Pyne S and Pyne NJ |
Sphingosine 1-phosphate signalling in mammalian cells. |
2000 |
Biochem. J. |
pmid:10880336
|
Sharma C et al. |
Inhibition of Ca2+ release channel (ryanodine receptor) activity by sphingolipid bases: mechanism of action. |
2000 |
Chem. Phys. Lipids |
pmid:10660207
|
Vasta V et al. |
Sphingosine 1-phosphate induces arachidonic acid mobilization in A549 human lung adenocarcinoma cells. |
2000 |
Biochim. Biophys. Acta |
pmid:10601704
|
An S et al. |
Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5. |
2000 |
J. Biol. Chem. |
pmid:10617617
|
Pyne S and Pyne N |
Sphingosine 1-phosphate signalling via the endothelial differentiation gene family of G-protein-coupled receptors. |
2000 |
Pharmacol. Ther. |
pmid:11150592
|
Conway A et al. |
Ceramide-dependent regulation of p42/p44 mitogen-activated protein kinase and c-Jun N-terminal-directed protein kinase in cultured airway smooth muscle cells. |
2000 |
Cell. Signal. |
pmid:11152959
|
Olivera A et al. |
Assaying sphingosine kinase activity. |
2000 |
Meth. Enzymol. |
pmid:10563328
|
Brindley DN et al. |
Analysis of ceramide 1-phosphate and sphingosine-1-phosphate phosphatase activities. |
2000 |
Meth. Enzymol. |
pmid:10563330
|
Rümenapp U et al. |
Sphingolipid receptor signaling and function in human bladder carcinoma cells: inhibition of LPA- but enhancement of thrombin-stimulated cell motility. |
2000 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:10651140
|
Lee OH et al. |
Sphingosine 1-phosphate stimulates tyrosine phosphorylation of focal adhesion kinase and chemotactic motility of endothelial cells via the G(i) protein-linked phospholipase C pathway. |
2000 |
Biochem. Biophys. Res. Commun. |
pmid:10652210
|
Sato K et al. |
Differential roles of Edg-1 and Edg-5, sphingosine 1-phosphate receptors, in the signaling pathways in C6 glioma cells. |
2000 |
Brain Res. Mol. Brain Res. |
pmid:11146117
|
Hla T et al. |
Sphingosine-1-phosphate signaling via the EDG-1 family of G-protein-coupled receptors. |
2000 |
Ann. N. Y. Acad. Sci. |
pmid:10818438
|
Spiegel S |
Sphingosine 1-phosphate: a ligand for the EDG-1 family of G-protein-coupled receptors. |
2000 |
Ann. N. Y. Acad. Sci. |
pmid:10818441
|
Ancellin N and Hla T |
Switching intracellular signaling pathways to study sphingosine 1-phosphate receptors. |
2000 |
Ann. N. Y. Acad. Sci. |
pmid:10818459
|
Yamamura S et al. |
Sphingosine-1-phosphate inhibits haptotactic motility by overproduction of focal adhesion sites in B16 melanoma cells through EDG-induced activation of Rho. |
2000 |
Ann. N. Y. Acad. Sci. |
pmid:10818470
|
Gallois C et al. |
Endothelin-1 stimulates sphingosine kinase in human hepatic stellate cells. A novel role for sphingosine-1-P as a mediator of growth inhibition. |
2000 |
Ann. N. Y. Acad. Sci. |
pmid:10818472
|
Gennero I et al. |
Effect of sphingosine-1-phosphate and analogues of lysophosphatidic acid on mesangial cell proliferation. |
2000 |
Ann. N. Y. Acad. Sci. |
pmid:10818478
|
Alessenko AV |
The role of sphingomyelin cycle metabolites in transduction of signals of cell proliferation, differentiation and death. |
2000 |
Membr Cell Biol |
pmid:10779176
|
Miura Y et al. |
Rho-mediated phosphorylation of focal adhesion kinase and myosin light chain in human endothelial cells stimulated with sphingosine 1-phosphate, a bioactive lysophospholipid released from activated platelets. |
2000 |
J. Biochem. |
pmid:10788802
|
Im DS et al. |
