Rieken S et al. |
Lysophospholipids control integrin-dependent adhesion in splenic B cells through G(i) and G(12)/G(13) family G-proteins but not through G(q)/G(11). |
2006 |
J. Biol. Chem. |
pmid:17023430
|
Garg SK et al. |
Does sphingosine 1-phosphate play a protective role in the course of pulmonary tuberculosis? |
2006 |
Clin. Immunol. |
pmid:17049310
|
Mitra P et al. |
Role of ABCC1 in export of sphingosine-1-phosphate from mast cells. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:17050692
|
Yatomi Y |
[Elucidation of the functional roles of lysophospholipid mediators and its application in laboratory medicine]. |
2006 |
Rinsho Byori |
pmid:16913663
|
Leclercq TM and Pitson SM |
Cellular signalling by sphingosine kinase and sphingosine 1-phosphate. |
2006 |
IUBMB Life |
pmid:16916784
|
Kohno M et al. |
Intracellular role for sphingosine kinase 1 in intestinal adenoma cell proliferation. |
2006 |
Mol. Cell. Biol. |
pmid:16980623
|
Theilmeier G et al. |
High-density lipoproteins and their constituent, sphingosine-1-phosphate, directly protect the heart against ischemia/reperfusion injury in vivo via the S1P3 lysophospholipid receptor. |
2006 |
Circulation |
pmid:16982942
|
Kihara A |
[Multifunctional sphingolipid, sphingosine (long-chain base) 1-phosphate: physiological role, metabolism, and intracellular dynamics]. |
2006 |
Seikagaku |
pmid:16986722
|
Murph M et al. |
Of spiders and crabs: the emergence of lysophospholipids and their metabolic pathways as targets for therapy in cancer. |
2006 |
Clin. Cancer Res. |
pmid:17121877
|
Birgbauer E and Chun J |
New developments in the biological functions of lysophospholipids. |
2006 |
Cell. Mol. Life Sci. |
pmid:16988788
|
Ryu J et al. |
Sphingosine 1-phosphate as a regulator of osteoclast differentiation and osteoclast-osteoblast coupling. |
2006 |
EMBO J. |
pmid:17124500
|
Jin YX et al. |
Sphingosine kinase assay system with fluorescent detection in high performance liquid chromatography. |
2006 |
Arch. Pharm. Res. |
pmid:17146975
|
Taha TA et al. |
A house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell death. |
2006 |
Biochim. Biophys. Acta |
pmid:17161984
|
Fisher KE et al. |
Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling. |
2006 |
Mol. Cancer |
pmid:17156449
|
Huwiler A and Pfeilschifter J |
Altering the sphingosine-1-phosphate/ceramide balance: a promising approach for tumor therapy. |
2006 |
Curr. Pharm. Des. |
pmid:17168766
|
Pan S et al. |
A monoselective sphingosine-1-phosphate receptor-1 agonist prevents allograft rejection in a stringent rat heart transplantation model. |
2006 |
Chem. Biol. |
pmid:17114004
|
Lee JF et al. |
Dual roles of tight junction-associated protein, zonula occludens-1, in sphingosine 1-phosphate-mediated endothelial chemotaxis and barrier integrity. |
2006 |
J. Biol. Chem. |
pmid:16891661
|
Zheng DM et al. |
Sphingosine 1-phosphate protects rat liver sinusoidal endothelial cells from ethanol-induced apoptosis: Role of intracellular calcium and nitric oxide. |
2006 |
Hepatology |
pmid:17058266
|
Keller M et al. |
Sphingosine kinase functionally links elevated transmural pressure and increased reactive oxygen species formation in resistance arteries. |
2006 |
FASEB J. |
pmid:16476702
|
Wendler CC and Rivkees SA |
Sphingosine-1-phosphate inhibits cell migration and endothelial to mesenchymal cell transformation during cardiac development. |
2006 |
Dev. Biol. |
pmid:16434032
|
Berdyshev EV et al. |
