Radi ZA and Vogel MW |
Gastric parietal cell atrophy and depletion after administration of a sphingosine-1-phosphate 1 inhibitor. |
2014 |
Toxicol Pathol |
pmid:24178572
|
Che W et al. |
Corticosteroids inhibit sphingosine 1-phosphate-induced interleukin-6 secretion from human airway smooth muscle via mitogen-activated protein kinase phosphatase 1-mediated repression of mitogen and stress-activated protein kinase 1. |
2014 |
Am. J. Respir. Cell Mol. Biol. |
pmid:24032470
|
Chang N et al. |
Sphingosine 1-phosphate receptors negatively regulate collagen type I/III expression in human bone marrow-derived mesenchymal stem cell. |
2014 |
J. Cell. Biochem. |
pmid:24038457
|
Völzke A et al. |
Sphingosine 1-phosphate (S1P) induces COX-2 expression and PGE2 formation via S1P receptor 2 in renal mesangial cells. |
2014 |
Biochim. Biophys. Acta |
pmid:24064301
|
Pyne NJ et al. |
The role of sphingosine 1-phosphate in inflammation and cancer. |
2014 |
Adv Biol Regul |
pmid:24070975
|
Nguyen-Tran DH et al. |
Molecular mechanism of sphingosine-1-phosphate action in Duchenne muscular dystrophy. |
2014 |
Dis Model Mech |
pmid:24077965
|
Tanaka K et al. |
Anti-interleukin-6 receptor antibody prevents systemic bone mass loss via reducing the number of osteoclast precursors in bone marrow in a collagen-induced arthritis model. |
2014 |
Clin. Exp. Immunol. |
pmid:24028747
|
Kihara A |
Sphingosine 1-phosphate is a key metabolite linking sphingolipids to glycerophospholipids. |
2014 |
Biochim. Biophys. Acta |
pmid:23994042
|
Moxon JV et al. |
Comparison of the serum lipidome in patients with abdominal aortic aneurysm and peripheral artery disease. |
2014 |
Circ Cardiovasc Genet |
pmid:24448739
|
Gorlino CV et al. |
Neutrophils exhibit differential requirements for homing molecules in their lymphatic and blood trafficking into draining lymph nodes. |
2014 |
J. Immunol. |
pmid:25015824
|
Anderson G and Maes M |
Reconceptualizing adult neurogenesis: role for sphingosine-1-phosphate and fibroblast growth factor-1 in co-ordinating astrocyte-neuronal precursor interactions. |
2014 |
CNS Neurol Disord Drug Targets |
pmid:24040808
|
Waeber C and Walther T |
Sphingosine-1-phosphate as a potential target for the treatment of myocardial infarction. |
2014 |
Circ. J. |
pmid:24632793
|
Brünnert D et al. |
Lysophosphatidic acid and sphingosine 1-phosphate metabolic pathways and their receptors are differentially regulated during decidualization of human endometrial stromal cells. |
2014 |
Mol. Hum. Reprod. |
pmid:24994816
|
Nagamatsu T et al. |
Emerging roles for lysophospholipid mediators in pregnancy. |
2014 |
Am. J. Reprod. Immunol. |
pmid:24689547
|
Shimizu Y et al. |
Potentials of the circulating pruritogenic mediator lysophosphatidic acid in development of allergic skin inflammation in mice: role of blood cell-associated lysophospholipase D activity of autotaxin. |
2014 |
Am. J. Pathol. |
pmid:24641902
|
Snider AJ et al. |
Distinct roles for hematopoietic and extra-hematopoietic sphingosine kinase-1 in inflammatory bowel disease. |
2014 |
PLoS ONE |
pmid:25460165
|
Huang K et al. |
AP-1 regulates sphingosine kinase 1 expression in a positive feedback manner in glomerular mesangial cells exposed to high glucose. |
2014 |
Cell. Signal. |
pmid:24342046
|
Slattum G et al. |
Autophagy in oncogenic K-Ras promotes basal extrusion of epithelial cells by degrading S1P. |
2014 |
Curr. Biol. |
pmid:24361067
|
Miller DS |
Sphingolipid signaling reduces basal P-glycoprotein activity in renal proximal tubule. |
