Jo SK et al. |
Divergent roles of sphingosine kinases in kidney ischemia-reperfusion injury. |
2009 |
Kidney Int. |
pmid:18971925
|
Wang L and Dudek SM |
Regulation of vascular permeability by sphingosine 1-phosphate. |
2009 |
Microvasc. Res. |
pmid:18973762
|
Sun X et al. |
Enhanced interaction between focal adhesion and adherens junction proteins: involvement in sphingosine 1-phosphate-induced endothelial barrier enhancement. |
2009 |
Microvasc. Res. |
pmid:19323978
|
Beech DJ et al. |
TRPC channel lipid specificity and mechanisms of lipid regulation. |
2009 |
Cell Calcium |
pmid:19324410
|
Hernandez F et al. |
Local effects of the sphingosine 1-phosphate on prostaglandin F2alpha-induced luteolysis in the pregnant rat. |
2009 |
Mol. Reprod. Dev. |
pmid:19645054
|
Igarashi J et al. |
Transforming growth factor-beta1 downregulates caveolin-1 expression and enhances sphingosine 1-phosphate signaling in cultured vascular endothelial cells. |
2009 |
Am. J. Physiol., Cell Physiol. |
pmid:19710365
|
Stamer WD et al. |
Sphingosine-1-phosphate effects on the inner wall of Schlemm's canal and outflow facility in perfused human eyes. |
2009 |
Exp. Eye Res. |
pmid:19715693
|
Morris AJ et al. |
Regulation of blood and vascular cell function by bioactive lysophospholipids. |
2009 |
J. Thromb. Haemost. |
pmid:19630765
|
Li C et al. |
Involvement of sphingosine 1-phosphate (SIP)/S1P3 signaling in cholestasis-induced liver fibrosis. |
2009 |
Am. J. Pathol. |
pmid:19729475
|
Hait NC et al. |
Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate. |
2009 |
Science |
pmid:19729656
|
Czech B et al. |
The immunomodulatory sphingosine 1-phosphate analog FTY720 reduces lesion size and improves neurological outcome in a mouse model of cerebral ischemia. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19720050
|
GarcÃa-Pacios M et al. |
Sphingosine-1-phosphate as an amphipathic metabolite: its properties in aqueous and membrane environments. |
2009 |
Biophys. J. |
pmid:19720028
|
Vogel P et al. |
Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions. |
2009 |
PLoS ONE |
pmid:19119317
|
Roztocil E et al. |
Mechanisms of sphingosine-1-phosphate-induced akt-dependent smooth muscle cell migration. |
2009 |
Surgery |
pmid:19081473
|
Evindar G et al. |
Synthesis and evaluation of alkoxy-phenylamides and alkoxy-phenylimidazoles as potent sphingosine-1-phosphate receptor subtype-1 agonists. |
2009 |
Bioorg. Med. Chem. Lett. |
pmid:19081720
|
Lagadari M et al. |
Sphingosine-1-phosphate inhibits the cytotoxic activity of NK cells via Gs protein-mediated signalling. |
2009 |
Int. J. Oncol. |
pmid:19082500
|
Natsume H et al. |
(-)-Epigallocatechin gallate attenuates the induction of HSP27 stimulated by sphingosine 1-phosphate via suppression of phosphatidylinositol 3-kinase/Akt pathway in osteoblasts. |
2009 |
Int. J. Mol. Med. |
pmid:19578793
|
Jung ID et al. |
FcepsilonRI-mediated mast cell migration: signaling pathways and dependence on cytosolic free Ca2+ concentration. |
2009 |
Cell. Signal. |
pmid:19632319
|
Martin JL et al. |
Potentiation of growth factor signaling by insulin-like growth factor-binding protein-3 in breast epithelial cells requires sphingosine kinase activity. |
2009 |
J. Biol. Chem. |
pmid:19633297
|
Trifilieff A et al. |
Role of sphingosine-1-phosphate (S1P) and the S1P(2) receptor in allergen-induced, mast cell-dependent contraction of rat lung parenchymal strips. |
