Immunity |
pmid:27438772
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Zhang Q et al. |
Berberine Preconditioning Protects Neurons Against Ischemia via Sphingosine-1-Phosphate and Hypoxia-Inducible Factor-1[Formula: see text]. |
2016 |
Am. J. Chin. Med. |
pmid:27430910
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Rumzhum NN et al. |
Effect of Sphingosine 1-Phosphate on Cyclo-Oxygenase-2 Expression, Prostaglandin E2 Secretion, and β2-Adrenergic Receptor Desensitization. |
2016 |
Am. J. Respir. Cell Mol. Biol. |
pmid:26098693
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Sauvé M et al. |
Tumor Necrosis Factor/Sphingosine-1-Phosphate Signaling Augments Resistance Artery Myogenic Tone in Diabetes. |
2016 |
Diabetes |
pmid:27207546
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Zhang XE et al. |
Activation of RhoA, but Not Rac1, Mediates Early Stages of S1P-Induced Endothelial Barrier Enhancement. |
2016 |
PLoS ONE |
pmid:27187066
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Ohtoyo M et al. |
Component of Caramel Food Coloring, THI, Causes Lymphopenia Indirectly via a Key Metabolic Intermediate. |
2016 |
Cell Chem Biol |
pmid:27185637
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Fleming JK et al. |
A novel approach for measuring sphingosine-1-phosphate and lysophosphatidic acid binding to carrier proteins using monoclonal antibodies and the Kinetic Exclusion Assay. |
2016 |
J. Lipid Res. |
pmid:27444045
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Barnawi J et al. |
Pro-phagocytic Effects of Thymoquinone on Cigarette Smoke-exposed Macrophages Occur by Modulation of the Sphingosine-1-phosphate Signalling System. |
2016 |
COPD |
pmid:27144721
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Jin L et al. |
The SphKs/S1P/S1PR1 axis in immunity and cancer: more ore to be mined. |
2016 |
World J Surg Oncol |
pmid:27129720
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Nagura Y et al. |
Regulation of the lysophosphatidylserine and sphingosine 1-phosphate levels in autologous whole blood by the pre-storage leukocyte reduction. |
2016 |
Transfus Med |
pmid:27350440
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Sanchez T |
Sphingosine-1-Phosphate Signaling in Endothelial Disorders. |
2016 |
Curr Atheroscler Rep |
pmid:27115142
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Crespo I et al. |
Melatonin inhibits the sphingosine kinase 1/sphingosine-1-phosphate signaling pathway in rabbits with fulminant hepatitis of viral origin. |
2016 |
J. Pineal Res. |
pmid:27101794
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Riganti L et al. |
Sphingosine-1-Phosphate (S1P) Impacts Presynaptic Functions by Regulating Synapsin I Localization in the Presynaptic Compartment. |
2016 |
J. Neurosci. |
pmid:27098703
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Trinh HK et al. |
Exploration of the Sphingolipid Metabolite, Sphingosine-1-phosphate and Sphingosine, as Novel Biomarkers for Aspirin-exacerbated Respiratory Disease. |
2016 |
Sci Rep |
pmid:27830727
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Tang X et al. |
Tetracyclines increase lipid phosphate phosphatase expression on plasma membranes and turnover of plasma lysophosphatidate. |
2016 |
J. Lipid Res. |
pmid:26884614
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Bien-Möller S et al. |
Expression of S1P metabolizing enzymes and receptors correlate with survival time and regulate cell migration in glioblastoma multiforme. |
2016 |
Oncotarget |
pmid:26887055
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Uranbileg B et al. |
Increased mRNA Levels of Sphingosine Kinases and S1P Lyase and Reduced Levels of S1P Were Observed in Hepatocellular Carcinoma in Association with Poorer Differentiation and Earlier Recurrence. |
2016 |
PLoS ONE |
pmid:26886371
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Chumanevich A et al. |
Sphingosine-1-Phosphate/Sphingosine-1-Phosphate Receptor 2 Axis Can Promote Mouse and Human Primary Mast Cell Angiogenic Potential through Upregulation of Vascular Endothelial Growth Factor-A and Matrix Metalloproteinase-2. |
2016 |
Mediators Inflamm. |
pmid:26884643
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Ko P et al. |
Extracellular Matrix Rigidity-dependent Sphingosine-1-phosphate Secretion Regulates Metastatic Cancer Cell Invasion and Adhesion. |
2016 |
Sci Rep |
pmid:26877098
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Luo B et al. |
