| MeSH term | MeSH ID | Detail |
|---|---|---|
| Encephalomyelitis, Autoimmune, Experimental | D004681 | 26 associated lipids |
| Rhabdomyosarcoma | D012208 | 7 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Cardiomyopathies | D009202 | 10 associated lipids |
| Shock, Hemorrhagic | D012771 | 4 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Mycobacterium Infections, Nontuberculous | D009165 | 8 associated lipids |
| Vascular Diseases | D014652 | 16 associated lipids |
| Ovarian Diseases | D010049 | 5 associated lipids |
| Anemia | D000740 | 21 associated lipids |
Sphingosine 1-phosphate
Sphingosine 1-phosphate is a lipid of Sphingolipids (SP) class. Sphingosine 1-phosphate is associated with abnormalities such as Infection, Painful Bladder Syndrome, Atherosclerosis, Hyperglycemia and Rheumatoid Arthritis. The involved functions are known as Phosphorylation, Regulation, enzyme activity, Energy Absorption and Vascular Permeability. Sphingosine 1-phosphate often locates in Endothelium, Tissue membrane, Vascular System, Protoplasm and Microfilaments. The associated genes with Sphingosine 1-phosphate are MBTPS1 gene, FBXL15 gene, TEK gene, NTRK1 gene and Gene Family. The related lipids are Promega, Lipopolysaccharides, lysophosphatidic acid, Lysophosphatidylcholines and Lysophospholipids. The related experimental models are Knock-out, Mouse Model, Transgenic Model, Disease model and Experimental Autoimmune Encephalomyelitis.
Cross Reference
Introduction
To understand associated biological information of Sphingosine 1-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Sphingosine 1-phosphate?
Sphingosine 1-phosphate is suspected in Lymphopenia, Ischemia, Infection, Atherosclerosis, Multiple Sclerosis, Asthma and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Sphingosine 1-phosphate
PubChem Associated disorders and diseases
What pathways are associated with Sphingosine 1-phosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Sphingosine 1-phosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Sphingosine 1-phosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Sphingosine 1-phosphate?
Knock-out
Knock-out are used in the study 'Sphingosine 1-phosphate-dependent trafficking of peritoneal B cells requires functional NFkappaB-inducing kinase in stromal cells.' (Kunisawa J et al., 2008), Knock-out are used in the study 'Connective tissue growth factor (CTGF/CCN2) mediates angiogenic effect of S1P in human dermal microvascular endothelial cells.' (Markiewicz M et al., 2011), Knock-out are used in the study 'Chasing sphingosine-1-phosphate, a lipid mediator for cardiomyocyte survival.' (Yang Q, 2007), Knock-out are used in the study 'Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function.' (Idzko M et al., 2006) and Knock-out are used in the study 'Platelet endothelial cell adhesion molecule-1 modulates endothelial cell motility through the small G-protein Rho.' (Gratzinger D et al., 2003).
Mouse Model
Mouse Model are used in the study 'Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: role of cortactin.' (Arce FT et al., 2008), Mouse Model are used in the study 'Sequential delivery of vascular endothelial growth factor and sphingosine 1-phosphate for angiogenesis.' (Tengood JE et al., 2010), Mouse Model are used in the study 'S1P(5) is required for sphingosine 1-phosphate-induced autophagy in human prostate cancer PC-3 cells.' (Chang CL et al., 2009), Mouse Model are used in the study 'Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.' (Hughes JE et al., 2008) and Mouse Model are used in the study 'The alliance of sphingosine-1-phosphate and its receptors in immunity.' (Rivera J et al., 2008).