2009 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:19636535
|
Wacker BK et al. |
Hypoxic preconditioning-induced cerebral ischemic tolerance: role of microvascular sphingosine kinase 2. |
2009 |
Stroke |
pmid:19644058
|
Vessey DA et al. |
Sphingosine 1-phosphate is an important endogenous cardioprotectant released by ischemic pre- and postconditioning. |
2009 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:19648253
|
Ohno Y et al. |
Palmitoylation of the sphingosine 1-phosphate receptor S1P is involved in its signaling functions and internalization. |
2009 |
Genes Cells |
pmid:19619245
|
Greenspon J et al. |
Sphingosine-1-phosphate protects intestinal epithelial cells from apoptosis through the Akt signaling pathway. |
2009 |
Dig. Dis. Sci. |
pmid:18654850
|
Malemud CJ |
The discovery of novel experimental therapies for inflammatory arthritis. |
2009 |
Mediators Inflamm. |
pmid:20339519
|
Xie B et al. |
Blockade of sphingosine-1-phosphate reduces macrophage influx and retinal and choroidal neovascularization. |
2009 |
J. Cell. Physiol. |
pmid:18781584
|
Camerer E et al. |
Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice. |
2009 |
J. Clin. Invest. |
pmid:19603543
|
Pyne S et al. |
Role of sphingosine kinases and lipid phosphate phosphatases in regulating spatial sphingosine 1-phosphate signalling in health and disease. |
2009 |
Cell. Signal. |
pmid:18768158
|
Snider AJ et al. |
A role for sphingosine kinase 1 in dextran sulfate sodium-induced colitis. |
2009 |
FASEB J. |
pmid:18815359
|
Hla T and Im DS |
Cell biology. The ABCs of lipophile transport. |
2009 |
Science |
pmid:19213902
|
Thathiah A et al. |
The orphan G protein-coupled receptor 3 modulates amyloid-beta peptide generation in neurons. |
2009 |
Science |
pmid:19213921
|
Gaengel K et al. |
Endothelial-mural cell signaling in vascular development and angiogenesis. |
2009 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:19164813
|
Benamer N et al. |
Molecular and functional characterization of a new potassium conductance in mouse ventricular fibroblasts. |
2009 |
J. Mol. Cell. Cardiol. |
pmid:19166858
|
Wadgaonkar R et al. |
Differential regulation of sphingosine kinases 1 and 2 in lung injury. |
2009 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:19168577
|
Reines I et al. |
Topical application of sphingosine-1-phosphate and FTY720 attenuate allergic contact dermatitis reaction through inhibition of dendritic cell migration. |
2009 |
J. Invest. Dermatol. |
pmid:19194476
|
Kim RH et al. |
Export and functions of sphingosine-1-phosphate. |
2009 |
Biochim. Biophys. Acta |
pmid:19268560
|
Herr B et al. |
The supernatant of apoptotic cells causes transcriptional activation of hypoxia-inducible factor-1alpha in macrophages via sphingosine-1-phosphate and transforming growth factor-beta. |
2009 |
Blood |
pmid:19549990
|
Limaye V |
The role of sphingosine kinase and sphingosine-1-phosphate in the regulation of endothelial cell biology. |
2008 May-Jun |
Endothelium |
pmid:18568950
|
Vessey DA et al. |
Sphingosine can pre- and post-condition heart and utilizes a different mechanism from sphingosine 1-phosphate. |
2008 Mar-Apr |
J. Biochem. Mol. Toxicol. |
pmid:18418901
|
Won J and Lee GH |
T-cell-targeted signaling inhibitors. |
2008 Jan-Apr |
Int. Rev. Immunol. |
pmid:18300054
|
Stradner MH et al. |
Spingosine-1-phosphate stimulates proliferation and counteracts interleukin-1 induced nitric oxide formation in articular chondrocytes. |
