fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
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Bouhet S et al. | The mycotoxin fumonisin B1 alters the proliferation and the barrier function of porcine intestinal epithelial cells. | 2004 | Toxicol. Sci. | pmid:14600282 |
He Q et al. | Silymarin protects against liver damage in BALB/c mice exposed to fumonisin B1 despite increasing accumulation of free sphingoid bases. | 2004 | Toxicol. Sci. | pmid:15103051 |
He Q et al. | Ceramide synthase inhibition by fumonisin B1 treatment activates sphingolipid-metabolizing systems in mouse liver. | 2006 | Toxicol. Sci. | pmid:16960033 |
Enongene EN et al. | Persistence and reversibility of the elevation in free sphingoid bases induced by fumonisin inhibition of ceramide synthase. | 2002 | Toxicol. Sci. | pmid:12011476 |
Voss KA et al. | Reproductive and sphingolipid metabolic effects of fumonisin B(1) and its alkaline hydrolysis product in LM/Bc mice: hydrolyzed fumonisin B(1) did not cause neural tube defects. | 2009 | Toxicol. Sci. | pmid:19783636 |
Mathur S et al. | Fumonisin B(1) increases serum sphinganine concentration but does not alter serum sphingosine concentration or induce cardiovascular changes in milk-fed calves. | 2001 | Toxicol. Sci. | pmid:11248151 |
Mathur S et al. | Fumonisin B(1) is hepatotoxic and nephrotoxic in milk-fed calves. | 2001 | Toxicol. Sci. | pmid:11248152 |
Bailly JD et al. | Toxicity of Fusarium moniliforme culture material containing known levels of fumonisin B1 in ducks. | 2001 | Toxicology | pmid:11376861 |
Sharma N et al. | Augmented fumonisin B1 toxicity in co-cultures: evidence for crosstalk between macrophages and non-parenchymatous liver epithelial cells involving proinflammatory cytokines. | 2004 | Toxicology | pmid:15363598 |
Stockmann-Juvala H et al. | Fumonisin B1-induced toxicity and oxidative damage in U-118MG glioblastoma cells. | 2004 | Toxicology | pmid:15337581 |
Creppy EE et al. | Synergistic effects of fumonisin B1 and ochratoxin A: are in vitro cytotoxicity data predictive of in vivo acute toxicity? | 2004 | Toxicology | pmid:15297026 |
Gelderblom WC et al. | Toxicological effects in rats chronically fed low dietary levels of fumonisin B(1). | 2001 | Toxicology | pmid:11295254 |
Domijan AM et al. | Standard and Fpg-modified comet assay in kidney cells of ochratoxin A- and fumonisin B(1)-treated rats. | 2006 | Toxicology | pmid:16497426 |
Theumer MG et al. | Subchronic mycotoxicoses in Wistar rats: assessment of the in vivo and in vitro genotoxicity induced by fumonisins and aflatoxin B(1), and oxidative stress biomarkers status. | 2010 | Toxicology | pmid:20015463 |
van der Westhuizen L et al. | Disruption of sphingolipid biosynthesis in hepatocyte nodules: selective proliferative stimulus induced by fumonisin B1. | 2004 | Toxicology | pmid:15158565 |
Gelderblom WC et al. | Cancer initiating properties of fumonisin B1 in a short-term rat liver carcinogenesis assay. | 2008 | Toxicology | pmid:18616970 |
Domijan AM et al. | Fumonisin B(1): oxidative status and DNA damage in rats. | 2007 | Toxicology | pmid:17291664 |
Biswal SS et al. | Changes in ceramide and sphingomyelin following fludarabine treatment of human chronic B-cell leukemia cells. | 2000 | Toxicology | pmid:11118669 |
He Q et al. | Fumonisin B1 hepatotoxicity in mice is attenuated by depletion of Kupffer cells by gadolinium chloride. | 2005 | Toxicology | pmid:15590129 |
Bhandari N et al. | Gender-related differences in subacute fumonisin B1 hepatotoxicity in BALB/c mice. | 2001 | Toxicology | pmid:11522378 |