| MeSH term | MeSH ID | Detail |
|---|---|---|
| Heart Failure | D006333 | 36 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Chemical and Drug Induced Liver Injury | D056486 | 39 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Hyperalgesia | D006930 | 42 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Coronary Artery Disease | D003324 | 47 associated lipids |
Sphingosine 1-phosphate
Sphingosine 1-phosphate is a lipid of Sphingolipids (SP) class. Sphingosine 1-phosphate is associated with abnormalities such as Infection, Painful Bladder Syndrome, Atherosclerosis, Hyperglycemia and Rheumatoid Arthritis. The involved functions are known as Phosphorylation, Regulation, enzyme activity, Energy Absorption and Vascular Permeability. Sphingosine 1-phosphate often locates in Endothelium, Tissue membrane, Vascular System, Protoplasm and Microfilaments. The associated genes with Sphingosine 1-phosphate are MBTPS1 gene, FBXL15 gene, TEK gene, NTRK1 gene and Gene Family. The related lipids are Promega, Lipopolysaccharides, lysophosphatidic acid, Lysophosphatidylcholines and Lysophospholipids. The related experimental models are Knock-out, Mouse Model, Transgenic Model, Disease model and Experimental Autoimmune Encephalomyelitis.
Cross Reference
Introduction
To understand associated biological information of Sphingosine 1-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Sphingosine 1-phosphate?
Sphingosine 1-phosphate is suspected in Lymphopenia, Ischemia, Infection, Atherosclerosis, Multiple Sclerosis, Asthma and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Sphingosine 1-phosphate
PubChem Associated disorders and diseases
What pathways are associated with Sphingosine 1-phosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Sphingosine 1-phosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Sphingosine 1-phosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Sphingosine 1-phosphate?
Knock-out
Knock-out are used in the study 'Sphingosine 1-phosphate-dependent trafficking of peritoneal B cells requires functional NFkappaB-inducing kinase in stromal cells.' (Kunisawa J et al., 2008), Knock-out are used in the study 'Connective tissue growth factor (CTGF/CCN2) mediates angiogenic effect of S1P in human dermal microvascular endothelial cells.' (Markiewicz M et al., 2011), Knock-out are used in the study 'Chasing sphingosine-1-phosphate, a lipid mediator for cardiomyocyte survival.' (Yang Q, 2007), Knock-out are used in the study 'Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function.' (Idzko M et al., 2006) and Knock-out are used in the study 'Platelet endothelial cell adhesion molecule-1 modulates endothelial cell motility through the small G-protein Rho.' (Gratzinger D et al., 2003).
Mouse Model
Mouse Model are used in the study 'Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: role of cortactin.' (Arce FT et al., 2008), Mouse Model are used in the study 'Sequential delivery of vascular endothelial growth factor and sphingosine 1-phosphate for angiogenesis.' (Tengood JE et al., 2010), Mouse Model are used in the study 'S1P(5) is required for sphingosine 1-phosphate-induced autophagy in human prostate cancer PC-3 cells.' (Chang CL et al., 2009), Mouse Model are used in the study 'Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.' (Hughes JE et al., 2008) and Mouse Model are used in the study 'The alliance of sphingosine-1-phosphate and its receptors in immunity.' (Rivera J et al., 2008).