De novo biosynthesis of dihydrosphingosine-1-phosphate by sphingosine kinase 1 in mammalian cells. |
2006 |
Cell. Signal. |
pmid:16529909
|
Schubert R |
Sphingosine-1-phosphate in the circulatory system: Cause and therapeutic target for vascular dysfunction? |
2006 |
Cardiovasc. Res. |
pmid:16542647
|
Ochi R et al. |
Sphingosine-1-phosphate effects on guinea pig atrial myocytes: Alterations in action potentials and K+ currents. |
2006 |
Cardiovasc. Res. |
pmid:16545787
|
Betito S and Cuvillier O |
Regulation by sphingosine 1-phosphate of Bax and Bad activities during apoptosis in a MEK-dependent manner. |
2006 |
Biochem. Biophys. Res. Commun. |
pmid:16414356
|
Lee JF et al. |
Sphingosine-1-phosphate signaling regulates lamellipodia localization of cortactin complexes in endothelial cells. |
2006 |
Histochem. Cell Biol. |
pmid:16416022
|
Taha TA et al. |
Sphingosine kinase: biochemical and cellular regulation and role in disease. |
2006 |
J. Biochem. Mol. Biol. |
pmid:16584625
|
Malaplate-Armand C et al. |
Soluble oligomers of amyloid-beta peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceramide pathway. |
2006 |
Neurobiol. Dis. |
pmid:16626961
|
Lin CI et al. |
Lysophospholipids increase IL-8 and MCP-1 expressions in human umbilical cord vein endothelial cells through an IL-1-dependent mechanism. |
2006 |
J. Cell. Biochem. |
pmid:16795034
|
Hiraga Y et al. |
Changes in S1P1 and S1P2 expression during embryonal development and primitive endoderm differentiation of F9 cells. |
2006 |
Biochem. Biophys. Res. Commun. |
pmid:16631609
|
French KJ et al. |
Antitumor activity of sphingosine kinase inhibitors. |
2006 |
J. Pharmacol. Exp. Ther. |
pmid:16632640
|
Milstien S and Spiegel S |
Targeting sphingosine-1-phosphate: a novel avenue for cancer therapeutics. |
2006 |
Cancer Cell |
pmid:16530698
|
Visentin B et al. |
Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages. |
2006 |
Cancer Cell |
pmid:16530706
|
Scherer EQ et al. |
Sphingosine-1-phosphate modulates spiral modiolar artery tone: A potential role in vascular-based inner ear pathologies? |
2006 |
Cardiovasc. Res. |
pmid:16533504
|
Rouach N et al. |
S1P inhibits gap junctions in astrocytes: involvement of G and Rho GTPase/ROCK. |
2006 |
Eur. J. Neurosci. |
pmid:16553609
|
Brizuela L et al. |
Sphingosine 1-phosphate: a novel stimulator of aldosterone secretion. |
2006 |
J. Lipid Res. |
pmid:16554657
|
Chatterjee S et al. |
The role of the phospholipid sphingomyelin in heart disease. |
2006 |
Curr Opin Investig Drugs |
pmid:16555682
|
Zeidan YH et al. |
Acid ceramidase but not acid sphingomyelinase is required for tumor necrosis factor-{alpha}-induced PGE2 production. |
2006 |
J. Biol. Chem. |
pmid:16803890
|
Dindo D et al. |
Cationic long-chain ceramide LCL-30 induces cell death by mitochondrial targeting in SW403 cells. |
2006 |
Mol. Cancer Ther. |
pmid:16818511
|
Durand CA et al. |
The Rap GTPases mediate CXCL13- and sphingosine1-phosphate-induced chemotaxis, adhesion, and Pyk2 tyrosine phosphorylation in B lymphocytes. |
2006 |
Eur. J. Immunol. |
pmid:16821235
|
Giussani P et al. |
Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramide. |
2006 |
Mol. Cell. Biol. |
pmid:16782891
|
Sanna MG et al. |
Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo. |
2006 |
Nat. Chem. Biol. |
pmid:16829954
|
Veracini L et al. |
Two distinct pools of Src family tyrosine kinases regulate PDGF-induced DNA synthesis and actin dorsal ruffles. |
2006 |
J. Cell. Sci. |
pmid:16787943
|
