Wang F and Fishman DA |
Lysophosphatidic acid and invasion. |
2009 |
Cancer Treat. Res. |
pmid:19763441
|
Kawamori T et al. |
Role for sphingosine kinase 1 in colon carcinogenesis. |
2009 |
FASEB J. |
pmid:18824518
|
Rohatagi S et al. |
Use of an exposure-response model to aid early drug development of an oral sphingosine 1-phosphate receptor modulator. |
2009 |
J Clin Pharmacol |
pmid:18948412
|
Satoh Y et al. |
Regulation by sphingolipids of the fate of FRTL-5 cells. |
2009 |
J. Biochem. |
pmid:18953023
|
Alford SK et al. |
Endothelial cell migration in human plasma is enhanced by a narrow range of added sphingosine 1-phosphate: implications for biomaterials design. |
2009 |
J Biomed Mater Res A |
pmid:18286622
|
Hendriks-Balk MC et al. |
Sphingosine-1-phosphate regulates RGS2 and RGS16 mRNA expression in vascular smooth muscle cells. |
2009 |
Eur. J. Pharmacol. |
pmid:19374869
|
Nincheri P et al. |
Sphingosine 1-phosphate induces differentiation of adipose tissue-derived mesenchymal stem cells towards smooth muscle cells. |
2009 |
Cell. Mol. Life Sci. |
pmid:19337690
|
Schulz C et al. |
Hematopoietic stem and progenitor cells: their mobilization and homing to bone marrow and peripheral tissue. |
2009 |
Immunol. Res. |
pmid:19340403
|
Sasaki H et al. |
pH dependence of sphingosine aggregation. |
2009 |
Biophys. J. |
pmid:19348755
|
Straub AC et al. |
Arsenic requires sphingosine-1-phosphate type 1 receptors to induce angiogenic genes and endothelial cell remodeling. |
2009 |
Am. J. Pathol. |
pmid:19349368
|
RodrÃguez C et al. |
Sphingosine-1-phosphate: A bioactive lipid that confers high-density lipoprotein with vasculoprotection mediated by nitric oxide and prostacyclin. |
2009 |
Thromb. Haemost. |
pmid:19350109
|
Formigli L et al. |
Regulation of transient receptor potential canonical channel 1 (TRPC1) by sphingosine 1-phosphate in C2C12 myoblasts and its relevance for a role of mechanotransduction in skeletal muscle differentiation. |
2009 |
J. Cell. Sci. |
pmid:19351713
|
Li Y and Yu KL |
[Advances in thrombin-protease-activated receptor 1-sphingosine 1-phosphate pathway during sepsis]. |
2009 |
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue |
pmid:19278594
|
He X et al. |
Quantitative analysis of sphingosine-1-phosphate by HPLC after napthalene-2,3-dicarboxaldehyde (NDA) derivatization. |
2009 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:19285924
|
Kenagy RD et al. |
Proliferative capacity of vein graft smooth muscle cells and fibroblasts in vitro correlates with graft stenosis. |
2009 |
J. Vasc. Surg. |
pmid:19307078
|
Milara J et al. |
Sphingosine-1-phosphate increases human alveolar epithelial IL-8 secretion, proliferation and neutrophil chemotaxis. |
2009 |
Eur. J. Pharmacol. |
pmid:19285497
|
Salinas NR et al. |
Lung tumor development in the presence of sphingosine 1-phosphate agonist FTY720. |
2009 |
Pathol. Oncol. Res. |
pmid:19214784
|
Choi SK et al. |
Comparison of contractile mechanisms of sphingosylphosphorylcholine and sphingosine-1-phosphate in rabbit coronary artery. |
2009 |
Cardiovasc. Res. |
pmid:19218288
|
Huang YL et al. |
Tyrosine sulphation of sphingosine 1-phosphate 1 (S1P1) is required for S1P-mediated cell migration in primary cultures of human umbilical vein endothelial cells. |