2014 |
J. Pharmacol. Exp. Ther. |
pmid:24385389
|
Dai L et al. |
Sphingosine 1-phosphate: a potential molecular target for ovarian cancer therapy? |
2014 |
Cancer Invest. |
pmid:24499107
|
Ito K et al. |
Integrin α9 on lymphatic endothelial cells regulates lymphocyte egress. |
2014 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:24516133
|
Nakajima C et al. |
The lipoprotein receptor LRP1 modulates sphingosine-1-phosphate signaling and is essential for vascular development. |
2014 |
Development |
pmid:25377550
|
Takeshita E et al. |
Diacylglycerol kinase γ is a novel anionic phospholipid binding protein with a selective binding preference. |
2014 |
Biochem. Biophys. Res. Commun. |
pmid:24486543
|
Barnes J and Dweik RA |
Is pulmonary hypertension a metabolic disease? |
2014 |
Am. J. Respir. Crit. Care Med. |
pmid:25360726
|
Kamiya T et al. |
Role of Ca2+ -dependent and Ca2+ -sensitive mechanisms in sphingosine 1-phosphate-induced constriction of isolated porcine retinal arterioles in vitro. |
2014 |
Exp. Eye Res. |
pmid:24486793
|
Plano D et al. |
Importance of sphingosine kinase (SphK) as a target in developing cancer therapeutics and recent developments in the synthesis of novel SphK inhibitors. |
2014 |
J. Med. Chem. |
pmid:24471412
|
Nakamura H and Murayama T |
Role of sphingolipids in arachidonic acid metabolism. |
2014 |
J. Pharmacol. Sci. |
pmid:24599139
|
Guo S et al. |
Higher level of plasma bioactive molecule sphingosine 1-phosphate in women is associated with estrogen. |
2014 |
Biochim. Biophys. Acta |
pmid:24603322
|
Kempf A et al. |
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. |
2014 |
PLoS Biol. |
pmid:24453941
|
Sutter I et al. |
Apolipoprotein M modulates erythrocyte efflux and tubular reabsorption of sphingosine-1-phosphate. |
2014 |
J. Lipid Res. |
pmid:24950692
|
Xiong Y et al. |
Erythrocyte-derived sphingosine 1-phosphate is essential for vascular development. |
2014 |
J. Clin. Invest. |
pmid:25250575
|
Tan SJ et al. |
Targeted anti-apoptosis activity for ovarian protection against chemotherapy-induced ovarian gonadotoxicity. |
2014 |
Reprod. Biomed. Online |
pmid:25246113
|
Goñi FM et al. |
Biophysical properties of sphingosine, ceramides and other simple sphingolipids. |
2014 |
Biochem. Soc. Trans. |
pmid:25233422
|
Yagoub D et al. |
Sphingosine kinase 1 isoform-specific interactions in breast cancer. |
2014 |
Mol. Endocrinol. |
pmid:25216046
|
Yang W et al. |
Sphingosine-1-phosphate promotes extravillous trophoblast cell invasion by activating MEK/ERK/MMP-2 signaling pathways via S1P/S1PR1 axis activation. |
2014 |
PLoS ONE |
pmid:25188412
|
Martin R and Sospedra M |
Sphingosine-1 phosphate and central nervous system. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728597
|
Chen J et al. |
The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertension. |
2014 |
Am. J. Respir. Crit. Care Med. |
pmid:25180446
|
Kong Y et al. |
Sphingosine-1-phosphate/S1P receptors signaling modulates cell migration in human bone marrow-derived mesenchymal stem cells. |
2014 |
Mediators Inflamm. |
pmid:25147438
|
Shayegi N et al. |
CXCR4 blockade and sphingosine-1-phosphate activation facilitate engraftment of haematopoietic stem and progenitor cells in a non-myeloablative transplant model. |
2014 |
Br. J. Haematol. |
pmid:24180707
|
Nagahashi M et al. |
Sphingosine-1-phosphate transporters as targets for cancer therapy. |
2014 |
Biomed Res Int |
pmid:25133174
|
Kim ES et al. |