Laychock SG et al. |
Sphingosine 1-phosphate affects cytokine-induced apoptosis in rat pancreatic islet beta-cells. |
2006 |
Endocrinology |
pmid:16794003
|
Oz-Arslan D et al. |
IL-6 and IL-8 release is mediated via multiple signaling pathways after stimulating dendritic cells with lysophospholipids. |
2006 |
J. Leukoc. Biol. |
pmid:16769764
|
Garbers DL et al. |
Membrane guanylyl cyclase receptors: an update. |
2006 |
Trends Endocrinol. Metab. |
pmid:16815030
|
Jiang X and Han X |
Characterization and direct quantitation of sphingoid base-1-phosphates from lipid extracts: a shotgun lipidomics approach. |
2006 |
J. Lipid Res. |
pmid:16682747
|
Zhang YH et al. |
Sphingosine-1-phosphate via activation of a G-protein-coupled receptor(s) enhances the excitability of rat sensory neurons. |
2006 |
J. Neurophysiol. |
pmid:16723416
|
Zhang YH et al. |
Intracellular sphingosine 1-phosphate mediates the increased excitability produced by nerve growth factor in rat sensory neurons. |
2006 |
J. Physiol. (Lond.) |
pmid:16740613
|
Hu W et al. |
Lentiviral siRNA silencing of sphingosine-1-phosphate receptors S1P1 and S1P2 in smooth muscle. |
2006 |
Biochem. Biophys. Res. Commun. |
pmid:16574065
|
Zhi L et al. |
Sphingosine kinase 1 regulates pro-inflammatory responses triggered by TNFalpha in primary human monocytes. |
2006 |
J. Cell. Physiol. |
pmid:16575915
|
Wacker BK et al. |
Delivery of sphingosine 1-phosphate from poly(ethylene glycol) hydrogels. |
2006 |
Biomacromolecules |
pmid:16602758
|
Hemmings DG et al. |
Sphingosine-1-phosphate acts via rho-associated kinase and nitric oxide to regulate human placental vascular tone. |
2006 |
Biol. Reprod. |
pmid:16162874
|
Yamashita H et al. |
Sphingosine 1-phosphate receptor expression profile in human gastric cancer cells: differential regulation on the migration and proliferation. |
2006 |
J. Surg. Res. |
pmid:16183075
|
Sparkman L et al. |
Ceramide decreases surfactant protein B gene expression via downregulation of TTF-1 DNA binding activity. |
2006 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:16183668
|
Ozbay T et al. |
Cyclic adenosine 5'-monophosphate-dependent sphingosine-1-phosphate biosynthesis induces human CYP17 gene transcription by activating cleavage of sterol regulatory element binding protein 1. |
2006 |
Endocrinology |
pmid:16306078
|
Kobayashi N et al. |
Sphingosine 1-phosphate is released from the cytosol of rat platelets in a carrier-mediated manner. |
2006 |
J. Lipid Res. |
pmid:16371645
|
Olivera A et al. |
IgE-dependent activation of sphingosine kinases 1 and 2 and secretion of sphingosine 1-phosphate requires Fyn kinase and contributes to mast cell responses. |
2006 |
J. Biol. Chem. |
pmid:16316995
|
Kawamori T et al. |
Sphingosine kinase 1 is up-regulated in colon carcinogenesis. |
2006 |
FASEB J. |
pmid:16319132
|
Roviezzo F et al. |
Essential requirement for sphingosine kinase activity in eNOS-dependent NO release and vasorelaxation. |
2006 |
FASEB J. |
pmid:16322129
|
Der P et al. |
Role of lipid rafts in ceramide and nitric oxide signaling in the ischemic and preconditioned hearts. |
2006 |
J. Mol. Cell. Cardiol. |
pmid:16337960
|
Park KS et al. |
Lysophosphatidylserine stimulates L2071 mouse fibroblast chemotactic migration via a process involving pertussis toxin-sensitive trimeric G-proteins. |
2006 |
Mol. Pharmacol. |
pmid:16368894
|
Gonzalez E et al. |
Rac1 modulates sphingosine 1-phosphate-mediated activation of phosphoinositide 3-kinase/Akt signaling pathways in vascular endothelial cells. |