2009 |
J. Biochem. |
pmid:19692429
|
Antoon JW et al. |
Design, synthesis, and biological activity of a family of novel ceramide analogues in chemoresistant breast cancer cells. |
2009 |
J. Med. Chem. |
pmid:19694470
|
Zhao J et al. |
Phosphotyrosine protein dynamics in cell membrane rafts of sphingosine-1-phosphate-stimulated human endothelium: role in barrier enhancement. |
2009 |
Cell. Signal. |
pmid:19755153
|
Brindley DN and Pilquil C |
Lipid phosphate phosphatases and signaling. |
2009 |
J. Lipid Res. |
pmid:19066402
|
Kennedy S et al. |
Targeting sphingosine-1-phosphate signalling for cardioprotection. |
2009 |
Curr Opin Pharmacol |
pmid:19070545
|
Kirby RJ et al. |
Dynamic regulation of sphingosine-1-phosphate homeostasis during development of mouse metanephric kidney. |
2009 |
Am. J. Physiol. Renal Physiol. |
pmid:19073640
|
Kawahara A et al. |
The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors. |
2009 |
Science |
pmid:19074308
|
Lee JF et al. |
Balance of S1P1 and S1P2 signaling regulates peripheral microvascular permeability in rat cremaster muscle vasculature. |
2009 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:19011048
|
Karliner JS |
Sphingosine kinase regulation and cardioprotection. |
2009 |
Cardiovasc. Res. |
pmid:19017750
|
Hashimoto T et al. |
Sphingosine kinase is induced in mouse 3T3-L1 cells and promotes adipogenesis. |
2009 |
J. Lipid Res. |
pmid:19020339
|
Maeurer C et al. |
Sphingosine-1-phosphate induced mTOR-activation is mediated by the E3-ubiquitin ligase PAM. |
2009 |
Cell. Signal. |
pmid:19000755
|
Ikeda H et al. |
Sphingosine 1-phosphate regulates regeneration and fibrosis after liver injury via sphingosine 1-phosphate receptor 2. |
2009 |
J. Lipid Res. |
pmid:18955732
|
Ranty ML et al. |
Ceramide production associated with retinal apoptosis after retinal detachment. |
2009 |
Graefes Arch. Clin. Exp. Ophthalmol. |
pmid:18958490
|
Young N et al. |
Sphingosine-1-phosphate regulates glioblastoma cell invasiveness through the urokinase plasminogen activator system and CCN1/Cyr61. |
2009 |
Mol. Cancer Res. |
pmid:19147534
|
Weis N et al. |
Heme oxygenase-1 contributes to an alternative macrophage activation profile induced by apoptotic cell supernatants. |
2009 |
Mol. Biol. Cell |
pmid:19129475
|
Li MH et al. |
S1P/S1P1 signaling stimulates cell migration and invasion in Wilms tumor. |
2009 |
Cancer Lett. |
pmid:19131156
|
Gérard A et al. |
The Rac activator Tiam1 controls efficient T-cell trafficking and route of transendothelial migration. |
2009 |
Blood |
pmid:19139083
|
Li X et al. |
Fenretinide inhibits myeloma cell growth, osteoclastogenesis and osteoclast viability. |
2009 |
Cancer Lett. |
pmid:19446953
|
Sim-Selley LJ et al. |
Sphingosine-1-phosphate receptors mediate neuromodulatory functions in the CNS. |
2009 |
J. Neurochem. |
pmid:19493165
|
Malchinkhuu E et al. |
Role of Rap1B and tumor suppressor PTEN in the negative regulation of lysophosphatidic acid--induced migration by isoproterenol in glioma cells. |
2009 |
Mol. Biol. Cell |
pmid:19864456
|
Monier A et al. |
Horizontal gene transfer of an entire metabolic pathway between a eukaryotic alga and its DNA virus. |
2009 |
Genome Res. |
pmid:19451591
|
Morris AJ et al. |
