Kim YK et al. |
Differential regulation of protein tyrosine kinase on free radical production, granule enzyme release, and cytokine synthesis by activated murine peritoneal macrophages. |
2001 |
Biochem. Pharmacol. |
pmid:11137713
|
Edsall LC et al. |
Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells. |
2001 |
J. Neurochem. |
pmid:11238741
|
Hollander MC et al. |
Activation of Gadd34 by diverse apoptotic signals and suppression of its growth inhibitory effects by apoptotic inhibitors. |
2001 |
Int. J. Cancer |
pmid:11241327
|
MacKinnon AC et al. |
Sphingosine kinase: a point of convergence in the action of diverse neutrophil priming agents. |
2002 |
J. Immunol. |
pmid:12444147
|
Hanafusa N et al. |
Sphingosine 1-phosphate stimulates rat mesangial cell proliferation from outside the cells. |
2002 |
Nephrol. Dial. Transplant. |
pmid:11917049
|
McCaig C et al. |
Signalling pathways involved in the direct effects of IGFBP-5 on breast epithelial cell attachment and survival. |
2002 |
J. Cell. Biochem. |
pmid:11835403
|
Pallis M |
Sphingosine kinase inhibitors in the apoptosis of leukaemia cells. |
2002 |
Leuk. Res. |
pmid:11839389
|
Jendiroba DB et al. |
Effective cytotoxicity against human leukemias and chemotherapy-resistant leukemia cell lines by N-N-dimethylsphingosine. |
2002 |
Leuk. Res. |
pmid:11792420
|
Ren J et al. |
Expression of sphingosine kinase gene in the interactions between human gastric carcinoma cell and vascular endothelial cell. |
2002 |
World J. Gastroenterol. |
pmid:12174364
|
Xu CB et al. |
D-erythro-N,N-dimethylsphingosine inhibits bFGF-induced proliferation of cerebral, aortic and coronary smooth muscle cells. |
2002 |
Atherosclerosis |
pmid:12204793
|
Alfonso A et al. |
Dimethylsphingosine increases cytosolic calcium and intracellular pH in human T lymphocytes. |
2003 |
Biochem. Pharmacol. |
pmid:12527340
|
Seko A et al. |
Beta 1,4-galactosyltransferase (beta 4GalT)-IV is specific for GlcNAc 6-O-sulfate. Beta 4GalT-IV acts on keratan sulfate-related glycans and a precursor glycan of 6-sulfosialyl-Lewis X. |
2003 |
J. Biol. Chem. |
pmid:12511560
|
Kaneider NC et al. |
Leukocyte motility in response to neuropeptides is heparan sulfate proteoglycan dependent. |
2003 |
Peptides |
pmid:12895655
|
Meacci E et al. |
Sphingosine kinase activity is required for sphingosine-mediated phospholipase D activation in C2C12 myoblasts. |
2004 |
Biochem. J. |
pmid:15109308
|
Park HW et al. |
Enhancement of radiosensitivity by combined ceramide and dimethylsphingosine treatment in lung cancer cells. |
2004 |
Exp. Mol. Med. |
pmid:15557813
|
Jin ZQ et al. |
Sphingosine kinase activation mediates ischemic preconditioning in murine heart. |
2004 |
Circulation |
pmid:15451787
|
Worgall TS et al. |
Ceramide synthesis correlates with the posttranscriptional regulation of the sterol-regulatory element-binding protein. |
2004 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:15132973
|
Welsch CA et al. |
Genetic, biochemical, and transcriptional responses of Saccharomyces cerevisiae to the novel immunomodulator FTY720 largely mimic those of the natural sphingolipid phytosphingosine. |
2004 |
J. Biol. Chem. |
pmid:15190065
|
Kaneider NC et al. |
The immune modulator FTY720 targets sphingosine-kinase-dependent migration of human monocytes in response to amyloid beta-protein and its precursor. |
2004 |
FASEB J. |
pmid:15208267
|
Van IJzendoorn SC et al. |
Polarized membrane traffic and cell polarity development is dependent on dihydroceramide synthase-regulated sphinganine turnover. |
2004 |
Mol. Biol. Cell |
pmid:15229289
|
Roth Z and Hansen PJ |
Sphingosine 1-phosphate protects bovine oocytes from heat shock during maturation. |
2004 |
Biol. Reprod. |
pmid:15317688
|
Min J et al. |
Overexpression of sphingosine-1-phosphate lyase or inhibition of sphingosine kinase in Dictyostelium discoideum results in a selective increase in sensitivity to platinum-based chemotherapy drugs. |
2004 |
Eukaryotic Cell |
pmid:15190000
|
Ibrahim FB et al. |
Anaphylatoxin signaling in human neutrophils. A key role for sphingosine kinase. |
2004 |
J. Biol. Chem. |
pmid:15302883
|
Kaneider NC et al. |
Heparan sulfate proteoglycans are involved in opiate receptor-mediated cell migration. |
2004 |
Biochemistry |
pmid:14705951
|
Duan HF et al. |
Sphingosine kinase activation regulates hepatocyte growth factor induced migration of endothelial cells. |