2006 |
J. Biol. Chem. |
pmid:16339142
|
Gardell SE et al. |
Emerging medicinal roles for lysophospholipid signaling. |
2006 |
Trends Mol Med |
pmid:16406843
|
Kim MY et al. |
Sphingosine-1-phosphate activates BKCa channels independently of G protein-coupled receptor in human endothelial cells. |
2006 |
Am. J. Physiol., Cell Physiol. |
pmid:16267108
|
di Villa Bianca Rd et al. |
Sphingosine 1-phosphate induces endothelial nitric-oxide synthase activation through phosphorylation in human corpus cavernosum. |
2006 |
J. Pharmacol. Exp. Ther. |
pmid:16234413
|
Bu S et al. |
Dihydrosphingosine 1-phosphate stimulates MMP1 gene expression via activation of ERK1/2-Ets1 pathway in human fibroblasts. |
2006 |
FASEB J. |
pmid:16278291
|
Inniss K and Moore H |
Mediation of apoptosis and proliferation of human embryonic stem cells by sphingosine-1-phosphate. |
2006 |
Stem Cells Dev. |
pmid:17253942
|
Matsuyuki H et al. |
Involvement of sphingosine 1-phosphate (S1P) receptor type 1 and type 4 in migratory response of mouse T cells toward S1P. |
2006 |
Cell. Mol. Immunol. |
pmid:17257496
|
Rahaman M et al. |
Neutrophil sphingosine 1-phosphate and lysophosphatidic acid receptors in pneumonia. |
2006 |
Am. J. Respir. Cell Mol. Biol. |
pmid:16224106
|
Kang JS et al. |
Glabridin suppresses intercellular adhesion molecule-1 expression in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells by blocking sphingosine kinase pathway: implications of Akt, extracellular signal-regulated kinase, and nuclear factor-kappaB/Rel signaling pathways. |
2006 |
Mol. Pharmacol. |
pmid:16354764
|
Schmidt H et al. |
LC-MS/MS-analysis of sphingosine-1-phosphate and related compounds in plasma samples. |
2006 |
Prostaglandins Other Lipid Mediat. |
pmid:17085324
|
Tardieu D et al. |
Effects of fumonisins on liver and kidney sphinganine and the sphinganine to sphingosine ratio during chronic exposure in ducks. |
2006 |
Chem. Biol. Interact. |
pmid:16412405
|
Massberg S and von Andrian UH |
Fingolimod and sphingosine-1-phosphate--modifiers of lymphocyte migration. |
2006 |
N. Engl. J. Med. |
pmid:16971715
|
Jun DJ et al. |
Sphingosine-1-phosphate modulates both lipolysis and leptin production in differentiated rat white adipocytes. |
2006 |
Endocrinology |
pmid:16973728
|
Natarajan J et al. |
Text mining of full-text journal articles combined with gene expression analysis reveals a relationship between sphingosine-1-phosphate and invasiveness of a glioblastoma cell line. |
2006 |
BMC Bioinformatics |
pmid:16901352
|
Young N and Van Brocklyn JR |
Signal transduction of sphingosine-1-phosphate G protein-coupled receptors. |
2006 |
ScientificWorldJournal |
pmid:16906327
|
Whetzel AM et al. |
Sphingosine-1 phosphate prevents monocyte/endothelial interactions in type 1 diabetic NOD mice through activation of the S1P1 receptor. |
2006 |
Circ. Res. |
pmid:16960101
|
El-Shewy HM et al. |
Insulin-like growth factors mediate heterotrimeric G protein-dependent ERK1/2 activation by transactivating sphingosine 1-phosphate receptors. |
2006 |
J. Biol. Chem. |
pmid:16926156
|
Huang WR et al. |
[Impact of rhG-CSF on sphingosine 1-phosphate concentration in blood plasma of donors]. |
2006 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:16928321
|
Meriane M et al. |
Cooperation of matrix metalloproteinases with the RhoA/Rho kinase and mitogen-activated protein kinase kinase-1/extracellular signal-regulated kinase signaling pathways is required for the sphingosine-1-phosphate-induced mobilization of marrow-derived stromal cells. |
