| MeSH term | MeSH ID | Detail |
|---|---|---|
| Encephalomyelitis, Autoimmune, Experimental | D004681 | 26 associated lipids |
| Rhabdomyosarcoma | D012208 | 7 associated lipids |
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Cardiomyopathies | D009202 | 10 associated lipids |
| Shock, Hemorrhagic | D012771 | 4 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Mycobacterium Infections, Nontuberculous | D009165 | 8 associated lipids |
| Vascular Diseases | D014652 | 16 associated lipids |
| Ovarian Diseases | D010049 | 5 associated lipids |
| Anemia | D000740 | 21 associated lipids |
Sphingosine 1-phosphate
Sphingosine 1-phosphate is a lipid of Sphingolipids (SP) class. Sphingosine 1-phosphate is associated with abnormalities such as Infection, Painful Bladder Syndrome, Atherosclerosis, Hyperglycemia and Rheumatoid Arthritis. The involved functions are known as Phosphorylation, Regulation, enzyme activity, Energy Absorption and Vascular Permeability. Sphingosine 1-phosphate often locates in Endothelium, Tissue membrane, Vascular System, Protoplasm and Microfilaments. The associated genes with Sphingosine 1-phosphate are MBTPS1 gene, FBXL15 gene, TEK gene, NTRK1 gene and Gene Family. The related lipids are Promega, Lipopolysaccharides, lysophosphatidic acid, Lysophosphatidylcholines and Lysophospholipids. The related experimental models are Knock-out, Mouse Model, Transgenic Model, Disease model and Experimental Autoimmune Encephalomyelitis.
Cross Reference
Introduction
To understand associated biological information of Sphingosine 1-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Sphingosine 1-phosphate?
Sphingosine 1-phosphate is suspected in Lymphopenia, Ischemia, Infection, Atherosclerosis, Multiple Sclerosis, Asthma and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Sphingosine 1-phosphate
PubChem Associated disorders and diseases
What pathways are associated with Sphingosine 1-phosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Sphingosine 1-phosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Sphingosine 1-phosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Sphingosine 1-phosphate?
Knock-out
Knock-out are used in the study 'Sphingosine 1-phosphate-dependent trafficking of peritoneal B cells requires functional NFkappaB-inducing kinase in stromal cells.' (Kunisawa J et al., 2008), Knock-out are used in the study 'Connective tissue growth factor (CTGF/CCN2) mediates angiogenic effect of S1P in human dermal microvascular endothelial cells.' (Markiewicz M et al., 2011), Knock-out are used in the study 'Chasing sphingosine-1-phosphate, a lipid mediator for cardiomyocyte survival.' (Yang Q, 2007), Knock-out are used in the study 'Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function.' (Idzko M et al., 2006) and Knock-out are used in the study 'Platelet endothelial cell adhesion molecule-1 modulates endothelial cell motility through the small G-protein Rho.' (Gratzinger D et al., 2003).
Mouse Model
Mouse Model are used in the study 'Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: role of cortactin.' (Arce FT et al., 2008), Mouse Model are used in the study 'Sequential delivery of vascular endothelial growth factor and sphingosine 1-phosphate for angiogenesis.' (Tengood JE et al., 2010), Mouse Model are used in the study 'S1P(5) is required for sphingosine 1-phosphate-induced autophagy in human prostate cancer PC-3 cells.' (Chang CL et al., 2009), Mouse Model are used in the study 'Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.' (Hughes JE et al., 2008) and Mouse Model are used in the study 'The alliance of sphingosine-1-phosphate and its receptors in immunity.' (Rivera J et al., 2008).