Transgenic Model
Transgenic Model are used in the study 'Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation.' (Augé N et al., 2004), Transgenic Model are used in the study 'Sphingosine-1-phosphate antibodies as potential agents in the treatment of cancer and age-related macular degeneration.' (Sabbadini RA, 2011) and Transgenic Model are used in the study 'Still benched on its way to the bedside: sphingosine kinase 1 as an emerging target in cancer chemotherapy.' (Gault CR and Obeid LM, 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Sphingosine 1-phosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Qin Z et al. | Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary effusion lymphoma. | 2014 | Mol. Cancer Ther. | pmid:24140934 |
| Ryu JM et al. | Sphingosine-1-phosphate-induced Flk-1 transactivation stimulates mouse embryonic stem cell proliferation through S1P1/S1P3-dependent β-arrestin/c-Src pathways. | 2014 | Stem Cell Res | pmid:24145189 |
| Yu Y et al. | Phospholipid transfer protein deficiency decreases the content of S1P in HDL via the loss of its transfer capability. | 2014 | Lipids | pmid:24158769 |
| Giannouli CC et al. | Visualizing S1P-directed cellular egress by intravital imaging. | 2014 | Biochim. Biophys. Acta | pmid:24090699 |
| Zhang Y et al. | Elevated sphingosine-1-phosphate promotes sickling and sickle cell disease progression. | 2014 | J. Clin. Invest. | pmid:24837436 |
| Kurano M et al. | Induction of insulin secretion by apolipoprotein M, a carrier for sphingosine 1-phosphate. | 2014 | Biochim. Biophys. Acta | pmid:24814049 |
| Arya D et al. | Sphingosine-1-phosphate promotes the differentiation of adipose-derived stem cells into endothelial nitric oxide synthase (eNOS) expressing endothelial-like cells. | 2014 | J. Biomed. Sci. | pmid:24898615 |
| Maceyka M and Spiegel S | Sphingolipid metabolites in inflammatory disease. | 2014 | Nature | pmid:24899305 |
| Nagata Y et al. | Sphingosine-1-phosphate mediates epidermal growth factor-induced muscle satellite cell activation. | 2014 | Exp. Cell Res. | pmid:24960577 |
| Brünnert D et al. | Lysophosphatidic acid and sphingosine 1-phosphate metabolic pathways and their receptors are differentially regulated during decidualization of human endometrial stromal cells. | 2014 | Mol. Hum. Reprod. | pmid:24994816 |
| Meng Y et al. | Sphingosine-1-phosphate suppresses cyclophosphamide induced follicle apoptosis in human fetal ovarian xenografts in nude mice. | 2014 | Fertil. Steril. | pmid:24993801 |
| Kang JW and Lee SM | Impaired expression of caveolin-1 contributes to hepatic ischemia and reperfusion injury. | 2014 | Biochem. Biophys. Res. Commun. | pmid:24997335 |
| Nagamatsu T et al. | Emerging roles for lysophospholipid mediators in pregnancy. | 2014 | Am. J. Reprod. Immunol. | pmid:24689547 |
| Shimizu Y et al. | Potentials of the circulating pruritogenic mediator lysophosphatidic acid in development of allergic skin inflammation in mice: role of blood cell-associated lysophospholipase D activity of autotaxin. | 2014 | Am. J. Pathol. | pmid:24641902 |
| Ohotski J et al. | Sphingosine kinase 2 prevents the nuclear translocation of sphingosine 1-phosphate receptor-2 and tyrosine 416 phosphorylated c-Src and increases estrogen receptor negative MDA-MB-231 breast cancer cell growth: The role of sphingosine 1-phosphate receptor-4. | 2014 | Cell. Signal. | pmid:24486401 |
| Takeo T et al. | Investigations of motility and fertilization potential in thawed cryopreserved mouse sperm from cold-stored epididymides. | 2014 | Cryobiology | pmid:24201107 |
