Yin GJ et al. |
[Antitumor effect of sphingosine kinase 1 inhibitor in combination with chemotherapy on SGC7901 gastric cancer cells in vitro]. |
2012 |
Zhonghua Zhong Liu Za Zhi |
pmid:22780925
|
Liu SQ et al. |
[Sphingosine kinase 1 enhances the proliferation and invasion of human colon cancer LoVo cells through up-regulating FAK pathway and the expression of ICAM-1 and VCAM-1]. |
2013 |
Zhonghua Zhong Liu Za Zhi |
pmid:24054007
|
Liu SQ et al. |
[Effect of sphingosine kinase 1 on the apoptosis, migration and invasion of colon cancer HT-29 cells and its molecular mechanisms]. |
2011 |
Zhonghua Zhong Liu Za Zhi |
pmid:21575515
|
Yu HM et al. |
[Regulation of sphingosine kinase 1 in the TNF-α-induced expression of MUC5AC in airway epithelial cells]. |
2011 |
Zhonghua Yi Xue Za Zhi |
pmid:21418911
|
Ren J et al. |
Expression of sphingosine kinase gene in the interactions between human gastric carcinoma cell and vascular endothelial cell. |
2002 |
World J. Gastroenterol. |
pmid:12174364
|
Lei YC et al. |
Inhibition of sphingosine kinase 1 ameliorates acute liver failure by reducing high-mobility group box 1 cytoplasmic translocation in liver cells. |
2015 |
World J. Gastroenterol. |
pmid:26676341
|
Zhang Z et al. |
SPHK1 inhibitor suppresses cell proliferation and invasion associated with the inhibition of NF-κB pathway in hepatocellular carcinoma. |
2015 |
Tumour Biol. |
pmid:25537088
|
Ohmori T et al. |
The intracellular action of sphingosine 1-phosphate in GPVI-mediated Ca2+ mobilization in platelets. |
2005 |
Thromb. Res. |
pmid:15733975
|
Okamoto H et al. |
Sphingosine 1-phosphate stimulates G(i)- and Rho-mediated vascular endothelial cell spreading and migration. |
2000 |
Thromb. Res. |
pmid:10942792
|
Igarashi Y |
[Bioregulatory functions of methylsphingosines: in relation to sphingolipid signaling pathway and on approach of introducing sphingolipid-based drugs]. |
1998 |
Tanpakushitsu Kakusan Koso |
pmid:9528354
|
Leitzke AS et al. |
Isoflurane post-treatment ameliorates GMH-induced brain injury in neonatal rats. |
2013 |
Stroke |
pmid:24149004
|
Itagaki K et al. |
Sphingosine kinase inhibition alleviates endothelial permeability induced by thrombin and activated neutrophils. |
2010 |
Shock |
pmid:19851125
|
Hobson JP et al. |
Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility. |
2001 |
Science |
pmid:11230698
|
Kono Y et al. |
Sphingosine kinase 1 regulates mucin production via ERK phosphorylation. |
2010 |
Pulm Pharmacol Ther |
pmid:19835973
|
Leroux ME et al. |
Sphingolipids and the sphingosine kinase inhibitor, SKI II, induce BCL-2-independent apoptosis in human prostatic adenocarcinoma cells. |
2007 |
Prostate |
pmid:17879964
|
Kim HL et al. |
Characterization of N,N,-dimethyl-D-erythro-sphingosine-induced apoptosis and signaling in U937 cells: independence of sphingosine kinase inhibition. |
2008 |
Prostaglandins Other Lipid Mediat. |
pmid:18316219
|
Kim HL et al. |
Differential signaling of sphingosine derivatives in U937 human monocytes depends on the degree of N-methylation. |
2008 |
Prostaglandins Other Lipid Mediat. |
pmid:18467142
|
Xia P et al. |
Tumor necrosis factor-alpha induces adhesion molecule expression through the sphingosine kinase pathway. |
1998 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:9826677
|
Kaneider NC et al. |
Leukocyte motility in response to neuropeptides is heparan sulfate proteoglycan dependent. |
2003 |
Peptides |
pmid:12895655
|
Chen YJ et al. |
Inflammation triggers production of dimethylsphingosine from oligodendrocytes. |
2014 |
Neuroscience |
pmid:25151189
|
Hanafusa N et al. |
Sphingosine 1-phosphate stimulates rat mesangial cell proliferation from outside the cells. |
2002 |
Nephrol. Dial. Transplant. |
pmid:11917049
|
Trifilieff A et al. |
Role of sphingosine-1-phosphate (S1P) and the S1P(2) receptor in allergen-induced, mast cell-dependent contraction of rat lung parenchymal strips. |
2009 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:19636535
|
Kim HJ et al. |
Suppression of osteoclastogenesis by N,N-dimethyl-D-erythro-sphingosine: a sphingosine kinase inhibition-independent action. |
2007 |
Mol. Pharmacol. |
pmid:17504945
|
Lan T et al. |
Sphingosine kinase-1 pathway mediates high glucose-induced fibronectin expression in glomerular mesangial cells. |