Transgenic Model
Transgenic Model are used in the study 'Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation.' (Augé N et al., 2004), Transgenic Model are used in the study 'Sphingosine-1-phosphate antibodies as potential agents in the treatment of cancer and age-related macular degeneration.' (Sabbadini RA, 2011) and Transgenic Model are used in the study 'Still benched on its way to the bedside: sphingosine kinase 1 as an emerging target in cancer chemotherapy.' (Gault CR and Obeid LM, 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Sphingosine 1-phosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wetter JA et al. | Utilization of the Tango beta-arrestin recruitment technology for cell-based EDG receptor assay development and interrogation. | 2009 | J Biomol Screen | pmid:19726785 |
| Li C et al. | Involvement of sphingosine 1-phosphate (SIP)/S1P3 signaling in cholestasis-induced liver fibrosis. | 2009 | Am. J. Pathol. | pmid:19729475 |
| Hait NC et al. | Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate. | 2009 | Science | pmid:19729656 |
| De Luca T et al. | Downstream targets of altered sphingolipid metabolism in response to inhibition of ENOX2 by phenoxodiol. | 2008 | Biofactors | pmid:19734127 |
| Park SW et al. | Sphinganine-1-phosphate attenuates both hepatic and renal injury induced by hepatic ischemia and reperfusion in mice. | 2010 | Shock | pmid:19752779 |
| Zhao J et al. | Phosphotyrosine protein dynamics in cell membrane rafts of sphingosine-1-phosphate-stimulated human endothelium: role in barrier enhancement. | 2009 | Cell. Signal. | pmid:19755153 |
| Xu Y et al. | Lipid generation and signaling in ovarian cancer. | 2009 | Cancer Treat. Res. | pmid:19763440 |
| Wang F and Fishman DA | Lysophosphatidic acid and invasion. | 2009 | Cancer Treat. Res. | pmid:19763441 |
| Mochizuki N | [Discovery of S1P transporter may uncover the unidentified S1P-regulated signal in circulation, immunity, and bone metabolism]. | 2009 | Tanpakushitsu Kakusan Koso | pmid:19764473 |
| Brakch N et al. | Evidence for a role of sphingosine-1 phosphate in cardiovascular remodelling in Fabry disease. | 2010 | Eur. Heart J. | pmid:19773225 |
| Crousillac S et al. | Sphingosine-1-phosphate elicits receptor-dependent calcium signaling in retinal amacrine cells. | 2009 | J. Neurophysiol. | pmid:19776367 |
| Long DA and Price KL | Sphingosine kinase-1: a potential mediator of renal fibrosis. | 2009 | Kidney Int. | pmid:19789541 |
| Rhee S et al. | Promigratory and procontractile growth factor environments differentially regulate cell morphogenesis. | 2010 | Exp. Cell Res. | pmid:19796636 |
| Hla T | Plugging vascular leak by sphingosine kinase from bone marrow progenitor cells. | 2009 | Circ. Res. | pmid:19797192 |
| Abrahan CE et al. | Synthesis of sphingosine is essential for oxidative stress-induced apoptosis of photoreceptors. | 2010 | Invest. Ophthalmol. Vis. Sci. | pmid:19797232 |
| Gratschev D et al. | Sphingosine kinase as a regulator of calcium entry through autocrine sphingosine 1-phosphate signaling in thyroid FRTL-5 cells. | 2009 | Endocrinology | pmid:19797403 |
| Xiang Y et al. | Discovery of novel sphingosine kinase 1 inhibitors. | 2009 | Bioorg. Med. Chem. Lett. | pmid:19800228 |
| Tachikawa M et al. | Lysophospholipids enhance taurine release from rat retinal vascular endothelial cells under hypoosmotic stress. | 2009 | Microvasc. Res. | pmid:19804786 |
| Coelho RP et al. | Sphingosine-1-phosphate and oligodendrocytes: from cell development to the treatment of multiple sclerosis. | 2010 | Prostaglandins Other Lipid Mediat. | pmid:19808013 |
