| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Brain Diseases | D001927 | 27 associated lipids |
| Carcinoma | D002277 | 18 associated lipids |
| Cardiovascular Diseases | D002318 | 24 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Choline Deficiency | D002796 | 16 associated lipids |
| Cleft Palate | D002972 | 9 associated lipids |
fumonisin b1
fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
Cross Reference
Introduction
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with fumonisin b1?
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with fumonisin b1
PubChem Associated disorders and diseases
What pathways are associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with fumonisin b1?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with fumonisin b1?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with fumonisin b1?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with fumonisin b1?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with fumonisin b1?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with fumonisin b1
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chalfant CE et al. | FAS activation induces dephosphorylation of SR proteins; dependence on the de novo generation of ceramide and activation of protein phosphatase 1. | 2001 | J. Biol. Chem. | pmid:11502750 |
| Lemke SL et al. | Deamination of fumonisin B(1) and biological assessment of reaction product toxicity. | 2001 | Chem. Res. Toxicol. | pmid:11170503 |
| Toxicology and carcinogenesis studies of fumonisin B1 (cas no. 116355-83-0) in F344/N rats and B6C3F1 mice (feed studies). | 2001 | Natl Toxicol Program Tech Rep Ser | pmid:11852482 | |
| Shim WB and Woloshuk CP | Regulation of fumonisin B(1) biosynthesis and conidiation in Fusarium verticillioides by a cyclin-like (C-type) gene, FCC1. | 2001 | Appl. Environ. Microbiol. | pmid:11282612 |
| Spotti M et al. | Fumonisin B1 carry-over into milk in the isolated perfused bovine udder. | 2001 | Vet Hum Toxicol | pmid:11308118 |
| Miguet C et al. | Ceramide generation occurring during 7beta-hydroxycholesterol- and 7-ketocholesterol-induced apoptosis is caspase independent and is not required to trigger cell death. | 2001 | Cell Death Differ. | pmid:11313706 |
| De Girolamo A et al. | Effect of processing on fumonisin concentration in corn flakes. | 2001 | J. Food Prot. | pmid:11348004 |
| Chelule PK et al. | Exposure of rural and urban populations in KwaZulu Natal, South Africa, to fumonisin B(1) in maize. | 2001 | Environ. Health Perspect. | pmid:11333186 |
| Proceedings of the International Conference on the Toxicology of Fumonisin. 28-30 June 1999, Arlington, Virginia. | 2001 | Environ. Health Perspect. | pmid:11359690 | |
| Marasas WF | Discovery and occurrence of the fumonisins: a historical perspective. | 2001 | Environ. Health Perspect. | pmid:11359691 |
| ApSimon JW | Structure, synthesis, and biosynthesis of fumonisin B1 and related compounds. | 2001 | Environ. Health Perspect. | pmid:11359692 |
| Haschek WM et al. | Fumonisin toxicosis in swine: an overview of porcine pulmonary edema and current perspectives. | 2001 | Environ. Health Perspect. | pmid:11359693 |
| Voss KA et al. | An overview of rodent toxicities: liver and kidney effects of fumonisins and Fusarium moniliforme. | 2001 | Environ. Health Perspect. | pmid:11359694 |
| Gelderblom WC et al. | Toxicity of culture material of Fusarium verticillioides strain MRC 826 to nonhuman primates. | 2001 | Environ. Health Perspect. | pmid:11359695 |
| Howard PC et al. | Fumonisin b1 carcinogenicity in a two-year feeding study using F344 rats and B6C3F1 mice. | 2001 | Environ. Health Perspect. | pmid:11359696 |
| Merrill AH et al. | Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins. | 2001 | Environ. Health Perspect. | pmid:11359697 |
| Bezombes C et al. | Lysosomal sphingomyelinase is not solicited for apoptosis signaling. | 2001 | FASEB J. | pmid:11156942 |
| Carlson DB et al. | Fumonisin B1 promotes aflatoxin B1 and N-methyl-N'-nitro-nitrosoguanidine-initiated liver tumors in rainbow trout. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11264020 |
| Zhang Y et al. | Identification of differentially expressed genes following treatment of monkey kidney cells with the mycotoxin fumonisin B(1). | 2001 | Food Chem. Toxicol. | pmid:11259850 |
| Maragos CM et al. | Fluorescence polarization as a means for determination of fumonisins in maize. | 2001 | J. Agric. Food Chem. | pmid:11261998 |
| Momany FA and Dombrink-Kurtzman MA | Molecular dynamics simulations on the mycotoxin fumonisin B1. | 2001 | J. Agric. Food Chem. | pmid:11262071 |
| Schmidt K et al. | Regulated apical secretion of zymogens in rat pancreas. Involvement of the glycosylphosphatidylinositol-anchored glycoprotein GP-2, the lectin ZG16p, and cholesterol-glycosphingolipid-enriched microdomains. | 2001 | J. Biol. Chem. | pmid:11152672 |