2008 |
Osteoarthr. Cartil. |
pmid:17703957
|
Wacker BK et al. |
Endothelial cell migration on RGD-peptide-containing PEG hydrogels in the presence of sphingosine 1-phosphate. |
2008 |
Biophys. J. |
pmid:17827231
|
Provençal M et al. |
Tissue factor pathway inhibitor (TFPI) interferes with endothelial cell migration by inhibition of both the Erk pathway and focal adhesion proteins. |
2008 |
Thromb. Haemost. |
pmid:18327407
|
Beyer T and Meyer-Hermann M |
Mechanisms of organogenesis of primary lymphoid follicles. |
2008 |
Int. Immunol. |
pmid:18334502
|
Sensken SC et al. |
Selective activation of G alpha i mediated signalling of S1P3 by FTY720-phosphate. |
2008 |
Cell. Signal. |
pmid:18313900
|
Kunisawa J et al. |
Sphingosine 1-phosphate-dependent trafficking of peritoneal B cells requires functional NFkappaB-inducing kinase in stromal cells. |
2008 |
Blood |
pmid:18292290
|
Nicol GD |
Nerve growth factor, sphingomyelins, and sensitization in sensory neurons. |
2008 |
Sheng Li Xue Bao |
pmid:18958367
|
Park HY et al. |
K6PC-5, a novel sphingosine kinase activator, improves long-term ultraviolet light-exposed aged murine skin. |
2008 |
Exp. Dermatol. |
pmid:18341573
|
Meacci E et al. |
Sphingosine kinase activity is required for myogenic differentiation of C2C12 myoblasts. |
2008 |
J. Cell. Physiol. |
pmid:17654519
|
Igarashi J and Michel T |
The enigma of sphingosine 1-phosphate synthesis: a novel role for endothelial sphingosine kinases. |
2008 |
Circ. Res. |
pmid:18369161
|
Gohda M et al. |
Sphingosine 1-phosphate regulates the egress of IgA plasmablasts from Peyer's patches for intestinal IgA responses. |
2008 |
J. Immunol. |
pmid:18390715
|
Avery K et al. |
Sphingosine-1-phosphate mediates transcriptional regulation of key targets associated with survival, proliferation, and pluripotency in human embryonic stem cells. |
2008 |
Stem Cells Dev. |
pmid:18393631
|
Eskan MA et al. |
TLR4 and S1P receptors cooperate to enhance inflammatory cytokine production in human gingival epithelial cells. |
2008 |
Eur. J. Immunol. |
pmid:18395849
|
Krump-Konvalinkova V et al. |
FTY720 inhibits S1P-mediated endothelial healing: relationship to S1P1-receptor surface expression. |
2008 |
Biochem. Biophys. Res. Commun. |
pmid:18402775
|
Olivera A |
Unraveling the complexities of sphingosine-1-phosphate function: the mast cell model. |
2008 |
Prostaglandins Other Lipid Mediat. |
pmid:18403224
|
Sefcik LS et al. |
Sustained release of sphingosine 1-phosphate for therapeutic arteriogenesis and bone tissue engineering. |
2008 |
Biomaterials |
pmid:18405965
|
Arce FT et al. |
Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: role of cortactin. |
2008 |
Biophys. J. |
pmid:18408039
|
Goetzl EJ et al. |
Regulation of the roles of sphingosine 1-phosphate and its type 1 G protein-coupled receptor in T cell immunity and autoimmunity. |
2008 |
Biochim. Biophys. Acta |
pmid:18381082
|
Hong JH et al. |
K6PC-5, a direct activator of sphingosine kinase 1, promotes epidermal differentiation through intracellular Ca2+ signaling. |
2008 |
J. Invest. Dermatol. |
pmid:18385762
|
Lebman DA and Spiegel S |
Cross-talk at the crossroads of sphingosine-1-phosphate, growth factors, and cytokine signaling. |
2008 |
J. Lipid Res. |
pmid:18387885
|
Nishiuma T et al. |
Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model. |