Erythropoeitin Signaling in Macrophages Promotes Dying Cell Clearance and Immune Tolerance. |
2016 |
Immunity |
pmid:26872696
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Li J et al. |
Overexpression of SphK1 enhances cell proliferation and invasion in triple-negative breast cancer via the PI3K/AKT signaling pathway. |
2016 |
Tumour Biol. |
pmid:26857281
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Camaré C et al. |
The neutral sphingomyelinase-2 is involved in angiogenic signaling triggered by oxidized LDL. |
2016 |
Free Radic. Biol. Med. |
pmid:26855418
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Petrache I and Berdyshev EV |
Ceramide Signaling and Metabolism in Pathophysiological States of the Lung. |
2016 |
Annu. Rev. Physiol. |
pmid:26667073
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Delgado A and MartÃnez-Cartro M |
Therapeutic Potential of the Modulation of Sphingosine-1-Phosphate Receptors. |
2016 |
Curr. Med. Chem. |
pmid:26639095
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Yamamoto S et al. |
A role of the sphingosine-1-phosphate (S1P)-S1P receptor 2 pathway in epithelial defense against cancer (EDAC). |
2016 |
Mol. Biol. Cell |
pmid:26631556
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Hepatocytes release ceramide-enriched pro-inflammatory extracellular vesicles in an IRE1α-dependent manner. |
2016 |
J. Lipid Res. |
pmid:26621917
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Chen J et al. |
Deletion of sphingosine kinase 1 ameliorates hepatic steatosis in diet-induced obese mice: Role of PPARγ. |
2016 |
Biochim. Biophys. Acta |
pmid:26615875
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Maczis M et al. |
Sphingosine-1-phosphate and estrogen signaling in breast cancer. |
2016 |
Adv Biol Regul |
pmid:26601898
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Zhang F et al. |
Sphingosine 1-phosphate signaling contributes to cardiac inflammation, dysfunction, and remodeling following myocardial infarction. |
2016 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:26589326
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Li S et al. |
Sphk1 promotes breast epithelial cell proliferation via NF-κB-p65-mediated cyclin D1 expression. |
2016 |
Oncotarget |
pmid:27811358
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Gao D et al. |
Metabolomics study on the antitumor effect of marine natural compound flexibilide in HCT-116 colon cancer cell line. |
2016 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:26859520
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Scotti L et al. |
Sphingosine-1-phosphate restores endothelial barrier integrity in ovarian hyperstimulation syndrome. |
2016 |
Mol. Hum. Reprod. |
pmid:27645281
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Neubauer HA et al. |
An oncogenic role for sphingosine kinase 2. |
2016 |
Oncotarget |
pmid:27588496
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Zeng Y et al. |
Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-β autocrine loop. |
2016 |
Oncotarget |
pmid:27556509
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Nagahashi M et al. |
Interstitial Fluid Sphingosine-1-Phosphate in Murine Mammary Gland and Cancer and Human Breast Tissue and Cancer Determined by Novel Methods. |
2016 |
J Mammary Gland Biol Neoplasia |
pmid:27194029
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Nigro E et al. |
Role of adiponectin in sphingosine-1-phosphate induced airway hyperresponsiveness and inflammation. |
2016 |
Pharmacol. Res. |
pmid:26462929
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Serdar M et al. |
Fingolimod protects against neonatal white matter damage and long-term cognitive deficits caused by hyperoxia. |
2016 |
Brain Behav. Immun. |
pmid:26456693
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Arish M et al. |
Sphingosine-1-phosphate signaling: unraveling its role as a drug target against infectious diseases. |
2016 |
Drug Discov. Today |
pmid:26456576
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Kurano M et al. |
Resveratrol exerts a biphasic effect on apolipoprotein M. |
2016 |
Br. J. Pharmacol. |
pmid:26445217
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Melnik BC |
Rosacea: The Blessing of the Celts - An Approach to Pathogenesis Through Translational Research. |
2016 |
Acta Derm. Venereol. |
pmid:26304030
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