fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Jiménez M et al. | Sugars and amino acids as factors affecting the synthesis of fumonisins in liquid cultures by isolates of the Gibberella fujikuroi complex. | 2003 | Int. J. Food Microbiol. | pmid:14623384 |
Okino N et al. | The reverse activity of human acid ceramidase. | 2003 | J. Biol. Chem. | pmid:12764132 |
Blomqvist M et al. | Selective lack of the C16:0 fatty acid isoform of sulfatide in pancreas of type II diabetic animal models. | 2003 | APMIS | pmid:14510644 |
Avantaggiato G et al. | Effects of muffin processing on fumonisins from 14C-labeled toxins produced in cultured corn kernels. | 2003 | J. Food Prot. | pmid:14572226 |
Sharma RP et al. | Increased expression of CD95-ligand and other apoptotic signaling factors by fumonisin B1, a hepatotoxic mycotoxin, in livers of mice lacking tumor necrosis factor alpha. | 2003 | Cytokine | pmid:14596819 |
Gopee NV et al. | Fumonisin B1-induced apoptosis is associated with delayed inhibition of protein kinase C, nuclear factor-kappaB and tumor necrosis factor alpha in LLC-PK1 cells. | 2003 | Chem. Biol. Interact. | pmid:14597127 |
Cirillo T et al. | Natural co-occurrence of deoxynivalenol and fumonisins B1 and B2 in Italian marketed foodstuffs. | 2003 | Food Addit Contam | pmid:12881130 |
Oswald IP et al. | Mycotoxin fumonisin B1 increases intestinal colonization by pathogenic Escherichia coli in pigs. | 2003 | Appl. Environ. Microbiol. | pmid:14532038 |
Sharma RP et al. | Deletion of IFN-gamma reduces fumonisin-induced hepatotoxicity in mice via alterations in inflammatory cytokines and apoptotic factors. | 2003 | J. Interferon Cytokine Res. | pmid:12639295 |
Litvak DA et al. | Modulators of ceramide metabolism sensitize colorectal cancer cells to chemotherapy: a novel treatment strategy. | 2003 | J. Gastrointest. Surg. | pmid:12559195 |
Suomalainen L et al. | Sphingosine-1-phosphate in inhibition of male germ cell apoptosis in the human testis. | 2003 | J. Clin. Endocrinol. Metab. | pmid:14602806 |
Maedler K et al. | Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function. | 2003 | Diabetes | pmid:12606514 |
Hinkovska-Galcheva V et al. | Enhanced phagocytosis through inhibition of de novo ceramide synthesis. | 2003 | J. Biol. Chem. | pmid:12424251 |
Cirillo T et al. | Evaluation of conventional and organic italian foodstuffs for deoxynivalenol and fumonisins B(1) and B(2). | 2003 | J. Agric. Food Chem. | pmid:14690407 |
Kim EK et al. | Hidden fumonisin in corn flakes. | 2003 | Food Addit Contam | pmid:12623665 |
Uchida Y et al. | De novo ceramide synthesis participates in the ultraviolet B irradiation-induced apoptosis in undifferentiated cultured human keratinocytes. | 2003 | J. Invest. Dermatol. | pmid:12648232 |
Beekrum S et al. | Naturally occurring phenols: a detoxification strategy for fumonisin B1. | 2003 | Food Addit Contam | pmid:12775468 |
Gopee NV and Sharma RP | Sphingoid bases and their phosphates: transient activation and delayed repression of protein kinase C isoforms and their possible involvement in fumonisin B1 cytotoxicity. | 2003 | Toxicology | pmid:12699912 |
Kritzinger Q et al. | Mycoflora and fumonisin mycotoxins associated with cowpea [Vigna unguiculata (L.) Walp] seeds. | 2003 | J. Agric. Food Chem. | pmid:12670154 |