2008 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:18359884
|
Chung FY et al. |
Signaling mechanisms of sphingosine 1-phosphate-induced ERK1/2 activation in cultured feline esophageal smooth muscle cells. |
2008 |
Arch. Pharm. Res. |
pmid:19023540
|
Osborne N et al. |
The spinster homolog, two of hearts, is required for sphingosine 1-phosphate signaling in zebrafish. |
2008 |
Curr. Biol. |
pmid:19062281
|
Szczepaniak WS et al. |
Sphingosine 1-phosphate rescues canine LPS-induced acute lung injury and alters systemic inflammatory cytokine production in vivo. |
2008 |
Transl Res |
pmid:19010292
|
Serebrov VY et al. |
Functional activity of sphingomyelin cycle in rat liver in chronic toxic hepatitis. |
2008 |
Bull. Exp. Biol. Med. |
pmid:19513367
|
Zanin M et al. |
Trophic action of sphingosine 1-phosphate in denervated rat soleus muscle. |
2008 |
Am. J. Physiol., Cell Physiol. |
pmid:17942639
|
Tölle M et al. |
HDL-associated lysosphingolipids inhibit NAD(P)H oxidase-dependent monocyte chemoattractant protein-1 production. |
2008 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:18483405
|
Huang YT et al. |
Sphingosine 1-phosphate induces platelet/endothelial cell adhesion molecule-1 phosphorylation in human endothelial cells through cSrc and Fyn. |
2008 |
Cell. Signal. |
pmid:18502612
|
Chen LY et al. |
Cytosolic phospholipase A2alpha activation induced by S1P is mediated by the S1P3 receptor in lung epithelial cells. |
2008 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:18502815
|
Wamhoff BR et al. |
Sphingosine-1-phosphate receptor subtypes differentially regulate smooth muscle cell phenotype. |
2008 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:18535287
|
Rapizzi E et al. |
Sphingosine 1-phosphate differentially regulates proliferation of C2C12 reserve cells and myoblasts. |
2008 |
Mol. Cell. Biochem. |
pmid:18454302
|
Son DJ et al. |
Enhanced release of sphingosine-1-phosphate from hypercholesterolemic platelets: role in development of hypercholesterolemic atherosclerosis. |
2008 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:18571912
|
Peavy RD and Metcalfe DD |
Understanding the mechanisms of anaphylaxis. |
2008 |
Curr Opin Allergy Clin Immunol |
pmid:18596587
|
Cheon S et al. |
Sphingosine kinase inhibitor suppresses IL-18-induced interferon-gamma production through inhibition of p38 MAPK activation in human NK cells. |
2008 |
Biochem. Biophys. Res. Commun. |
pmid:18602364
|
Ohkawa R et al. |
Plasma sphingosine-1-phosphate measurement in healthy subjects: close correlation with red blood cell parameters. |
2008 |
Ann. Clin. Biochem. |
pmid:18583619
|
Takuwa Y et al. |
Sphingosine-1-phosphate signaling and biological activities in the cardiovascular system. |
2008 |
Biochim. Biophys. Acta |
pmid:18472021
|
Takabe K et al. |
"Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets. |
2008 |
Pharmacol. Rev. |
pmid:18552276
|
Jessup W |
Lipid metabolism: sources and stability of plasma sphingosine-1-phosphate. |
2008 |
Curr. Opin. Lipidol. |
pmid:18769238
|
Rivera J et al. |
New insights on mast cell activation via the high affinity receptor for IgE. |
2008 |
Adv. Immunol. |
pmid:18772004
|
Westerberg LS et al. |
WASP confers selective advantage for specific hematopoietic cell populations and serves a unique role in marginal zone B-cell homeostasis and function. |
2008 |
Blood |
pmid:18772454
|
Huang WR et al. |
[SphK-1/S1P signal pathway in CML cells]. |