2004 |
Exp. Cell Res. |
pmid:15265705
|
Min J et al. |
Sphingosine kinase regulates the sensitivity of Dictyostelium discoideum cells to the anticancer drug cisplatin. |
2005 |
Eukaryotic Cell |
pmid:15643073
|
Billich A et al. |
Basal and induced sphingosine kinase 1 activity in A549 carcinoma cells: function in cell survival and IL-1beta and TNF-alpha induced production of inflammatory mediators. |
2005 |
Cell. Signal. |
pmid:16038795
|
Saini HS et al. |
Novel role of sphingosine kinase 1 as a mediator of neurotrophin-3 action in oligodendrocyte progenitors. |
2005 |
J. Neurochem. |
pmid:16313513
|
Ohmori T et al. |
The intracellular action of sphingosine 1-phosphate in GPVI-mediated Ca2+ mobilization in platelets. |
2005 |
Thromb. Res. |
pmid:15733975
|
Jin YX et al. |
Sphingosine kinase assay system with fluorescent detection in high performance liquid chromatography. |
2006 |
Arch. Pharm. Res. |
pmid:17146975
|
Chang YJ et al. |
Structure-activity relationships of dimethylsphingosine (DMS) derivatives and their effects on intracellular pH and Ca2+ in the U937 monocyte cell line. |
2006 |
Arch. Pharm. Res. |
pmid:16964761
|
Jin ZQ and Karliner JS |
Low dose N, N-dimethylsphingosine is cardioprotective and activates cytosolic sphingosine kinase by a PKCepsilon dependent mechanism. |
2006 |
Cardiovasc. Res. |
pmid:16831409
|
Zhang YH et al. |
Intracellular sphingosine 1-phosphate mediates the increased excitability produced by nerve growth factor in rat sensory neurons. |
2006 |
J. Physiol. (Lond.) |
pmid:16740613
|
Lee YK et al. |
Characterization of Ca2+ influx induced by dimethylphytosphingosine and lysophosphatidylcholine in U937 monocytes. |
2006 |
Biochem. Biophys. Res. Commun. |
pmid:16904073
|
Lee EH et al. |
Dimethylsphingosine regulates intracellular pH and Ca(2+) in human monocytes. |
2006 |
J. Pharmacol. Sci. |
pmid:16575153
|
Maines LW et al. |
Pharmacologic manipulation of sphingosine kinase in retinal endothelial cells: implications for angiogenic ocular diseases. |
2006 |
Invest. Ophthalmol. Vis. Sci. |
pmid:17065523
|
Vessey DA et al. |
Dimethylsphingosine and FTY720 inhibit the SK1 form but activate the SK2 form of sphingosine kinase from rat heart. |
2007 |
J. Biochem. Mol. Toxicol. |
pmid:17912702
|
Kim HJ et al. |
Suppression of osteoclastogenesis by N,N-dimethyl-D-erythro-sphingosine: a sphingosine kinase inhibition-independent action. |
2007 |
Mol. Pharmacol. |
pmid:17504945
|
Lee YK et al. |
Multiple actions of dimethylsphingosine in 1321N1 astrocytes. |
2007 |
Mol. Cells |
pmid:17464206
|
Leroux ME et al. |
Sphingolipids and the sphingosine kinase inhibitor, SKI II, induce BCL-2-independent apoptosis in human prostatic adenocarcinoma cells. |
2007 |
Prostate |
pmid:17879964
|
Chandru H and Boggaram V |
The role of sphingosine 1-phosphate in the TNF-alpha induction of IL-8 gene expression in lung epithelial cells. |
2007 |
Gene |
pmid:17306937
|
Coatrieux C et al. |
MAO-A-induced mitogenic signaling is mediated by reactive oxygen species, MMP-2, and the sphingolipid pathway. |
2007 |
Free Radic. Biol. Med. |
pmid:17561096
|
Ghosh SC et al. |
N,N-dimethylsphingosine-coumarin: synthesis, chemical characterization, and biological evaluation. |
2007 May-Jun |
Bioconjug. Chem. |
pmid:17432826
|
Xiong TC et al. |
Sphingolipid metabolites selectively elicit increases in nuclear calcium concentration in cell suspension cultures and in isolated nuclei of tobacco. |
2008 |
Cell Calcium |
pmid:17570488
|
Lai WQ et al. |
The role of sphingosine kinase in a murine model of allergic asthma. |
2008 |
J. Immunol. |
pmid:18322246
|
Jin YX et al. |
A sphingosine kinase activity assay using direct infusion electrospray ionization tandem mass spectrometry. |
2008 |
Anal. Biochem. |
pmid:18541132
|
Nishiuma T et al. |
Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model. |
2008 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:18359884
|
Lai WQ et al. |
Anti-inflammatory effects of sphingosine kinase modulation in inflammatory arthritis. |
2008 |
J. Immunol. |
pmid:19017993
|
Zanin M et al. |
Trophic action of sphingosine 1-phosphate in denervated rat soleus muscle. |
2008 |
Am. J. Physiol., Cell Physiol. |
pmid:17942639
|
Gude DR et al. |
Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a "come-and-get-me" signal. |
2008 |
FASEB J. |
pmid:18362204
|