Inflammatory lipid sphingosine-1-phosphate upregulates C-reactive protein via C/EBPβ and potentiates breast cancer progression. |
2014 |
Oncogene |
pmid:23955082
|
St John AL et al. |
S1P-Dependent trafficking of intracellular yersinia pestis through lymph nodes establishes Buboes and systemic infection. |
2014 |
Immunity |
pmid:25238098
|
Davis KM and Isberg RR |
Plague's partners in crime. |
2014 |
Immunity |
pmid:25238090
|
Fuerst E et al. |
Sphingosine-1-phosphate induces pro-remodelling response in airway smooth muscle cells. |
2014 |
Allergy |
pmid:25041788
|
Murakami M et al. |
Controlled release of sphingosine-1-phosphate agonist with gelatin hydrogels for macrophage recruitment. |
2014 |
Acta Biomater |
pmid:25038462
|
Park SJ et al. |
Sphingosine 1-phosphate induced anti-atherogenic and atheroprotective M2 macrophage polarization through IL-4. |
2014 |
Cell. Signal. |
pmid:25035231
|
Kim EY et al. |
Role of sphingosine kinase 1 and sphingosine-1-phosphate in CD40 signaling and IgE class switching. |
2014 |
FASEB J. |
pmid:25002116
|
Schwalm S et al. |
Targeting the sphingosine kinase/sphingosine 1-phosphate pathway to treat chronic inflammatory kidney diseases. |
2014 |
Basic Clin. Pharmacol. Toxicol. |
pmid:23789924
|
Hao J et al. |
The interaction between C5a and sphingosine-1-phosphate in neutrophils for antineutrophil cytoplasmic antibody mediated activation. |
2014 |
Arthritis Res. Ther. |
pmid:25000985
|
Tsai YC et al. |
Antiapoptotic agent sphingosine-1-phosphate protects vitrified murine ovarian grafts. |
2014 |
Reprod Sci |
pmid:23793475
|
Rauch BH |
Sphingosine 1-phosphate as a link between blood coagulation and inflammation. |
2014 |
Cell. Physiol. Biochem. |
pmid:24977491
|
Sattler K et al. |
HDL-bound sphingosine 1-phosphate (S1P) predicts the severity of coronary artery atherosclerosis. |
2014 |
Cell. Physiol. Biochem. |
pmid:24977490
|
Thuy AV et al. |
Sphingosine 1-phosphate in blood: function, metabolism, and fate. |
2014 |
Cell. Physiol. Biochem. |
pmid:24977489
|
van Echten-Deckert G et al. |
Sphingosine-1-phosphate: boon and bane for the brain. |
2014 |
Cell. Physiol. Biochem. |
pmid:24977488
|
Fayyaz S et al. |
Divergent role of sphingosine 1-phosphate on insulin resistance. |
2014 |
Cell. Physiol. Biochem. |
pmid:24977487
|
Simmons S and Ishii M |
Sphingosine-1-phosphate: a master regulator of lymphocyte egress and immunity. |
2014 |
Arch. Immunol. Ther. Exp. (Warsz.) |
pmid:24276789
|
Poitevin S et al. |
Sphingosine kinase 1 expressed by endothelial colony-forming cells has a critical role in their revascularization activity. |
2014 |
Cardiovasc. Res. |
pmid:24743591
|
Mahajan-Thakur S et al. |
Sphingosine-1-phosphate induces thrombin receptor PAR-4 expression to enhance cell migration and COX-2 formation in human monocytes. |
2014 |
J. Leukoc. Biol. |
pmid:24990321
|
O'Sullivan MJ et al. |
Sphingosine 1-phosphate (S1P) induced interleukin-8 (IL-8) release is mediated by S1P receptor 2 and nuclear factor κB in BEAS-2B cells. |
2014 |
PLoS ONE |
pmid:24743449
|
Jesko H et al. |
Sphingosine kinases modulate the secretion of amyloid β precursor protein from SH-SY5Y neuroblastoma cells: the role of α-synuclein. |
2014 |
Folia Neuropathol |
pmid:24729344
|
Zhu Y et al. |
Vitamin D therapy in experimental allergic encephalomyelitis could be limited by opposing effects of sphingosine 1-phosphate and gelsolin dysregulation. |
2014 |
Mol. Neurobiol. |
pmid:24722820
|
Kondo S et al. |
Memo has a novel role in S1P signaling and is [corrected] crucial for vascular development. |
2014 |