| de Assuncao TM et al. | New role for Kruppel-like factor 14 as a transcriptional activator involved in the generation of signaling lipids. | 2014 | J. Biol. Chem. | pmid:24759103 |
| Tibboel J et al. | Sphingolipids in lung growth and repair. | 2014 | Chest | pmid:24394822 |
| Kułakowska A et al. | Increased levels of sphingosine-1-phosphate in cerebrospinal fluid of patients diagnosed with tick-borne encephalitis. | 2014 | J Neuroinflammation | pmid:25421616 |
| Gomes L et al. | Sphingosine 1-phosphate in acute dengue infection. | 2014 | PLoS ONE | pmid:25409037 |
| Xu M et al. | FTY720 inhibits tubulointerstitial inflammation in albumin overload-induced nephropathy of rats via the Sphk1 pathway. | 2014 | Acta Pharmacol. Sin. | pmid:25399649 |
| Watanabe C et al. | Antagonism and synergy of single chain sphingolipids sphingosine and sphingosine-1-phosphate toward lipid bilayer properties. Consequences for their role as cell fate regulators. | 2014 | Langmuir | pmid:25386673 |
| Nakajima C et al. | The lipoprotein receptor LRP1 modulates sphingosine-1-phosphate signaling and is essential for vascular development. | 2014 | Development | pmid:25377550 |
| Barnes J and Dweik RA | Is pulmonary hypertension a metabolic disease? | 2014 | Am. J. Respir. Crit. Care Med. | pmid:25360726 |
| Liu M et al. | Hepatic apolipoprotein M (apoM) overexpression stimulates formation of larger apoM/sphingosine 1-phosphate-enriched plasma high density lipoprotein. | 2014 | J. Biol. Chem. | pmid:24318881 |
| Li F et al. | Sphingosine-1-phosphate prevents chemotherapy-induced human primordial follicle death. | 2014 | Hum. Reprod. | pmid:24221908 |
| Bigaud M et al. | Second generation S1P pathway modulators: research strategies and clinical developments. | 2014 | Biochim. Biophys. Acta | pmid:24239768 |
| Huang YL et al. | Extrinsic sphingosine 1-phosphate activates S1P5 and induces autophagy through generating endoplasmic reticulum stress in human prostate cancer PC-3 cells. | 2014 | Cell. Signal. | pmid:24333325 |
| Emery SM et al. | Combined antiproliferative effects of the aminoalkylindole WIN55,212-2 and radiation in breast cancer cells. | 2014 | J. Pharmacol. Exp. Ther. | pmid:24259678 |
| Sutter I et al. | Apolipoprotein M modulates erythrocyte efflux and tubular reabsorption of sphingosine-1-phosphate. | 2014 | J. Lipid Res. | pmid:24950692 |
| Adamson RH et al. | Albumin modulates S1P delivery from red blood cells in perfused microvessels: mechanism of the protein effect. | 2014 | Am. J. Physiol. Heart Circ. Physiol. | pmid:24531813 |
| Rosen H et al. | The organization of the sphingosine 1-phosphate signaling system. | 2014 | Curr. Top. Microbiol. Immunol. | pmid:24728591 |
| Tan SJ et al. | Targeted anti-apoptosis activity for ovarian protection against chemotherapy-induced ovarian gonadotoxicity. | 2014 | Reprod. Biomed. Online | pmid:25246113 |
| Hanson MA and Peach R | Structural biology of the S1P1 receptor. | 2014 | Curr. Top. Microbiol. Immunol. | pmid:24728592 |
| Cahalan SM | Chemical and genetic tools to explore S1P biology. | 2014 | Curr. Top. Microbiol. Immunol. | pmid:24728593 |
| Goñi FM et al. | Biophysical properties of sphingosine, ceramides and other simple sphingolipids. | 2014 | Biochem. Soc. Trans. | pmid:25233422 |
| Arnon TI and Cyster JG | Blood, sphingosine-1-phosphate and lymphocyte migration dynamics in the spleen. | 2014 | Curr. Top. Microbiol. Immunol. | pmid:24728595 |
| Yagoub D et al. | Sphingosine kinase 1 isoform-specific interactions in breast cancer. | 2014 | Mol. Endocrinol. | pmid:25216046 |
