Radi ZA and Vogel MW |
Gastric parietal cell atrophy and depletion after administration of a sphingosine-1-phosphate 1 inhibitor. |
2014 |
Toxicol Pathol |
pmid:24178572
|
Che W et al. |
Corticosteroids inhibit sphingosine 1-phosphate-induced interleukin-6 secretion from human airway smooth muscle via mitogen-activated protein kinase phosphatase 1-mediated repression of mitogen and stress-activated protein kinase 1. |
2014 |
Am. J. Respir. Cell Mol. Biol. |
pmid:24032470
|
Chang N et al. |
Sphingosine 1-phosphate receptors negatively regulate collagen type I/III expression in human bone marrow-derived mesenchymal stem cell. |
2014 |
J. Cell. Biochem. |
pmid:24038457
|
Völzke A et al. |
Sphingosine 1-phosphate (S1P) induces COX-2 expression and PGE2 formation via S1P receptor 2 in renal mesangial cells. |
2014 |
Biochim. Biophys. Acta |
pmid:24064301
|
Kurano M et al. |
Induction of insulin secretion by apolipoprotein M, a carrier for sphingosine 1-phosphate. |
2014 |
Biochim. Biophys. Acta |
pmid:24814049
|
Arya D et al. |
Sphingosine-1-phosphate promotes the differentiation of adipose-derived stem cells into endothelial nitric oxide synthase (eNOS) expressing endothelial-like cells. |
2014 |
J. Biomed. Sci. |
pmid:24898615
|
Maceyka M and Spiegel S |
Sphingolipid metabolites in inflammatory disease. |
2014 |
Nature |
pmid:24899305
|
Nagata Y et al. |
Sphingosine-1-phosphate mediates epidermal growth factor-induced muscle satellite cell activation. |
2014 |
Exp. Cell Res. |
pmid:24960577
|
Ceccom J et al. |
[Sphingosine 1-phosphate as a biomarker for Alzheimer's disease?]. |
2014 |
Med Sci (Paris) |
pmid:24939530
|
Moxon JV et al. |
Comparison of the serum lipidome in patients with abdominal aortic aneurysm and peripheral artery disease. |
2014 |
Circ Cardiovasc Genet |
pmid:24448739
|
Gorlino CV et al. |
Neutrophils exhibit differential requirements for homing molecules in their lymphatic and blood trafficking into draining lymph nodes. |
2014 |
J. Immunol. |
pmid:25015824
|
Uhlig S et al. |
Differential regulation of lung endothelial permeability in vitro and in situ. |
2014 |
Cell. Physiol. Biochem. |
pmid:24977477
|
Nagamatsu T et al. |
Emerging roles for lysophospholipid mediators in pregnancy. |
2014 |
Am. J. Reprod. Immunol. |
pmid:24689547
|
Shimizu Y et al. |
Potentials of the circulating pruritogenic mediator lysophosphatidic acid in development of allergic skin inflammation in mice: role of blood cell-associated lysophospholipase D activity of autotaxin. |
2014 |
Am. J. Pathol. |
pmid:24641902
|
de Assuncao TM et al. |
New role for Kruppel-like factor 14 as a transcriptional activator involved in the generation of signaling lipids. |
2014 |
J. Biol. Chem. |
pmid:24759103
|
Tibboel J et al. |
Sphingolipids in lung growth and repair. |
2014 |
Chest |
pmid:24394822
|
Huang K et al. |
AP-1 regulates sphingosine kinase 1 expression in a positive feedback manner in glomerular mesangial cells exposed to high glucose. |
2014 |
Cell. Signal. |
pmid:24342046
|
Slattum G et al. |
Autophagy in oncogenic K-Ras promotes basal extrusion of epithelial cells by degrading S1P. |
2014 |
Curr. Biol. |
pmid:24361067
|
Miller DS |
Sphingolipid signaling reduces basal P-glycoprotein activity in renal proximal tubule. |
2014 |
J. Pharmacol. Exp. Ther. |
pmid:24385389
|
Dai L et al. |
Sphingosine 1-phosphate: a potential molecular target for ovarian cancer therapy? |