Characterization of a novel sphingosine 1-phosphate receptor, Edg-8. |
2000 |
J. Biol. Chem. |
pmid:10799507
|
Goetzl EJ et al. |
Cutting edge: differential constitutive expression of functional receptors for lysophosphatidic acid by human blood lymphocytes. |
2000 |
J. Immunol. |
pmid:10799850
|
Nava VE et al. |
Functional characterization of human sphingosine kinase-1. |
2000 |
FEBS Lett. |
pmid:10802064
|
Spiegel S and Milstien S |
Functions of a new family of sphingosine-1-phosphate receptors. |
2000 |
Biochim. Biophys. Acta |
pmid:10760461
|
Panetti TS et al. |
Sphingosine-1-phosphate and lysophosphatidic acid stimulate endothelial cell migration. |
2000 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:10764666
|
Boguslawski G et al. |
Sphingosylphosphorylcholine induces endothelial cell migration and morphogenesis. |
2000 |
Biochem. Biophys. Res. Commun. |
pmid:10833459
|
Kimura T et al. |
Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3. |
2000 |
Biochem. J. |
pmid:10794715
|
Van Brocklyn JR et al. |
Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6. |
2000 |
Blood |
pmid:10753843
|
English D et al. |
Sphingosine 1-phosphate released from platelets during clotting accounts for the potent endothelial cell chemotactic activity of blood serum and provides a novel link between hemostasis and angiogenesis. |
2000 |
FASEB J. |
pmid:11053247
|
Edsall L et al. |
Enzymatic method for measurement of sphingosine 1-phosphate. |
2000 |
Meth. Enzymol. |
pmid:11070858
|
Sullards MC |
Analysis of sphingomyelin, glucosylceramide, ceramide, sphingosine, and sphingosine 1-phosphate by tandem mass spectrometry. |
2000 |
Meth. Enzymol. |
pmid:11070861
|
Xia P et al. |
An oncogenic role of sphingosine kinase. |
2000 |
Curr. Biol. |
pmid:11114522
|
Okamoto H et al. |
Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3. |
2000 |
Mol. Cell. Biol. |
pmid:11094076
|
Murata N et al. |
Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions. |
2000 |
Biochem. J. |
pmid:11104690
|
Shimizu H et al. |
Sphingosine 1-phosphate stimulates insulin secretion in HIT-T 15 cells and mouse islets. |
2000 |
Endocr. J. |
pmid:11036869
|
MacLennan AJ et al. |
Antisense studies in PC12 cells suggest a role for H218, a sphingosine 1-phosphate receptor, in growth-factor-induced cell-cell interaction and neurite outgrowth. |
2000 |
Dev. Neurosci. |
pmid:10965150
|
Nakajima N et al. |
Expression and characterization of Edg-1 receptors in rat cardiomyocytes: calcium deregulation in response to sphingosine 1-phosphate. |
2000 |
Eur. J. Biochem. |
pmid:10971577
|
Parrill AL et al. |
Identification of Edg1 receptor residues that recognize sphingosine 1-phosphate. |
2000 |
J. Biol. Chem. |
pmid:10982820
|
Davaille J et al. |
Antiproliferative properties of sphingosine 1-phosphate in human hepatic myofibroblasts. A cyclooxygenase-2 mediated pathway. |
2000 |
J. Biol. Chem. |
pmid:10942778
|
Pitson SM et al. |
Expression of a catalytically inactive sphingosine kinase mutant blocks agonist-induced sphingosine kinase activation. A dominant-negative sphingosine kinase. |
2000 |
J. Biol. Chem. |
pmid:10944534
|
Nugent D and Xu Y |
Sphingosine-1-phosphate: characterization of its inhibition of platelet aggregation. |
2000 |
Platelets |
pmid:10938902
|
Young KW et al. |
Effect of dimethylsphingosine on muscarinic M(3) receptor signalling in SH-SY5Y cells. |
2000 |
Eur. J. Pharmacol. |
pmid:10940357
|
Bischoff A et al. |
