Radi ZA and Vogel MW |
Gastric parietal cell atrophy and depletion after administration of a sphingosine-1-phosphate 1 inhibitor. |
2014 |
Toxicol Pathol |
pmid:24178572
|
Roviezzo F et al. |
Involvement of proteinase activated receptor-2 in the vascular response to sphingosine 1-phosphate. |
2014 |
Clin. Sci. |
pmid:24131465
|
Qin Z et al. |
Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary effusion lymphoma. |
2014 |
Mol. Cancer Ther. |
pmid:24140934
|
Ryu JM et al. |
Sphingosine-1-phosphate-induced Flk-1 transactivation stimulates mouse embryonic stem cell proliferation through S1P1/S1P3-dependent β-arrestin/c-Src pathways. |
2014 |
Stem Cell Res |
pmid:24145189
|
Yu Y et al. |
Phospholipid transfer protein deficiency decreases the content of S1P in HDL via the loss of its transfer capability. |
2014 |
Lipids |
pmid:24158769
|
Giannouli CC et al. |
Visualizing S1P-directed cellular egress by intravital imaging. |
2014 |
Biochim. Biophys. Acta |
pmid:24090699
|
Zhang Y et al. |
Elevated sphingosine-1-phosphate promotes sickling and sickle cell disease progression. |
2014 |
J. Clin. Invest. |
pmid:24837436
|
Kurano M et al. |
Induction of insulin secretion by apolipoprotein M, a carrier for sphingosine 1-phosphate. |
2014 |
Biochim. Biophys. Acta |
pmid:24814049
|
Arya D et al. |
Sphingosine-1-phosphate promotes the differentiation of adipose-derived stem cells into endothelial nitric oxide synthase (eNOS) expressing endothelial-like cells. |
2014 |
J. Biomed. Sci. |
pmid:24898615
|
Maceyka M and Spiegel S |
Sphingolipid metabolites in inflammatory disease. |
2014 |
Nature |
pmid:24899305
|
Nagata Y et al. |
Sphingosine-1-phosphate mediates epidermal growth factor-induced muscle satellite cell activation. |
2014 |
Exp. Cell Res. |
pmid:24960577
|
Ceccom J et al. |
[Sphingosine 1-phosphate as a biomarker for Alzheimer's disease?]. |
2014 |
Med Sci (Paris) |
pmid:24939530
|
Uhlig S et al. |
Differential regulation of lung endothelial permeability in vitro and in situ. |
2014 |
Cell. Physiol. Biochem. |
pmid:24977477
|
Meng Y et al. |
Sphingosine-1-phosphate suppresses cyclophosphamide induced follicle apoptosis in human fetal ovarian xenografts in nude mice. |
2014 |
Fertil. Steril. |
pmid:24993801
|
Kang JW and Lee SM |
Impaired expression of caveolin-1 contributes to hepatic ischemia and reperfusion injury. |
2014 |
Biochem. Biophys. Res. Commun. |
pmid:24997335
|
Ohotski J et al. |
Sphingosine kinase 2 prevents the nuclear translocation of sphingosine 1-phosphate receptor-2 and tyrosine 416 phosphorylated c-Src and increases estrogen receptor negative MDA-MB-231 breast cancer cell growth: The role of sphingosine 1-phosphate receptor-4. |
2014 |
Cell. Signal. |
pmid:24486401
|
Snider AJ et al. |
Distinct roles for hematopoietic and extra-hematopoietic sphingosine kinase-1 in inflammatory bowel disease. |
2014 |
PLoS ONE |
pmid:25460165
|
Takeo T et al. |
Investigations of motility and fertilization potential in thawed cryopreserved mouse sperm from cold-stored epididymides. |
2014 |
Cryobiology |
pmid:24201107
|
de Assuncao TM et al. |
New role for Kruppel-like factor 14 as a transcriptional activator involved in the generation of signaling lipids. |
2014 |
J. Biol. Chem. |
pmid:24759103
|
Nakanaga K et al. |
Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo. |
2014 |
J. Biochem. |
pmid:24451492
|
Tibboel J et al. |
Sphingolipids in lung growth and repair. |