| Yang W et al. | Sphingosine-1-phosphate promotes extravillous trophoblast cell invasion by activating MEK/ERK/MMP-2 signaling pathways via S1P/S1PR1 axis activation. | 2014 | PLoS ONE | pmid:25188412 |
| Chen J et al. | The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertension. | 2014 | Am. J. Respir. Crit. Care Med. | pmid:25180446 |
| Kong Y et al. | Sphingosine-1-phosphate/S1P receptors signaling modulates cell migration in human bone marrow-derived mesenchymal stem cells. | 2014 | Mediators Inflamm. | pmid:25147438 |
| Nagahashi M et al. | Sphingosine-1-phosphate transporters as targets for cancer therapy. | 2014 | Biomed Res Int | pmid:25133174 |
| Tong X et al. | The compensatory enrichment of sphingosine -1- phosphate harbored on glycated high-density lipoprotein restores endothelial protective function in type 2 diabetes mellitus. | 2014 | Cardiovasc Diabetol | pmid:24751283 |
| Murakami M et al. | Controlled release of sphingosine-1-phosphate agonist with gelatin hydrogels for macrophage recruitment. | 2014 | Acta Biomater | pmid:25038462 |
| Park SJ et al. | Sphingosine 1-phosphate induced anti-atherogenic and atheroprotective M2 macrophage polarization through IL-4. | 2014 | Cell. Signal. | pmid:25035231 |
| Kim EY et al. | Role of sphingosine kinase 1 and sphingosine-1-phosphate in CD40 signaling and IgE class switching. | 2014 | FASEB J. | pmid:25002116 |
| Hao J et al. | The interaction between C5a and sphingosine-1-phosphate in neutrophils for antineutrophil cytoplasmic antibody mediated activation. | 2014 | Arthritis Res. Ther. | pmid:25000985 |
| Xiong Y and Hla T | S1P control of endothelial integrity. | 2014 | Curr. Top. Microbiol. Immunol. | pmid:24728594 |
| Mendelson K et al. | Sphingosine 1-phosphate signalling. | 2014 | Development | pmid:24346695 |
| Rauch BH | Sphingosine 1-phosphate as a link between blood coagulation and inflammation. | 2014 | Cell. Physiol. Biochem. | pmid:24977491 |
| Sattler K et al. | HDL-bound sphingosine 1-phosphate (S1P) predicts the severity of coronary artery atherosclerosis. | 2014 | Cell. Physiol. Biochem. | pmid:24977490 |
| Thuy AV et al. | Sphingosine 1-phosphate in blood: function, metabolism, and fate. | 2014 | Cell. Physiol. Biochem. | pmid:24977489 |
| Hait NC et al. | Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory. | 2014 | Nat. Neurosci. | pmid:24859201 |
| van Echten-Deckert G et al. | Sphingosine-1-phosphate: boon and bane for the brain. | 2014 | Cell. Physiol. Biochem. | pmid:24977488 |
| Fayyaz S et al. | Divergent role of sphingosine 1-phosphate on insulin resistance. | 2014 | Cell. Physiol. Biochem. | pmid:24977487 |
| Rahman MM et al. | Sphingosine 1-phosphate induces neutrophil chemoattractant IL-8: repression by steroids. | 2014 | PLoS ONE | pmid:24647471 |
| Poitevin S et al. | Sphingosine kinase 1 expressed by endothelial colony-forming cells has a critical role in their revascularization activity. | 2014 | Cardiovasc. Res. | pmid:24743591 |
| Mahajan-Thakur S et al. | Sphingosine-1-phosphate induces thrombin receptor PAR-4 expression to enhance cell migration and COX-2 formation in human monocytes. | 2014 | J. Leukoc. Biol. | pmid:24990321 |
| O'Sullivan MJ et al. | Sphingosine 1-phosphate (S1P) induced interleukin-8 (IL-8) release is mediated by S1P receptor 2 and nuclear factor κB in BEAS-2B cells. | 2014 | PLoS ONE | pmid:24743449 |
| Jesko H et al. | Sphingosine kinases modulate the secretion of amyloid β precursor protein from SH-SY5Y neuroblastoma cells: the role of α-synuclein. | 2014 | Folia Neuropathol | pmid:24729344 |