Transgenic Model
Transgenic Model are used in the study 'Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation.' (Augé N et al., 2004), Transgenic Model are used in the study 'Sphingosine-1-phosphate antibodies as potential agents in the treatment of cancer and age-related macular degeneration.' (Sabbadini RA, 2011) and Transgenic Model are used in the study 'Still benched on its way to the bedside: sphingosine kinase 1 as an emerging target in cancer chemotherapy.' (Gault CR and Obeid LM, 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Sphingosine 1-phosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Theilmeier G et al. | High-density lipoproteins and their constituent, sphingosine-1-phosphate, directly protect the heart against ischemia/reperfusion injury in vivo via the S1P3 lysophospholipid receptor. | 2006 | Circulation | pmid:16982942 |
| Kihara A | [Multifunctional sphingolipid, sphingosine (long-chain base) 1-phosphate: physiological role, metabolism, and intracellular dynamics]. | 2006 | Seikagaku | pmid:16986722 |
| Murph M et al. | Of spiders and crabs: the emergence of lysophospholipids and their metabolic pathways as targets for therapy in cancer. | 2006 | Clin. Cancer Res. | pmid:17121877 |
| Birgbauer E and Chun J | New developments in the biological functions of lysophospholipids. | 2006 | Cell. Mol. Life Sci. | pmid:16988788 |
| Malaplate-Armand C et al. | Soluble oligomers of amyloid-beta peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceramide pathway. | 2006 | Neurobiol. Dis. | pmid:16626961 |
| Hiraga Y et al. | Changes in S1P1 and S1P2 expression during embryonal development and primitive endoderm differentiation of F9 cells. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16631609 |
| French KJ et al. | Antitumor activity of sphingosine kinase inhibitors. | 2006 | J. Pharmacol. Exp. Ther. | pmid:16632640 |
| Wacker BK et al. | Delivery of sphingosine 1-phosphate from poly(ethylene glycol) hydrogels. | 2006 | Biomacromolecules | pmid:16602758 |
| Hemmings DG et al. | Sphingosine-1-phosphate acts via rho-associated kinase and nitric oxide to regulate human placental vascular tone. | 2006 | Biol. Reprod. | pmid:16162874 |
| Schmidt H et al. | LC-MS/MS-analysis of sphingosine-1-phosphate and related compounds in plasma samples. | 2006 | Prostaglandins Other Lipid Mediat. | pmid:17085324 |
| Donati C and Bruni P | Sphingosine 1-phosphate regulates cytoskeleton dynamics: implications in its biological response. | 2006 | Biochim. Biophys. Acta | pmid:16890187 |
| Thompson B et al. | Protein kinase Calpha and sphingosine 1-phosphate-dependent signaling in endothelial cell. | 2006 | Prostaglandins Other Lipid Mediat. | pmid:16846783 |
| Long JS et al. | The functional PDGFbeta receptor-S1P1 receptor signaling complex is involved in regulating migration of mouse embryonic fibroblasts in response to platelet derived growth factor. | 2006 | Prostaglandins Other Lipid Mediat. | pmid:16846788 |
| von Wenckstern H et al. | The role of the lysophospholipid sphingosine 1-phosphate in immune cell biology. | 2006 Jul-Aug | Arch. Immunol. Ther. Exp. (Warsz.) | pmid:16830220 |
| Pan CY et al. | Lysophospholipids regulate excitability and exocytosis in cultured bovine chromaffin cells. | 2007 | J. Neurochem. | pmid:17630986 |
| Tani M et al. | Sphingosine 1-phosphate (S1P) inhibits monocyte-endothelial cell interaction by regulating of RhoA activity. | 2007 | FEBS Lett. | pmid:17825823 |
| Chun J | Immunology. The sources of a lipid conundrum. | 2007 | Science | pmid:17431159 |
| Liao JJ et al. | Distinctive T cell-suppressive signals from nuclearized type 1 sphingosine 1-phosphate G protein-coupled receptors. | 2007 | J. Biol. Chem. | pmid:17121832 |