2014 |
Chest |
pmid:24394822
|
Kim YI et al. |
An endoplasmic reticulum stress-initiated sphingolipid metabolite, ceramide-1-phosphate, regulates epithelial innate immunity by stimulating β-defensin production. |
2014 |
Mol. Cell. Biol. |
pmid:25312644
|
Huang K et al. |
AP-1 regulates sphingosine kinase 1 expression in a positive feedback manner in glomerular mesangial cells exposed to high glucose. |
2014 |
Cell. Signal. |
pmid:24342046
|
Degagné E et al. |
Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs. |
2014 |
J. Clin. Invest. |
pmid:25347472
|
Wang F and Ye P |
Improving heart function by modulating myocardiocyte autophagy: a possible novel mechanism for cardiovascular protection of high-density lipoprotein. |
2014 |
Lipids Health Dis |
pmid:25339382
|
Keller J et al. |
Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts. |
2014 |
Nat Commun |
pmid:25333900
|
Lepletier A et al. |
Early double-negative thymocyte export in Trypanosoma cruzi infection is restricted by sphingosine receptors and associated with human chagas disease. |
2014 |
PLoS Negl Trop Dis |
pmid:25330249
|
Bradley E et al. |
Critical role of Spns2, a sphingosine-1-phosphate transporter, in lung cancer cell survival and migration. |
2014 |
PLoS ONE |
pmid:25330231
|
Xu H et al. |
Sphingosine-1-phosphate receptor agonist, FTY720, restores coronary flow reserve in diabetic rats. |
2014 |
Circ. J. |
pmid:25319164
|
Fukui H et al. |
S1P-Yap1 signaling regulates endoderm formation required for cardiac precursor cell migration in zebrafish. |
2014 |
Dev. Cell |
pmid:25313964
|
Obinata H et al. |
Individual variation of human S1Pâ‚ coding sequence leads to heterogeneity in receptor function and drug interactions. |
2014 |
J. Lipid Res. |
pmid:25293589
|
Fernández-Pisonero I et al. |
Synergy between sphingosine 1-phosphate and lipopolysaccharide signaling promotes an inflammatory, angiogenic and osteogenic response in human aortic valve interstitial cells. |
2014 |
PLoS ONE |
pmid:25275309
|
Sassoli C et al. |
Mesenchymal stromal cell secreted sphingosine 1-phosphate (S1P) exerts a stimulatory effect on skeletal myoblast proliferation. |
2014 |
PLoS ONE |
pmid:25264785
|
Liu M et al. |
Hepatic apolipoprotein M (apoM) overexpression stimulates formation of larger apoM/sphingosine 1-phosphate-enriched plasma high density lipoprotein. |
2014 |
J. Biol. Chem. |
pmid:24318881
|
Silva VR et al. |
Hypothalamic S1P/S1PR1 axis controls energy homeostasis. |
2014 |
Nat Commun |
pmid:25255053
|
Li F et al. |
Sphingosine-1-phosphate prevents chemotherapy-induced human primordial follicle death. |
2014 |
Hum. Reprod. |
pmid:24221908
|
Hirata N et al. |
Sphingosine-1-phosphate promotes expansion of cancer stem cells via S1PR3 by a ligand-independent Notch activation. |
2014 |
Nat Commun |
pmid:25254944
|
Bigaud M et al. |
Second generation S1P pathway modulators: research strategies and clinical developments. |
2014 |
Biochim. Biophys. Acta |
pmid:24239768
|
Iino J et al. |
Platelet-derived sphingosine 1-phosphate induces migration of Jurkat T cells. |
2014 |
Lipids Health Dis |
pmid:25253303
|
Huang YL et al. |
Extrinsic sphingosine 1-phosphate activates S1P5 and induces autophagy through generating endoplasmic reticulum stress in human prostate cancer PC-3 cells. |
2014 |
Cell. Signal. |
pmid:24333325
|
Emery SM et al. |