| Zhu Y et al. | Vitamin D therapy in experimental allergic encephalomyelitis could be limited by opposing effects of sphingosine 1-phosphate and gelsolin dysregulation. | 2014 | Mol. Neurobiol. | pmid:24722820 |
| Kondo S et al. | Memo has a novel role in S1P signaling and is [corrected] crucial for vascular development. | 2014 | PLoS ONE | pmid:24714781 |
| Korbelik M et al. | Ceramide and sphingosine-1-phosphate act as photodynamic therapy-elicited damage-associated molecular patterns: cell surface exposure. | 2014 | Int. Immunopharmacol. | pmid:24713544 |
| Gatfield J et al. | Sphingosine-1-phosphate (S1P) displays sustained S1P1 receptor agonism and signaling through S1P lyase-dependent receptor recycling. | 2014 | Cell. Signal. | pmid:24704119 |
| Shin KO et al. | Ginsenoside compound K inhibits angiogenesis via regulation of sphingosine kinase-1 in human umbilical vein endothelial cells. | 2014 | Arch. Pharm. Res. | pmid:24687256 |
| Yu H et al. | Sphingosine kinase 1 improves cutaneous wound healing in diabetic rats. | 2014 | Injury | pmid:24685054 |
| Sykes DA et al. | Investigating the molecular mechanisms through which FTY720-P causes persistent S1P1 receptor internalization. | 2014 | Br. J. Pharmacol. | pmid:24641481 |
| Blaho VA and Hla T | An update on the biology of sphingosine 1-phosphate receptors. | 2014 | J. Lipid Res. | pmid:24459205 |
| Chen JJ et al. | Non-genomic rapid responses via progesterone in human peripheral T cells are not indirectly mimicked by sphingosine 1-phosphate. | 2014 | Steroids | pmid:24269742 |
| Whisler JA et al. | Control of perfusable microvascular network morphology using a multiculture microfluidic system. | 2014 | Tissue Eng Part C Methods | pmid:24151838 |
| Mendes-Braz M et al. | The effects of glucose and lipids in steatotic and non-steatotic livers in conditions of partial hepatectomy under ischaemia-reperfusion. | 2014 | Liver Int. | pmid:24107124 |
| Baranowski M et al. | Ultramarathon run markedly reduces plasma sphingosine-1-phosphate concentration. | 2014 | Int J Sport Nutr Exerc Metab | pmid:24092763 |
| Fincher J et al. | G-protein-coupled receptor cell signaling pathways mediating embryonic chick retinal growth cone collapse induced by lysophosphatidic acid and sphingosine-1-phosphate. | 2014 | Dev. Neurosci. | pmid:25138637 |
| Neuber C et al. | Method to simultaneously determine the sphingosine 1-phosphate breakdown product (2E)-hexadecenal and its fatty acid derivatives using isotope-dilution HPLC-electrospray ionization-quadrupole/time-of-flight mass spectrometry. | 2014 | Anal. Chem. | pmid:25137547 |
| Zeng Y et al. | Sphingosine-1-phosphate protects endothelial glycocalyx by inhibiting syndecan-1 shedding. | 2014 | Am. J. Physiol. Heart Circ. Physiol. | pmid:24285115 |
| Speak AO et al. | Altered distribution and function of natural killer cells in murine and human Niemann-Pick disease type C1. | 2014 | Blood | pmid:24235134 |
| Nagahashi M et al. | Sphingosine-1-phosphate in chronic intestinal inflammation and cancer. | 2014 | Adv Biol Regul | pmid:24210073 |
| Ratajczak MZ et al. | The role of sphingosine-1 phosphate and ceramide-1 phosphate in trafficking of normal stem cells and cancer cells. | 2014 | Expert Opin. Ther. Targets | pmid:24188167 |
| Chawla S et al. | Exogenous sphingosine 1-phosphate protects murine splenocytes against hypoxia-induced injury. | 2014 | Lipids | pmid:24190514 |
| Rao PV | Bioactive lysophospholipids: role in regulation of aqueous humor outflow and intraocular pressure in the context of pathobiology and therapy of glaucoma. | 2014 Mar-Apr | J Ocul Pharmacol Ther | pmid:24283588 |