| Jenne CN et al. | T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow. | 2009 | J. Exp. Med. | pmid:19808259 |
| Brinkmann V | FTY720 (fingolimod) in Multiple Sclerosis: therapeutic effects in the immune and the central nervous system. | 2009 | Br. J. Pharmacol. | pmid:19814729 |
| Wojciak JM et al. | The crystal structure of sphingosine-1-phosphate in complex with a Fab fragment reveals metal bridging of an antibody and its antigen. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19815502 |
| Morris AJ et al. | Blood relatives: dynamic regulation of bioactive lysophosphatidic acid and sphingosine-1-phosphate metabolism in the circulation. | 2009 | Trends Cardiovasc. Med. | pmid:19818950 |
| Jacobson JR | Pharmacologic therapies on the horizon for acute lung injury/acute respiratory distress syndrome. | 2009 | J. Investig. Med. | pmid:19820408 |
| Rolin J et al. | FTY720 and SEW2871 reverse the inhibitory effect of S1P on natural killer cell mediated lysis of K562 tumor cells and dendritic cells but not on cytokine release. | 2010 | Cancer Immunol. Immunother. | pmid:19823820 |
| Mochizuki N | Vascular integrity mediated by vascular endothelial cadherin and regulated by sphingosine 1-phosphate and angiopoietin-1. | 2009 | Circ. J. | pmid:19838001 |
| Malchinkhuu E et al. | Role of Rap1B and tumor suppressor PTEN in the negative regulation of lysophosphatidic acid--induced migration by isoproterenol in glioma cells. | 2009 | Mol. Biol. Cell | pmid:19864456 |
| Heo K et al. | Sphingosine 1-phosphate induces vascular endothelial growth factor expression in endothelial cells. | 2009 | BMB Rep | pmid:19874715 |
| Greco E et al. | Natural lysophospholipids reduce Mycobacterium tuberculosis-induced cytotoxicity and induce anti-mycobacterial activity by a phagolysosome maturation-dependent mechanism in A549 type II alveolar epithelial cells. | 2010 | Immunology | pmid:19878354 |
| Haghikia A and Gold R | Sphingosine-1-phosphate and its receptors as a possible therapeutic target in autoimmune diseases of the nervous system. | 2010 | J. Neuroimmunol. | pmid:19879005 |
| Espinosa Cervantes R | [Sphingolipids in embryonic implantation]. | 2009 | Ginecol Obstet Mex | pmid:19899433 |
| Hancke K et al. | Ovarian transplantation for fertility preservation in a sheep model: can follicle loss be prevented by antiapoptotic sphingosine-1-phosphate administration? | 2009 | Gynecol. Endocrinol. | pmid:19906004 |
| Claas RF et al. | Enhanced Ca2+ storage in sphingosine-1-phosphate lyase-deficient fibroblasts. | 2010 | Cell. Signal. | pmid:19913094 |
| Serra M and Saba JD | Sphingosine 1-phosphate lyase, a key regulator of sphingosine 1-phosphate signaling and function. | 2010 | Adv. Enzyme Regul. | pmid:19914275 |
| Chen JH et al. | Sphingosine kinase regulates oxidized low density lipoprotein-mediated calcium oscillations and macrophage survival. | 2010 | J. Lipid Res. | pmid:19965613 |
| Diab KJ et al. | Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema. | 2010 | Am. J. Respir. Crit. Care Med. | pmid:19965812 |
| Yamamoto Y et al. | Increased expression of enzymes for sphingosine 1-phosphate turnover and signaling in human decidua during late pregnancy. | 2010 | Biol. Reprod. | pmid:20007411 |
| Wang S et al. | A polysaccharide, MDG-1, induces S1P1 and bFGF expression and augments survival and angiogenesis in the ischemic heart. | 2010 | Glycobiology | pmid:20008963 |