Combined antiproliferative effects of the aminoalkylindole WIN55,212-2 and radiation in breast cancer cells. |
2014 |
J. Pharmacol. Exp. Ther. |
pmid:24259678
|
Adamson RH et al. |
Albumin modulates S1P delivery from red blood cells in perfused microvessels: mechanism of the protein effect. |
2014 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:24531813
|
Rosen H et al. |
The organization of the sphingosine 1-phosphate signaling system. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728591
|
Hanson MA and Peach R |
Structural biology of the S1P1 receptor. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728592
|
Cahalan SM |
Chemical and genetic tools to explore S1P biology. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728593
|
Arnon TI and Cyster JG |
Blood, sphingosine-1-phosphate and lymphocyte migration dynamics in the spleen. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728595
|
Oldstone MB and Rosen H |
Cytokine storm plays a direct role in the morbidity and mortality from influenza virus infection and is chemically treatable with a single sphingosine-1-phosphate agonist molecule. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728596
|
Martin R and Sospedra M |
Sphingosine-1 phosphate and central nervous system. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728597
|
Deng Y et al. |
Sphingosine Kinase-1/sphingosine 1-phosphate pathway in diabetic nephropathy. |
2014 |
Chin. Med. J. |
pmid:25131242
|
Ogle ME et al. |
Engineering in vivo gradients of sphingosine-1-phosphate receptor ligands for localized microvascular remodeling and inflammatory cell positioning. |
2014 |
Acta Biomater |
pmid:25128750
|
Bi Y et al. |
Sphingosine-1-phosphate mediates a reciprocal signaling pathway between stellate cells and cancer cells that promotes pancreatic cancer growth. |
2014 |
Am. J. Pathol. |
pmid:25111230
|
Ishitsuka A et al. |
FTY720 and cisplatin synergistically induce the death of cisplatin-resistant melanoma cells through the downregulation of the PI3K pathway and the decrease in epidermal growth factor receptor expression. |
2014 |
Int. J. Mol. Med. |
pmid:25109763
|
Xiong H et al. |
SphK1 confers resistance to apoptosis in gastric cancer cells by downregulating Bim via stimulating Akt/FoxO3a signaling. |
2014 |
Oncol. Rep. |
pmid:25109605
|
Rolin J and Maghazachi AA |
Implications of chemokines, chemokine receptors, and inflammatory lipids in atherosclerosis. |
2014 |
J. Leukoc. Biol. |
pmid:24493826
|
Zhao X et al. |
Induction of the matricellular protein CCN1 through RhoA and MRTF-A contributes to ischemic cardioprotection. |
2014 |
J. Mol. Cell. Cardiol. |
pmid:25106095
|
Li MH et al. |
Induction of chemokine (C-C motif) ligand 2 by sphingosine-1-phosphate signaling in neuroblastoma. |
2014 |
J. Pediatr. Surg. |
pmid:25092091
|
Awojoodu AO et al. |
Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to inflammatory microparticle generation in SCD. |
2014 |
Blood |
pmid:25075126
|
Belvitch P et al. |
Proline-rich region of non-muscle myosin light chain kinase modulates kinase activity and endothelial cytoskeletal dynamics. |
2014 |
Microvasc. Res. |
pmid:25072537
|
Mendes-da-Cruz DA et al. |
Semaphorin 3F and neuropilin-2 control the migration of human T-cell precursors. |
2014 |
PLoS ONE |
pmid:25068647
|
Moon MH et al. |
Sphingosine-1-phosphate inhibits the adipogenic differentiation of 3T3-L1 preadipocytes. |
2014 |
Int. J. Mol. Med. |
pmid:25050633
|