Sphingosine-1-phosphate and sphingosylphosphorylcholine constrict renal and mesenteric microvessels in vitro. |
2000 |
Br. J. Pharmacol. |
pmid:10952677
|
Bischoff A et al. |
Sphingosine-1-phosphate reduces rat renal and mesenteric blood flow in vivo in a pertussis toxin-sensitive manner. |
2000 |
Br. J. Pharmacol. |
pmid:10952678
|
Shin Y et al. |
Diverse effects of sphingosine on calcium mobilization and influx in differentiated HL-60 cells. |
2000 |
Cell Calcium |
pmid:10859593
|
Alemany R et al. |
Stimulation of sphingosine-1-phosphate formation by the P2Y(2) receptor in HL-60 cells: Ca(2+) requirement and implication in receptor-mediated Ca(2+) mobilization, but not MAP kinase activation. |
2000 |
Mol. Pharmacol. |
pmid:10953041
|
Young KW et al. |
Lysophosphatidic acid-induced Ca2+ mobilization requires intracellular sphingosine 1-phosphate production. Potential involvement of endogenous EDG-4 receptors. |
2000 |
J. Biol. Chem. |
pmid:10954727
|
Peyruchaud O and Mosher DF |
Differential stimulation of signaling pathways initiated by Edg-2 in response to lysophosphatidic acid or sphingosine-1-phosphate. |
2000 |
Cell. Mol. Life Sci. |
pmid:10961347
|
Casper RF and Jurisicova A |
Protecting the female germ line from cancer therapy. |
2000 |
Nat. Med. |
pmid:11017136
|
Morita Y et al. |
Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy. |
2000 |
Nat. Med. |
pmid:11017141
|
Himmel HM et al. |
Evidence for Edg-3 receptor-mediated activation of I(K.ACh) by sphingosine-1-phosphate in human atrial cardiomyocytes. |
2000 |
Mol. Pharmacol. |
pmid:10908314
|
Driever W |
Developmental biology. Bringing two hearts together. |
2000 |
Nature |
pmid:10910341
|
Kupperman E et al. |
A sphingosine-1-phosphate receptor regulates cell migration during vertebrate heart development. |
2000 |
Nature |
pmid:10910360
|
Mandala SM et al. |
Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death. |
2000 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:10859351
|
Meacci E et al. |
Receptor-activated phospholipase D is present in caveolin-3-enriched light membranes of C2C12 myotubes. |
2000 |
FEBS Lett. |
pmid:10802049
|
Murata N et al. |
Quantitative measurement of sphingosine 1-phosphate by radioreceptor-binding assay. |
2000 |
Anal. Biochem. |
pmid:10860507
|
Spiegel S and Milstien S |
Sphingosine-1-phosphate: signaling inside and out. |
2000 |
FEBS Lett. |
pmid:10878250
|
Cooke ME et al. |
Contraction of collagen matrices mediated by alpha2beta1A and alpha(v)beta3 integrins. |
2000 |
J. Cell. Sci. |
pmid:10852817
|
Yanai N et al. |
Sphingosine-1-phosphate and lysophosphatidic acid trigger invasion of primitive hematopoietic cells into stromal cell layers. |
2000 |
Blood |
pmid:10891442
|
Prieschl EE and Baumruker T |
Beyond a structural component: sphingolipids in immunology. |
2000 |
Arch. Immunol. Ther. Exp. (Warsz.) |
pmid:10912620
|
Ikeda H et al. |
Biological activities of novel lipid mediator sphingosine 1-phosphate in rat hepatic stellate cells. |
2000 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:10915638
|
Yamazaki Y et al. |
Edg-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) signaling pathway. |
2000 |
Biochem. Biophys. Res. Commun. |
pmid:10679247
|
Lee H et al. |
Lysophosphatidic acid and sphingosine 1-phosphate stimulate endothelial cell wound healing. |
2000 |
Am. J. Physiol., Cell Physiol. |
pmid:10712250
|
Motohashi K et al. |