2014 |
Cancer Invest. |
pmid:24499107
|
Ito K et al. |
Integrin α9 on lymphatic endothelial cells regulates lymphocyte egress. |
2014 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:24516133
|
Nakajima C et al. |
The lipoprotein receptor LRP1 modulates sphingosine-1-phosphate signaling and is essential for vascular development. |
2014 |
Development |
pmid:25377550
|
Takeshita E et al. |
Diacylglycerol kinase γ is a novel anionic phospholipid binding protein with a selective binding preference. |
2014 |
Biochem. Biophys. Res. Commun. |
pmid:24486543
|
Barnes J and Dweik RA |
Is pulmonary hypertension a metabolic disease? |
2014 |
Am. J. Respir. Crit. Care Med. |
pmid:25360726
|
Chen J et al. |
Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss. |
2014 |
PLoS Genet. |
pmid:25356849
|
Degagné E et al. |
Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs. |
2014 |
J. Clin. Invest. |
pmid:25347472
|
Wang F and Ye P |
Improving heart function by modulating myocardiocyte autophagy: a possible novel mechanism for cardiovascular protection of high-density lipoprotein. |
2014 |
Lipids Health Dis |
pmid:25339382
|
Keller J et al. |
Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts. |
2014 |
Nat Commun |
pmid:25333900
|
Lepletier A et al. |
Early double-negative thymocyte export in Trypanosoma cruzi infection is restricted by sphingosine receptors and associated with human chagas disease. |
2014 |
PLoS Negl Trop Dis |
pmid:25330249
|
Bradley E et al. |
Critical role of Spns2, a sphingosine-1-phosphate transporter, in lung cancer cell survival and migration. |
2014 |
PLoS ONE |
pmid:25330231
|
Sutter I et al. |
Apolipoprotein M modulates erythrocyte efflux and tubular reabsorption of sphingosine-1-phosphate. |
2014 |
J. Lipid Res. |
pmid:24950692
|
Cahalan SM |
Chemical and genetic tools to explore S1P biology. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728593
|
Arnon TI and Cyster JG |
Blood, sphingosine-1-phosphate and lymphocyte migration dynamics in the spleen. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728595
|
Oldstone MB and Rosen H |
Cytokine storm plays a direct role in the morbidity and mortality from influenza virus infection and is chemically treatable with a single sphingosine-1-phosphate agonist molecule. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728596
|
Martin R and Sospedra M |
Sphingosine-1 phosphate and central nervous system. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728597
|
Kong Y et al. |
Sphingosine-1-phosphate/S1P receptors signaling modulates cell migration in human bone marrow-derived mesenchymal stem cells. |
2014 |
Mediators Inflamm. |
pmid:25147438
|
Shayegi N et al. |
CXCR4 blockade and sphingosine-1-phosphate activation facilitate engraftment of haematopoietic stem and progenitor cells in a non-myeloablative transplant model. |
2014 |
Br. J. Haematol. |
pmid:24180707
|
Nagahashi M et al. |
Sphingosine-1-phosphate transporters as targets for cancer therapy. |
2014 |
Biomed Res Int |
pmid:25133174
|
Nguyen AV et al. |
STAT3 and sphingosine-1-phosphate in inflammation-associated colorectal cancer. |
2014 |
World J. Gastroenterol. |
pmid:25132744
|
Kim ES et al. |
Inflammatory lipid sphingosine-1-phosphate upregulates C-reactive protein via C/EBPβ and potentiates breast cancer progression. |
2014 |
Oncogene |
pmid:23955082
|
Deng Y et al. |
