Dong T et al. |
Cortisol-induced immune suppression by a blockade of lymphocyte egress in traumatic brain injury. |
2016 |
J Neuroinflammation |
pmid:27561600
|
Kułakowska A et al. |
Increased levels of sphingosine-1-phosphate in cerebrospinal fluid of patients diagnosed with tick-borne encephalitis. |
2014 |
J Neuroinflammation |
pmid:25421616
|
Hoffmann FS et al. |
Fingolimod induces neuroprotective factors in human astrocytes. |
2015 |
J Neuroinflammation |
pmid:26419927
|
Li C et al. |
Sphingosine 1-phosphate enhances the excitability of rat sensory neurons through activation of sphingosine 1-phosphate receptors 1 and/or 3. |
2015 |
J Neuroinflammation |
pmid:25880547
|
He X et al. |
Sphingosine-1-phosphate mediates proliferation maintaining the multipotency of human adult bone marrow and adipose tissue-derived stem cells. |
2010 |
J Mol Cell Biol |
pmid:20584786
|
Nagahashi M et al. |
Interstitial Fluid Sphingosine-1-Phosphate in Murine Mammary Gland and Cancer and Human Breast Tissue and Cancer Determined by Novel Methods. |
2016 |
J Mammary Gland Biol Neoplasia |
pmid:27194029
|
Spiegel S |
Sphingosine and sphingosine 1-phosphate in cellular proliferation: relationship with protein kinase C and phosphatidic acid. |
1993 |
J Lipid Mediat |
pmid:8268463
|
Rokka J et al. |
19F/18F exchange synthesis for a novel [18F]S1P3-radiopharmaceutical. |
2013 |
J Labelled Comp Radiopharm |
pmid:24285478
|
Komatsu I et al. |
Dupuytren's fibroblast contractility by sphingosine-1-phosphate is mediated through non-muscle myosin II. |
2010 |
J Hand Surg Am |
pmid:20888494
|
Howard C et al. |
Dental pulp stem cell migration. |
2010 |
J Endod |
pmid:21092813
|
Kurek K et al. |
Inhibition of Ceramide De Novo Synthesis Ameliorates Diet Induced Skeletal Muscles Insulin Resistance. |
2015 |
J Diabetes Res |
pmid:26380311
|
Rohatagi S et al. |
Use of an exposure-response model to aid early drug development of an oral sphingosine 1-phosphate receptor modulator. |
2009 |
J Clin Pharmacol |
pmid:18948412
|
Egom EE |
Sphingosine-1-phosphate signalling as a therapeutic target for patients with abnormal glucose metabolism and ischaemic heart disease. |
2014 |
J Cardiovasc Med (Hagerstown) |
pmid:23839592
|
Tabasinezhad M et al. |
Sphingosin 1-phosphate contributes in tumor progression. |
|
J Cancer Res Ther |
pmid:24518696
|
Southern C et al. |
Screening β-arrestin recruitment for the identification of natural ligands for orphan G-protein-coupled receptors. |
2013 |
J Biomol Screen |
pmid:23396314
|
Wetter JA et al. |
Utilization of the Tango beta-arrestin recruitment technology for cell-based EDG receptor assay development and interrogation. |
2009 |
J Biomol Screen |
pmid:19726785
|
Highkin MK et al. |
High-throughput screening assay for sphingosine kinase inhibitors in whole blood using RapidFire® mass spectrometry. |
2011 |
J Biomol Screen |
pmid:21297110
|
Niedernberg A et al. |
Comparative analysis of functional assays for characterization of agonist ligands at G protein-coupled receptors. |
2003 |
J Biomol Screen |
pmid:14567777
|
Alford SK et al. |
Endothelial cell migration in human plasma is enhanced by a narrow range of added sphingosine 1-phosphate: implications for biomaterials design. |
2009 |
J Biomed Mater Res A |
pmid:18286622
|
Kim YH and Tabata Y |
Recruitment of mesenchymal stem cells and macrophages by dual release of stromal cell-derived factor-1 and a macrophage recruitment agent enhances wound closure. |
2016 |
J Biomed Mater Res A |
pmid:26704185
|
Marycz K et al. |
