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Differential Effects of Long Term FTY720 Treatment on Endothelial versus Smooth Muscle Cell Signaling to S1P in Rat Mesenteric Arteries. |
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PLoS ONE |
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Platelet and Erythrocyte Sources of S1P Are Redundant for Vascular Development and Homeostasis, but Both Rendered Essential After Plasma S1P Depletion in Anaphylactic Shock. |
2016 |
Circ. Res. |
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Cellular function and signaling pathways of vascular smooth muscle cells modulated by sphingosine 1-phosphate. |
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J. Pharmacol. Sci. |
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Sphingosine-1-phosphate modulators in inflammatory skin diseases - lining up for clinical translation. |
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Exp. Dermatol. |
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High levels of sphingolipids in human breast cancer. |
2016 |
J. Surg. Res. |
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Sphingolipid De Novo Biosynthesis: A Rheostat of Cardiovascular Homeostasis. |
2016 |
Trends Endocrinol. Metab. |
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Cortisol-induced immune suppression by a blockade of lymphocyte egress in traumatic brain injury. |
2016 |
J Neuroinflammation |
pmid:27561600
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Zeng Y et al. |
Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-β autocrine loop. |
2016 |
Oncotarget |
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Nojima H et al. |
Chemokine Receptors, CXCR1 and CXCR2, Differentially Regulate Exosome Release in Hepatocytes. |
2016 |
PLoS ONE |
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HuR mediates motility of human bone marrow-derived mesenchymal stem cells triggered by sphingosine 1-phosphate in liver fibrosis. |
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J. Mol. Med. |
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A facile enzymatic synthesis of sphingosine-1-phosphate and dihydrosphingosine-1-phosphate. |
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J. Lipid Res. |
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Sphingosine-1-Phosphate (S1P) Lyase Inhibition Causes Increased Cardiac S1P Levels and Bradycardia in Rats. |
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J. Pharmacol. Exp. Ther. |
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FTY720 (Fingolimod) Inhibits HIF1 and HIF2 Signaling, Promotes Vascular Remodeling, and Chemosensitizes in Renal Cell Carcinoma Animal Model. |
2016 |
Mol. Cancer Ther. |
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Al Alam N and Kreydiyyeh SI |
FTY720P inhibits hepatic Na(+)-K(+) ATPase via S1PR2 and PGE2. |
2016 |
Biochem. Cell Biol. |
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Hashimoto Y et al. |
Sphingosine-1-phosphate-enhanced Wnt5a promotes osteogenic differentiation in C3H10T1/2 cells. |
2016 |
Cell Biol. Int. |
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Therapeutic Strategies and Pharmacological Tools Influencing S1P Signaling and Metabolism. |
2017 |
Med Res Rev |
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Binding Characteristics of Sphingosine-1-Phosphate to ApoM hints to Assisted Release Mechanism via the ApoM Calyx-Opening. |
2016 |
Sci Rep |
pmid:27476912
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Viswanathan P et al. |
Differential elastic responses to barrier-altering agonists in two types of human lung endothelium. |
2016 |
Biochem. Biophys. Res. Commun. |
pmid:27473658
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Moruno Manchon JF et al. |
SPHK1/sphingosine kinase 1-mediated autophagy differs between neurons and SH-SY5Y neuroblastoma cells. |
2016 |
Autophagy |
pmid:27467777
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Therapeutic potential of targeting sphingosine kinases and sphingosine 1-phosphate in hematological malignancies. |
2016 |
Leukemia |
pmid:27461062
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Nagahashi M et al. |
The roles of bile acids and sphingosine-1-phosphate signaling in the hepatobiliary diseases. |
2016 |
J. Lipid Res. |
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A novel approach for measuring sphingosine-1-phosphate and lysophosphatidic acid binding to carrier proteins using monoclonal antibodies and the Kinetic Exclusion Assay. |
2016 |
J. Lipid Res. |
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Poissonnier A et al. |
CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice. |
2016 |
Immunity |
pmid:27438772
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Berberine Preconditioning Protects Neurons Against Ischemia via Sphingosine-1-Phosphate and Hypoxia-Inducible Factor-1[Formula: see text]. |
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Am. J. Chin. Med. |
pmid:27430910
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Adamiak M et al. |
Downregulation of Heme Oxygenase 1 (HO-1) Activity in Hematopoietic Cells Enhances Their Engraftment After Transplantation. |
2016 |
Cell Transplant |
pmid:27412411
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Structural Insight into Substrate Selection and Catalysis of Lipid Phosphate Phosphatase PgpB in the Cell Membrane. |
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J. Biol. Chem. |
