fumonisin b1
fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
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Introduction
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with fumonisin b1?
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with fumonisin b1
PubChem Associated disorders and diseases
What pathways are associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with fumonisin b1?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with fumonisin b1?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with fumonisin b1?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with fumonisin b1?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with fumonisin b1?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with fumonisin b1
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Beier RC et al. | Calculated three dimensional structures of the fumonisin B1-4 mycotoxins. | 1995 | Bull Environ Contam Toxicol | pmid:7767023 |
| Pósa R et al. | Interaction of Bordetella bronchiseptica, Pasteurella multocida, and fumonisin B1 in the porcine respiratory tract as studied by computed tomography. | 2011 | Can. J. Vet. Res. | pmid:22210993 |
| Park MA et al. | Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation. | 2008 | Cancer Biol. Ther. | pmid:18787411 |
| Abnet CC et al. | Sphingolipids as biomarkers of fumonisin exposure and risk of esophageal squamous cell carcinoma in china. | 2001 | Cancer Causes Control | pmid:11714110 |
| Voss KA et al. | Carcinogenicity and mechanism of action of fumonisin B1: a mycotoxin produced by Fusarium moniliforme (= F. verticillioides). | 2002 | Cancer Detect. Prev. | pmid:12088196 |
| van der Westhuizen L et al. | Fumonisin B1 as a urinary biomarker of exposure in a maize intervention study among South African subsistence farmers. | 2011 | Cancer Epidemiol. Biomarkers Prev. | pmid:21266524 |
| Gong YY et al. | Association between tortilla consumption and human urinary fumonisin B1 levels in a Mexican population. | 2008 | Cancer Epidemiol. Biomarkers Prev. | pmid:18349288 |
| Gelderblom WC et al. | Cancer initiation by fumonisin B(1) in rat liver--role of cell proliferation. | 2001 | Cancer Lett. | pmid:11431101 |
| Gelderblom WC et al. | The cancer-promoting potential of fumonisin B1 in rat liver using diethylnitrosamine as a cancer initiator. | 1996 | Cancer Lett. | pmid:9020908 |
| Sahu SC et al. | Peroxidation of membrane lipids and oxidative DNA damage by fumonisin B1 in isolated rat liver nuclei. | 1998 | Cancer Lett. | pmid:9566705 |
| Lemmer ER et al. | The effects of dietary iron overload on fumonisin B1-induced cancer promotion in the rat liver. | 1999 | Cancer Lett. | pmid:10656628 |
| Takasaki M et al. | Cancer chemopreventive activity of euglobal-G1 from leaves of Eucalyptus grandis. | 2000 | Cancer Lett. | pmid:10814880 |
| Mehta R et al. | Glutathione S-transferase-placental form expression and proliferation of hepatocytes in fumonisin B1-treated male and female Sprague-Dawley rats. | 1998 | Cancer Lett. | pmid:9652790 |
| Blázquez C et al. | Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas. | 2004 | Cancer Res. | pmid:15313899 |
| Wang XZ et al. | Aberrant sphingolipid signaling is involved in the resistance of prostate cancer cell lines to chemotherapy. | 1999 | Cancer Res. | pmid:10582708 |
| Huang C et al. | Repression of protein kinase C and stimulation of cyclic AMP response elements by fumonisin, a fungal encoded toxin which is a carcinogen. | 1995 | Cancer Res. | pmid:7712470 |
| Garzotto M et al. | 12-O-tetradecanoylphorbol-13-acetate-induced apoptosis in LNCaP cells is mediated through ceramide synthase. | 1998 | Cancer Res. | pmid:9605775 |
| Blázquez C et al. | Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression. | 2008 | Cancer Res. | pmid:18339876 |
| Pinelli E et al. | Activation of mitogen-activated protein kinase by fumonisin B(1) stimulates cPLA(2) phosphorylation, the arachidonic acid cascade and cAMP production. | 1999 | Carcinogenesis | pmid:10469611 |
| Ramljak D et al. | A potential mechanism for fumonisin B(1)-mediated hepatocarcinogenesis: cyclin D1 stabilization associated with activation of Akt and inhibition of GSK-3beta activity. | 2000 | Carcinogenesis | pmid:10910956 |