Koyanagi S et al. | Elevation of de novo ceramide synthesis in tumor masses and the role of microsomal dihydroceramide synthase. | 2003 | Int. J. Cancer | pmid:12672022 |
Johnson VJ et al. | Increased susceptibility of renal epithelial cells to TNFalpha-induced apoptosis following treatment with fumonisin B1. | 2003 | Chem. Biol. Interact. | pmid:12732456 |
Pepeljnjak S et al. | Screening toxicity study in young carp (Cyprinus carpio L.) on feed amended with fumonisin B1. | 2003 | Mycopathologia | pmid:12733635 |
Tornyos G et al. | Effect of dietary fumonisin B1 on certain immune parameters of weaned pigs. | 2003 | Acta Vet. Hung. | pmid:12737044 |
Hering H et al. | Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability. | 2003 | J. Neurosci. | pmid:12716933 |
Williams LD et al. | Leaching and binding of fumonisins in soil microcosms. | 2003 | J. Agric. Food Chem. | pmid:12537442 |
Zhao H et al. | Anoxia and reoxygenation of human endothelial cells decrease ceramide glucosyltransferase expression and activates caspases. | 2003 | FASEB J. | pmid:12586734 |
Leung LW et al. | Inhibitors of glycosphingolipid biosynthesis reduce transepithelial electrical resistance in MDCK I and FRT cells. | 2003 | Am. J. Physiol., Cell Physiol. | pmid:12490435 |
Ho JA and Durst RA | Detection of fumonisin B1: comparison of flow-injection liposome immunoanalysis with high-performance liquid chromatography. | 2003 | Anal. Biochem. | pmid:12479829 |
Mobio TA et al. | Comparative study of the toxic effects of fumonisin B1 in rat C6 glioma cells and p53-null mouse embryo fibroblasts. | 2003 | Toxicology | pmid:12504343 |
Seefelder W et al. | Bound fumonisin B1: analysis of fumonisin-B1 glyco and amino acid conjugates by liquid chromatography-electrospray ionization-tandem mass spectrometry. | 2003 | J. Agric. Food Chem. | pmid:12926916 |
van der Westhuizen L et al. | Fumonisin contamination and fusarium incidence in corn from Santa Catarina, Brazil. | 2003 | J. Agric. Food Chem. | pmid:12926917 |
Riebeling C et al. | Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors. | 2003 | J. Biol. Chem. | pmid:12912983 |
Meyer K et al. | Residue formation of fumonisin B1 in porcine tissues. | 2003 | Food Addit Contam | pmid:12888389 |
Theumer MG et al. | Immunobiological effects of AFB1 and AFB1-FB1 mixture in experimental subchronic mycotoxicoses in rats. | 2003 | Toxicology | pmid:12604180 |
Shim WB et al. | Comparison of fumonisin B1 biosynthesis in maize germ and degermed kernels by Fusarium verticillioides. | 2003 | J. Food Prot. | pmid:14627291 |
Bird CB et al. | Determination of total fumonisins in corn by competitive direct enzyme-linked immunosorbent assay: collaborative study. | 2002 Mar-Apr | J AOAC Int | pmid:11990026 |
Broomhead JN et al. | Chronic effects of fumonisin B1 in broilers and turkeys fed dietary treatments to market age. | 2002 | Poult. Sci. | pmid:11885900 |
Ferrante MC et al. | Effect of fumonisin B1 on structure and function of macrophage plasma membrane. | 2002 | Toxicol. Lett. | pmid:11888701 |
Harvey B et al. | Toxicity of fumonisin from Fusarium verticillioides culture material and moniliformin from Fusarium fujikuroi culture material when fed singly and in combination to growing barrows. | 2002 | J. Food Prot. | pmid:11848570 |
Kozutsumi Y et al. | [Sphingolipid probe]. | 2002 | Tanpakushitsu Kakusan Koso | pmid:11915351 |