| Potì F et al. | SKI-II--a sphingosine kinase 1 inhibitor--exacerbates atherosclerosis in low-density lipoprotein receptor-deficient (LDL-R-/-) mice on high cholesterol diet. | 2015 | Atherosclerosis | pmid:25801013 |
| Castillo-Badillo JA et al. | α1B-adrenergic receptors differentially associate with Rab proteins during homologous and heterologous desensitization. | 2015 | PLoS ONE | pmid:25799564 |
| Brulhart-Meynet MC et al. | Improving reconstituted HDL composition for efficient post-ischemic reduction of ischemia reperfusion injury. | 2015 | PLoS ONE | pmid:25781943 |
| Li Q et al. | Differential activation of receptors and signal pathways upon stimulation by different doses of sphingosine-1-phosphate in endothelial cells. | 2015 | Exp. Physiol. | pmid:25557733 |
| Borup A et al. | Apolipoprotein M in lipid metabolism and cardiometabolic diseases. | 2015 | Curr. Opin. Lipidol. | pmid:25551802 |
| Moon MH et al. | Activation of S1P2 receptor, a possible mechanism of inhibition of adipogenic differentiation by sphingosine 1‑phosphate. | 2015 | Mol Med Rep | pmid:25351259 |
| Zhang T et al. | Apigenin attenuates heart injury in lipopolysaccharide-induced endotoxemic model by suppressing sphingosine kinase 1/sphingosine 1-phosphate signaling pathway. | 2015 | Chem. Biol. Interact. | pmid:25557508 |
| Liu R et al. | Taurocholate Induces Cyclooxygenase-2 Expression via the Sphingosine 1-phosphate Receptor 2 in a Human Cholangiocarcinoma Cell Line. | 2015 | J. Biol. Chem. | pmid:26518876 |
| Wang Z et al. | Decreased Splenic CD4(+) T-Lymphocytes in Apolipoprotein M Gene Deficient Mice. | 2015 | Biomed Res Int | pmid:26543853 |
| Yu H et al. | Effect of sphingosine-1-phosphate and myoblast transplantation on rat acute myocardial infarction. | 2015 | Genet. Mol. Res. | pmid:26535699 |
| Wang R et al. | Exosome Adherence and Internalization by Hepatic Stellate Cells Triggers Sphingosine 1-Phosphate-dependent Migration. | 2015 | J. Biol. Chem. | pmid:26534962 |
| Klyachkin YM et al. | Pharmacological Elevation of Circulating Bioactive Phosphosphingolipids Enhances Myocardial Recovery After Acute Infarction. | 2015 | Stem Cells Transl Med | pmid:26371341 |
| Zeng Y et al. | Sphingosine 1-phosphate induced synthesis of glycocalyx on endothelial cells. | 2015 | Exp. Cell Res. | pmid:26364737 |
| Choi S et al. | A genetic variant of cortactin linked to acute lung injury impairs lamellipodia dynamics and endothelial wound healing. | 2015 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:26361873 |
| Hsu CK et al. | Mevastatin ameliorates sphingosine 1-phosphate-induced COX-2/PGE2-dependent cell migration via FoxO1 and CREB phosphorylation and translocation. | 2015 | Br. J. Pharmacol. | pmid:26359950 |
| Airola MV et al. | Structural Basis for Ceramide Recognition and Hydrolysis by Human Neutral Ceramidase. | 2015 | Structure | pmid:26190575 |
| Vettorazzi S et al. | Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1. | 2015 | Nat Commun | pmid:26183376 |
| Michels M et al. | Decreased plasma levels of the endothelial protective sphingosine-1-phosphate are associated with dengue-induced plasma leakage. | 2015 | J. Infect. | pmid:26183296 |
| Prager B et al. | Sphingosine 1-phosphate signaling at the blood-brain barrier. | 2015 | Trends Mol Med | pmid:25939882 |
| Rosenberg AJ et al. | A practical process for the preparation of [(32)P]S1P and binding assay for S1P receptor ligands. | 2015 | Appl Radiat Isot | pmid:25931137 |