| Sanchez T et al. | Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN. | 2007 | Arterioscler. Thromb. Vasc. Biol. | pmid:17431187 |
| Jang S et al. | Cytochemical alterations in the rat retina by LPS administration. | 2007 | Neurochem. Res. | pmid:17160463 |
| Harvey KA et al. | Diverse signaling pathways regulate fibroblast differentiation and transformation through Rho kinase activation. | 2007 | J. Cell. Physiol. | pmid:17167780 |
| Blondeau N et al. | Distribution of sphingosine kinase activity and mRNA in rodent brain. | 2007 | J. Neurochem. | pmid:17623044 |
| Giussani P et al. | Sphingosine-1-phosphate and calcium signaling in cerebellar astrocytes and differentiated granule cells. | 2007 | Neurochem. Res. | pmid:17151916 |
| Huwiler A and Zangemeister-Wittke U | Targeting the conversion of ceramide to sphingosine 1-phosphate as a novel strategy for cancer therapy. | 2007 | Crit. Rev. Oncol. Hematol. | pmid:17560117 |
| Pchejetski D et al. | Oxidative stress-dependent sphingosine kinase-1 inhibition mediates monoamine oxidase A-associated cardiac cell apoptosis. | 2007 | Circ. Res. | pmid:17158340 |
| Omori K et al. | Edaravone mimics sphingosine-1-phosphate-induced endothelial barrier enhancement in human microvascular endothelial cells. | 2007 | Am. J. Physiol., Cell Physiol. | pmid:17686998 |
| Keul P et al. | The sphingosine-1-phosphate analogue FTY720 reduces atherosclerosis in apolipoprotein E-deficient mice. | 2007 | Arterioscler. Thromb. Vasc. Biol. | pmid:17158351 |
| Walter DH et al. | Sphingosine-1-phosphate stimulates the functional capacity of progenitor cells by activation of the CXCR4-dependent signaling pathway via the S1P3 receptor. | 2007 | Arterioscler. Thromb. Vasc. Biol. | pmid:17158356 |
| Phan VH et al. | Disruption of sphingolipid metabolism elicits apoptosis-associated reproductive defects in Drosophila. | 2007 | Dev. Biol. | pmid:17706961 |
| Mechtcheriakova D et al. | Sphingosine 1-phosphate phosphatase 2 is induced during inflammatory responses. | 2007 | Cell. Signal. | pmid:17113265 |
| Fujiwara Y et al. | Identification of the hydrophobic ligand binding pocket of the S1P1 receptor. | 2007 | J. Biol. Chem. | pmid:17114791 |
| Ki SH et al. | Galpha12 specifically regulates COX-2 induction by sphingosine 1-phosphate. Role for JNK-dependent ubiquitination and degradation of IkappaBalpha. | 2007 | J. Biol. Chem. | pmid:17098744 |
| Smicun Y et al. | S1P and LPA have an attachment-dependent regulatory effect on invasion of epithelial ovarian cancer cells. | 2007 | Gynecol. Oncol. | pmid:17716713 |
| Chilton L et al. | Evidence of intercellular coupling between co-cultured adult rabbit ventricular myocytes and myofibroblasts. | 2007 | J. Physiol. (Lond.) | pmid:17569734 |
| Barthomeuf C | Inhibition of S1P-induced angiogenesis, metastasis and inflammation by dietary polyphenols. | 2007 | Free Radic. Biol. Med. | pmid:17189837 |
| Currie JC et al. | MT1-MMP down-regulates the glucose 6-phosphate transporter expression in marrow stromal cells: a molecular link between pro-MMP-2 activation, chemotaxis, and cell survival. | 2007 | J. Biol. Chem. | pmid:17229722 |
| Beech DJ | Bipolar phospholipid sensing by TRPC5 calcium channel. | 2007 | Biochem. Soc. Trans. | pmid:17233612 |
| Kunisawa J et al. | Sphingosine 1-phosphate regulates peritoneal B-cell trafficking for subsequent intestinal IgA production. | 2007 | Blood | pmid:17234743 |
| Martino A et al. | Sphingosine 1-phosphate interferes on the differentiation of human monocytes into competent dendritic cells. | 2007 | Scand. J. Immunol. | pmid:17212771 |