| van der Westhuizen L et al. | The effect of repeated gavage doses of fumonisin B1 on the sphinganine and sphingosine levels in vervet monkeys. | 2001 | Toxicon | pmid:11223085 |
| Mathur S et al. | Fumonisin B(1) increases serum sphinganine concentration but does not alter serum sphingosine concentration or induce cardiovascular changes in milk-fed calves. | 2001 | Toxicol. Sci. | pmid:11248151 |
| Mathur S et al. | Fumonisin B(1) is hepatotoxic and nephrotoxic in milk-fed calves. | 2001 | Toxicol. Sci. | pmid:11248152 |
| Omurtag GZ | Determination of fumonisin B1 and B2 in corn and corn-based products in Turkey by high-performance liquid chromatography. | 2001 | J. Food Prot. | pmid:11456195 |
| Spotti M et al. | Fumonisin B1 metabolism by bovine liver microsomes. | 2001 | Vet. Res. Commun. | pmid:11519682 |
| Dilkin P et al. | Robotic automated clean-up for detection of fumonisins B1 and B2 in corn and corn-based feed by high-performance liquid chromatography. | 2001 | J Chromatogr A | pmid:11519801 |
| van der Westhuizen L et al. | The effect of a single gavage dose of fumonisin B(1) on the sphinganine and sphingosine levels in vervet monkeys. | 2001 Feb-Mar | Toxicon | pmid:10978745 |
| Hard GC et al. | Rat kidney pathology induced by chronic exposure to fumonisin B1 includes rare variants of renal tubule tumor. | 2001 May-Jun | Toxicol Pathol | pmid:11442024 |
| Whitaker TB et al. | Distribution among sample test results when testing shelled corn lots for fumonisin. | 2001 May-Jun | J AOAC Int | pmid:11417641 |
| Visconti A et al. | Determination of fumonisins B1 and B2 in corn and corn flakes by liquid chromatography with immunoaffinity column cleanup: collaborative study. | 2001 Nov-Dec | J AOAC Int | pmid:11767152 |
| Gelderblom WC et al. | Interaction of fumonisin B(1) and aflatoxin B(1) in a short-term carcinogenesis model in rat liver. | 2002 | Toxicology | pmid:11836022 |
| He Q et al. | Fumonisin B(1) alters sphingolipid metabolism and tumor necrosis factor alpha expression in heart and lung of mice. | 2002 | Life Sci. | pmid:12175895 |
| Bhandari N et al. | Temporal expression of fumonisin B(1)-induced tumor necrosis factor-alpha and interferon gamma in mice. | 2002 | Comp. Biochem. Physiol. C Toxicol. Pharmacol. | pmid:11879779 |
| Bhandari N et al. | Modulation of selected cell signaling genes in mouse liver by fumonisin B1. | 2002 | Chem. Biol. Interact. | pmid:11879819 |
| He Q et al. | Pharmacological antagonism of fumonisin B1 cytotoxicity in porcine renal epithelial cells (LLC-PK1): a model for reducing fumonisin-induced nephrotoxicity in vivo. | 2002 | Pharmacol. Toxicol. | pmid:12076308 |
| Bhandari N and Sharma RP | Fumonisin B(1)-induced alterations in cytokine expression and apoptosis signaling genes in mouse liver and kidney after an acute exposure. | 2002 | Toxicology | pmid:11882348 |
| Itakura A et al. | Ceramide and sphingosine rapidly induce apoptosis of murine mast cells supported by interleukin-3 and stem cell factor. | 2002 | Exp. Hematol. | pmid:11882365 |
| Theumer MG et al. | Immunobiological effects of fumonisin B1 in experimental subchronic mycotoxicoses in rats. | 2002 | Clin. Diagn. Lab. Immunol. | pmid:11777845 |
| Liu BH et al. | The effects of mycotoxins, fumonisin B1 and aflatoxin B1, on primary swine alveolar macrophages. | 2002 | Toxicol. Appl. Pharmacol. | pmid:12009859 |
| Trigo-Stockli DM et al. | Fumonisin B1 levels in 1995 and 1996 Kansas corn. | 2002 | Bull Environ Contam Toxicol | pmid:12068939 |
| Zomborszky-Kovács M et al. | Effects of prolonged exposure to low-dose fumonisin B1 in pigs. | 2002 | J. Vet. Med. B Infect. Dis. Vet. Public Health | pmid:12069274 |
| Almeida AP et al. | Mycoflora and fumonisin contamination in Brazilian corn from sowing to harvest. | 2002 | J. Agric. Food Chem. | pmid:12059175 |
| Voss KA et al. | Carcinogenicity and mechanism of action of fumonisin B1: a mycotoxin produced by Fusarium moniliforme (= F. verticillioides). | 2002 | Cancer Detect. Prev. | pmid:12088196 |
| Akao Y et al. | Ceramide accumulation is independent of camptothecin-induced apoptosis in prostate cancer LNCaP cells. | 2002 | Biochem. Biophys. Res. Commun. | pmid:12051721 |
| Gelderblom WC et al. | Lipids and delta6-desaturase activity alterations in rat liver microsomal membranes induced by fumonisin B1. | 2002 | Lipids | pmid:12458622 |
| Banczerowski-Pelyhe I et al. | Nerve conduction velocity and spinal reflexes may change in rats after fumonisin B1 exposure. | 2002 | Acta. Biol. Hung. | pmid:12501928 |
| Min JK et al. | Simultaneous quantitative analysis of sphingoid base 1-phosphates in biological samples by o-phthalaldehyde precolumn derivatization after dephosphorylation with alkaline phosphatase. | 2002 | Anal. Biochem. | pmid:11950216 |
| Bakan B et al. | Fungal growth and fusarium mycotoxin content in isogenic traditional maize and genetically modified maize grown in France and Spain. | 2002 | J. Agric. Food Chem. | pmid:11829636 |