Poling SM et al. | N-(1-deoxy-D-fructos-1-yl) fumonisin B(1), the initial reaction product of fumonisin B(1) and D-glucose. | 2002 | J. Agric. Food Chem. | pmid:11853524 |
Gelderblom WC et al. | Interaction of fumonisin B(1) and aflatoxin B(1) in a short-term carcinogenesis model in rat liver. | 2002 | Toxicology | pmid:11836022 |
Lefrancois S et al. | The lysosomal transport of prosaposin requires the conditional interaction of its highly conserved d domain with sphingomyelin. | 2002 | J. Biol. Chem. | pmid:11856752 |
Brandwagt BF et al. | Overexpression of the tomato Asc-1 gene mediates high insensitivity to AAL toxins and fumonisin B1 in tomato hairy roots and confers resistance to Alternaria alternata f. sp. lycopersici in Nicotiana umbratica plants. | 2002 | Mol. Plant Microbe Interact. | pmid:11858172 |
He Q et al. | Fumonisin B(1) alters sphingolipid metabolism and tumor necrosis factor alpha expression in heart and lung of mice. | 2002 | Life Sci. | pmid:12175895 |
Rumora L et al. | Cytotoxic and genotoxic effects of fumonisin B1 on rabbit kidney RK13 cell line. | 2002 | Arch. Toxicol. | pmid:11875625 |
Bhandari N et al. | Temporal expression of fumonisin B(1)-induced tumor necrosis factor-alpha and interferon gamma in mice. | 2002 | Comp. Biochem. Physiol. C Toxicol. Pharmacol. | pmid:11879779 |
Bhandari N et al. | Modulation of selected cell signaling genes in mouse liver by fumonisin B1. | 2002 | Chem. Biol. Interact. | pmid:11879819 |
He Q et al. | Pharmacological antagonism of fumonisin B1 cytotoxicity in porcine renal epithelial cells (LLC-PK1): a model for reducing fumonisin-induced nephrotoxicity in vivo. | 2002 | Pharmacol. Toxicol. | pmid:12076308 |
Bhandari N and Sharma RP | Fumonisin B(1)-induced alterations in cytokine expression and apoptosis signaling genes in mouse liver and kidney after an acute exposure. | 2002 | Toxicology | pmid:11882348 |
Itakura A et al. | Ceramide and sphingosine rapidly induce apoptosis of murine mast cells supported by interleukin-3 and stem cell factor. | 2002 | Exp. Hematol. | pmid:11882365 |
Theumer MG et al. | Immunobiological effects of fumonisin B1 in experimental subchronic mycotoxicoses in rats. | 2002 | Clin. Diagn. Lab. Immunol. | pmid:11777845 |
Mahfoud R et al. | pH-dependent interaction of fumonisin B1 with cholesterol: physicochemical and molecular modeling studies at the air-water interface. | 2002 | J. Agric. Food Chem. | pmid:11782202 |
Wispriyono B et al. | A role for the de novo sphingolipids in apoptosis of photosensitized cells. | 2002 | Exp. Cell Res. | pmid:12213223 |
Chalfant CE et al. | De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1. | 2002 | J. Biol. Chem. | pmid:11801602 |
Howard PC et al. | Comparison of the toxicity of several fumonisin derivatives in a 28-day feeding study with female B6C3F(1) mice. | 2002 | Toxicol. Appl. Pharmacol. | pmid:12498732 |
Abbas HK et al. | Aflatoxin and fumonisin contamination of commercial corn (Zea mays) hybrids in Mississippi. | 2002 | J. Agric. Food Chem. | pmid:12188638 |
Trucksess MW et al. | Occurrence of aflatoxins and fumonisins in Incaparina from Guatemala. | 2002 | Food Addit Contam | pmid:12113662 |
Shephard GS et al. | Fumonisin B(1) in maize harvested in Iran during 1999. | 2002 | Food Addit Contam | pmid:12113663 |