Tong X et al. |
The compensatory enrichment of sphingosine -1- phosphate harbored on glycated high-density lipoprotein restores endothelial protective function in type 2 diabetes mellitus. |
2014 |
Cardiovasc Diabetol |
pmid:24751283
|
Xiong Y and Hla T |
S1P control of endothelial integrity. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728594
|
Mendelson K et al. |
Sphingosine 1-phosphate signalling. |
2014 |
Development |
pmid:24346695
|
Hait NC et al. |
Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory. |
2014 |
Nat. Neurosci. |
pmid:24859201
|
Rahman MM et al. |
Sphingosine 1-phosphate induces neutrophil chemoattractant IL-8: repression by steroids. |
2014 |
PLoS ONE |
pmid:24647471
|
Park SM et al. |
Sphingosine-1-phosphate lyase is expressed by CD68+ cells on the parenchymal side of marginal reticular cells in human lymph nodes. |
2014 |
Eur. J. Immunol. |
pmid:24825162
|
Simmons S and Ishii M |
Sphingosine-1-phosphate: a master regulator of lymphocyte egress and immunity. |
2014 |
Arch. Immunol. Ther. Exp. (Warsz.) |
pmid:24276789
|
Don AS et al. |
Re-configuration of sphingolipid metabolism by oncogenic transformation. |
2014 |
Biomolecules |
pmid:24970218
|
Snelder N et al. |
Translational pharmacokinetic modeling of fingolimod (FTY720) as a paradigm compound subject to sphingosine kinase-mediated phosphorylation. |
2014 |
Drug Metab. Dispos. |
pmid:24965813
|
Tarbell JM et al. |
Mechanosensing at the vascular interface. |
2014 |
Annu Rev Biomed Eng |
pmid:24905872
|
Potì F et al. |
Atheroprotective role of high-density lipoprotein (HDL)-associated sphingosine-1-phosphate (S1P). |
2014 |
Cardiovasc. Res. |
pmid:24891400
|
Chawla S et al. |
Exogenous sphingosine-1-phosphate boosts acclimatization in rats exposed to acute hypobaric hypoxia: assessment of haematological and metabolic effects. |
2014 |
PLoS ONE |
pmid:24887065
|
Janes K et al. |
The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1. |
2014 |
J. Biol. Chem. |
pmid:24876379
|
Yan W et al. |
Adiponectin regulates SR Ca(2+) cycling following ischemia/reperfusion via sphingosine 1-phosphate-CaMKII signaling in mice. |
2014 |
J. Mol. Cell. Cardiol. |
pmid:24852843
|
Sheridan GK and Dev KK |
Targeting S1P receptors in experimental autoimmune encephalomyelitis in mice improves early deficits in locomotor activity and increases ultrasonic vocalisations. |
2014 |
Sci Rep |
pmid:24851861
|
Ni X et al. |
Interaction of integrin β4 with S1P receptors in S1P- and HGF-induced endothelial barrier enhancement. |
2014 |
J. Cell. Biochem. |
pmid:24851274
|
Vanoli E et al. |
Vagomimetic effects of fingolimod: physiology and clinical implications. |
2014 |
CNS Neurosci Ther |
pmid:24836740
|
Zhang GQ et al. |
Sphingosine-1-phosphate receptors respond differently to early myocardial ischemia and ischemia-reperfusion in vivo. |
2014 |
Sheng Li Xue Bao |
pmid:24777407
|
Ceglarek U et al. |
Preanalytical standardization of sphingosine-1-phosphate, sphinganine-1-phosphate and sphingosine analysis in human plasma by liquid chromatography-tandem mass spectrometry. |
2014 |
Clin. Chim. Acta |
pmid:24768784
|
Smyth SS et al. |
Arguing the case for the autotaxin-lysophosphatidic acid-lipid phosphate phosphatase 3-signaling nexus in the development and complications of atherosclerosis. |
2014 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:24482375
|
Priceman SJ et al. |