pmid:27405756
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ApoA-I induces S1P release from endothelial cells through ABCA1 and SR-BI in a positive feedback manner. |
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J. Physiol. Biochem. |
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Effect of sphingosine-1-phosphate on L-type calcium current and Ca(2+) transient in rat ventricular myocytes. |
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Mol. Cell. Biochem. |
pmid:27372350
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Sphingosine 1‑phosphate induced by hypoxia increases the expression of PAI‑1 in HepG2 cells via HIF‑1α. |
2016 |
Mol Med Rep |
pmid:27357063
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Sphingosine 1-phosphate signaling impacts lymphocyte migration, inflammation and infection. |
2016 |
Pathog Dis |
pmid:27354294
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Lipocalin 2 from macrophages stimulated by tumor cell-derived sphingosine 1-phosphate promotes lymphangiogenesis and tumor metastasis. |
2016 |
Sci Signal |
pmid:27353364
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Tumor microenvironment on the move and the Aselli connection. |
2016 |
Sci Signal |
pmid:27353363
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Nagura Y et al. |
Regulation of the lysophosphatidylserine and sphingosine 1-phosphate levels in autologous whole blood by the pre-storage leukocyte reduction. |
2016 |
Transfus Med |
pmid:27350440
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Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium. |
2016 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:27343196
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Sphingosine-1-phosphate, regulated by FSH and VEGF, stimulates granulosa cell proliferation. |
2016 |
Gen. Comp. Endocrinol. |
pmid:27342378
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Ceramide and Sphingosine-1-Phosphate in Cell Death Pathways : Relevance to the Pathogenesis of Alzheimer's Disease. |
2016 |
Curr Alzheimer Res |
pmid:27335046
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Non-dioxin-like organic toxicant PCB153 modulates sphingolipid metabolism in liver progenitor cells: its role in Cx43-formed gap junction impairment. |
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Arch. Toxicol. |
pmid:27318803
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Tsai HC and Han MH |
Sphingosine-1-Phosphate (S1P) and S1P Signaling Pathway: Therapeutic Targets in Autoimmunity and Inflammation. |
2016 |
Drugs |
pmid:27318702
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Yang Z et al. |
TGR5 activation suppressed S1P/S1P2 signaling and resisted high glucose-induced fibrosis in glomerular mesangial cells. |
2016 |
Pharmacol. Res. |
pmid:27317945
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Cantalupo A and Di Lorenzo A |
S1P Signaling and De Novo Biosynthesis in Blood Pressure Homeostasis. |
2016 |
J. Pharmacol. Exp. Ther. |
pmid:27317800
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Gharbaran R |
Insights into the molecular roles of heparan sulfate proteoglycans (HSPGs-syndecans) in autocrine and paracrine growth factor signaling in the pathogenesis of Hodgkin's lymphoma. |
2016 |
Tumour Biol. |
pmid:27317256
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Juif PE et al. |
Clinical pharmacology, efficacy, and safety aspects of sphingosine-1-phosphate receptor modulators. |
2016 |
Expert Opin Drug Metab Toxicol |
pmid:27249325
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Puli MR et al. |
Stomatal closure induced by phytosphingosine-1-phosphate and sphingosine-1-phosphate depends on nitric oxide and pH of guard cells in Pisum sativum. |
2016 |
Planta |
pmid:27233507
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Hollands A et al. |
Natural Product Anacardic Acid from Cashew Nut Shells Stimulates Neutrophil Extracellular Trap Production and Bactericidal Activity. |
2016 |
J. Biol. Chem. |
pmid:27226531
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Mirzaian M et al. |
Accurate quantification of sphingosine-1-phosphate in normal and Fabry disease plasma, cells and tissues by LC-MS/MS with (13)C-encoded natural S1P as internal standard. |
2016 |
Clin. Chim. Acta |
pmid:27221202
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[Role and related mechanism of S1P/S1P1 signal pathway during post conditioning of hypertrophic cardiomyocytes]. |
2016 |
Zhonghua Xin Xue Guan Bing Za Zhi |
pmid:27220580
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Marfia G et al. |
The Adipose Mesenchymal Stem Cell Secretome Inhibits Inflammatory Responses of Microglia: Evidence for an Involvement of Sphingosine-1-Phosphate Signalling. |
2016 |
Stem Cells Dev. |
pmid:27217090
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Gudipaty SA and Rosenblatt J |
Epithelial cell extrusion: Pathways and pathologies. |
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Semin. Cell Dev. Biol. |
pmid:27212253
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Familial hypercholesterolaemia: cholesterol efflux and coronary disease. |
2016 |
Eur. J. Clin. Invest. |
pmid:27208892
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Sauvé M et al. |
Tumor Necrosis Factor/Sphingosine-1-Phosphate Signaling Augments Resistance Artery Myogenic Tone in Diabetes. |
2016 |
Diabetes |
pmid:27207546
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