Jenkins GM et al. | Acute activation of de novo sphingolipid biosynthesis upon heat shock causes an accumulation of ceramide and subsequent dephosphorylation of SR proteins. | 2002 | J. Biol. Chem. | pmid:12200446 |
Lu Y et al. | Characterization of fumonisin B(1)-glucose reaction kinetics and products. | 2002 | J. Agric. Food Chem. | pmid:12137505 |
Myburg RB et al. | Cytotoxicity of fumonisin B1, diethylnitrosamine, and catechol on the SNO esophageal cancer cell line. | 2002 | Environ. Health Perspect. | pmid:12153764 |
Caloni F et al. | Evaluation of Fumonisin B(1) and its metabolites absorption and toxicity on intestinal cells line Caco-2. | 2002 | Toxicon | pmid:12165322 |
Galvano F et al. | DNA damage in astrocytes exposed to fumonisin B1. | 2002 | Neurochem. Res. | pmid:11958538 |
Liu BH et al. | The effects of mycotoxins, fumonisin B1 and aflatoxin B1, on primary swine alveolar macrophages. | 2002 | Toxicol. Appl. Pharmacol. | pmid:12009859 |
Banczerowski-Pelyhe I et al. | In vivo and in vitro electrophysiological monitoring of rat neocortical activity after dietary fumonisin exposure. | 2002 | Mycopathologia | pmid:11998878 |
Ehrlich V et al. | Fumonisin B(1) is genotoxic in human derived hepatoma (HepG2) cells. | 2002 | Mutagenesis | pmid:11971998 |
Enongene EN et al. | Persistence and reversibility of the elevation in free sphingoid bases induced by fumonisin inhibition of ceramide synthase. | 2002 | Toxicol. Sci. | pmid:12011476 |
Smith GW et al. | Cardiovascular changes associated with intravenous administration of fumonisin B1 in horses. | 2002 | Am. J. Vet. Res. | pmid:11939316 |
Seefelder W et al. | Analysis of fumonisin B(1) in Fusarium proliferatum-infected asparagus spears and garlic bulbs from Germany by liquid chromatography-electrospray ionization mass spectrometry. | 2002 | J. Agric. Food Chem. | pmid:11982398 |
Venkataraman K et al. | Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells. | 2002 | J. Biol. Chem. | pmid:12105227 |
Kim EK et al. | Extraction of fumonisins B1 and B2 from white rice flour and their stability in white rice flour, cornstarch, cornmeal, and glucose. | 2002 | J. Agric. Food Chem. | pmid:12033838 |
Kim EK et al. | Survey for fumonisin B1 in Korean corn-based food products. | 2002 | Food Addit Contam | pmid:12028644 |
Broggi LE et al. | Distribution of fumonisins in dry-milled corn fractions in Argentina. | 2002 | Food Addit Contam | pmid:12028645 |
Trigo-Stockli DM et al. | Fumonisin B1 levels in 1995 and 1996 Kansas corn. | 2002 | Bull Environ Contam Toxicol | pmid:12068939 |
Zomborszky-Kovács M et al. | Effects of prolonged exposure to low-dose fumonisin B1 in pigs. | 2002 | J. Vet. Med. B Infect. Dis. Vet. Public Health | pmid:12069274 |
Almeida AP et al. | Mycoflora and fumonisin contamination in Brazilian corn from sowing to harvest. | 2002 | J. Agric. Food Chem. | pmid:12059175 |
Voss KA et al. | Carcinogenicity and mechanism of action of fumonisin B1: a mycotoxin produced by Fusarium moniliforme (= F. verticillioides). | 2002 | Cancer Detect. Prev. | pmid:12088196 |
Akao Y et al. | Ceramide accumulation is independent of camptothecin-induced apoptosis in prostate cancer LNCaP cells. | 2002 | Biochem. Biophys. Res. Commun. | pmid:12051721 |
Fotso J et al. | Production of beauvericin, moniliformin, fusaproliferin, and fumonisins b(1), b(2), and b(3) by fifteen ex-type strains of fusarium species. | 2002 | Appl. Environ. Microbiol. | pmid:12324376 |