Blood relatives: dynamic regulation of bioactive lysophosphatidic acid and sphingosine-1-phosphate metabolism in the circulation. |
2009 |
Trends Cardiovasc. Med. |
pmid:19818950
|
O'Brien N et al. |
Production and characterization of monoclonal anti-sphingosine-1-phosphate antibodies. |
2009 |
J. Lipid Res. |
pmid:19509417
|
Tachikawa M et al. |
Lysophospholipids enhance taurine release from rat retinal vascular endothelial cells under hypoosmotic stress. |
2009 |
Microvasc. Res. |
pmid:19804786
|
Minamitani C et al. |
Involvement of Rho-kinase in sphingosine 1-phosphate-stimulated HSP27 induction in osteoblasts. |
2009 |
Int. J. Mol. Med. |
pmid:19513538
|
Liu X et al. |
Effect of sphingosine 1-phosphate on morphological and functional responses in endothelia and venules after scalding injury. |
2009 |
Burns |
pmid:19520517
|
Okajima F et al. |
[Role of S1P in the lipoprotein-induced actions and their signaling mechanism]. |
2009 |
Seikagaku |
pmid:19522297
|
Chang CL et al. |
S1P(5) is required for sphingosine 1-phosphate-induced autophagy in human prostate cancer PC-3 cells. |
2009 |
Am. J. Physiol., Cell Physiol. |
pmid:19474291
|
Schulz C et al. |
Trafficking of murine hematopoietic stem and progenitor cells in health and vascular disease. |
2009 |
Microcirculation |
pmid:19479622
|
Kimber I et al. |
Langerhans cell migration: not necessarily always at the center of the skin sensitization universe. |
2009 |
J. Invest. Dermatol. |
pmid:19603050
|
Pyne NJ et al. |
New aspects of sphingosine 1-phosphate signaling in mammalian cells. |
2009 |
Adv. Enzyme Regul. |
pmid:19534035
|
Price MM et al. |
Sphingosine-1-phosphate induces development of functionally mature chymase-expressing human mast cells from hematopoietic progenitors. |
2009 |
FASEB J. |
pmid:19535686
|
Nixon GF |
Sphingolipids in inflammation: pathological implications and potential therapeutic targets. |
2009 |
Br. J. Pharmacol. |
pmid:19563535
|
Taniguchi K et al. |
Sprouty4 deficiency potentiates Ras-independent angiogenic signals and tumor growth. |
2009 |
Cancer Sci. |
pmid:19493272
|
Knapp M et al. |
Plasma sphingosine-1-phosphate concentration is reduced in patients with myocardial infarction. |
2009 |
Med. Sci. Monit. |
pmid:19721401
|
Ren S et al. |
Transforming growth factor-beta2 upregulates sphingosine kinase-1 activity, which in turn attenuates the fibrotic response to TGF-beta2 by impeding CTGF expression. |
2009 |
Kidney Int. |
pmid:19657322
|
Grabski AD et al. |
Sphingosine-1-phosphate receptor-2 regulates expression of smooth muscle alpha-actin after arterial injury. |
2009 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:19608972
|
Weigert A et al. |
Sphingosine kinase 2 deficient tumor xenografts show impaired growth and fail to polarize macrophages towards an anti-inflammatory phenotype. |
2009 |
Int. J. Cancer |
pmid:19618460
|
Li C et al. |
Homing of bone marrow mesenchymal stem cells mediated by sphingosine 1-phosphate contributes to liver fibrosis. |
2009 |
J. Hepatol. |
pmid:19398237
|
Guzmán-Hernández ML et al. |
Differential inhibitor of Gbetagamma signaling to AKT and ERK derived from phosducin-like protein: effect on sphingosine 1-phosphate-induced endothelial cell migration and in vitro angiogenesis. |
2009 |
J. Biol. Chem. |
pmid:19403526