The influence of metal-based biomaterials functionalized with sphingosine-1-phosphate on the cellular response and osteogenic differentaion potenial of human adipose derived mesenchymal stem cells in vitro. |
2016 |
J Biomater Appl |
pmid:26801473
|
Leclercq TM and Pitson SM |
Cellular signalling by sphingosine kinase and sphingosine 1-phosphate. |
2006 |
IUBMB Life |
pmid:16916784
|
GarcÃa-Sáinz JA et al. |
Mechanisms involved in α1B-adrenoceptor desensitization. |
2011 |
IUBMB Life |
pmid:21815242
|
Chawla S et al. |
S1P prophylaxis mitigates acute hypobaric hypoxia-induced molecular, biochemical, and metabolic disturbances: A preclinical report. |
2016 |
IUBMB Life |
pmid:26959531
|
Siess W et al. |
Lysophosphatidic acid and sphingosine 1-phosphate: two lipid villains provoking cardiovascular diseases? |
2000 |
IUBMB Life |
pmid:10868905
|
Kim JH et al. |
Sphingosine 1-phosphate activates Erk-1/-2 by transactivating epidermal growth factor receptor in rat-2 cells. |
2000 |
IUBMB Life |
pmid:11185956
|
Meacci E et al. |
Sphingosine 1-phosphate signal transduction in muscle cells. |
2003 |
Ital. J. Biochem. |
pmid:12833634
|
Sabbadini RA et al. |
The role of sphingolipids in the control of skeletal muscle function: a review. |
1999 |
Ital J Neurol Sci |
pmid:10937863
|
Lee H et al. |
4-Deoxypyridoxine improves the viability of isolated pancreatic islets ex vivo. |
2013 May-Jun |
Islets |
pmid:23756681
|
Boussommier-Calleja A et al. |
Pharmacologic manipulation of conventional outflow facility in ex vivo mouse eyes. |
2012 |
Invest. Ophthalmol. Vis. Sci. |
pmid:22807298
|
Miranda GE et al. |
Sphingosine-1-phosphate is a key regulator of proliferation and differentiation in retina photoreceptors. |
2009 |
Invest. Ophthalmol. Vis. Sci. |
pmid:19357361
|
Kim SE et al. |
The Role of Sphingosine-1-Phosphate in Adipogenesis of Graves' Orbitopathy. |
2016 |
Invest. Ophthalmol. Vis. Sci. |
pmid:26830367
|
Wang J et al. |
Receptor-mediated activation of a Cl(-) current by LPA and S1P in cultured corneal keratocytes. |
2002 |
Invest. Ophthalmol. Vis. Sci. |
pmid:12356825
|
Qiao Y et al. |
Sphingosine 1-phosphate elicits proinflammatory responses in ARPE-19 cells. |
2012 |
Invest. Ophthalmol. Vis. Sci. |
pmid:23150617
|
Simón MV et al. |
Sphingosine-1-Phosphate Is a Crucial Signal for Migration of Retina Müller Glial Cells. |
2015 |
Invest. Ophthalmol. Vis. Sci. |
pmid:26325420
|
Yin F and Watsky MA |
LPA and S1P increase corneal epithelial and endothelial cell transcellular resistance. |
2005 |
Invest. Ophthalmol. Vis. Sci. |
pmid:15914605
|
Abrahan CE et al. |
Synthesis of sphingosine is essential for oxidative stress-induced apoptosis of photoreceptors. |
2010 |
Invest. Ophthalmol. Vis. Sci. |
pmid:19797232
|
Sumida GM and Stamer WD |
Sphingosine-1-phosphate enhancement of cortical actomyosin organization in cultured human Schlemm's canal endothelial cell monolayers. |
2010 |
Invest. Ophthalmol. Vis. Sci. |
pmid:20592229
|
Ko J et al. |
Sphingosine-1-Phosphate Mediates Fibrosis in Orbital Fibroblasts in Graves' Orbitopathy. |
2017 |
Invest. Ophthalmol. Vis. Sci. |
pmid:28492873
|
Aoyama-Araki Y et al. |
Sphingosine-1-Phosphate (S1P)-Related Response of Human Conjunctival Fibroblasts After Filtration Surgery for Glaucoma. |
2017 |
Invest. Ophthalmol. Vis. Sci. |
pmid:28418499
|
Durham JT et al. |
Pericyte chemomechanics and the angiogenic switch: insights into the pathogenesis of proliferative diabetic retinopathy? |
2015 |
Invest. Ophthalmol. Vis. Sci. |
pmid:26030100
|
Ling B et al. |