| McDonald RA et al. | The sphingosine kinase inhibitor N,N-dimethylsphingosine inhibits neointimal hyperplasia. | 2010 | Br. J. Pharmacol. | pmid:20015089 |
| Pham TH et al. | Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning. | 2010 | J. Exp. Med. | pmid:20026661 |
| Nayak D et al. | Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia. | 2010 | Neuroscience | pmid:20036321 |
| Ling B et al. | Sphingosine-1-phosphate: a potential therapeutic agent against human breast cancer. | 2011 | Invest New Drugs | pmid:20041340 |
| Danieli-Betto D et al. | Sphingosine 1-phosphate signaling is involved in skeletal muscle regeneration. | 2010 | Am. J. Physiol., Cell Physiol. | pmid:20042733 |
| Agudo-López A et al. | Involvement of mitochondria on neuroprotective effect of sphingosine-1-phosphate in cell death in an in vitro model of brain ischemia. | 2010 | Neurosci. Lett. | pmid:20045720 |
| Riccio A | New endogenous regulators of class I histone deacetylases. | 2010 | Sci Signal | pmid:20051592 |
| Brown M et al. | Quantitative distribution and colocalization of non-muscle myosin light chain kinase isoforms and cortactin in human lung endothelium. | 2010 | Microvasc. Res. | pmid:20053363 |
| Tao R et al. | High-density lipoprotein determines adult mouse cardiomyocyte fate after hypoxia-reoxygenation through lipoprotein-associated sphingosine 1-phosphate. | 2010 | Am. J. Physiol. Heart Circ. Physiol. | pmid:20061542 |
| Nam JH et al. | Ca2+ signaling induced by sphingosine 1-phosphate and lysophosphatidic acid in mouse B cells. | 2010 | Mol. Cells | pmid:20069383 |
| Fletcher JI et al. | ABC transporters in cancer: more than just drug efflux pumps. | 2010 | Nat. Rev. Cancer | pmid:20075923 |
| Egom EE et al. | Cardioprotection in ischemia/reperfusion injury: spotlight on sphingosine-1-phosphate and bradykinin signalling. | 2010 | Prog. Biophys. Mol. Biol. | pmid:20080123 |
| Shea BS et al. | Prolonged exposure to sphingosine 1-phosphate receptor-1 agonists exacerbates vascular leak, fibrosis, and mortality after lung injury. | 2010 | Am. J. Respir. Cell Mol. Biol. | pmid:20081052 |
| Hannoun A et al. | Addition of sphingosine-1-phosphate to human oocyte culture medium decreases embryo fragmentation. | 2010 | Reprod. Biomed. Online | pmid:20093086 |
| Murakami A et al. | Sphingosine 1-phosphate (S1P) regulates vascular contraction via S1P3 receptor: investigation based on a new S1P3 receptor antagonist. | 2010 | Mol. Pharmacol. | pmid:20097776 |
| Bektas M et al. | Sphingosine 1-phosphate lyase deficiency disrupts lipid homeostasis in liver. | 2010 | J. Biol. Chem. | pmid:20097939 |
| Incorvaia C et al. | Anaphylaxis: an update on its understanding and management. | 2010 | Recent Pat Inflamm Allergy Drug Discov | pmid:20100165 |
| Dunlap KA et al. | The sphingosine 1-phosphate (S1P) signaling pathway is regulated during pregnancy in sheep. | 2010 | Biol. Reprod. | pmid:20107206 |
| Takabe K et al. | Estradiol induces export of sphingosine 1-phosphate from breast cancer cells via ABCC1 and ABCG2. | 2010 | J. Biol. Chem. | pmid:20110355 |
| Aydin M et al. | The sphingosine-1-phosphate pathway is upregulated in response to partial urethral obstruction in male rats and activates RhoA/Rho-kinase signalling. | 2010 | BJU Int. | pmid:20128782 |
| Leong WI and Saba JD | S1P metabolism in cancer and other pathological conditions. | 2010 | Biochimie | pmid:20167244 |
| Pereira JP et al. | A role for S1P and S1P1 in immature-B cell egress from mouse bone marrow. | 2010 | PLoS ONE | pmid:20174580 |
