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Development of an Alamar Blue viability assay in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427. |
2009 |
Am. J. Trop. Med. Hyg. |
pmid:19815884
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Smith JJ et al. |
Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo. |
2009 |
BMC Syst Biol |
pmid:19284563
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Wang H et al. |
N-(4-Hydroxyphenyl)retinamide increases dihydroceramide and synergizes with dimethylsphingosine to enhance cancer cell killing. |
2008 |
Mol. Cancer Ther. |
pmid:18790777
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Xiong TC et al. |
Sphingolipid metabolites selectively elicit increases in nuclear calcium concentration in cell suspension cultures and in isolated nuclei of tobacco. |
2008 |
Cell Calcium |
pmid:17570488
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Lai WQ et al. |
The role of sphingosine kinase in a murine model of allergic asthma. |
2008 |
J. Immunol. |
pmid:18322246
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Kim HL et al. |
Characterization of N,N,-dimethyl-D-erythro-sphingosine-induced apoptosis and signaling in U937 cells: independence of sphingosine kinase inhibition. |
2008 |
Prostaglandins Other Lipid Mediat. |
pmid:18316219
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Jin YX et al. |
A sphingosine kinase activity assay using direct infusion electrospray ionization tandem mass spectrometry. |
2008 |
Anal. Biochem. |
pmid:18541132
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Zhang YH et al. |
Brain-derived neurotrophic factor enhances the excitability of rat sensory neurons through activation of the p75 neurotrophin receptor and the sphingomyelin pathway. |
2008 |
J. Physiol. (Lond.) |
pmid:18450779
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Kim HL et al. |
Differential signaling of sphingosine derivatives in U937 human monocytes depends on the degree of N-methylation. |
2008 |
Prostaglandins Other Lipid Mediat. |
pmid:18467142
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Jo JY et al. |
N,N-Dimethyl-D-erythro-sphingosine inhibits store-operated Ca2+ entry in U937 monocytes. |
2008 |
J. Pharmacol. Sci. |
pmid:18635921
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Nagaoka Y et al. |
Effects of phosphorylation of immunomodulatory agent FTY720 (fingolimod) on antiproliferative activity against breast and colon cancer cells. |
2008 |
Biol. Pharm. Bull. |
pmid:18520051
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Nishiuma T et al. |
Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model. |
2008 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:18359884
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Lai WQ et al. |
Anti-inflammatory effects of sphingosine kinase modulation in inflammatory arthritis. |
2008 |
J. Immunol. |
pmid:19017993
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Zanin M et al. |
Trophic action of sphingosine 1-phosphate in denervated rat soleus muscle. |
2008 |
Am. J. Physiol., Cell Physiol. |
pmid:17942639
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Kim HL and Im DS |
N, N-dimethyl-D-erythro-sphingosine increases intracellular Ca2+ concentration via Na+-Ca2+-exchanger in HCT116 human colon cancer cells. |
2008 |
Arch. Pharm. Res. |
pmid:18277608
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Gude DR et al. |
Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a "come-and-get-me" signal. |
2008 |
FASEB J. |
pmid:18362204
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N,N-dimethylsphingosine-coumarin: synthesis, chemical characterization, and biological evaluation. |
2007 May-Jun |
Bioconjug. Chem. |
pmid:17432826
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Vessey DA et al. |
Dimethylsphingosine and FTY720 inhibit the SK1 form but activate the SK2 form of sphingosine kinase from rat heart. |
2007 |
J. Biochem. Mol. Toxicol. |
pmid:17912702
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Kim HJ et al. |
Suppression of osteoclastogenesis by N,N-dimethyl-D-erythro-sphingosine: a sphingosine kinase inhibition-independent action. |
2007 |
Mol. Pharmacol. |
pmid:17504945
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Leroux ME et al. |
Sphingolipids and the sphingosine kinase inhibitor, SKI II, induce BCL-2-independent apoptosis in human prostatic adenocarcinoma cells. |
2007 |
Prostate |
pmid:17879964
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