2006 |
Stem Cells |
pmid:16931773
|
Bjursell M et al. |
G protein-coupled receptor 12 deficiency results in dyslipidemia and obesity in mice. |
2006 |
Biochem. Biophys. Res. Commun. |
pmid:16887097
|
Donati C and Bruni P |
Sphingosine 1-phosphate regulates cytoskeleton dynamics: implications in its biological response. |
2006 |
Biochim. Biophys. Acta |
pmid:16890187
|
Thompson B et al. |
Protein kinase Calpha and sphingosine 1-phosphate-dependent signaling in endothelial cell. |
2006 |
Prostaglandins Other Lipid Mediat. |
pmid:16846783
|
Long JS et al. |
The functional PDGFbeta receptor-S1P1 receptor signaling complex is involved in regulating migration of mouse embryonic fibroblasts in response to platelet derived growth factor. |
2006 |
Prostaglandins Other Lipid Mediat. |
pmid:16846788
|
Nagata Y et al. |
Entry of muscle satellite cells into the cell cycle requires sphingolipid signaling. |
2006 |
J. Cell Biol. |
pmid:16847102
|
Xu R et al. |
Golgi alkaline ceramidase regulates cell proliferation and survival by controlling levels of sphingosine and S1P. |
2006 |
FASEB J. |
pmid:16940153
|
Schultz C |
Lipid-induced phenotypes. |
2006 |
Nat. Chem. Biol. |
pmid:16850012
|
Brinkmann V and Baumruker T |
Pulmonary and vascular pharmacology of sphingosine 1-phosphate. |
2006 |
Curr Opin Pharmacol |
pmid:16563863
|
Hemmings DG |
Signal transduction underlying the vascular effects of sphingosine 1-phosphate and sphingosylphosphorylcholine. |
2006 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:16570136
|
Choueiri TK et al. |
Phenoxodiol: isoflavone analog with antineoplastic activity. |
2006 |
Curr Oncol Rep |
pmid:16507219
|
Naetzker S et al. |
Activation of p38 mitogen-activated protein kinase and partial reactivation of the cell cycle by cis-4-methylsphingosine direct postmitotic neurons towards apoptosis. |
2006 |
Genes Cells |
pmid:16483315
|
Jurisicova A et al. |
Molecular requirements for doxorubicin-mediated death in murine oocytes. |
2006 |
Cell Death Differ. |
pmid:16439991
|
Bassi R et al. |
Sphingosine-1-phosphate is released by cerebellar astrocytes in response to bFGF and induces astrocyte proliferation through Gi-protein-coupled receptors. |
2006 |
Glia |
pmid:16470810
|
Yatomi Y |
Sphingosine 1-phosphate in vascular biology: possible therapeutic strategies to control vascular diseases. |
2006 |
Curr. Pharm. Des. |
pmid:16472149
|
Kurobe H et al. |
CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance. |
2006 |
Immunity |
pmid:16473829
|
Kitano M et al. |
Sphingosine 1-phosphate/sphingosine 1-phosphate receptor 1 signaling in rheumatoid synovium: regulation of synovial proliferation and inflammatory gene expression. |
2006 |
Arthritis Rheum. |
pmid:16508938
|
Hsieh HL et al. |
Sphingosine-1-phosphate induces COX-2 expression via PI3K/Akt and p42/p44 MAPK pathways in rat vascular smooth muscle cells. |
2006 |
J. Cell. Physiol. |
pmid:16508949
|
Becciolini L et al. |
Sphingosine 1-phosphate inhibits cell migration in C2C12 myoblasts. |
2006 |
Biochim. Biophys. Acta |
pmid:16510307
|
Song HJ et al. |
Sphingosine 1-phosphate-induced signal transduction in cat esophagus smooth muscle cells. |
2006 |
Mol. Cells |
pmid:16511346
|
Takai S et al. |
Phosphatidylinositol 3-kinase/Akt plays a role in sphingosine 1-phosphate-stimulated HSP27 induction in osteoblasts. |
2006 |
J. Cell. Biochem. |
pmid:16514645
|