PLoS ONE |
pmid:24714781
|
Korbelik M et al. |
Ceramide and sphingosine-1-phosphate act as photodynamic therapy-elicited damage-associated molecular patterns: cell surface exposure. |
2014 |
Int. Immunopharmacol. |
pmid:24713544
|
Gatfield J et al. |
Sphingosine-1-phosphate (S1P) displays sustained S1P1 receptor agonism and signaling through S1P lyase-dependent receptor recycling. |
2014 |
Cell. Signal. |
pmid:24704119
|
Shin KO et al. |
Ginsenoside compound K inhibits angiogenesis via regulation of sphingosine kinase-1 in human umbilical vein endothelial cells. |
2014 |
Arch. Pharm. Res. |
pmid:24687256
|
Yu H et al. |
Sphingosine kinase 1 improves cutaneous wound healing in diabetic rats. |
2014 |
Injury |
pmid:24685054
|
Sykes DA et al. |
Investigating the molecular mechanisms through which FTY720-P causes persistent S1P1 receptor internalization. |
2014 |
Br. J. Pharmacol. |
pmid:24641481
|
Blaho VA and Hla T |
An update on the biology of sphingosine 1-phosphate receptors. |
2014 |
J. Lipid Res. |
pmid:24459205
|
Shen Z et al. |
Sphingosine 1-phosphate (S1P) promotes mitochondrial biogenesis in Hep G2 cells by activating Peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α). |
2014 |
Cell Stress Chaperones |
pmid:24293320
|
Chen JJ et al. |
Non-genomic rapid responses via progesterone in human peripheral T cells are not indirectly mimicked by sphingosine 1-phosphate. |
2014 |
Steroids |
pmid:24269742
|
Whisler JA et al. |
Control of perfusable microvascular network morphology using a multiculture microfluidic system. |
2014 |
Tissue Eng Part C Methods |
pmid:24151838
|
Mendes-Braz M et al. |
The effects of glucose and lipids in steatotic and non-steatotic livers in conditions of partial hepatectomy under ischaemia-reperfusion. |
2014 |
Liver Int. |
pmid:24107124
|
Baranowski M et al. |
Ultramarathon run markedly reduces plasma sphingosine-1-phosphate concentration. |
2014 |
Int J Sport Nutr Exerc Metab |
pmid:24092763
|
Abu El-Asrar AM et al. |
Expression of bioactive lysophospholipids and processing enzymes in the vitreous from patients with proliferative diabetic retinopathy. |
2014 |
Lipids Health Dis |
pmid:25496321
|
Jensen T et al. |
The identification of GPR3 inverse agonist AF64394; the first small molecule inhibitor of GPR3 receptor function. |
2014 |
Bioorg. Med. Chem. Lett. |
pmid:25442311
|
Ye C et al. |
Identification of a novel small-molecule agonist for human G protein-coupled receptor 3. |
2014 |
J. Pharmacol. Exp. Ther. |
pmid:24633425
|
Pyszko J and Strosznajder JB |
Sphingosine kinase 1 and sphingosine-1-phosphate in oxidative stress evoked by 1-methyl-4-phenylpyridinium (MPP+) in human dopaminergic neuronal cells. |
2014 |
Mol. Neurobiol. |
pmid:24399507
|
Fincher J et al. |
G-protein-coupled receptor cell signaling pathways mediating embryonic chick retinal growth cone collapse induced by lysophosphatidic acid and sphingosine-1-phosphate. |
2014 |
Dev. Neurosci. |
pmid:25138637
|
Neuber C et al. |
Method to simultaneously determine the sphingosine 1-phosphate breakdown product (2E)-hexadecenal and its fatty acid derivatives using isotope-dilution HPLC-electrospray ionization-quadrupole/time-of-flight mass spectrometry. |
2014 |
Anal. Chem. |
pmid:25137547
|
Rao PV |
Bioactive lysophospholipids: role in regulation of aqueous humor outflow and intraocular pressure in the context of pathobiology and therapy of glaucoma. |
2014 Mar-Apr |
J Ocul Pharmacol Ther |
pmid:24283588
|
Pulli I et al. |