Sphingosine-1-phosphate: a potential therapeutic agent against human breast cancer. |
2011 |
Invest New Drugs |
pmid:20041340
|
Babahosseini H et al. |
Bioactive sphingolipid metabolites modulate ovarian cancer cell structural mechanics. |
2013 |
Integr Biol (Camb) |
pmid:24056950
|
Salmanzadeh A et al. |
Sphingolipid metabolites modulate dielectric characteristics of cells in a mouse ovarian cancer progression model. |
2013 |
Integr Biol (Camb) |
pmid:23609351
|
Lim SH et al. |
Complementary effects of ciclopirox olamine, a prolyl hydroxylase inhibitor and sphingosine 1-phosphate on fibroblasts and endothelial cells in driving capillary sprouting. |
2013 |
Integr Biol (Camb) |
pmid:24190477
|
Won J and Lee GH |
T-cell-targeted signaling inhibitors. |
2008 Jan-Apr |
Int. Rev. Immunol. |
pmid:18300054
|
Lagadari M et al. |
Sphingosine-1-phosphate inhibits the cytotoxic activity of NK cells via Gs protein-mediated signalling. |
2009 |
Int. J. Oncol. |
pmid:19082500
|
Hsu A et al. |
Sphingosine-1-phosphate receptor-3 signaling up-regulates epidermal growth factor receptor and enhances epidermal growth factor receptor-mediated carcinogenic activities in cultured lung adenocarcinoma cells. |
2012 |
Int. J. Oncol. |
pmid:22344462
|
Ng ML et al. |
The role of sphingolipid signalling in diabetes‑associated pathologies (Review). |
2017 |
Int. J. Mol. Med. |
pmid:28075451
|
Moon MH et al. |
Sphingosine-1-phosphate inhibits interleukin-1β-induced inflammation in human articular chondrocytes. |
2012 |
Int. J. Mol. Med. |
pmid:22992945
|
Renkl A et al. |
Distinct effects of sphingosine-1-phosphate, lysophosphatidic acid and histamine in human and mouse dendritic cells. |
2004 |
Int. J. Mol. Med. |
pmid:14719124
|
Lim J et al. |
Valproic acid enforces the priming effect of sphingosine-1 phosphate on human mesenchymal stem cells. |
2017 |
Int. J. Mol. Med. |
pmid:28677769
|
Chen W et al. |
Sphingosine 1-phosphate in metabolic syndrome (Review). |
2016 |
Int. J. Mol. Med. |
pmid:27600830
|
Minamitani C et al. |
Involvement of Rho-kinase in sphingosine 1-phosphate-stimulated HSP27 induction in osteoblasts. |
2009 |
Int. J. Mol. Med. |
pmid:19513538
|
Natsume H et al. |
(-)-Epigallocatechin gallate attenuates the induction of HSP27 stimulated by sphingosine 1-phosphate via suppression of phosphatidylinositol 3-kinase/Akt pathway in osteoblasts. |
2009 |
Int. J. Mol. Med. |
pmid:19578793
|
Ishitsuka A et al. |
FTY720 and cisplatin synergistically induce the death of cisplatin-resistant melanoma cells through the downregulation of the PI3K pathway and the decrease in epidermal growth factor receptor expression. |
2014 |
Int. J. Mol. Med. |
pmid:25109763
|
Moon MH et al. |
Sphingosine-1-phosphate inhibits the adipogenic differentiation of 3T3-L1 preadipocytes. |
2014 |
Int. J. Mol. Med. |
pmid:25050633
|
Lee YJ et al. |
Sphingosine-1-phosphate protects against bisphosphonate‑induced HUVEC cell death via regulation of c-Jun‑N‑terminal kinase signaling. |
2013 |
Int. J. Mol. Med. |
pmid:23381659
|
Sobue S et al. |
Implications of sphingosine kinase 1 expression level for the cellular sphingolipid rheostat: relevance as a marker for daunorubicin sensitivity of leukemia cells. |
2008 |
Int. J. Hematol. |
pmid:18283525
|
Polzin A et al. |
Aspirin inhibits release of platelet-derived sphingosine-1-phosphate in acute myocardial infarction. |
2013 |
Int. J. Cardiol. |
pmid:24169533
|
Lee KP et al. |
DJ-1-mediated upregulation of serine palmitoyltransferase 2 controls vascular neointima via S1P autocrine. |