Sphingosine Kinase-1/sphingosine 1-phosphate pathway in diabetic nephropathy. |
2014 |
Chin. Med. J. |
pmid:25131242
|
Ogle ME et al. |
Engineering in vivo gradients of sphingosine-1-phosphate receptor ligands for localized microvascular remodeling and inflammatory cell positioning. |
2014 |
Acta Biomater |
pmid:25128750
|
St John AL et al. |
S1P-Dependent trafficking of intracellular yersinia pestis through lymph nodes establishes Buboes and systemic infection. |
2014 |
Immunity |
pmid:25238098
|
Bi Y et al. |
Sphingosine-1-phosphate mediates a reciprocal signaling pathway between stellate cells and cancer cells that promotes pancreatic cancer growth. |
2014 |
Am. J. Pathol. |
pmid:25111230
|
Ishitsuka A et al. |
FTY720 and cisplatin synergistically induce the death of cisplatin-resistant melanoma cells through the downregulation of the PI3K pathway and the decrease in epidermal growth factor receptor expression. |
2014 |
Int. J. Mol. Med. |
pmid:25109763
|
Rolin J and Maghazachi AA |
Implications of chemokines, chemokine receptors, and inflammatory lipids in atherosclerosis. |
2014 |
J. Leukoc. Biol. |
pmid:24493826
|
Schwalm S et al. |
Targeting the sphingosine kinase/sphingosine 1-phosphate pathway to treat chronic inflammatory kidney diseases. |
2014 |
Basic Clin. Pharmacol. Toxicol. |
pmid:23789924
|
Tsai YC et al. |
Antiapoptotic agent sphingosine-1-phosphate protects vitrified murine ovarian grafts. |
2014 |
Reprod Sci |
pmid:23793475
|
Sattler K et al. |
HDL-bound sphingosine 1-phosphate (S1P) predicts the severity of coronary artery atherosclerosis. |
2014 |
Cell. Physiol. Biochem. |
pmid:24977490
|
Thuy AV et al. |
Sphingosine 1-phosphate in blood: function, metabolism, and fate. |
2014 |
Cell. Physiol. Biochem. |
pmid:24977489
|
Hait NC et al. |
Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory. |
2014 |
Nat. Neurosci. |
pmid:24859201
|
van Echten-Deckert G et al. |
Sphingosine-1-phosphate: boon and bane for the brain. |
2014 |
Cell. Physiol. Biochem. |
pmid:24977488
|
Fayyaz S et al. |
Divergent role of sphingosine 1-phosphate on insulin resistance. |
2014 |
Cell. Physiol. Biochem. |
pmid:24977487
|
Rahman MM et al. |
Sphingosine 1-phosphate induces neutrophil chemoattractant IL-8: repression by steroids. |
2014 |
PLoS ONE |
pmid:24647471
|
Halmer R et al. |
Sphingolipids: important players in multiple sclerosis. |
2014 |
Cell. Physiol. Biochem. |
pmid:24977485
|
Park SM et al. |
Sphingosine-1-phosphate lyase is expressed by CD68+ cells on the parenchymal side of marginal reticular cells in human lymph nodes. |
2014 |
Eur. J. Immunol. |
pmid:24825162
|
Arlt O et al. |
Sphingosine-1-phosphate modulates dendritic cell function: focus on non-migratory effects in vitro and in vivo. |
2014 |
Cell. Physiol. Biochem. |
pmid:24977479
|
Simmons S and Ishii M |
Sphingosine-1-phosphate: a master regulator of lymphocyte egress and immunity. |
2014 |
Arch. Immunol. Ther. Exp. (Warsz.) |
pmid:24276789
|
Don AS et al. |
Re-configuration of sphingolipid metabolism by oncogenic transformation. |
2014 |
Biomolecules |
pmid:24970218
|
Snelder N et al. |
Translational pharmacokinetic modeling of fingolimod (FTY720) as a paradigm compound subject to sphingosine kinase-mediated phosphorylation. |
2014 |
Drug Metab. Dispos. |
pmid:24965813
|
Tarbell JM et al. |
Mechanosensing at the vascular interface. |
2014 |
Annu Rev Biomed Eng |
pmid:24905872
|
Shin KO et al. |