A novel chimeric aequorin fused with caveolin-1 reveals a sphingosine kinase 1-regulated Ca²⺠microdomain in the caveolar compartment. |
2015 |
Biochim. Biophys. Acta |
pmid:25892494
|
Zankov DP and Ogita H |
Actin-tethered junctional complexes in angiogenesis and lymphangiogenesis in association with vascular endothelial growth factor. |
2015 |
Biomed Res Int |
pmid:25883953
|
Williams PA et al. |
Hypoxia augments outgrowth endothelial cell (OEC) sprouting and directed migration in response to sphingosine-1-phosphate (S1P). |
2015 |
PLoS ONE |
pmid:25875493
|
Schröder M et al. |
Subcellular distribution of FTY720 and FTY720-phosphate in immune cells - another aspect of Fingolimod action relevant for therapeutic application. |
2015 |
Biol. Chem. |
pmid:25720062
|
Koch A et al. |
Downregulation of sphingosine 1-phosphate (S1P) receptor 1 by dexamethasone inhibits S1P-induced mesangial cell migration. |
2015 |
Biol. Chem. |
pmid:25719311
|
Park ES et al. |
Tumor necrosis factor (TNF) receptor-associated factor (TRAF)-interacting protein (TRIP) negatively regulates the TRAF2 ubiquitin-dependent pathway by suppressing the TRAF2-sphingosine 1-phosphate (S1P) interaction. |
2015 |
J. Biol. Chem. |
pmid:25716317
|
Rhee SH et al. |
Pelvic organ prolapse is associated with alteration of sphingosine-1-phosphate/Rho-kinase signalling pathway in human vaginal wall. |
2015 |
J Obstet Gynaecol |
pmid:25692679
|
Roviezzo F et al. |
S1P-induced airway smooth muscle hyperresponsiveness and lung inflammation in vivo: molecular and cellular mechanisms. |
2015 |
Br. J. Pharmacol. |
pmid:25439580
|
Carroll B et al. |
Sphingolipids in the DNA damage response. |
2015 |
Adv Biol Regul |
pmid:25434743
|
Xiu L et al. |
Intracellular sphingosine 1-phosphate contributes to collagen expression of hepatic myofibroblasts in human liver fibrosis independent of its receptors. |
2015 |
Am. J. Pathol. |
pmid:25432063
|
Moon MH et al. |
Activation of S1P2 receptor, a possible mechanism of inhibition of adipogenic differentiation by sphingosine 1‑phosphate. |
2015 |
Mol Med Rep |
pmid:25351259
|
Iwabuchi K et al. |
Role of Ceramide from Glycosphingolipids and Its Metabolites in Immunological and Inflammatory Responses in Humans. |
2015 |
Mediators Inflamm. |
pmid:26609196
|
Jeong JK et al. |
Modulation of the expression of sphingosine 1-phosphate 2 receptors regulates the differentiation of pre-adipocytes. |
2015 |
Mol Med Rep |
pmid:26459774
|
Li C et al. |
Sphingosine 1-phosphate enhances the excitability of rat sensory neurons through activation of sphingosine 1-phosphate receptors 1 and/or 3. |
2015 |
J Neuroinflammation |
pmid:25880547
|
Adamiak M et al. |
Evidence for the involvement of sphingosine-1-phosphate in the homing and engraftment of hematopoietic stem cells to bone marrow. |
2015 |
Oncotarget |
pmid:26299919
|
Mori H et al. |
Smad3 deficiency leads to mandibular condyle degradation via the sphingosine 1-phosphate (S1P)/S1P3 signaling axis. |
2015 |
Am. J. Pathol. |
pmid:26272361
|
Chen MH et al. |
Identification of SPHK1 as a therapeutic target and marker of poor prognosis in cholangiocarcinoma. |
2015 |
Oncotarget |
pmid:26090720
|
Panneer Selvam S et al. |
Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. |
2015 |
Sci Signal |
pmid:26082434
|
Malik FA et al. |
Sphingosine-1-Phosphate Is a Novel Regulator of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity. |
2015 |
PLoS ONE |
pmid:26079370
|
Mooren OL et al. |
Role of N-WASP in Endothelial Monolayer Formation and Integrity. |
2015 |
J. Biol. Chem. |
pmid:26070569
|