| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pulmonary Fibrosis | D011658 | 24 associated lipids |
Sphingosine 1-phosphate
Sphingosine 1-phosphate is a lipid of Sphingolipids (SP) class. Sphingosine 1-phosphate is associated with abnormalities such as Infection, Painful Bladder Syndrome, Atherosclerosis, Hyperglycemia and Rheumatoid Arthritis. The involved functions are known as Phosphorylation, Regulation, enzyme activity, Energy Absorption and Vascular Permeability. Sphingosine 1-phosphate often locates in Endothelium, Tissue membrane, Vascular System, Protoplasm and Microfilaments. The associated genes with Sphingosine 1-phosphate are MBTPS1 gene, FBXL15 gene, TEK gene, NTRK1 gene and Gene Family. The related lipids are Promega, Lipopolysaccharides, lysophosphatidic acid, Lysophosphatidylcholines and Lysophospholipids. The related experimental models are Knock-out, Mouse Model, Transgenic Model, Disease model and Experimental Autoimmune Encephalomyelitis.
Cross Reference
Introduction
To understand associated biological information of Sphingosine 1-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Sphingosine 1-phosphate?
Sphingosine 1-phosphate is suspected in Lymphopenia, Ischemia, Infection, Atherosclerosis, Multiple Sclerosis, Asthma and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Sphingosine 1-phosphate
PubChem Associated disorders and diseases
What pathways are associated with Sphingosine 1-phosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Sphingosine 1-phosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Sphingosine 1-phosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Sphingosine 1-phosphate?
Knock-out
Knock-out are used in the study 'Sphingosine 1-phosphate-dependent trafficking of peritoneal B cells requires functional NFkappaB-inducing kinase in stromal cells.' (Kunisawa J et al., 2008), Knock-out are used in the study 'Connective tissue growth factor (CTGF/CCN2) mediates angiogenic effect of S1P in human dermal microvascular endothelial cells.' (Markiewicz M et al., 2011), Knock-out are used in the study 'Chasing sphingosine-1-phosphate, a lipid mediator for cardiomyocyte survival.' (Yang Q, 2007), Knock-out are used in the study 'Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function.' (Idzko M et al., 2006) and Knock-out are used in the study 'Platelet endothelial cell adhesion molecule-1 modulates endothelial cell motility through the small G-protein Rho.' (Gratzinger D et al., 2003).
Mouse Model
Mouse Model are used in the study 'Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: role of cortactin.' (Arce FT et al., 2008), Mouse Model are used in the study 'Sequential delivery of vascular endothelial growth factor and sphingosine 1-phosphate for angiogenesis.' (Tengood JE et al., 2010), Mouse Model are used in the study 'S1P(5) is required for sphingosine 1-phosphate-induced autophagy in human prostate cancer PC-3 cells.' (Chang CL et al., 2009), Mouse Model are used in the study 'Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.' (Hughes JE et al., 2008) and Mouse Model are used in the study 'The alliance of sphingosine-1-phosphate and its receptors in immunity.' (Rivera J et al., 2008).
Transgenic Model
Transgenic Model are used in the study 'Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation.' (Augé N et al., 2004), Transgenic Model are used in the study 'Sphingosine-1-phosphate antibodies as potential agents in the treatment of cancer and age-related macular degeneration.' (Sabbadini RA, 2011) and Transgenic Model are used in the study 'Still benched on its way to the bedside: sphingosine kinase 1 as an emerging target in cancer chemotherapy.' (Gault CR and Obeid LM, 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Sphingosine 1-phosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Stradner MH et al. | Spingosine-1-phosphate stimulates proliferation and counteracts interleukin-1 induced nitric oxide formation in articular chondrocytes. | 2008 | Osteoarthr. Cartil. | pmid:17703957 |
| Wacker BK et al. | Endothelial cell migration on RGD-peptide-containing PEG hydrogels in the presence of sphingosine 1-phosphate. | 2008 | Biophys. J. | pmid:17827231 |
