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PLoS ONE |
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Downregulation of sphingosine 1-phosphate (S1P) receptor 1 by dexamethasone inhibits S1P-induced mesangial cell migration. |
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Biol. Chem. |
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Tumor necrosis factor (TNF) receptor-associated factor (TRAF)-interacting protein (TRIP) negatively regulates the TRAF2 ubiquitin-dependent pathway by suppressing the TRAF2-sphingosine 1-phosphate (S1P) interaction. |
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Pelvic organ prolapse is associated with alteration of sphingosine-1-phosphate/Rho-kinase signalling pathway in human vaginal wall. |
2015 |
J Obstet Gynaecol |
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Sphingolipids in the DNA damage response. |
2015 |
Adv Biol Regul |
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The role of serum amyloid A and sphingosine-1-phosphate on high-density lipoprotein functionality. |
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Taurocholate Induces Cyclooxygenase-2 Expression via the Sphingosine 1-phosphate Receptor 2 in a Human Cholangiocarcinoma Cell Line. |
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Sphingosine 1-phosphate enhances the excitability of rat sensory neurons through activation of sphingosine 1-phosphate receptors 1 and/or 3. |
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J Neuroinflammation |
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Smad3 deficiency leads to mandibular condyle degradation via the sphingosine 1-phosphate (S1P)/S1P3 signaling axis. |
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Pulmonary endothelial cell barrier enhancement by novel FTY720 analogs: methoxy-FTY720, fluoro-FTY720, and β-glucuronide-FTY720. |
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Chem. Phys. Lipids |
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Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. |
2015 |
Sci Signal |
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Sphingosine-1-Phosphate Is a Novel Regulator of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity. |
2015 |
PLoS ONE |
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Role of N-WASP in Endothelial Monolayer Formation and Integrity. |
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Bioactive lysophospholipids: role in regulation of aqueous humor outflow and intraocular pressure in the context of pathobiology and therapy of glaucoma. |
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J Ocul Pharmacol Ther |
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Corticosteroids inhibit sphingosine 1-phosphate-induced interleukin-6 secretion from human airway smooth muscle via mitogen-activated protein kinase phosphatase 1-mediated repression of mitogen and stress-activated protein kinase 1. |
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Sphingosine 1-phosphate (S1P) induces COX-2 expression and PGE2 formation via S1P receptor 2 in renal mesangial cells. |
2014 |
Biochim. Biophys. Acta |
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The role of sphingosine 1-phosphate in inflammation and cancer. |
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Adv Biol Regul |
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ASN Neuro |
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Increased levels of sphingosine-1-phosphate in cerebrospinal fluid of patients diagnosed with tick-borne encephalitis. |
2014 |
J Neuroinflammation |
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J. Pharmacol. Exp. Ther. |
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Sphingosine 1-phosphate: a potential molecular target for ovarian cancer therapy? |
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Cancer Invest. |
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Integrin α9 on lymphatic endothelial cells regulates lymphocyte egress. |
2014 |
Proc. Natl. Acad. Sci. U.S.A. |
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Targeted anti-apoptosis activity for ovarian protection against chemotherapy-induced ovarian gonadotoxicity. |
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Reprod. Biomed. Online |
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Biochem. Soc. Trans. |
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Inflammatory lipid sphingosine-1-phosphate upregulates C-reactive protein via C/EBPβ and potentiates breast cancer progression. |
2014 |
Oncogene |
pmid:23955082
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S1P-Dependent trafficking of intracellular yersinia pestis through lymph nodes establishes Buboes and systemic infection. |
2014 |
Immunity |
pmid:25238098
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Plague's partners in crime. |
2014 |
Immunity |
pmid:25238090
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Autocrine/paracrine sphingosine-1-phosphate fuels proliferative and stemness qualities of glioblastoma stem cells. |
2014 |
Glia |
pmid:25042636
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Sphingosine-1-phosphate induces pro-remodelling response in airway smooth muscle cells. |
2014 |
Allergy |
pmid:25041788
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Controlled release of sphingosine-1-phosphate agonist with gelatin hydrogels for macrophage recruitment. |
2014 |
Acta Biomater |
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Sphingosine 1-phosphate induced anti-atherogenic and atheroprotective M2 macrophage polarization through IL-4. |
2014 |
Cell. Signal. |
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Role of sphingosine kinase 1 and sphingosine-1-phosphate in CD40 signaling and IgE class switching. |
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FASEB J. |
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Antiapoptotic agent sphingosine-1-phosphate protects vitrified murine ovarian grafts. |
2014 |
Reprod Sci |
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Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis-derived prostate cancer cells. |
2014 |
Mol Oncol |
pmid:24768038
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Sphingosine kinase 1 expressed by endothelial colony-forming cells has a critical role in their revascularization activity. |
2014 |
Cardiovasc. Res. |
pmid:24743591
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Sphingosine 1-phosphate (S1P) induced interleukin-8 (IL-8) release is mediated by S1P receptor 2 and nuclear factor κB in BEAS-2B cells. |
2014 |
PLoS ONE |
pmid:24743449
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Jesko H et al. |
Sphingosine kinases modulate the secretion of amyloid β precursor protein from SH-SY5Y neuroblastoma cells: the role of α-synuclein. |
2014 |
Folia Neuropathol |
pmid:24729344
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Roles of sphingosine-1-phosphate in reproduction. |
2014 |
Reprod Sci |
pmid:24336672
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Sphingosine 1-phosphate (S1P) promotes mitochondrial biogenesis in Hep G2 cells by activating Peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α). |
2014 |
Cell Stress Chaperones |
pmid:24293320
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Chen JJ et al. |
Non-genomic rapid responses via progesterone in human peripheral T cells are not indirectly mimicked by sphingosine 1-phosphate. |
2014 |
Steroids |
pmid:24269742
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The identification of GPR3 inverse agonist AF64394; the first small molecule inhibitor of GPR3 receptor function. |
2014 |
Bioorg. Med. Chem. Lett. |
pmid:25442311
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Identification of a novel small-molecule agonist for human G protein-coupled receptor 3. |
2014 |
J. Pharmacol. Exp. Ther. |
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