| Yu XQ et al. | Pharmacokinetic/pharmacodynamic modelling of 2-acetyl-4(5)-tetrahydroxybutyl imidazole-induced peripheral lymphocyte sequestration through increasing lymphoid sphingosine 1-phosphate. | 2010 | Xenobiotica | pmid:20175664 |
| Bode C et al. | Erythrocytes serve as a reservoir for cellular and extracellular sphingosine 1-phosphate. | 2010 | J. Cell. Biochem. | pmid:20186882 |
| Okae H and Iwakura Y | Neural tube defects and impaired neural progenitor cell proliferation in Gbeta1-deficient mice. | 2010 | Dev. Dyn. | pmid:20186915 |
| Ikeda H et al. | Plasma concentration of bioactive lipid mediator sphingosine 1-phosphate is reduced in patients with chronic hepatitis C. | 2010 | Clin. Chim. Acta | pmid:20188085 |
| Ma B et al. | Stereochemistry-activity relationship of orally active tetralin S1P agonist prodrugs. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20188554 |
| Gangoiti P et al. | Control of metabolism and signaling of simple bioactive sphingolipids: Implications in disease. | 2010 | Prog. Lipid Res. | pmid:20193711 |
| Tölle M et al. | Relevance of sphingolipids in the pleiotropic protective effects of high-density lipoproteins. | 2010 | Curr. Pharm. Des. | pmid:20196741 |
| Weigert A et al. | Cleavage of sphingosine kinase 2 by caspase-1 provokes its release from apoptotic cells. | 2010 | Blood | pmid:20197547 |
| Vessey DA et al. | Pannexin-I/P2X 7 purinergic receptor channels mediate the release of cardioprotectants induced by ischemic pre- and postconditioning. | 2010 | J. Cardiovasc. Pharmacol. Ther. | pmid:20200324 |
| Lee H et al. | Bone marrow-derived mesenchymal stem cells prevent the loss of Niemann-Pick type C mouse Purkinje neurons by correcting sphingolipid metabolism and increasing sphingosine-1-phosphate. | 2010 | Stem Cells | pmid:20201063 |
| Qi X et al. | Sustained delivery of sphingosine-1-phosphate using poly(lactic-co-glycolic acid)-based microparticles stimulates Akt/ERK-eNOS mediated angiogenesis and vascular maturation restoring blood flow in ischemic limbs of mice. | 2010 | Eur. J. Pharmacol. | pmid:20206620 |
| Xu R et al. | Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes. | 2010 | FASEB J. | pmid:20207939 |
| Morishige J et al. | A clean-up technology for the simultaneous determination of lysophosphatidic acid and sphingosine-1-phosphate by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry using a phosphate-capture molecule, Phos-tag. | 2010 | Rapid Commun. Mass Spectrom. | pmid:20213695 |
| Qin J et al. | Neurons and oligodendrocytes recycle sphingosine 1-phosphate to ceramide: significance for apoptosis and multiple sclerosis. | 2010 | J. Biol. Chem. | pmid:20215115 |
| Sensken SC et al. | Redistribution of sphingosine 1-phosphate by sphingosine kinase 2 contributes to lymphopenia. | 2010 | J. Immunol. | pmid:20220090 |
| Kim M et al. | Isoflurane protects human kidney proximal tubule cells against necrosis via sphingosine kinase and sphingosine-1-phosphate generation. | 2010 | Am. J. Nephrol. | pmid:20234131 |
| Suhaiman L et al. | Sphingosine 1-phosphate and sphingosine kinase are involved in a novel signaling pathway leading to acrosomal exocytosis. | 2010 | J. Biol. Chem. | pmid:20236935 |
| Martin R | Multiple sclerosis: closing in on an oral treatment. | 2010 | Nature | pmid:20237554 |
| Di A et al. | A novel function of sphingosine kinase 1 suppression of JNK activity in preventing inflammation and injury. | 2010 | J. Biol. Chem. | pmid:20299461 |