| Provençal M et al. | Tissue factor pathway inhibitor (TFPI) interferes with endothelial cell migration by inhibition of both the Erk pathway and focal adhesion proteins. | 2008 | Thromb. Haemost. | pmid:18327407 |
| Beyer T and Meyer-Hermann M | Mechanisms of organogenesis of primary lymphoid follicles. | 2008 | Int. Immunol. | pmid:18334502 |
| Sensken SC et al. | Selective activation of G alpha i mediated signalling of S1P3 by FTY720-phosphate. | 2008 | Cell. Signal. | pmid:18313900 |
| Kunisawa J et al. | Sphingosine 1-phosphate-dependent trafficking of peritoneal B cells requires functional NFkappaB-inducing kinase in stromal cells. | 2008 | Blood | pmid:18292290 |
| Malchinkhuu E et al. | S1P(2) receptors mediate inhibition of glioma cell migration through Rho signaling pathways independent of PTEN. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18088600 |
| Meacci E et al. | Sphingosine kinase activity is required for myogenic differentiation of C2C12 myoblasts. | 2008 | J. Cell. Physiol. | pmid:17654519 |
| Gohda M et al. | Sphingosine 1-phosphate regulates the egress of IgA plasmablasts from Peyer's patches for intestinal IgA responses. | 2008 | J. Immunol. | pmid:18390715 |
| Lichte K et al. | Lysophospholipid receptor-mediated calcium signaling in human keratinocytes. | 2008 | J. Invest. Dermatol. | pmid:18172456 |
| Avery K et al. | Sphingosine-1-phosphate mediates transcriptional regulation of key targets associated with survival, proliferation, and pluripotency in human embryonic stem cells. | 2008 | Stem Cells Dev. | pmid:18393631 |
| Eskan MA et al. | TLR4 and S1P receptors cooperate to enhance inflammatory cytokine production in human gingival epithelial cells. | 2008 | Eur. J. Immunol. | pmid:18395849 |
| Krump-Konvalinkova V et al. | FTY720 inhibits S1P-mediated endothelial healing: relationship to S1P1-receptor surface expression. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18402775 |
| Olivera A | Unraveling the complexities of sphingosine-1-phosphate function: the mast cell model. | 2008 | Prostaglandins Other Lipid Mediat. | pmid:18403224 |
| Sefcik LS et al. | Sustained release of sphingosine 1-phosphate for therapeutic arteriogenesis and bone tissue engineering. | 2008 | Biomaterials | pmid:18405965 |
| Arce FT et al. | Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: role of cortactin. | 2008 | Biophys. J. | pmid:18408039 |
| Goetzl EJ et al. | Regulation of the roles of sphingosine 1-phosphate and its type 1 G protein-coupled receptor in T cell immunity and autoimmunity. | 2008 | Biochim. Biophys. Acta | pmid:18381082 |
| Hong JH et al. | K6PC-5, a direct activator of sphingosine kinase 1, promotes epidermal differentiation through intracellular Ca2+ signaling. | 2008 | J. Invest. Dermatol. | pmid:18385762 |
| Lebman DA and Spiegel S | Cross-talk at the crossroads of sphingosine-1-phosphate, growth factors, and cytokine signaling. | 2008 | J. Lipid Res. | pmid:18387885 |
| Nishiuma T et al. | Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model. | 2008 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:18359884 |
| Chung FY et al. | Signaling mechanisms of sphingosine 1-phosphate-induced ERK1/2 activation in cultured feline esophageal smooth muscle cells. | 2008 | Arch. Pharm. Res. | pmid:19023540 |
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| Jiang H et al. | Distinguishing fibroblast promigratory and procontractile growth factor environments in 3-D collagen matrices. | 2008 | FASEB J. | pmid:18272655 |
| Valentine WJ et al. | Subtype-specific residues involved in ligand activation of the endothelial differentiation gene family lysophosphatidic acid receptors. | 2008 | J. Biol. Chem. | pmid:18316373 |
| Borges S et al. | Discrete influx events refill depleted Ca2+ stores in a chick retinal neuron. | 2008 | J. Physiol. (Lond.) | pmid:18033816 |
| Szczepaniak WS et al. | Sphingosine 1-phosphate rescues canine LPS-induced acute lung injury and alters systemic inflammatory cytokine production in vivo. | 2008 | Transl Res | pmid:19010292 |
| Huang YT et al. | Sphingosine 1-phosphate induces platelet/endothelial cell adhesion molecule-1 phosphorylation in human endothelial cells through cSrc and Fyn. | 2008 | Cell. Signal. | pmid:18502612 |