| Johnstone ED et al. | Epidermal growth factor and sphingosine-1-phosphate stimulate Na+/H+ exchanger activity in the human placental syncytiotrophoblast. | 2007 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:17913870 |
| Hänel P et al. | Erythrocytes store and release sphingosine 1-phosphate in blood. | 2007 | FASEB J. | pmid:17215483 |
| Gonzalez-Cabrera PJ et al. | Mapping pathways downstream of sphingosine 1-phosphate subtype 1 by differential chemical perturbation and proteomics. | 2007 | J. Biol. Chem. | pmid:17218309 |
| Igarashi J et al. | Statins induce S1P1 receptors and enhance endothelial nitric oxide production in response to high-density lipoproteins. | 2007 | Br. J. Pharmacol. | pmid:17220911 |
| Yang Q | Chasing sphingosine-1-phosphate, a lipid mediator for cardiomyocyte survival. | 2007 | Cardiovasc. Res. | pmid:17331485 |
| Landeen LK et al. | Sphingosine-1-phosphate receptor expression in cardiac fibroblasts is modulated by in vitro culture conditions. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17337593 |
| Maeda Y et al. | Migration of CD4 T cells and dendritic cells toward sphingosine 1-phosphate (S1P) is mediated by different receptor subtypes: S1P regulates the functions of murine mature dendritic cells via S1P receptor type 3. | 2007 | J. Immunol. | pmid:17339438 |
| Serriere-Lanneau V et al. | The sphingosine 1-phosphate receptor S1P2 triggers hepatic wound healing. | 2007 | FASEB J. | pmid:17341687 |
| Means CK et al. | Sphingosine 1-phosphate S1P2 and S1P3 receptor-mediated Akt activation protects against in vivo myocardial ischemia-reperfusion injury. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17293497 |
| Aoki S et al. | The suppressive effect of sphingosine 1-phosphate on monocyte-endothelium adhesion may be mediated by the rearrangement of the endothelial integrins alpha(5)beta(1) and alpha(v)beta(3). | 2007 | J. Thromb. Haemost. | pmid:17403093 |
| Novgorodov AS et al. | Activation of sphingosine-1-phosphate receptor S1P5 inhibits oligodendrocyte progenitor migration. | 2007 | FASEB J. | pmid:17255471 |
| Masuko K et al. | Sphingosine-1-phosphate attenuates proteoglycan aggrecan expression via production of prostaglandin E2 from human articular chondrocytes. | 2007 | BMC Musculoskelet Disord | pmid:17374154 |
| Young N and Van Brocklyn JR | Roles of sphingosine-1-phosphate (S1P) receptors in malignant behavior of glioma cells. Differential effects of S1P2 on cell migration and invasiveness. | 2007 | Exp. Cell Res. | pmid:17376432 |
| Nakamura T et al. | Synthesis and SAR studies of a novel class of S1P1 receptor antagonists. | 2007 | Bioorg. Med. Chem. | pmid:17379528 |
| Zhao Y et al. | Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1. | 2007 | J. Biol. Chem. | pmid:17379599 |
| Sato K et al. | Critical role of ABCA1 transporter in sphingosine 1-phosphate release from astrocytes. | 2007 | J. Neurochem. | pmid:17931360 |
| Nodai A et al. | Sphingosine 1-phosphate induces cyclooxygenase-2 via Ca2+-dependent, but MAPK-independent mechanism in rat vascular smooth muscle cells. | 2007 | Life Sci. | pmid:17382352 |
| Baumruker T et al. | FTY720, an immunomodulatory sphingolipid mimetic: translation of a novel mechanism into clinical benefit in multiple sclerosis. | 2007 | Expert Opin Investig Drugs | pmid:17302523 |
| Baran Y et al. | Alterations of ceramide/sphingosine 1-phosphate rheostat involved in the regulation of resistance to imatinib-induced apoptosis in K562 human chronic myeloid leukemia cells. | 2007 | J. Biol. Chem. | pmid:17303574 |