2011 |
Mol. Endocrinol. |
pmid:21998146
|
Lee YK et al. |
Multiple actions of dimethylsphingosine in 1321N1 astrocytes. |
2007 |
Mol. Cells |
pmid:17464206
|
Nam JH et al. |
Sphingosine and FTY720 modulate pacemaking activity in interstitial cells of Cajal from mouse small intestine. |
2013 |
Mol. Cells |
pmid:23912597
|
Wang H et al. |
N-(4-Hydroxyphenyl)retinamide increases dihydroceramide and synergizes with dimethylsphingosine to enhance cancer cell killing. |
2008 |
Mol. Cancer Ther. |
pmid:18790777
|
Van IJzendoorn SC et al. |
Polarized membrane traffic and cell polarity development is dependent on dihydroceramide synthase-regulated sphinganine turnover. |
2004 |
Mol. Biol. Cell |
pmid:15229289
|
Kanno T and Nishizaki T |
Endogenous sphingosine 1-phosphate regulates spontaneous glutamate release from mossy fiber terminals via S1P(3) receptors. |
2011 |
Life Sci. |
pmid:21683714
|
Pallis M |
Sphingosine kinase inhibitors in the apoptosis of leukaemia cells. |
2002 |
Leuk. Res. |
pmid:11839389
|
Jendiroba DB et al. |
Effective cytotoxicity against human leukemias and chemotherapy-resistant leukemia cell lines by N-N-dimethylsphingosine. |
2002 |
Leuk. Res. |
pmid:11792420
|
Chan L |
Harnessing regulatory T cells for therapeutic purposes. |
2012 |
Kidney Int. |
pmid:22543901
|
Lai LW et al. |
Pharmacologic recruitment of regulatory T cells as a therapy for ischemic acute kidney injury. |
2012 |
Kidney Int. |
pmid:22189844
|
Zhang YH et al. |
Brain-derived neurotrophic factor enhances the excitability of rat sensory neurons through activation of the p75 neurotrophin receptor and the sphingomyelin pathway. |
2008 |
J. Physiol. (Lond.) |
pmid:18450779
|
Zhang YH et al. |
Intracellular sphingosine 1-phosphate mediates the increased excitability produced by nerve growth factor in rat sensory neurons. |
2006 |
J. Physiol. (Lond.) |
pmid:16740613
|
Jo JY et al. |
N,N-Dimethyl-D-erythro-sphingosine inhibits store-operated Ca2+ entry in U937 monocytes. |
2008 |
J. Pharmacol. Sci. |
pmid:18635921
|
Lee EH et al. |
Dimethylsphingosine regulates intracellular pH and Ca(2+) in human monocytes. |
2006 |
J. Pharmacol. Sci. |
pmid:16575153
|
Saini HS et al. |
Novel role of sphingosine kinase 1 as a mediator of neurotrophin-3 action in oligodendrocyte progenitors. |
2005 |
J. Neurochem. |
pmid:16313513
|
Edsall LC et al. |
Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells. |
2001 |
J. Neurochem. |
pmid:11238741
|
Asle-Rousta M et al. |
Prominence of central sphingosine-1-phosphate receptor-1 in attenuating aβ-induced injury by fingolimod. |
2014 |
J. Mol. Neurosci. |
pmid:25239520
|
Karliner JS et al. |
The lysophospholipids sphingosine-1-phosphate and lysophosphatidic acid enhance survival during hypoxia in neonatal rat cardiac myocytes. |
2001 |
J. Mol. Cell. Cardiol. |
pmid:11549349
|
Wong L et al. |
Synthesis and evaluation of sphingosine analogues as inhibitors of sphingosine kinases. |
2009 |
J. Med. Chem. |
pmid:19469544
|
Sun D and Hurley LH |
The importance of negative superhelicity in inducing the formation of G-quadruplex and i-motif structures in the c-Myc promoter: implications for drug targeting and control of gene expression. |
2009 |
J. Med. Chem. |
pmid:19385599
|
Walev I et al. |
Streptolysin O-permeabilized granulocytes shed L-selectin concomitantly with ceramide generation via neutral sphingomyelinase. |
2000 |
J. Leukoc. Biol. |
pmid:11129654
|
Manggau M et al. |
1Alpha,25-dihydroxyvitamin D3 protects human keratinocytes from apoptosis by the formation of sphingosine-1-phosphate. |
2001 |
J. Invest. Dermatol. |
pmid:11710939
|
MacKinnon AC et al. |
Sphingosine kinase: a point of convergence in the action of diverse neutrophil priming agents. |
2002 |
J. Immunol. |
pmid:12444147
|
Osawa Y et al. |
TNF-alpha-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes. |
2001 |
J. Immunol. |
pmid:11418646
|
Lai WQ et al. |
The role of sphingosine kinase in a murine model of allergic asthma. |
2008 |
J. Immunol. |
pmid:18322246
|
Lai WQ et al. |
Anti-inflammatory effects of sphingosine kinase modulation in inflammatory arthritis. |
2008 |
J. Immunol. |
pmid:19017993
|
Chuang FY et al. |
Convergence of Fc gamma receptor IIA and Fc gamma receptor IIIB signaling pathways in human neutrophils. |
2000 |
J. Immunol. |
pmid:10605030
|