|
Michaud MD et al. |
Sphingosine-1-phosphate: a novel nonhypoxic activator of hypoxia-inducible factor-1 in vascular cells. |
2009 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:19423865
|
Mullershausen F et al. |
Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors. |
2009 |
Nat. Chem. Biol. |
pmid:19430484
|
Tao R et al. |
Cardiomyocyte S1P1 receptor-mediated extracellular signal-related kinase signaling and desensitization. |
2009 |
J. Cardiovasc. Pharmacol. |
pmid:19433984
|
Yang G et al. |
Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome. |
2009 |
Am. J. Physiol. Endocrinol. Metab. |
pmid:19435851
|
Yin H et al. |
Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay. |
2009 |
J. Biol. Chem. |
pmid:19286662
|
Hofmann U et al. |
Protective effects of sphingosine-1-phosphate receptor agonist treatment after myocardial ischaemia-reperfusion. |
2009 |
Cardiovasc. Res. |
pmid:19416991
|
Ader I et al. |
When the sphingosine kinase 1/sphingosine 1-phosphate pathway meets hypoxia signaling: new targets for cancer therapy. |
2009 |
Cancer Res. |
pmid:19383898
|
Wetter JA et al. |
Utilization of the Tango beta-arrestin recruitment technology for cell-based EDG receptor assay development and interrogation. |
2009 |
J Biomol Screen |
pmid:19726785
|
Okada T et al. |
Sphingosine kinase/sphingosine 1-phosphate signalling in central nervous system. |
2009 |
Cell. Signal. |
pmid:18694820
|
Foster DJ et al. |
Muscarinic receptor regulation of osmosensitive taurine transport in human SH-SY5Y neuroblastoma cells. |
2009 |
J. Neurochem. |
pmid:19012745
|
Hla T |
Plugging vascular leak by sphingosine kinase from bone marrow progenitor cells. |
2009 |
Circ. Res. |
pmid:19797192
|
Gratschev D et al. |
Sphingosine kinase as a regulator of calcium entry through autocrine sphingosine 1-phosphate signaling in thyroid FRTL-5 cells. |
2009 |
Endocrinology |
pmid:19797403
|
Xiang Y et al. |
Discovery of novel sphingosine kinase 1 inhibitors. |
2009 |
Bioorg. Med. Chem. Lett. |
pmid:19800228
|
Espinosa Cervantes R |
[Sphingolipids in embryonic implantation]. |
2009 |
Ginecol Obstet Mex |
pmid:19899433
|
Okajima F et al. |
Anti-atherogenic actions of high-density lipoprotein through sphingosine 1-phosphate receptors and scavenger receptor class B type I. |
2009 |
Endocr. J. |
pmid:18753704
|
Brinkmann V |
FTY720 (fingolimod) in Multiple Sclerosis: therapeutic effects in the immune and the central nervous system. |
2009 |
Br. J. Pharmacol. |
pmid:19814729
|
Wojciak JM et al. |
The crystal structure of sphingosine-1-phosphate in complex with a Fab fragment reveals metal bridging of an antibody and its antigen. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19815502
|
Jacobson JR |
Pharmacologic therapies on the horizon for acute lung injury/acute respiratory distress syndrome. |
2009 |
J. Investig. Med. |
pmid:19820408
|
Jenne CN et al. |
T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow. |
2009 |
J. Exp. Med. |
pmid:19808259
|
Long DA and Price KL |
Sphingosine kinase-1: a potential mediator of renal fibrosis. |
2009 |
Kidney Int. |
pmid:19789541
|
Heo K et al. |
Sphingosine 1-phosphate induces vascular endothelial growth factor expression in endothelial cells. |
2009 |
BMB Rep |
pmid:19874715
|
Jongsma M et al. |