| Chandru H and Boggaram V | The role of sphingosine 1-phosphate in the TNF-alpha induction of IL-8 gene expression in lung epithelial cells. | 2007 | Gene | pmid:17306937 |
| Jung ID et al. | Sphingosine kinase inhibitor suppresses a Th1 polarization via the inhibition of immunostimulatory activity in murine bone marrow-derived dendritic cells. | 2007 | Int. Immunol. | pmid:17307797 |
| Morales A et al. | Pharmacological inhibition or small interfering RNA targeting acid ceramidase sensitizes hepatoma cells to chemotherapy and reduces tumor growth in vivo. | 2007 | Oncogene | pmid:16862171 |
| Cai Q et al. | Validation of fumonisin biomarkers in F344 rats. | 2007 | Toxicol. Appl. Pharmacol. | pmid:17904604 |
| Molderings GJ et al. | S1P-receptors in PC12 and transfected HEK293 cells: molecular targets of hypotensive imidazoline I(1) receptor ligands. | 2007 | Neurochem. Int. | pmid:17559976 |
| Dyatlovitskaya EV | The role of lysosphingolipids in the regulation of biological processes. | 2007 | Biochemistry Mosc. | pmid:17573701 |
| Baranowski M et al. | PPARalpha agonist induces the accumulation of ceramide in the heart of rats fed high-fat diet. | 2007 | J. Physiol. Pharmacol. | pmid:17440226 |
| Anada Y et al. | The immunomodulator FTY720 is phosphorylated and released from platelets. | 2007 | Eur. J. Pharmacol. | pmid:17553484 |
| Gandolfo MT and Rabb H | Very early alloantigen-independent trafficking of lymphocytes during ischemic acute kidney injury. | 2007 | Kidney Int. | pmid:17554348 |
| Keul P et al. | HDL and its sphingosine-1-phosphate content in cardioprotection. | 2007 | Heart Fail Rev | pmid:17554629 |
| Langlois S et al. | Membrane-type 1 matrix metalloproteinase stimulates cell migration through epidermal growth factor receptor transactivation. | 2007 | Mol. Cancer Res. | pmid:17541067 |
| Sato K et al. | HDL-like lipoproteins in cerebrospinal fluid affect neural cell activity through lipoprotein-associated sphingosine 1-phosphate. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17544365 |
| Levine YC et al. | Agonist-modulated regulation of AMP-activated protein kinase (AMPK) in endothelial cells. Evidence for an AMPK -> Rac1 -> Akt -> endothelial nitric-oxide synthase pathway. | 2007 | J. Biol. Chem. | pmid:17519230 |
| Kimura T et al. | [Measurement of sphingosine 1-phosphate as a biomarker of atherosclerosis]. | 2007 | Rinsho Byori | pmid:17511266 |
| Aoki S et al. | Fluid shear stress enhances the sphingosine 1-phosphate responses in cell-cell interactions between platelets and endothelial cells. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17512899 |
| Huang MC et al. | Th17 augmentation in OTII TCR plus T cell-selective type 1 sphingosine 1-phosphate receptor double transgenic mice. | 2007 | J. Immunol. | pmid:17513728 |
| Kontush A et al. | Preferential sphingosine-1-phosphate enrichment and sphingomyelin depletion are key features of small dense HDL3 particles: relevance to antiapoptotic and antioxidative activities. | 2007 | Arterioscler. Thromb. Vasc. Biol. | pmid:17569880 |
| Rosen H et al. | Tipping the gatekeeper: S1P regulation of endothelial barrier function. | 2007 | Trends Immunol. | pmid:17276731 |
| Liao JJ et al. | Cutting edge: Alternative signaling of Th17 cell development by sphingosine 1-phosphate. | 2007 | J. Immunol. | pmid:17442922 |
| Choi CH et al. | Sphingosine 1-phosphate and sphingosine kinase activity during chicken embryonic development. | 2007 | Arch. Pharm. Res. | pmid:17489368 |
| Donati C et al. | Sphingosine 1-phosphate mediates proliferation and survival of mesoangioblasts. | 2007 | Stem Cells | pmid:17464089 |
| Naor MM et al. | Sphingosine 1-phosphate pKa and binding constants: intramolecular and intermolecular influences. | 2007 | J. Mol. Graph. Model. | pmid:17467317 |