2008 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:18718048
|
Serrano-Sanchez M et al. |
Signaling pathways involved in sphingosine kinase activation and sphingosine-1-phosphate release in rat myometrium in late pregnancy: role in the induction of cyclooxygenase 2. |
2008 |
Endocrinology |
pmid:18723875
|
Ohama T et al. |
Sphingosine-1-phosphate enhances IL-1{beta}-induced COX-2 expression in mouse intestinal subepithelial myofibroblasts. |
2008 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:18703638
|
Kihara A and Igarashi Y |
Production and release of sphingosine 1-phosphate and the phosphorylated form of the immunomodulator FTY720. |
2008 |
Biochim. Biophys. Acta |
pmid:18555808
|
Kaya H et al. |
Does sphingosine-1-phosphate have a protective effect on cyclophosphamide- and irradiation-induced ovarian damage in the rat model? |
2008 |
Fertil. Steril. |
pmid:17517398
|
Worrall D et al. |
Involvement of sphingosine kinase in plant cell signalling. |
2008 |
Plant J. |
pmid:18557834
|
Heller R et al. |
Overlapping and distinct roles for PI3Kbeta and gamma isoforms in S1P-induced migration of human and mouse endothelial cells. |
2008 |
Cardiovasc. Res. |
pmid:18558630
|
Levkau B |
Sphingosine-1-phosphate in the regulation of vascular tone: a finely tuned integration system of S1P sources, receptors, and vascular responsiveness. |
2008 |
Circ. Res. |
pmid:18669929
|
Ohuchi H et al. |
Expression patterns of the lysophospholipid receptor genes during mouse early development. |
2008 |
Dev. Dyn. |
pmid:18924241
|
Ledgerwood LG et al. |
The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics. |
2008 |
Nat. Immunol. |
pmid:18037890
|
Nussbaumer P et al. |
An efficient, one-pot synthesis of various ceramide 1-phosphates from sphingosine 1-phosphate. |
2008 |
Chem. Phys. Lipids |
pmid:18039471
|
Srinivasan S et al. |
Sphingosine-1-phosphate reduces CD4+ T-cell activation in type 1 diabetes through regulation of hypoxia-inducible factor short isoform I.1 and CD69. |
2008 |
Diabetes |
pmid:18003758
|
Johann AM et al. |
Apoptotic cell-derived sphingosine-1-phosphate promotes HuR-dependent cyclooxygenase-2 mRNA stabilization and protein expression. |
2008 |
J. Immunol. |
pmid:18178864
|
Oskeritzian CA et al. |
Distinct roles of sphingosine kinases 1 and 2 in human mast-cell functions. |
2008 |
Blood |
pmid:18178871
|
Oyama O et al. |
The lysophospholipid mediator sphingosine-1-phosphate promotes angiogenesis in vivo in ischaemic hindlimbs of mice. |
2008 |
Cardiovasc. Res. |
pmid:18187460
|
Patschan S et al. |
Lipid mediators of autophagy in stress-induced premature senescence of endothelial cells. |
2008 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:18203850
|
Eskan MA et al. |
Sphingosine 1-phosphate 1 and TLR4 mediate IFN-beta expression in human gingival epithelial cells. |
2008 |
J. Immunol. |
pmid:18209079
|
Sekiguchi M et al. |
Role of sphingosine 1-phosphate in the pathogenesis of Sjögren's syndrome. |
2008 |
J. Immunol. |
pmid:18209090
|
Brunati AM et al. |
Cross-talk between PDGF and S1P signalling elucidates the inhibitory effect and potential antifibrotic action of the immunomodulator FTY720 in activated HSC-cultures. |
2008 |
Biochim. Biophys. Acta |
pmid:18157950
|
Gingras D et al. |
Sphingosine-1-phosphate induces the association of membrane-type 1 matrix metalloproteinase with p130Cas in endothelial cells. |
2008 |
FEBS Lett. |
pmid:18164686
|