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Sphingosine-1-phosphate improves endothelialization with reduction of thrombosis in recellularized human umbilical vein graft by inhibiting syndecan-1 shedding in vitro. |
2017 |
Acta Biomater |
pmid:28110073
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Lee MH et al. |
S1P in HDL promotes interaction between SR-BI and S1PR1 and activates S1PR1-mediated biological functions: calcium flux and S1PR1 internalization. |
2017 |
J. Lipid Res. |
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Ruiz M et al. |
High-Density Lipoprotein-Associated Apolipoprotein M Limits Endothelial Inflammation by Delivering Sphingosine-1-Phosphate to the Sphingosine-1-Phosphate Receptor 1. |
2017 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:27879252
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Barnawi J et al. |
Reduced DNA methylation of sphingosine-1 phosphate receptor 5 in alveolar macrophages in COPD: A potential link to failed efferocytosis. |
2017 |
Respirology |
pmid:27868302
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Frias MA et al. |
High-density lipoprotein-associated sphingosine-1-phosphate activity in heterozygous familial hypercholesterolaemia. |
2017 |
Eur. J. Clin. Invest. |
pmid:27861771
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Fang V et al. |
Gradients of the signaling lipid S1P in lymph nodes position natural killer cells and regulate their interferon-γ response. |
2017 |
Nat. Immunol. |
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Wang R et al. |
Hepatic Stellate Cell Selective Disruption of Dynamin-2 GTPase Increases Murine Fibrogenesis through Up-Regulation of Sphingosine-1 Phosphate-Induced Cell Migration. |
2017 |
Am. J. Pathol. |
pmid:27840081
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O'Sullivan S and Dev KK |
Sphingosine-1-phosphate receptor therapies: Advances in clinical trials for CNS-related diseases. |
2017 |
Neuropharmacology |
pmid:27825807
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Engel N et al. |
Synergistic Action of Genistein and Calcitriol in Immature Osteosarcoma MG-63 Cells by SGPL1 Up-Regulation. |
2017 |
PLoS ONE |
pmid:28125641
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Yanagida K and Hla T |
Vascular and Immunobiology of the Circulatory Sphingosine 1-Phosphate Gradient. |
2017 |
Annu. Rev. Physiol. |
pmid:27813829
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Vogt D and Stark H |
Therapeutic Strategies and Pharmacological Tools Influencing S1P Signaling and Metabolism. |
2017 |
Med Res Rev |
pmid:27480072
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Polzin A et al. |
Plasma sphingosine-1-phosphate concentrations are associated with systolic heart failure in patients with ischemic heart disease. |
2017 |
J. Mol. Cell. Cardiol. |
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Innamorati G et al. |
Pleiotropic effects of sphingosine-1-phosphate signaling to control human chorionic mesenchymal stem cell physiology. |
2017 |
Cell Death Dis |
pmid:28703804
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Bougault C et al. |
Involvement of sphingosine kinase/sphingosine 1-phosphate metabolic pathway in spondyloarthritis. |
2017 |
Bone |
pmid:28684192
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Tsai CH et al. |
Sphingosine-1-phosphate suppresses chondrosarcoma metastasis by upregulation of tissue inhibitor of metalloproteinase 3 through suppressing miR-101 expression. |
2017 |
Mol Oncol |
pmid:28672103
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Schmidt KG et al. |
Sphingosine-1-Phosphate Receptor 5 Modulates Early-Stage Processes during Fibrogenesis in a Mouse Model of Systemic Sclerosis: A Pilot Study. |
2017 |
Front Immunol |
pmid:29033951
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Xie Z et al. |
Targeting sphingosine-1-phosphate signaling for cancer therapy. |
2017 |
Sci China Life Sci |
pmid:28623546
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Yanagida K et al. |
Size-selective opening of the blood-brain barrier by targeting endothelial sphingosine 1-phosphate receptor 1. |
2017 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:28396408
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Takahashi C et al. |
Vehicle-dependent Effects of Sphingosine 1-phosphate on Plasminogen Activator Inhibitor-1 Expression. |
2017 |
J. Atheroscler. Thromb. |
pmid:28321011
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Pierucci F et al. |
Vitamin D protects against Aβ peptide cytotoxicity in differentiated human neuroblastoma SH- SY5Y cells: A role for S1P1/p38MAPK/ATF4 axis. |
2017 |
Neuropharmacology |
pmid:28077289
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Leo A et al. |
The Sphingosine 1-Phosphate Signaling Pathway in Epilepsy: A Possible Role for the Immunomodulator Drug Fingolimod in Epilepsy Treatment. |
2017 |
CNS Neurol Disord Drug Targets |
pmid:27823573
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Vu TM et al. |
Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets. |
2017 |
Nature |
pmid:29045386
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Reinhard NR et al. |
The balance between Gα-Cdc42/Rac and Gα/-RhoA pathways determines endothelial barrier regulation by sphingosine-1-phosphate. |
2017 |
Mol. Biol. Cell |
pmid:28954861
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Natarajan V et al. |
Expression profiling of genes regulated by sphingosine kinase1 signaling in a murine model of hyperoxia induced neonatal bronchopulmonary dysplasia. |
2017 |
BMC Genomics |
pmid:28851267
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Hajny S and Christoffersen C |
A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation. |