2015 |
Int. J. Cardiol. |
pmid:25978603
|
Ohotski J et al. |
Identification of novel functional and spatial associations between sphingosine kinase 1, sphingosine 1-phosphate receptors and other signaling proteins that affect prognostic outcome in estrogen receptor-positive breast cancer. |
2013 |
Int. J. Cancer |
pmid:22733311
|
Beckham TH et al. |
Acid ceramidase-mediated production of sphingosine 1-phosphate promotes prostate cancer invasion through upregulation of cathepsin B. |
2012 |
Int. J. Cancer |
pmid:22322590
|
Weigert A et al. |
Sphingosine kinase 2 deficient tumor xenografts show impaired growth and fail to polarize macrophages towards an anti-inflammatory phenotype. |
2009 |
Int. J. Cancer |
pmid:19618460
|
Wang S et al. |
A polysaccharides MDG-1 augments survival in the ischemic heart by inducing S1P release and S1P1 expression. |
2012 |
Int. J. Biol. Macromol. |
pmid:22197795
|
Zebol JR et al. |
The CCT/TRiC chaperonin is required for maturation of sphingosine kinase 1. |
2009 |
Int. J. Biochem. Cell Biol. |
pmid:18775504
|
Korbelik M et al. |
Ceramide and sphingosine-1-phosphate act as photodynamic therapy-elicited damage-associated molecular patterns: cell surface exposure. |
2014 |
Int. Immunopharmacol. |
pmid:24713544
|
Beyer T and Meyer-Hermann M |
Mechanisms of organogenesis of primary lymphoid follicles. |
2008 |
Int. Immunol. |
pmid:18334502
|
Jung ID et al. |
Sphingosine kinase inhibitor suppresses a Th1 polarization via the inhibition of immunostimulatory activity in murine bone marrow-derived dendritic cells. |
2007 |
Int. Immunol. |
pmid:17307797
|
Maeda Y et al. |
S1P lyase in thymic perivascular spaces promotes egress of mature thymocytes via up-regulation of S1P receptor 1. |
2014 |
Int. Immunol. |
pmid:24343820
|
Setoguchi R |
IL-15 boosts the function and migration of human terminally differentiated CD8+ T cells by inducing a unique gene signature. |
2016 |
Int. Immunol. |
pmid:26857736
|
Maeda Y et al. |
Sphingosine 1-phosphate receptor type 1 regulates egress of mature T cells from mouse bone marrow. |
2010 |
Int. Immunol. |
pmid:20497959
|
Baranowski M et al. |
Ultramarathon run markedly reduces plasma sphingosine-1-phosphate concentration. |
2014 |
Int J Sport Nutr Exerc Metab |
pmid:24092763
|
Masuko K et al. |
Sphingosine-1-phosphate modulates expression of vascular endothelial growth factor in human articular chondrocytes: a possible new role in arthritis. |
2012 |
Int J Rheum Dis |
pmid:22898216
|
Gil-Ortega M et al. |
Ex vivo microperfusion system of the adipose organ: a new approach to studying the mobilization of adipose cell populations. |
2014 |
Int J Obes (Lond) |
pmid:24357852
|
Ueda N |
Ceramide-induced apoptosis in renal tubular cells: a role of mitochondria and sphingosine-1-phoshate. |
2015 |
Int J Mol Sci |
pmid:25751724
|
Smith P et al. |
Sphingosine 1-Phosphate Signaling and Its Pharmacological Modulation in Allogeneic Hematopoietic Stem Cell Transplantation. |
2017 |
Int J Mol Sci |
pmid:28934113
|
Haddadi N et al. |
"Dicing and Splicing" Sphingosine Kinase and Relevance to Cancer. |
2017 |
Int J Mol Sci |
pmid:28869494
|
Egom EE et al. |
Determination of Sphingosine-1-Phosphate in Human Plasma Using Liquid Chromatography Coupled with Q-Tof Mass Spectrometry. |
2017 |
Int J Mol Sci |
pmid:28820460
|
Hajny S and Christoffersen C |
A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation. |
2017 |
Int J Mol Sci |
pmid:28749426
|
Koch A et al. |
Vitamin D Supplementation Enhances C18(dihydro)ceramide Levels in Type 2 Diabetes Patients. |