| Chen LY et al. | Cytosolic phospholipase A2alpha activation induced by S1P is mediated by the S1P3 receptor in lung epithelial cells. | 2008 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:18502815 |
| Wamhoff BR et al. | Sphingosine-1-phosphate receptor subtypes differentially regulate smooth muscle cell phenotype. | 2008 | Arterioscler. Thromb. Vasc. Biol. | pmid:18535287 |
| Rapizzi E et al. | Sphingosine 1-phosphate differentially regulates proliferation of C2C12 reserve cells and myoblasts. | 2008 | Mol. Cell. Biochem. | pmid:18454302 |
| Son DJ et al. | Enhanced release of sphingosine-1-phosphate from hypercholesterolemic platelets: role in development of hypercholesterolemic atherosclerosis. | 2008 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18571912 |
| Peavy RD and Metcalfe DD | Understanding the mechanisms of anaphylaxis. | 2008 | Curr Opin Allergy Clin Immunol | pmid:18596587 |
| Cheon S et al. | Sphingosine kinase inhibitor suppresses IL-18-induced interferon-gamma production through inhibition of p38 MAPK activation in human NK cells. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18602364 |
| Ohkawa R et al. | Plasma sphingosine-1-phosphate measurement in healthy subjects: close correlation with red blood cell parameters. | 2008 | Ann. Clin. Biochem. | pmid:18583619 |
| Takuwa Y et al. | Sphingosine-1-phosphate signaling and biological activities in the cardiovascular system. | 2008 | Biochim. Biophys. Acta | pmid:18472021 |
| Rivera J et al. | New insights on mast cell activation via the high affinity receptor for IgE. | 2008 | Adv. Immunol. | pmid:18772004 |
| Westerberg LS et al. | WASP confers selective advantage for specific hematopoietic cell populations and serves a unique role in marginal zone B-cell homeostasis and function. | 2008 | Blood | pmid:18772454 |
| Huang WR et al. | [SphK-1/S1P signal pathway in CML cells]. | 2008 | Zhongguo Shi Yan Xue Ye Xue Za Zhi | pmid:18718048 |
| Serrano-Sanchez M et al. | Signaling pathways involved in sphingosine kinase activation and sphingosine-1-phosphate release in rat myometrium in late pregnancy: role in the induction of cyclooxygenase 2. | 2008 | Endocrinology | pmid:18723875 |
| Ohama T et al. | Sphingosine-1-phosphate enhances IL-1{beta}-induced COX-2 expression in mouse intestinal subepithelial myofibroblasts. | 2008 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:18703638 |
| Kihara A and Igarashi Y | Production and release of sphingosine 1-phosphate and the phosphorylated form of the immunomodulator FTY720. | 2008 | Biochim. Biophys. Acta | pmid:18555808 |
| Kaya H et al. | Does sphingosine-1-phosphate have a protective effect on cyclophosphamide- and irradiation-induced ovarian damage in the rat model? | 2008 | Fertil. Steril. | pmid:17517398 |
| Worrall D et al. | Involvement of sphingosine kinase in plant cell signalling. | 2008 | Plant J. | pmid:18557834 |
| Heller R et al. | Overlapping and distinct roles for PI3Kbeta and gamma isoforms in S1P-induced migration of human and mouse endothelial cells. | 2008 | Cardiovasc. Res. | pmid:18558630 |
| Yan G et al. | Activation of sphingosine kinase-1 mediates induction of endothelial cell proliferation and angiogenesis by epoxyeicosatrienoic acids. | 2008 | Cardiovasc. Res. | pmid:18192241 |
| Fulton D et al. | Agonist-stimulated endothelial nitric oxide synthase activation and vascular relaxation. Role of eNOS phosphorylation at Tyr83. | 2008 | Circ. Res. | pmid:18096817 |
| Nussbaumer P et al. | An efficient, one-pot synthesis of various ceramide 1-phosphates from sphingosine 1-phosphate. | 2008 | Chem. Phys. Lipids | pmid:18039471 |
| Srinivasan S et al. | Sphingosine-1-phosphate reduces CD4+ T-cell activation in type 1 diabetes through regulation of hypoxia-inducible factor short isoform I.1 and CD69. | 2008 | Diabetes | pmid:18003758 |
| Johann AM et al. | Apoptotic cell-derived sphingosine-1-phosphate promotes HuR-dependent cyclooxygenase-2 mRNA stabilization and protein expression. | 2008 | J. Immunol. | pmid:18178864 |
| Oskeritzian CA et al. | Distinct roles of sphingosine kinases 1 and 2 in human mast-cell functions. | 2008 | Blood | pmid:18178871 |