Identification of lysophospholipid receptors in human platelets: the relation of two agonists, lysophosphatidic acid and sphingosine 1-phosphate. |
2000 |
FEBS Lett. |
pmid:10692584
|
Sugiyama A et al. |
Sphingosine 1-phosphate induces sinus tachycardia and coronary vasoconstriction in the canine heart. |
2000 |
Cardiovasc. Res. |
pmid:10727660
|
Kozawa O et al. |
Sphingosine 1-phosphate amplifies phosphoinositide hydrolysis stimulated by prostaglandin f2 alpha in osteoblasts: involvement of p38MAP kinase. |
2000 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:10913228
|
Orlati S et al. |
Sphingosine-1-phosphate activates phospholipase D in human airway epithelial cells via a G protein-coupled receptor. |
2000 |
Arch. Biochem. Biophys. |
pmid:10683250
|
Okamoto H et al. |
Sphingosine 1-phosphate stimulates G(i)- and Rho-mediated vascular endothelial cell spreading and migration. |
2000 |
Thromb. Res. |
pmid:10942792
|
Takeshita A et al. |
Selective stimulation by ceramide of the expression of the alpha isoform of retinoic acid and retinoid X receptors in osteoblastic cells. A role of sphingosine 1-phosphate-mediated AP-1 in the ligand-dependent transcriptional activity of these receptors. |
2000 |
J. Biol. Chem. |
pmid:10915783
|
Nanjundan M and Possmayer F |
Characterization of the pulmonary N-ethylmaleimide-insensitive phosphatidate phosphohydrolase. |
2000 Jul-Aug |
Exp. Lung Res. |
pmid:10914334
|
Osawa Y et al. |
TNF-alpha-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes. |
2001 |
J. Immunol. |
pmid:11418646
|
Boujaoude LC et al. |
Cystic fibrosis transmembrane regulator regulates uptake of sphingoid base phosphates and lysophosphatidic acid: modulation of cellular activity of sphingosine 1-phosphate. |
2001 |
J. Biol. Chem. |
pmid:11443135
|
Paik JH et al. |
Sphingosine 1-phosphate-induced endothelial cell migration requires the expression of EDG-1 and EDG-3 receptors and Rho-dependent activation of alpha vbeta3- and beta1-containing integrins. |
2001 |
J. Biol. Chem. |
pmid:11150298
|
Muraki K and Imaizumi Y |
A novel function of sphingosine-1-phosphate to activate a non-selective cation channel in human endothelial cells. |
2001 |
J. Physiol. (Lond.) |
pmid:11731576
|
Lee MJ et al. |
Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis. |
2001 |
Mol. Cell |
pmid:11583630
|
Li G et al. |
Sphingosine-1-phosphate lyase has a central role in the development of Dictyostelium discoideum. |
2001 |
Development |
pmid:11566853
|
Bischoff A et al. |
Nifedipine inhibits sphinogosine-1-phosphate-induced renovascular contraction in vitro and in vivo. |
2001 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:11534858
|
Robert P et al. |
EDG1 receptor stimulation leads to cardiac hypertrophy in rat neonatal myocytes. |
2001 |
J. Mol. Cell. Cardiol. |
pmid:11549339
|
Marletta MA |
Another activation switch for endothelial nitric oxide synthase: why does it have to be so complicated? |
2001 |
Trends Biochem. Sci. |
pmid:11551775
|
Erl W and Siess W |
Sphingosine-1-phosphate and the leading Edg-1 of vascular smooth muscle cells. |
2001 |
Circ. Res. |
pmid:11557732
|
Kluk MJ and Hla T |
Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration. |
2001 |
Circ. Res. |
pmid:11557736
|
Meacci E et al. |
Dual regulation of sphingosine 1-phosphate-induced phospholipase D activity through RhoA and protein kinase C-alpha in C2C12 myoblasts. |
2001 |
Cell. Signal. |
pmid:11483412
|
Pébay A et al. |