2017 |
Int J Mol Sci |
pmid:28714882
|
Wollny T et al. |
Sphingosine-1-Phosphate Metabolism and Its Role in the Development of Inflammatory Bowel Disease. |
2017 |
Int J Mol Sci |
pmid:28362332
|
Costello RW et al. |
Mechanism of sphingosine 1-phosphate- and lysophosphatidic acid-induced up-regulation of adhesion molecules and eosinophil chemoattractant in nerve cells. |
2011 |
Int J Mol Sci |
pmid:21686182
|
Tokumura A et al. |
Elevated serum levels of arachidonoyl-lysophosphatidic acid and sphingosine 1-phosphate in systemic sclerosis. |
2009 |
Int J Med Sci |
pmid:19521548
|
Sali M et al. |
Exploiting immunotherapy in Mycobacterium tuberculosis-infected mice: sphingosine 1-phosphate treatment results in a protective or detrimental effect depending on the stage of infection. |
2009 Jan-Mar |
Int J Immunopathol Pharmacol |
pmid:19309565
|
Tian H and Yu Z |
Resveratrol induces apoptosis of leukemia cell line K562 by modulation of sphingosine kinase-1 pathway. |
2015 |
Int J Clin Exp Pathol |
pmid:26045781
|
Pan HY et al. |
Sphingosine-1-phosphate mediates AKT/ERK maintenance of dental pulp homoeostasis. |
2015 |
Int Endod J |
pmid:24931601
|
BÅ‚ogowski W et al. |
Perioperative release of pro-regenerative biochemical signals from human renal allografts subjected to ischemia-reperfusion injury. |
2014 |
Innate Immun |
pmid:23608824
|
Yu H et al. |
Sphingosine kinase 1 improves cutaneous wound healing in diabetic rats. |
2014 |
Injury |
pmid:24685054
|
Ding R et al. |
Sphingosine-1-phosphate attenuates lung injury induced by intestinal ischemia/reperfusion in mice: role of inducible nitric-oxide synthase. |
2012 |
Inflammation |
pmid:21302134
|
Miyabe C et al. |
A sphingosine 1-phosphate receptor agonist ameliorates animal model of vasculitis. |
2017 |
Inflamm. Res. |
pmid:27942751
|
Lv M et al. |
Sphingosine kinase 1/sphingosine-1-phosphate regulates the expression of interleukin-17A in activated microglia in cerebral ischemia/reperfusion. |
2016 |
Inflamm. Res. |
pmid:27002656
|
Seo Y et al. |
Sphingosine-1-phosphate is involved in inflammatory reactions in patients with Graves' orbitopathy. |
2017 |
Inflamm. Res. |
pmid:28364200
|
Farnoud AM et al. |
The Granuloma Response Controlling Cryptococcosis in Mice Depends on the Sphingosine Kinase 1-Sphingosine 1-Phosphate Pathway. |
2015 |
Infect. Immun. |
pmid:25895971
|
Fournie P et al. |
Sphingosine-1 phosphate prevents ethanol-induced corneal epithelial apoptosis. |
2012 Mar-Apr |
Indian J Ophthalmol |
pmid:22446906
|
Sordillo PP et al. |
Review: The Prolonged QT Interval: Role of Pro-inflammatory Cytokines, Reactive Oxygen Species and the Ceramide and Sphingosine-1 Phosphate Pathways. |
|
In Vivo |
pmid:26546519
|
Thamilselvan V et al. |
Sphingosine-1-phosphate stimulates human Caco-2 intestinal epithelial proliferation via p38 activation and activates ERK by an independent mechanism. |
2002 |
In Vitro Cell. Dev. Biol. Anim. |
pmid:12197778
|
Greco E et al. |
Natural lysophospholipids reduce Mycobacterium tuberculosis-induced cytotoxicity and induce anti-mycobacterial activity by a phagolysosome maturation-dependent mechanism in A549 type II alveolar epithelial cells. |
2010 |
Immunology |
pmid:19878354
|
Turner VM and Mabbott NA |
Ageing adversely affects the migration and function of marginal zone B cells. |
2017 |
Immunology |
pmid:28369800
|
Schulz C et al. |
Hematopoietic stem and progenitor cells: their mobilization and homing to bone marrow and peripheral tissue. |
2009 |
Immunol. Res. |
pmid:19340403
|