Different response patterns of several ligands at the sphingosine-1-phosphate receptor subtype 3 (S1P(3)). |
2009 |
Br. J. Pharmacol. |
pmid:19309361
|
Bedia C et al. |
Synthesis of a fluorogenic analogue of sphingosine-1-phosphate and its use to determine sphingosine-1-phosphate lyase activity. |
2009 |
Chembiochem |
pmid:19226506
|
Rodgers A et al. |
Sphingosine 1-phosphate regulation of extracellular signal-regulated kinase-1/2 in embryonic stem cells. |
2009 |
Stem Cells Dev. |
pmid:19228106
|
Gellings Lowe N et al. |
Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor-beta-stimulated collagen production by cardiac fibroblasts. |
2009 |
Cardiovasc. Res. |
pmid:19228708
|
Garcia JG |
Concepts in microvascular endothelial barrier regulation in health and disease. |
2009 |
Microvasc. Res. |
pmid:19232241
|
Igarashi J and Michel T |
Sphingosine-1-phosphate and modulation of vascular tone. |
2009 |
Cardiovasc. Res. |
pmid:19233865
|
Sattler K and Levkau B |
Sphingosine-1-phosphate as a mediator of high-density lipoprotein effects in cardiovascular protection. |
2009 |
Cardiovasc. Res. |
pmid:19233866
|
Ishii M et al. |
Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis. |
2009 |
Nature |
pmid:19204730
|
Zhang ZY et al. |
FTY720 attenuates lesional interleukin-17(+) cell accumulation in rat experimental autoimmune neuritis. |
2009 |
Neuropathol. Appl. Neurobiol. |
pmid:19207263
|
Gillies L et al. |
The sphingosine 1-phosphate receptor 5 and sphingosine kinases 1 and 2 are localised in centrosomes: possible role in regulating cell division. |
2009 |
Cell. Signal. |
pmid:19211033
|
Sensken SC and Gräler MH |
[Sphingolipids and their medical impact]. |
2009 |
Dtsch. Med. Wochenschr. |
pmid:19180419
|
Karliner JS |
Sphingosine kinase and sphingosine 1-phosphate in cardioprotection. |
2009 |
J. Cardiovasc. Pharmacol. |
pmid:19247197
|
Bandhuvula P et al. |
Sphingosine 1-phosphate lyase enzyme assay using a BODIPY-labeled substrate. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19250638
|
Pasquaré SJ et al. |
Age-related changes in the metabolization of phosphatidic acid in rat cerebral cortex synaptosomes. |
2009 |
Arch. Biochem. Biophys. |
pmid:19691145
|
Hagen N et al. |
Subcellular origin of sphingosine 1-phosphate is essential for its toxic effect in lyase-deficient neurons. |
2009 |
J. Biol. Chem. |
pmid:19251691
|
Sandhu KS et al. |
Regional heterogeneity in expression of the sphingosine-1-phosphate pathway in the female rat lower urinary tract. |
2009 |
Am. J. Obstet. Gynecol. |
pmid:19254791
|
Valverde O et al. |
GPR3 receptor, a novel actor in the emotional-like responses. |
2009 |
PLoS ONE |
pmid:19259266
|
Chien CC et al. |
Activation of telomerase and cyclooxygenase-2 in PDGF and FGF inhibition of C2-ceramide-induced apoptosis. |
2009 |
J. Cell. Physiol. |
pmid:18932216
|
Estrada R et al. |
Ligand-induced nuclear translocation of S1P(1) receptors mediates Cyr61 and CTGF transcription in endothelial cells. |
2009 |
Histochem. Cell Biol. |
pmid:18936953
|
Maceyka M et al. |
Sphingosine-1-phosphate: the Swiss army knife of sphingolipid signaling. |
2009 |
J. Lipid Res. |
pmid:18987387
|
Xu Y et al. |
Lipid generation and signaling in ovarian cancer. |
2009 |
Cancer Treat. Res. |
pmid:19763440
|