2017 |
Int J Mol Sci |
pmid:28749426
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Bertlich M et al. |
Fingolimod (FTY-720) is Capable of Reversing Tumor Necrosis Factor Induced Decreases in Cochlear Blood Flow. |
2017 |
Otol. Neurotol. |
pmid:28742634
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Kurano M et al. |
Involvement of Band3 in the efflux of sphingosine 1-phosphate from erythrocytes. |
2017 |
PLoS ONE |
pmid:28494002
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Al-Jarallah A and Oriowo M |
The effect of sphingosine-1-phosphate on colonic smooth muscle contractility: Modulation by TNBS-induced colitis. |
2017 |
PLoS ONE |
pmid:28493876
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Chen T et al. |
Sphingosine-1 phosphate promotes intestinal epithelial cell proliferation via S1PR2. |
2017 |
Front Biosci (Landmark Ed) |
pmid:27814635
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Beider K et al. |
The Sphingosine-1-Phosphate Modulator FTY720 Targets Multiple Myeloma via the CXCR4/CXCL12 Pathway. |
2017 |
Clin. Cancer Res. |
pmid:27697999
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Thieme M et al. |
Sphingosine-1-phosphate modulators in inflammatory skin diseases - lining up for clinical translation. |
2017 |
Exp. Dermatol. |
pmid:27574180
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Chang N et al. |
HuR mediates motility of human bone marrow-derived mesenchymal stem cells triggered by sphingosine 1-phosphate in liver fibrosis. |
2017 |
J. Mol. Med. |
pmid:27543493
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Gudipaty SA and Rosenblatt J |
Epithelial cell extrusion: Pathways and pathologies. |
2017 |
Semin. Cell Dev. Biol. |
pmid:27212253
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Mendoza A et al. |
Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells. |
2017 |
Nature |
pmid:28538737
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Ma S et al. |
A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis. |
2017 |
Dev. Cell |
pmid:28535372
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Meshcheryakova A et al. |
Sphingosine 1-phosphate signaling in bone remodeling: multifaceted roles and therapeutic potential. |
2017 |
Expert Opin. Ther. Targets |
pmid:28524744
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Ko J et al. |
Sphingosine-1-Phosphate Mediates Fibrosis in Orbital Fibroblasts in Graves' Orbitopathy. |
2017 |
Invest. Ophthalmol. Vis. Sci. |
pmid:28492873
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Aoyama-Araki Y et al. |
Sphingosine-1-Phosphate (S1P)-Related Response of Human Conjunctival Fibroblasts After Filtration Surgery for Glaucoma. |
2017 |
Invest. Ophthalmol. Vis. Sci. |
pmid:28418499
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Frej C et al. |
A Shift in ApoM/S1P Between HDL-Particles in Women With Type 1 Diabetes Mellitus Is Associated With Impaired Anti-Inflammatory Effects of the ApoM/S1P Complex. |
2017 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:28385702
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Nakajima M et al. |
The role of sphingosine-1-phosphate in the tumor microenvironment and its clinical implications. |
2017 |
Tumour Biol. |
pmid:28381169
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Garbowska M et al. |
Sphingolipids metabolism in the salivary glands of rats with obesity and streptozotocin induced diabetes. |
2017 |
J. Cell. Physiol. |
pmid:28369933
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Tafelmeier M et al. |
Mildly oxidized HDL decrease agonist-induced platelet aggregation and release of pro-coagulant platelet extracellular vesicles. |
2017 |
J. Steroid Biochem. Mol. Biol. |
pmid:27163393
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Ruiz M et al. |
HDL-associated ApoM is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 & S1P3 receptors on vascular endothelium. |
2017 |
Lipids Health Dis |
pmid:28179022
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Moruno-Manchon JF et al. |
Inhibiting sphingosine kinase 2 mitigates mutant Huntingtin-induced neurodegeneration in neuron models of Huntington disease. |
2017 |
Hum. Mol. Genet. |
pmid:28175299
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Rojas-Canales D et al. |
Local Sphingosine Kinase 1 Activity Improves Islet Transplantation. |
2017 |
Diabetes |
pmid:28174291
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Dela Paz NG et al. |
Shear stress induces Gα activation independently of G protein-coupled receptor activation in endothelial cells. |
2017 |
Am. J. Physiol., Cell Physiol. |
pmid:28148497
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Green CL et al. |
The effects of graded levels of calorie restriction: IX. Global metabolomic screen reveals modulation of carnitines, sphingolipids and bile acids in the liver of C57BL/6 mice. |
2017 |
Aging Cell |
pmid:28139067
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Vishwakarma S et al. |
Altered Expression of Sphingosine-1-Phosphate Metabolizing Enzymes in Oral Cancer Correlate With Clinicopathological Attributes. |
2017 |
Cancer Invest. |
pmid:28135860
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Kurano M et al. |
Involvement of CETP (Cholesteryl Ester Transfer Protein) in the Shift of Sphingosine-1-Phosphate Among Lipoproteins and in the Modulation of its Functions. |
2017 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:28126827
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Wang Y et al. |
The role of sphingosine 1-phosphate receptor 2 in bile-acid-induced cholangiocyte proliferation and cholestasis-induced liver injury in mice. |
2017 |
Hepatology |
pmid:28120434
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