Ginsenoside compound K inhibits angiogenesis via regulation of sphingosine kinase-1 in human umbilical vein endothelial cells. |
2014 |
Arch. Pharm. Res. |
pmid:24687256
|
Yu H et al. |
Sphingosine kinase 1 improves cutaneous wound healing in diabetic rats. |
2014 |
Injury |
pmid:24685054
|
Smyth SS et al. |
Arguing the case for the autotaxin-lysophosphatidic acid-lipid phosphate phosphatase 3-signaling nexus in the development and complications of atherosclerosis. |
2014 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:24482375
|
Sykes DA et al. |
Investigating the molecular mechanisms through which FTY720-P causes persistent S1P1 receptor internalization. |
2014 |
Br. J. Pharmacol. |
pmid:24641481
|
Zhang J and Song J |
Amphiphilic degradable polymers for immobilization and sustained delivery of sphingosine 1-phosphate. |
2014 |
Acta Biomater |
pmid:24631657
|
Priceman SJ et al. |
S1PR1 is crucial for accumulation of regulatory T cells in tumors via STAT3. |
2014 |
Cell Rep |
pmid:24630990
|
Oizumi A et al. |
Pseudomonas-derived ceramidase induces production of inflammatory mediators from human keratinocytes via sphingosine-1-phosphate. |
2014 |
PLoS ONE |
pmid:24586752
|
Guan Z et al. |
Sphingosine-1-phosphate evokes unique segment-specific vasoconstriction of the renal microvasculature. |
2014 |
J. Am. Soc. Nephrol. |
pmid:24578134
|
Takabe K and Spiegel S |
Export of sphingosine-1-phosphate and cancer progression. |
2014 |
J. Lipid Res. |
pmid:24474820
|
Borge M et al. |
The expression of sphingosine-1 phosphate receptor-1 in chronic lymphocytic leukemia cells is impaired by tumor microenvironmental signals and enhanced by piceatannol and R406. |
2014 |
J. Immunol. |
pmid:25127862
|
Blaho VA and Hla T |
An update on the biology of sphingosine 1-phosphate receptors. |
2014 |
J. Lipid Res. |
pmid:24459205
|
Egom EE |
Sphingosine-1-phosphate signalling as a therapeutic target for patients with abnormal glucose metabolism and ischaemic heart disease. |
2014 |
J Cardiovasc Med (Hagerstown) |
pmid:23839592
|
Jensen T et al. |
The identification of GPR3 inverse agonist AF64394; the first small molecule inhibitor of GPR3 receptor function. |
2014 |
Bioorg. Med. Chem. Lett. |
pmid:25442311
|
Fincher J et al. |
G-protein-coupled receptor cell signaling pathways mediating embryonic chick retinal growth cone collapse induced by lysophosphatidic acid and sphingosine-1-phosphate. |
2014 |
Dev. Neurosci. |
pmid:25138637
|
Cencetti F et al. |
Lysophosphatidic acid stimulates cell migration of satellite cells. A role for the sphingosine kinase/sphingosine 1-phosphate axis. |
2014 |
FEBS J. |
pmid:25131845
|
Neuber C et al. |
Method to simultaneously determine the sphingosine 1-phosphate breakdown product (2E)-hexadecenal and its fatty acid derivatives using isotope-dilution HPLC-electrospray ionization-quadrupole/time-of-flight mass spectrometry. |
2014 |
Anal. Chem. |
pmid:25137547
|
Ratajczak MZ et al. |
The role of sphingosine-1 phosphate and ceramide-1 phosphate in trafficking of normal stem cells and cancer cells. |
2014 |
Expert Opin. Ther. Targets |
pmid:24188167
|
Chawla S et al. |
Exogenous sphingosine 1-phosphate protects murine splenocytes against hypoxia-induced injury. |
2014 |
Lipids |
pmid:24190514
|
Rao PV |
Bioactive lysophospholipids: role in regulation of aqueous humor outflow and intraocular pressure in the context of pathobiology and therapy of glaucoma. |