| Oyama O et al. | The lysophospholipid mediator sphingosine-1-phosphate promotes angiogenesis in vivo in ischaemic hindlimbs of mice. | 2008 | Cardiovasc. Res. | pmid:18187460 |
| Patschan S et al. | Lipid mediators of autophagy in stress-induced premature senescence of endothelial cells. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18203850 |
| Eskan MA et al. | Sphingosine 1-phosphate 1 and TLR4 mediate IFN-beta expression in human gingival epithelial cells. | 2008 | J. Immunol. | pmid:18209079 |
| Sekiguchi M et al. | Role of sphingosine 1-phosphate in the pathogenesis of Sjögren's syndrome. | 2008 | J. Immunol. | pmid:18209090 |
| Brunati AM et al. | Cross-talk between PDGF and S1P signalling elucidates the inhibitory effect and potential antifibrotic action of the immunomodulator FTY720 in activated HSC-cultures. | 2008 | Biochim. Biophys. Acta | pmid:18157950 |
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| Vessey DA et al. | Sphingosine can pre- and post-condition heart and utilizes a different mechanism from sphingosine 1-phosphate. | 2008 Mar-Apr | J. Biochem. Mol. Toxicol. | pmid:18418901 |
| Limaye V | The role of sphingosine kinase and sphingosine-1-phosphate in the regulation of endothelial cell biology. | 2008 May-Jun | Endothelium | pmid:18568950 |
| RodrÃguez C et al. | Sphingosine-1-phosphate: A bioactive lipid that confers high-density lipoprotein with vasculoprotection mediated by nitric oxide and prostacyclin. | 2009 | Thromb. Haemost. | pmid:19350109 |
| Formigli L et al. | Regulation of transient receptor potential canonical channel 1 (TRPC1) by sphingosine 1-phosphate in C2C12 myoblasts and its relevance for a role of mechanotransduction in skeletal muscle differentiation. | 2009 | J. Cell. Sci. | pmid:19351713 |
| Li Y and Yu KL | [Advances in thrombin-protease-activated receptor 1-sphingosine 1-phosphate pathway during sepsis]. | 2009 | Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | pmid:19278594 |
| He X et al. | Quantitative analysis of sphingosine-1-phosphate by HPLC after napthalene-2,3-dicarboxaldehyde (NDA) derivatization. | 2009 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19285924 |
| Peyruchaud O | Novel implications for lysophospholipids, lysophosphatidic acid and sphingosine 1-phosphate, as drug targets in cancer. | 2009 | Anticancer Agents Med Chem | pmid:19442039 |
| Kenagy RD et al. | Proliferative capacity of vein graft smooth muscle cells and fibroblasts in vitro correlates with graft stenosis. | 2009 | J. Vasc. Surg. | pmid:19307078 |
| Salinas NR et al. | Lung tumor development in the presence of sphingosine 1-phosphate agonist FTY720. | 2009 | Pathol. Oncol. Res. | pmid:19214784 |
| Tokumura A et al. | Elevated serum levels of arachidonoyl-lysophosphatidic acid and sphingosine 1-phosphate in systemic sclerosis. | 2009 | Int J Med Sci | pmid:19521548 |
| Gibbs TC et al. | Signal transduction responses to lysophosphatidic acid and sphingosine 1-phosphate in human prostate cancer cells. | 2009 | Prostate | pmid:19536794 |
| Lee JF et al. | Balance of S1P1 and S1P2 signaling regulates peripheral microvascular permeability in rat cremaster muscle vasculature. | 2009 | Am. J. Physiol. Heart Circ. Physiol. | pmid:19011048 |
| Karliner JS | Sphingosine kinase regulation and cardioprotection. | 2009 | Cardiovasc. Res. | pmid:19017750 |
| Hashimoto T et al. | Sphingosine kinase is induced in mouse 3T3-L1 cells and promotes adipogenesis. | 2009 | J. Lipid Res. | pmid:19020339 |
| Maeurer C et al. | Sphingosine-1-phosphate induced mTOR-activation is mediated by the E3-ubiquitin ligase PAM. | 2009 | Cell. Signal. | pmid:19000755 |
| Ikeda H et al. | Sphingosine 1-phosphate regulates regeneration and fibrosis after liver injury via sphingosine 1-phosphate receptor 2. | 2009 | J. Lipid Res. | pmid:18955732 |
| Minamitani C et al. | Involvement of Rho-kinase in sphingosine 1-phosphate-stimulated HSP27 induction in osteoblasts. | 2009 | Int. J. Mol. Med. | pmid:19513538 |
| Natsume H et al. | (-)-Epigallocatechin gallate attenuates the induction of HSP27 stimulated by sphingosine 1-phosphate via suppression of phosphatidylinositol 3-kinase/Akt pathway in osteoblasts. | 2009 | Int. J. Mol. Med. | pmid:19578793 |
| Liu X et al. | Effect of sphingosine 1-phosphate on morphological and functional responses in endothelia and venules after scalding injury. | 2009 | Burns | pmid:19520517 |