Dresden-Osborne C and Noblet GP | Fumonisin B1 affects viability and alters nitric oxide production of a murine macrophage cell line. | 2002 | Int. Immunopharmacol. | pmid:12349946 |
Sadler TW et al. | Prevention of fumonisin B1-induced neural tube defects by folic acid. | 2002 | Teratology | pmid:12353213 |
Bhandari N et al. | Fumonisin B1-induced localized activation of cytokine network in mouse liver. | 2002 | Food Chem. Toxicol. | pmid:12387313 |
Desjardins AE et al. | FUM1--a gene required for fumonisin biosynthesis but not for maize ear rot and ear infection by Gibberella moniliformis in field tests. | 2002 | Mol. Plant Microbe Interact. | pmid:12423021 |
Cortez-Rocha MO et al. | Effect of extrusion processing on fumonisin B(1) and hydrolyzed fumonisin B(1) in contaminated alkali-cooked corn. | 2002 | Bull Environ Contam Toxicol | pmid:12232716 |
Le Stunff H et al. | Sphingosine-1-phosphate phosphohydrolase in regulation of sphingolipid metabolism and apoptosis. | 2002 | J. Cell Biol. | pmid:12235122 |
Camargos SM et al. | Accumulation of fumonisins B1 and B2 in freshly harvested Brazilian commercial maize at three locations during two nonconsecutive seasons. | 2002 | Mycopathologia | pmid:12650599 |
Gelderblom WC et al. | Lipids and delta6-desaturase activity alterations in rat liver microsomal membranes induced by fumonisin B1. | 2002 | Lipids | pmid:12458622 |
Banczerowski-Pelyhe I et al. | Nerve conduction velocity and spinal reflexes may change in rats after fumonisin B1 exposure. | 2002 | Acta. Biol. Hung. | pmid:12501928 |
Kong JY and Rabkin SW | Palmitate-induced cardiac apoptosis is mediated through CPT-1 but not influenced by glucose and insulin. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11788422 |
Min JK et al. | Simultaneous quantitative analysis of sphingoid base 1-phosphates in biological samples by o-phthalaldehyde precolumn derivatization after dephosphorylation with alkaline phosphatase. | 2002 | Anal. Biochem. | pmid:11950216 |
Gueguen G et al. | A lysophosphatidic acid analogue is revealed as a potent inhibitor of phosphatidylcholine synthesis, inducing apoptosis. | 2002 | Biochem. J. | pmid:12197836 |
Baron CL and Malhotra V | Role of diacylglycerol in PKD recruitment to the TGN and protein transport to the plasma membrane. | 2002 | Science | pmid:11729268 |
Galvano F et al. | DNA damage in human fibroblasts exposed to fumonisin B(1). | 2002 | Food Chem. Toxicol. | pmid:11731033 |
Bakan B et al. | Fungal growth and fusarium mycotoxin content in isogenic traditional maize and genetically modified maize grown in France and Spain. | 2002 | J. Agric. Food Chem. | pmid:11829636 |
Visconti A et al. | Determination of fumonisins B1 and B2 in corn and corn flakes by liquid chromatography with immunoaffinity column cleanup: collaborative study. | 2001 Nov-Dec | J AOAC Int | pmid:11767152 |
Hard GC et al. | Rat kidney pathology induced by chronic exposure to fumonisin B1 includes rare variants of renal tubule tumor. | 2001 May-Jun | Toxicol Pathol | pmid:11442024 |
Whitaker TB et al. | Distribution among sample test results when testing shelled corn lots for fumonisin. | 2001 May-Jun | J AOAC Int | pmid:11417641 |
van der Westhuizen L et al. | The effect of a single gavage dose of fumonisin B(1) on the sphinganine and sphingosine levels in vervet monkeys. | 2001 Feb-Mar | Toxicon | pmid:10978745 |