| Cuvillier O et al. | Activation of sphingosine kinase-1 in cancer: implications for therapeutic targeting. | 2010 | Curr Mol Pharmacol | pmid:20302564 |
| Evindar G et al. | Exploration of amino alcohol derivatives as novel, potent, and highly selective sphingosine-1-phosphate receptor subtype-1 agonists. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20304639 |
| Malemud CJ | The discovery of novel experimental therapies for inflammatory arthritis. | 2009 | Mediators Inflamm. | pmid:20339519 |
| Lan T et al. | Determination of sphingosine kinase activity in biological samples by liquid chromatography-tandem mass spectrometry. | 2010 | Biomed. Chromatogr. | pmid:20352614 |
| Ratajczak MZ et al. | Novel insight into stem cell mobilization-plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex. | 2010 | Leukemia | pmid:20357827 |
| Alford SK et al. | Prediction of sphingosine 1-phosphate-stimulated endothelial cell migration rates using biochemical measurements. | 2010 | Ann Biomed Eng | pmid:20358290 |
| Förster A et al. | Glucocorticoids protect renal mesangial cells from apoptosis by increasing cellular sphingosine-1-phosphate. | 2010 | Kidney Int. | pmid:20375982 |
| Sun HY et al. | Sphingosine-1-phosphate induces human endothelial VEGF and MMP-2 production via transcription factor ZNF580: novel insights into angiogenesis. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20382120 |
| Siow DL et al. | Intracellular localization of sphingosine kinase 1 alters access to substrate pools but does not affect the degradative fate of sphingosine-1-phosphate. | 2010 | J. Lipid Res. | pmid:20386061 |
| Hu WM et al. | Effect of S1P5 on proliferation and migration of human esophageal cancer cells. | 2010 | World J. Gastroenterol. | pmid:20397263 |
| Harvey KA et al. | Role of Rho kinase in sphingosine 1-phosphate-mediated endothelial and smooth muscle cell migration and differentiation. | 2010 | Mol. Cell. Biochem. | pmid:20401628 |
| Tawa H et al. | Role of afadin in vascular endothelial growth factor- and sphingosine 1-phosphate-induced angiogenesis. | 2010 | Circ. Res. | pmid:20413783 |
| Hoofnagle AN et al. | HDL lipids and insulin resistance. | 2010 | Curr. Diab. Rep. | pmid:20425071 |
| Yoshida T et al. | Therapeutic angiogenesis by implantation of a capillary structure constituted of human adipose tissue microvascular endothelial cells. | 2010 | Arterioscler. Thromb. Vasc. Biol. | pmid:20431071 |
| Shayman JA | The riddle of the sphinx redux. | 2010 | Kidney Int. | pmid:20431574 |
| Kułakowska A et al. | Intrathecal increase of sphingosine 1-phosphate at early stage multiple sclerosis. | 2010 | Neurosci. Lett. | pmid:20434523 |
| Szczepaniak WS et al. | S1P2 receptor-dependent Rho-kinase activation mediates vasoconstriction in the murine pulmonary circulation induced by sphingosine 1-phosphate. | 2010 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:20435688 |
| Bolli MH et al. | 2-imino-thiazolidin-4-one derivatives as potent, orally active S1P1 receptor agonists. | 2010 | J. Med. Chem. | pmid:20446681 |
| Norman E et al. | Plasma membrane sphingomyelin hydrolysis increases hippocampal neuron excitability by sphingosine-1-phosphate mediated mechanisms. | 2010 | J. Neurochem. | pmid:20456020 |
| Cao C et al. | The efficacy of activated protein C in murine endotoxemia is dependent on integrin CD11b. | 2010 | J. Clin. Invest. | pmid:20458145 |
| Park SW et al. | Sphinganine-1-phosphate protects kidney and liver after hepatic ischemia and reperfusion in mice through S1P1 receptor activation. | 2010 | Lab. Invest. | pmid:20458275 |