| Okajima F et al. | [Role of S1P in the lipoprotein-induced actions and their signaling mechanism]. | 2009 | Seikagaku | pmid:19522297 |
| Chang CL et al. | S1P(5) is required for sphingosine 1-phosphate-induced autophagy in human prostate cancer PC-3 cells. | 2009 | Am. J. Physiol., Cell Physiol. | pmid:19474291 |
| Schulz C et al. | Trafficking of murine hematopoietic stem and progenitor cells in health and vascular disease. | 2009 | Microcirculation | pmid:19479622 |
| Hu W et al. | Palmitate increases sphingosine-1-phosphate in C2C12 myotubes via upregulation of sphingosine kinase message and activity. | 2009 | J. Lipid Res. | pmid:19369694 |
| Li C et al. | Homing of bone marrow mesenchymal stem cells mediated by sphingosine 1-phosphate contributes to liver fibrosis. | 2009 | J. Hepatol. | pmid:19398237 |
| Guzmán-Hernández ML et al. | Differential inhibitor of Gbetagamma signaling to AKT and ERK derived from phosducin-like protein: effect on sphingosine 1-phosphate-induced endothelial cell migration and in vitro angiogenesis. | 2009 | J. Biol. Chem. | pmid:19403526 |
| Michaud MD et al. | Sphingosine-1-phosphate: a novel nonhypoxic activator of hypoxia-inducible factor-1 in vascular cells. | 2009 | Arterioscler. Thromb. Vasc. Biol. | pmid:19423865 |
| Mullershausen F et al. | Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors. | 2009 | Nat. Chem. Biol. | pmid:19430484 |
| Tao R et al. | Cardiomyocyte S1P1 receptor-mediated extracellular signal-related kinase signaling and desensitization. | 2009 | J. Cardiovasc. Pharmacol. | pmid:19433984 |
| Yang G et al. | Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome. | 2009 | Am. J. Physiol. Endocrinol. Metab. | pmid:19435851 |
| Hofmann U et al. | Protective effects of sphingosine-1-phosphate receptor agonist treatment after myocardial ischaemia-reperfusion. | 2009 | Cardiovasc. Res. | pmid:19416991 |
| Ader I et al. | When the sphingosine kinase 1/sphingosine 1-phosphate pathway meets hypoxia signaling: new targets for cancer therapy. | 2009 | Cancer Res. | pmid:19383898 |
| Brinkmann V | FTY720 (fingolimod) in Multiple Sclerosis: therapeutic effects in the immune and the central nervous system. | 2009 | Br. J. Pharmacol. | pmid:19814729 |
| Wojciak JM et al. | The crystal structure of sphingosine-1-phosphate in complex with a Fab fragment reveals metal bridging of an antibody and its antigen. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19815502 |
| Jacobson JR | Pharmacologic therapies on the horizon for acute lung injury/acute respiratory distress syndrome. | 2009 | J. Investig. Med. | pmid:19820408 |
| Bedia C et al. | Synthesis of a fluorogenic analogue of sphingosine-1-phosphate and its use to determine sphingosine-1-phosphate lyase activity. | 2009 | Chembiochem | pmid:19226506 |
| Rodgers A et al. | Sphingosine 1-phosphate regulation of extracellular signal-regulated kinase-1/2 in embryonic stem cells. | 2009 | Stem Cells Dev. | pmid:19228106 |
| Gellings Lowe N et al. | Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor-beta-stimulated collagen production by cardiac fibroblasts. | 2009 | Cardiovasc. Res. | pmid:19228708 |
| Herr B et al. | The supernatant of apoptotic cells causes transcriptional activation of hypoxia-inducible factor-1alpha in macrophages via sphingosine-1-phosphate and transforming growth factor-beta. | 2009 | Blood | pmid:19549990 |
| Valverde O et al. | GPR3 receptor, a novel actor in the emotional-like responses. | 2009 | PLoS ONE | pmid:19259266 |
| Kobayashi N et al. | Characterization of the ATP-dependent sphingosine 1-phosphate transporter in rat erythrocytes. | 2009 | J. Biol. Chem. | pmid:19531471 |
| Chien CC et al. | Activation of telomerase and cyclooxygenase-2 in PDGF and FGF inhibition of C2-ceramide-induced apoptosis. | 2009 | J. Cell. Physiol. | pmid:18932216 |
| Estrada R et al. | Ligand-induced nuclear translocation of S1P(1) receptors mediates Cyr61 and CTGF transcription in endothelial cells. | 2009 | Histochem. Cell Biol. | pmid:18936953 |
| Maceyka M et al. | Sphingosine-1-phosphate: the Swiss army knife of sphingolipid signaling. | 2009 | J. Lipid Res. | pmid:18987387 |