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Sphingosine-1-phosphate and other lipid mediators generated by mast cells as critical players in allergy and mast cell function. |
2016 |
Eur. J. Pharmacol. |
pmid:25941085
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Bigaud M et al. |
Pathophysiological Consequences of a Break in S1P1-Dependent Homeostasis of Vascular Permeability Revealed by S1P1 Competitive Antagonism. |
2016 |
PLoS ONE |
pmid:28005953
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Surya VN et al. |
Sphingosine 1-phosphate receptor 1 regulates the directional migration of lymphatic endothelial cells in response to fluid shear stress. |
2016 |
J R Soc Interface |
pmid:27974574
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Kasbi-Chadli F et al. |
Direct and maternal n-3 long-chain polyunsaturated fatty acid supplementation improved triglyceridemia and glycemia through the regulation of hepatic and muscle sphingolipid synthesis in offspring hamsters fed a high-fat diet. |
2016 |
Eur J Nutr |
pmid:25787885
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Hemdan NY et al. |
Modulating sphingosine 1-phosphate signaling with DOP or FTY720 alleviates vascular and immune defects in mouse sepsis. |
2016 |
Eur. J. Immunol. |
pmid:27683081
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Sphingosine 1-phosphate in metabolic syndrome (Review). |
2016 |
Int. J. Mol. Med. |
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Differential Effects of Long Term FTY720 Treatment on Endothelial versus Smooth Muscle Cell Signaling to S1P in Rat Mesenteric Arteries. |
2016 |
PLoS ONE |
pmid:27583547
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Chen C et al. |
Polydatin attenuates AGEs-induced upregulation of fibronectin and ICAM-1 in rat glomerular mesangial cells and db/db diabetic mice kidneys by inhibiting the activation of the SphK1-S1P signaling pathway. |
2016 |
Mol. Cell. Endocrinol. |
pmid:26948947
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Tsai HC and Han MH |
Sphingosine-1-Phosphate (S1P) and S1P Signaling Pathway: Therapeutic Targets in Autoimmunity and Inflammation. |
2016 |
Drugs |
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Yang Z et al. |
TGR5 activation suppressed S1P/S1P2 signaling and resisted high glucose-induced fibrosis in glomerular mesangial cells. |
2016 |
Pharmacol. Res. |
pmid:27317945
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Cantalupo A and Di Lorenzo A |
S1P Signaling and De Novo Biosynthesis in Blood Pressure Homeostasis. |
2016 |
J. Pharmacol. Exp. Ther. |
pmid:27317800
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Clinical pharmacology, efficacy, and safety aspects of sphingosine-1-phosphate receptor modulators. |
2016 |
Expert Opin Drug Metab Toxicol |
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Diabetes Mellitus Is Associated With Reduced High-Density Lipoprotein Sphingosine-1-Phosphate Content and Impaired High-Density Lipoprotein Cardiac Cell Protection. |
2016 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:26966278
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Chawla S et al. |
S1P prophylaxis mitigates acute hypobaric hypoxia-induced molecular, biochemical, and metabolic disturbances: A preclinical report. |
2016 |
IUBMB Life |
pmid:26959531
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Platelet-derived sphingosine-1-phosphate and inflammation: from basic mechanisms to clinical implications. |
2016 |
Platelets |
pmid:26950429
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Morel S et al. |
Sphingosine-1-phosphate reduces ischaemia-reperfusion injury by phosphorylating the gap junction protein Connexin43. |
2016 |
Cardiovasc. Res. |
pmid:26762268
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Sundaram K et al. |
Loss of neutral ceramidase protects cells from nutrient- and energy -deprivation-induced cell death. |
2016 |
Biochem. J. |
pmid:26747710
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Abu Khweek A et al. |
The Sphingosine-1-Phosphate Lyase (LegS2) Contributes to the Restriction of Legionella pneumophila in Murine Macrophages. |
2016 |
PLoS ONE |
pmid:26741365
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Deniz U et al. |
A systematic methodology for large scale compound screening: A case study on the discovery of novel S1PL inhibitors. |
2016 |
J. Mol. Graph. Model. |
pmid:26724452
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Filipenko I et al. |
Upregulation of the S1P3 receptor in metastatic breast cancer cells increases migration and invasion by induction of PGE2 and EP2/EP4 activation. |
2016 |
Biochim. Biophys. Acta |
pmid:27616330
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