| Ito K et al. | Lack of sphingosine 1-phosphate-degrading enzymes in erythrocytes. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17418101 |
| Iwaki S et al. | Intracellular trafficking pathway of yeast long-chain base kinase Lcb4, from its synthesis to its degradation. | 2007 | J. Biol. Chem. | pmid:17686782 |
| Kim K et al. | Sphingosine 1-phosphate (S1P) induces shape change in rat C6 glioma cells through the S1P2 receptor: development of an agonist for S1P receptors. | 2007 | J. Pharm. Pharmacol. | pmid:17637200 |
| Kurashima Y et al. | Sphingosine 1-phosphate-mediated trafficking of pathogenic Th2 and mast cells for the control of food allergy. | 2007 | J. Immunol. | pmid:17641024 |
| Kawanabe T et al. | Sphingosine 1-phosphate accelerates wound healing in diabetic mice. | 2007 | J. Dermatol. Sci. | pmid:17643267 |
| Brizuela L et al. | Sphingosine-1-phosphate stimulates aldosterone secretion through a mechanism involving the PI3K/PKB and MEK/ERK 1/2 pathways. | 2007 | J. Lipid Res. | pmid:17609523 |
| Jin ZQ et al. | A sphingosine kinase 1 mutation sensitizes the myocardium to ischemia/reperfusion injury. | 2007 | Cardiovasc. Res. | pmid:17610857 |
| Karahatay S et al. | Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma (HNSCC): attenuation of C(18)-ceramide in HNSCC tumors correlates with lymphovascular invasion and nodal metastasis. | 2007 | Cancer Lett. | pmid:17619081 |
| Murph M and Mills GB | Targeting the lipids LPA and S1P and their signalling pathways to inhibit tumour progression. | 2007 | Expert Rev Mol Med | pmid:17935635 |
| Oskeritzian CA et al. | Sphingosine-1-phosphate in allergic responses, asthma and anaphylaxis. | 2007 | Pharmacol. Ther. | pmid:17669501 |
| Xu M et al. | Sphingosine 1-phosphate rapidly increases endothelial barrier function independently of VE-cadherin but requires cell spreading and Rho kinase. | 2007 | Am. J. Physiol., Cell Physiol. | pmid:17670896 |
| Santucci MB et al. | Sphingosine 1-phosphate promotes antigen processing and presentation to CD4+ T cells in Mycobacterium tuberculosis-infected monocytes. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17673170 |
| Tao R et al. | Deletion of the sphingosine kinase-1 gene influences cell fate during hypoxia and glucose deprivation in adult mouse cardiomyocytes. | 2007 | Cardiovasc. Res. | pmid:17320845 |
| Roviezzo F et al. | Sphingosine-1-phosphate/sphingosine kinase pathway is involved in mouse airway hyperresponsiveness. | 2007 | Am. J. Respir. Cell Mol. Biol. | pmid:17322125 |
| Kajimoto T et al. | Involvement of sphingosine-1-phosphate in glutamate secretion in hippocampal neurons. | 2007 | Mol. Cell. Biol. | pmid:17325039 |
| Nombela-Arrieta C et al. | A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate-mediated egress. | 2007 | J. Exp. Med. | pmid:17325199 |
| Osada M et al. | Involvement of sphingosine 1-phosphate, a platelet-derived bioactive lipid, in contraction of mesangium cells. | 2007 | J. Biochem. | pmid:17646176 |
| Furukawa A et al. | Production of nerve growth factor enhanced in cultured mouse astrocytes by glycerophospholipids, sphingolipids, and their related compounds. | 2007 | Mol. Cell. Biochem. | pmid:17577630 |
| Zhu HY and Da WM | [Regulation of immunity by sphingosine 1-phosphate and its G protein-coupled receptors--review]. | 2007 | Zhongguo Shi Yan Xue Ye Xue Za Zhi | pmid:18088493 |
| Igarashi J et al. | Hydrogen peroxide induces S1P1 receptors and sensitizes vascular endothelial cells to sphingosine 1-phosphate, a platelet-derived lipid mediator. | 2007 | Am. J. Physiol., Cell Physiol. | pmid:16943246 |