2014 Mar-Apr |
J Ocul Pharmacol Ther |
pmid:24283588
|
Urtz N et al. |
Sphingosine 1-Phosphate Produced by Sphingosine Kinase 2 Intrinsically Controls Platelet Aggregation In Vitro and In Vivo. |
2015 |
Circ. Res. |
pmid:26129975
|
Moolenaar WH |
Introduction to the ECR special issue on lysophospholipids in biology. |
2015 |
Exp. Cell Res. |
pmid:25746723
|
Carrera I et al. |
A comparative evaluation of a novel vaccine in APP/PS1 mouse models of Alzheimer's disease. |
2015 |
Biomed Res Int |
pmid:25759822
|
Ueda N |
Ceramide-induced apoptosis in renal tubular cells: a role of mitochondria and sphingosine-1-phoshate. |
2015 |
Int J Mol Sci |
pmid:25751724
|
Zhao S and Li J |
Sphingosine-1-phosphate induces the migration of thyroid follicular carcinoma cells through the microRNA-17/PTK6/ERK1/2 pathway. |
2015 |
PLoS ONE |
pmid:25748447
|
Konstantinou D et al. |
Growth factors mediated differentiation of mesenchymal stem cells to cardiac polymicrotissue using hanging drop and bioreactor. |
2015 |
Cell Biol. Int. |
pmid:25492631
|
Sano N et al. |
New drug delivery system for liver sinusoidal endothelial cells for ischemia-reperfusion injury. |
2015 |
World J. Gastroenterol. |
pmid:26668502
|
Matula K et al. |
Regulation of cellular sphingosine-1-phosphate by sphingosine kinase 1 and sphingosine-1-phopshate lyase determines chemotherapy resistance in gastroesophageal cancer. |
2015 |
BMC Cancer |
pmid:26493335
|
Barnawi J et al. |
Potential Link between the Sphingosine-1-Phosphate (S1P) System and Defective Alveolar Macrophage Phagocytic Function in Chronic Obstructive Pulmonary Disease (COPD). |
2015 |
PLoS ONE |
pmid:26485657
|
Moruno Manchon JF et al. |
Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy. |
2015 |
Sci Rep |
pmid:26477494
|
Deng Z et al. |
Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis. |
2015 |
Nat Commun |
pmid:25907800
|
Kihara Y et al. |
Lysophospholipid receptors in drug discovery. |
2015 |
Exp. Cell Res. |
pmid:25499971
|
Boczkowska-Radziwon B et al. |
Ozonation of human blood increases sphingosine-1-phosphate in plasma. |
2015 |
J. Physiol. Pharmacol. |
pmid:25903957
|
Simón MV et al. |
Sphingosine-1-Phosphate Is a Crucial Signal for Migration of Retina Müller Glial Cells. |
2015 |
Invest. Ophthalmol. Vis. Sci. |
pmid:26325420
|
Yang L et al. |
Sphingosine 1-Phosphate Receptor 2 and 3 Mediate Bone Marrow-Derived Monocyte/Macrophage Motility in Cholestatic Liver Injury in Mice. |
2015 |
Sci Rep |
pmid:26324256
|
Brünnert D et al. |
Sphingosine 1-phosphate regulates IL-8 expression and secretion via S1PR1 and S1PR2 receptors-mediated signaling in extravillous trophoblast derived HTR-8/SVneo cells. |
2015 |
Placenta |
pmid:26321412
|
Zhao YD et al. |
A Biochemical Approach to Understand the Pathogenesis of Advanced Pulmonary Arterial Hypertension: Metabolomic Profiles of Arginine, Sphingosine-1-Phosphate, and Heme of Human Lung. |
2015 |
PLoS ONE |
pmid:26317340
|
Nakagawa Y and Chiba K |
Diversity and plasticity of microglial cells in psychiatric and neurological disorders. |
2015 |
Pharmacol. Ther. |
pmid:26129625
|
Jeong SK et al. |
Sphingosine kinase 1 activation enhances epidermal innate immunity through sphingosine-1-phosphate stimulation of cathelicidin production. |
2015 |
J. Dermatol. Sci. |
pmid:26113114
|
Hyder CL et al. |
Sphingolipids inhibit vimentin-dependent cell migration. |
2015 |
J. Cell. Sci. |
pmid:25908861
|