S1PR1 is crucial for accumulation of regulatory T cells in tumors via STAT3. |
2014 |
Cell Rep |
pmid:24630990
|
Oizumi A et al. |
Pseudomonas-derived ceramidase induces production of inflammatory mediators from human keratinocytes via sphingosine-1-phosphate. |
2014 |
PLoS ONE |
pmid:24586752
|
Guan Z et al. |
Sphingosine-1-phosphate evokes unique segment-specific vasoconstriction of the renal microvasculature. |
2014 |
J. Am. Soc. Nephrol. |
pmid:24578134
|
Takabe K and Spiegel S |
Export of sphingosine-1-phosphate and cancer progression. |
2014 |
J. Lipid Res. |
pmid:24474820
|
Ishizawa S et al. |
Sphingosine-1-phosphate induces differentiation of cultured renal tubular epithelial cells under Rho kinase activation via the S1P2 receptor. |
2014 |
Clin. Exp. Nephrol. |
pmid:24463961
|
Couttas TA et al. |
Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer's disease pathogenesis. |
2014 |
Acta Neuropathol Commun |
pmid:24456642
|
Gassowska M et al. |
Sphingosine kinases/sphingosine-1-phosphate and death Signalling in APP-transfected cells. |
2014 |
Neurochem. Res. |
pmid:24452756
|
Borge M et al. |
The expression of sphingosine-1 phosphate receptor-1 in chronic lymphocytic leukemia cells is impaired by tumor microenvironmental signals and enhanced by piceatannol and R406. |
2014 |
J. Immunol. |
pmid:25127862
|
Fujii K et al. |
Sphingosine 1-phosphate increases an intracellular Ca(2+) concentration via S1P3 receptor in cultured vascular smooth muscle cells. |
2014 |
J. Pharm. Pharmacol. |
pmid:24450400
|
Ito S et al. |
TNF-α production in NKT cell hybridoma is regulated by sphingosine-1-phosphate: implications for inflammation in atherosclerosis. |
2014 |
Coron. Artery Dis. |
pmid:24448174
|
Czubowicz K and Strosznajder R |
Ceramide in the molecular mechanisms of neuronal cell death. The role of sphingosine-1-phosphate. |
2014 |
Mol. Neurobiol. |
pmid:24420784
|
Kerage D et al. |
Review: novel insights into the regulation of vascular tone by sphingosine 1-phosphate. |
2014 |
Placenta |
pmid:24411702
|
Gil-Ortega M et al. |
Ex vivo microperfusion system of the adipose organ: a new approach to studying the mobilization of adipose cell populations. |
2014 |
Int J Obes (Lond) |
pmid:24357852
|
Abu El-Asrar AM et al. |
Expression of bioactive lysophospholipids and processing enzymes in the vitreous from patients with proliferative diabetic retinopathy. |
2014 |
Lipids Health Dis |
pmid:25496321
|
Cencetti F et al. |
Lysophosphatidic acid stimulates cell migration of satellite cells. A role for the sphingosine kinase/sphingosine 1-phosphate axis. |
2014 |
FEBS J. |
pmid:25131845
|
Zeng Y et al. |
Sphingosine-1-phosphate protects endothelial glycocalyx by inhibiting syndecan-1 shedding. |
2014 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:24285115
|
Speak AO et al. |
Altered distribution and function of natural killer cells in murine and human Niemann-Pick disease type C1. |
2014 |
Blood |
pmid:24235134
|
Nagahashi M et al. |
Sphingosine-1-phosphate in chronic intestinal inflammation and cancer. |
2014 |
Adv Biol Regul |
pmid:24210073
|
Ratajczak MZ et al. |
The role of sphingosine-1 phosphate and ceramide-1 phosphate in trafficking of normal stem cells and cancer cells. |
2014 |
Expert Opin. Ther. Targets |
pmid:24188167
|
Chawla S et al. |
Exogenous sphingosine 1-phosphate protects murine splenocytes against hypoxia-induced injury. |
2014 |
Lipids |
pmid:24190514
|