fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hu J et al. | Inhibition of Fusarium solani Infection in Murine Keratocytes by Lactobacillus salivarius ssp. salivarius JCM1231 Culture Filtrate In Vitro. | 2017 | Curr. Eye Res. | pmid:28636459 |
Sharma RP et al. | Increased expression of CD95-ligand and other apoptotic signaling factors by fumonisin B1, a hepatotoxic mycotoxin, in livers of mice lacking tumor necrosis factor alpha. | 2003 | Cytokine | pmid:14596819 |
Sharma RP et al. | Mice lacking both TNFalpha receptors show increased constitutive expression of IFNgamma: a possible reason for lack of protection from fumonisin B1 hepatotoxicity. | 2006 | Cytokine | pmid:16884913 |
Maedler K et al. | Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function. | 2003 | Diabetes | pmid:12606514 |
Nakashita M et al. | Attenuation of acetic acid-induced gastric ulcer formation in rats by glucosylceramide synthase inhibitors. | 2013 | Dig. Dis. Sci. | pmid:22918683 |
Kim B et al. | Cytotoxicity of fumonisin B(1) in spheroid and monolayer cultures of rat hepatocytes. | 2008 | Drug Chem Toxicol | pmid:18622869 |
Petrinec Z et al. | Fumonisin B1 causes multiple lesions in common carp (Cyprinus carpio). | 2004 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:15503536 |
Shaheen HM et al. | The ceramide inhibitor fumonisin B1 mitigates the pulmonary effects of low-dose diesel exhaust inhalation in mice. | 2016 | Ecotoxicol. Environ. Saf. | pmid:27376354 |
Akiyama H et al. | [Comparison of several fluorescence HPLC methods for fumonisin analysis]. | 1994 | Eisei Shikenjo Hokoku | pmid:8854911 |
Jaffrézou JP et al. | Daunorubicin-induced apoptosis: triggering of ceramide generation through sphingomyelin hydrolysis. | 1996 | EMBO J. | pmid:8665849 |
Witty JP et al. | Induction of apoptotic cell death in hen granulosa cells by ceramide. | 1996 | Endocrinology | pmid:8940345 |
Njumbe Ediage E et al. | Multimycotoxin analysis in urines to assess infant exposure: a case study in Cameroon. | 2013 | Environ Int | pmid:23669720 |
Mayer S et al. | Occupational exposure to mould and microbial metabolites during onion sorting--insights into an overlooked workplace. | 2016 | Environ Monit Assess | pmid:26863887 |
Riley RT et al. | Sphingolipid perturbations as mechanisms for fumonisin carcinogenesis. | 2001 | Environ. Health Perspect. | pmid:11359699 |
Chelule PK et al. | Exposure of rural and urban populations in KwaZulu Natal, South Africa, to fumonisin B(1) in maize. | 2001 | Environ. Health Perspect. | pmid:11333186 |
Proceedings of the International Conference on the Toxicology of Fumonisin. 28-30 June 1999, Arlington, Virginia. | 2001 | Environ. Health Perspect. | pmid:11359690 | |
Marasas WF | Discovery and occurrence of the fumonisins: a historical perspective. | 2001 | Environ. Health Perspect. | pmid:11359691 |
ApSimon JW | Structure, synthesis, and biosynthesis of fumonisin B1 and related compounds. | 2001 | Environ. Health Perspect. | pmid:11359692 |
Haschek WM et al. | Fumonisin toxicosis in swine: an overview of porcine pulmonary edema and current perspectives. | 2001 | Environ. Health Perspect. | pmid:11359693 |
Myburg RB et al. | Cytotoxicity of fumonisin B1, diethylnitrosamine, and catechol on the SNO esophageal cancer cell line. | 2002 | Environ. Health Perspect. | pmid:12153764 |