Sphingosine-1-phosphate induces proliferation of astrocytes: regulation by intracellular signalling cascades. |
2001 |
Eur. J. Neurosci. |
pmid:11467306
|
Brownlee C |
Intracellular signalling: sphingosine-1-phosphate branches out. |
2001 |
Curr. Biol. |
pmid:11470429
|
Igarashi J and Michel T |
Sphingosine 1-phosphate and isoform-specific activation of phosphoinositide 3-kinase beta. Evidence for divergence and convergence of receptor-regulated endothelial nitric-oxide synthase signaling pathways. |
2001 |
J. Biol. Chem. |
pmid:11470796
|
Garcia JG et al. |
Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement. |
2001 |
J. Clin. Invest. |
pmid:11544274
|
Nadal A et al. |
Glial cell responses to lipids bound to albumin in serum and plasma. |
2001 |
Prog. Brain Res. |
pmid:11545003
|
Tamama K et al. |
Extracellular mechanism through the Edg family of receptors might be responsible for sphingosine-1-phosphate-induced regulation of DNA synthesis and migration of rat aortic smooth-muscle cells. |
2001 |
Biochem. J. |
pmid:11115407
|
Tosaka M et al. |
Sphingosine 1-phosphate contracts canine basilar arteries in vitro and in vivo: possible role in pathogenesis of cerebral vasospasm. |
2001 |
Stroke |
pmid:11739995
|
Ohanian J and Ohanian V |
Sphingolipids in mammalian cell signalling. |
2001 |
Cell. Mol. Life Sci. |
pmid:11814056
|
Wang DA et al. |
A single amino acid determines lysophospholipid specificity of the S1P1 (EDG1) and LPA1 (EDG2) phospholipid growth factor receptors. |
2001 |
J. Biol. Chem. |
pmid:11604399
|
Andor A et al. |
YopE of Yersinia, a GAP for Rho GTPases, selectively modulates Rac-dependent actin structures in endothelial cells. |
2001 |
Cell. Microbiol. |
pmid:11298653
|
Ammit AJ et al. |
Sphingosine 1-phosphate modulates human airway smooth muscle cell functions that promote inflammation and airway remodeling in asthma. |
2001 |
FASEB J. |
pmid:11344091
|
Yatomi Y et al. |
Sphingosine 1-phosphate: synthesis and release. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11324700
|
Goetzl EJ |
Pleiotypic mechanisms of cellular responses to biologically active lysophospholipids. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11324701
|
Liu F et al. |
Differential regulation of sphingosine-1-phosphate- and VEGF-induced endothelial cell chemotaxis. Involvement of G(ialpha2)-linked Rho kinase activity. |
2001 |
Am. J. Respir. Cell Mol. Biol. |
pmid:11415936
|
Olorundare OE et al. |
Assembly of a fibronectin matrix by adherent platelets stimulated by lysophosphatidic acid and other agonists. |
2001 |
Blood |
pmid:11418470
|
Ruwisch L et al. |
An improved high-performance liquid chromatographic method for the determination of sphingosine-1-phosphate in complex biological materials. |
2001 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:11284453
|
Aas V et al. |
Fibronectin promotes calcium signaling by interferon-gamma in human neutrophils via G-protein and sphingosine kinase-dependent mechanisms. |
2001 |
Cell Commun. Adhes. |
pmid:11936187
|
Banno Y et al. |
Involvement of phospholipase D in sphingosine 1-phosphate-induced activation of phosphatidylinositol 3-kinase and Akt in Chinese hamster ovary cells overexpressing EDG3. |
2001 |
J. Biol. Chem. |
pmid:11468290
|
Blaukat A and Dikic I |
Activation of sphingosine kinase by the bradykinin B2 receptor and its implication in regulation of the ERK/MAP kinase pathway. |
2001 |
Biol. Chem. |
pmid:11258664
|