fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Adenocarcinoma D000230 166 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Inflammation D007249 119 associated lipids
Glioma D005910 112 associated lipids
Weight Gain D015430 101 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

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Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
De Angelis I et al. Absorption of fumonisin B1 and aminopentol on an in vitro model of intestinal epithelium; the role of P-glycoprotein. 2005 Toxicon pmid:15683866
Ficheux AS et al. Co-exposure of Fusarium mycotoxins: in vitro myelotoxicity assessment on human hematopoietic progenitors. 2012 Toxicon pmid:22921581
Caloni F et al. Evaluation of Fumonisin B(1) and its metabolites absorption and toxicity on intestinal cells line Caco-2. 2002 Toxicon pmid:12165322
Sauviat MP et al. Fumonisin, a toxin from the fungus Fusarium moniliforme sheld, blocks both the calcium current and the mechanical activity in frog atrial muscle. 1991 Toxicon pmid:1658988
Lallès JP et al. Consumption of fumonisin B1 for 9 days induces stress proteins along the gastrointestinal tract of pigs. 2010 Feb-Mar Toxicon pmid:19647010
Dambolena JS et al. Inhibitory effect of cyclic terpenes (limonene, menthol, menthone and thymol) on Fusarium verticillioides MRC 826 growth and fumonisin B1 biosynthesis. 2008 Toxicon pmid:18037463
Sheng Y et al. Development of a sensitive enzyme-linked immunosorbent assay for the detection of fumonisin B₁ in maize. 2012 Toxicon pmid:22960014
Shephard GS et al. Distribution and excretion of a single dose of the mycotoxin fumonisin B1 in a non-human primate. 1994 Toxicon pmid:7940579
Shephard GS et al. Disruption of sphingolipid metabolism in non-human primates consuming diets of fumonisin-containing Fusarium moniliforme culture material. 1996 Toxicon pmid:8783447
Albonico M et al. Toxicological effects of fumonisin B1 alone and in combination with other fusariotoxins on bovine granulosa cells. 2016 Toxicon pmid:27108238
Ling S et al. Preparation and identification of monoclonal antibody against fumonisin B(1) and development of detection by Ic-ELISA. 2014 Toxicon pmid:24378835
Sun LH et al. Individual and combined cytotoxic effects of aflatoxin B1, zearalenone, deoxynivalenol and fumonisin B1 on BRL 3A rat liver cells. 2015 Toxicon pmid:25549941
Abbas HK and Riley RT The presence and phytotoxicity of fumonisins and AAL-toxin in Alternaria alternata. 1996 Toxicon pmid:8835341
Kouadio JH et al. Effects of combinations of Fusarium mycotoxins on the inhibition of macromolecular synthesis, malondialdehyde levels, DNA methylation and fragmentation, and viability in Caco-2 cells. 2007 Toxicon pmid:17109910
van der Westhuizen L et al. The effect of repeated gavage doses of fumonisin B1 on the sphinganine and sphingosine levels in vervet monkeys. 2001 Toxicon pmid:11223085
Abbas HK et al. Biological activities of fumonisins, mycotoxins from Fusarium moniliforme, in jimsonweed (Datura stramonium L.) and mammalian cell cultures. 1993 Toxicon pmid:8470138
Ling S et al. Rapid detection of fumonisin B1 using a colloidal gold immunoassay strip test in corn samples. 2015 Toxicon pmid:26525659
Lock EA et al. Caspase-dependent and -independent induction of phosphatidylserine externalization during apoptosis in human renal carcinoma Cak(1)-1 and A-498 cells. 2007 Toxicology pmid:17097791
Voss KA et al. The role of tumor necrosis factor alpha and the peroxisome proliferator-activated receptor alpha in modulating the effects of fumonisin in mouse liver. 2006 Toxicology pmid:16574297
Abel S and Gelderblom WC Oxidative damage and fumonisin B1-induced toxicity in primary rat hepatocytes and rat liver in vivo. 1998 Toxicology pmid:9928627