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Proc. Natl. Acad. Sci. U.S.A. |
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2017 |
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Fas/S1P crosstalk via NF-κB activation in osteoclasts controls subchondral bone remodeling in murine TMJ arthritis. |
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β-Blockade Prevents Post-Ischemic Myocardial Decompensation Via βAR-Dependent Protective Sphingosine-1 Phosphate Signaling. |
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Modulation of sphingosine-1-phosphate in inflammatory bowel disease. |
2017 |
Autoimmun Rev |
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Sphingosine 1-phosphate receptor 1 regulates the directional migration of lymphatic endothelial cells in response to fluid shear stress. |
2016 |
J R Soc Interface |
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Serum-Sphingosine-1-Phosphate Concentrations Are Inversely Associated with Atherosclerotic Diseases in Humans. |
2016 |
PLoS ONE |
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To fingolimod and beyond: The rich pipeline of drug candidates that target S1P signaling. |
2016 |
Pharmacol. Res. |
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Sphingosine 1-Phosphate Activation of EGFR As a Novel Target for Meningitic Escherichia coli Penetration of the Blood-Brain Barrier. |
2016 |
PLoS Pathog. |
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The Involvment of Hematopoietic-Specific PLC -β2 in Homing and Engraftment of Hematopoietic Stem/Progenitor Cells. |
2016 |
Stem Cell Rev |
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SPHK1/sphingosine kinase 1-mediated autophagy differs between neurons and SH-SY5Y neuroblastoma cells. |
2016 |
Autophagy |
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The roles of bile acids and sphingosine-1-phosphate signaling in the hepatobiliary diseases. |
2016 |
J. Lipid Res. |
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CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice. |
2016 |
Immunity |
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Berberine Preconditioning Protects Neurons Against Ischemia via Sphingosine-1-Phosphate and Hypoxia-Inducible Factor-1[Formula: see text]. |
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Downregulation of Heme Oxygenase 1 (HO-1) Activity in Hematopoietic Cells Enhances Their Engraftment After Transplantation. |
2016 |
Cell Transplant |
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ApoA-I induces S1P release from endothelial cells through ABCA1 and SR-BI in a positive feedback manner. |
2016 |
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A novel approach for measuring sphingosine-1-phosphate and lysophosphatidic acid binding to carrier proteins using monoclonal antibodies and the Kinetic Exclusion Assay. |
2016 |
J. Lipid Res. |
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Structural Insight into Substrate Selection and Catalysis of Lipid Phosphate Phosphatase PgpB in the Cell Membrane. |
2016 |
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The SphKs/S1P/S1PR1 axis in immunity and cancer: more ore to be mined. |
2016 |
World J Surg Oncol |
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2016 |
Transfus Med |
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Sphingosine-1-Phosphate Signaling in Endothelial Disorders. |
2016 |
Curr Atheroscler Rep |
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Melatonin inhibits the sphingosine kinase 1/sphingosine-1-phosphate signaling pathway in rabbits with fulminant hepatitis of viral origin. |
2016 |
J. Pineal Res. |
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Sphingosine-1-Phosphate (S1P) Impacts Presynaptic Functions by Regulating Synapsin I Localization in the Presynaptic Compartment. |
2016 |
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FOXF1 maintains endothelial barrier function and prevents edema after lung injury. |
2016 |
Sci Signal |
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Sphingosine 1-phosphate elicits RhoA-dependent proliferation and MRTF-A mediated gene induction in CPCs. |
2016 |
Cell. Signal. |
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Transcriptional modulation of SLC26A3 (DRA) by sphingosine-1-phosphate. |
2016 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
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Exploration of the Sphingolipid Metabolite, Sphingosine-1-phosphate and Sphingosine, as Novel Biomarkers for Aspirin-exacerbated Respiratory Disease. |
2016 |
Sci Rep |
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Binding Characteristics of Sphingosine-1-Phosphate to ApoM hints to Assisted Release Mechanism via the ApoM Calyx-Opening. |
2016 |
Sci Rep |
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Erythropoeitin Signaling in Macrophages Promotes Dying Cell Clearance and Immune Tolerance. |
2016 |
Immunity |
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Overexpression of SphK1 enhances cell proliferation and invasion in triple-negative breast cancer via the PI3K/AKT signaling pathway. |
2016 |
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The neutral sphingomyelinase-2 is involved in angiogenic signaling triggered by oxidized LDL. |
2016 |
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The Role of Sphingosine-1-Phosphate in Adipogenesis of Graves' Orbitopathy. |
2016 |
Invest. Ophthalmol. Vis. Sci. |
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Sphingosine-1-Phosphate Induces Dose-Dependent Chemotaxis or Fugetaxis of T-ALL Blasts through S1P1 Activation. |
2016 |
PLoS ONE |
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Reinforced Epithelial Barrier Integrity via Matriptase Induction with Sphingosine-1-Phosphate Did Not Result in Disturbances in Physiological Redox Status. |
2016 |
Oxid Med Cell Longev |
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Regulation of human cerebro-microvascular endothelial baso-lateral adhesion and barrier function by S1P through dual involvement of S1P1 and S1P2 receptors. |
2016 |
Sci Rep |
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Deletion of sphingosine kinase 1 ameliorates hepatic steatosis in diet-induced obese mice: Role of PPARγ. |
2016 |
Biochim. Biophys. Acta |
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Sphingosine-1-phosphate and estrogen signaling in breast cancer. |
2016 |
Adv Biol Regul |
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Sphingosine 1-phosphate signaling contributes to cardiac inflammation, dysfunction, and remodeling following myocardial infarction. |
2016 |
Am. J. Physiol. Heart Circ. Physiol. |
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A reflection of the lasting contributions from Dr. Robert Bittman to sterol trafficking, sphingolipid and phospholipid research. |
2016 |
Prog. Lipid Res. |
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Rana A and Sharma S |
Mechanism of sphingosine-1-phosphate induced cardioprotection against I/R injury in diabetic rat heart: Possible involvement of glycogen synthase kinase 3β and mitochondrial permeability transition pore. |
2016 |
Clin. Exp. Pharmacol. Physiol. |
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Metabolomics study on the antitumor effect of marine natural compound flexibilide in HCT-116 colon cancer cell line. |
2016 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
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Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-β autocrine loop. |
2016 |
Oncotarget |
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Interstitial Fluid Sphingosine-1-Phosphate in Murine Mammary Gland and Cancer and Human Breast Tissue and Cancer Determined by Novel Methods. |
2016 |
J Mammary Gland Biol Neoplasia |
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Aberrant expression of the S1P regulating enzymes, SPHK1 and SGPL1, contributes to a migratory phenotype in OSCC mediated through S1PR2. |
2016 |
Sci Rep |
pmid:27160553
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Li N and Zhang F |
Implication of sphingosin-1-phosphate in cardiovascular regulation. |
2016 |
Front Biosci (Landmark Ed) |
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Fingolimod protects against neonatal white matter damage and long-term cognitive deficits caused by hyperoxia. |
2016 |
Brain Behav. Immun. |
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Sphingosine-1-phosphate signaling: unraveling its role as a drug target against infectious diseases. |
2016 |
Drug Discov. Today |
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Sphingosine-1-phosphate Maintains Normal Vascular Permeability by Preserving Endothelial Surface Glycocalyx in Intact Microvessels. |
2016 |
Microcirculation |
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Resveratrol exerts a biphasic effect on apolipoprotein M. |
2016 |
Br. J. Pharmacol. |
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Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate. |
2016 |
J. Hepatol. |
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