fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Sauviat MP et al. | Fumonisin, a toxin from the fungus Fusarium moniliforme sheld, blocks both the calcium current and the mechanical activity in frog atrial muscle. | 1991 | Toxicon | pmid:1658988 |
Voss KA et al. | The role of tumor necrosis factor alpha and the peroxisome proliferator-activated receptor alpha in modulating the effects of fumonisin in mouse liver. | 2006 | Toxicology | pmid:16574297 |
Wang S et al. | Rapid determination of fumonisin B1 in food samples by enzyme-linked immunosorbent assay and colloidal gold immunoassay. | 2006 | J. Agric. Food Chem. | pmid:16569033 |
German OL et al. | Ceramide is a mediator of apoptosis in retina photoreceptors. | 2006 | Invest. Ophthalmol. Vis. Sci. | pmid:16565407 |
Watanabe N and Lam E | Arabidopsis Bax inhibitor-1 functions as an attenuator of biotic and abiotic types of cell death. | 2006 | Plant J. | pmid:16507080 |
Bluhm BH and Woloshuk CP | Fck1, a C-type cyclin-dependent kinase, interacts with Fcc1 to regulate development and secondary metabolism in Fusarium verticillioides. | 2006 | Fungal Genet. Biol. | pmid:16504555 |
Domijan AM et al. | Standard and Fpg-modified comet assay in kidney cells of ochratoxin A- and fumonisin B(1)-treated rats. | 2006 | Toxicology | pmid:16497426 |
Samapundo S et al. | Influence of experimental parameters on the fluorescence response and recovery of the high-performance liquid chromatography analysis of fumonisin B1. | 2006 | J Chromatogr A | pmid:16494890 |
Gelderblom WC et al. | Toxicity and carcinogenicity of the Fusarium moniliforme metabolite, fumonisin B1, in rats. | 1991 | Carcinogenesis | pmid:1649015 |
Del Bianchi M et al. | Effects of prolonged oral administration of aflatoxin B1 and fumonisin B1 in broiler chickens. | 2005 | Poult. Sci. | pmid:16479938 |
Bluhm BH and Woloshuk CP | Amylopectin induces fumonisin B1 production by Fusarium verticillioides during colonization of maize kernels. | 2005 | Mol. Plant Microbe Interact. | pmid:16478053 |
Lino CM et al. | Determination of fumonisins B1 and B2 in Portuguese maize and maize-based samples by HPLC with fluorescence detection. | 2006 | Anal Bioanal Chem | pmid:16465502 |
Benedetti R et al. | Degradation of fumonisin B1 by a bacterial strain isolated from soil. | 2006 | Biodegradation | pmid:16453169 |
McKean C et al. | Comparative acute and combinative toxicity of aflatoxin B1 and fumonisin B1 in animals and human cells. | 2006 | Food Chem. Toxicol. | pmid:16427177 |
Sharma N et al. | Tumor necrosis factor alpha-mediated activation of c-Jun NH(2)-terminal kinase as a mechanism for fumonisin B(1) induced apoptosis in murine primary hepatocytes. | 2005 | J. Biochem. Mol. Toxicol. | pmid:16421893 |
Tran ST et al. | Serum sphinganine and the sphinganine to sphingosine ratio as a biomarker of dietary fumonisins during chronic exposure in ducks. | 2006 | Chem. Biol. Interact. | pmid:16413517 |
Tardieu D et al. | Effects of fumonisins on liver and kidney sphinganine and the sphinganine to sphingosine ratio during chronic exposure in ducks. | 2006 | Chem. Biol. Interact. | pmid:16412405 |
Itoh Y et al. | Involvement of de novo ceramide synthesis in radiocontrast-induced renal tubular cell injury. | 2006 | Kidney Int. | pmid:16408118 |
Sakamoto H et al. | Host sphingolipid biosynthesis as a target for hepatitis C virus therapy. | 2005 | Nat. Chem. Biol. | pmid:16408072 |
Deshmukh S et al. | Individual and combined effects of Fusarium moniliforme culture material, containing known levels of fumonisin B1, and Salmonella gallinarum infection on liver of Japanese quail. | 2005 | Avian Dis. | pmid:16405006 |
Wang E et al. | Increases in serum sphingosine and sphinganine and decreases in complex sphingolipids in ponies given feed containing fumonisins, mycotoxins produced by Fusarium moniliforme. | 1992 | J. Nutr. | pmid:1640265 |
Chang MC et al. | Inhibition of sphingolipid synthesis affects kinetics but not fidelity of L1/NgCAM transport along direct but not transcytotic axonal pathways. | 2006 | Mol. Cell. Neurosci. | pmid:16376103 |
Pepeljnjak S et al. | Toxic effects of Ustilago maydis and fumonisin B1 in rats. | 2005 | Acta Pharm | pmid:16375823 |
Schulz A et al. | The CLN9 protein, a regulator of dihydroceramide synthase. | 2006 | J. Biol. Chem. | pmid:16303764 |
Shephard GS et al. | Fumonisin mycotoxins in traditional Xhosa maize beer in South Africa. | 2005 | J. Agric. Food Chem. | pmid:16302789 |
Shephard GS et al. | Initial studies on the toxicokinetics of fumonisin B1 in rats. | 1992 | Food Chem. Toxicol. | pmid:1628862 |
Brown TP et al. | Fumonisin mycotoxicosis in broilers: performance and pathology. | 1992 Apr-Jun | Avian Dis. | pmid:1627116 |
Soriano JM et al. | Mechanism of action of sphingolipids and their metabolites in the toxicity of fumonisin B1. | 2005 | Prog. Lipid Res. | pmid:16266752 |
Sánchez-Rangel D et al. | Fumonisin production by Fusarium verticillioides strains isolated from maize in Mexico and development of a polymerase chain reaction to detect potential toxigenic strains in grains. | 2005 | J. Agric. Food Chem. | pmid:16248554 |
Caloni F et al. | In vitro study with Caco-2 cells on fumonisin B1: aminopentol intestinal passage and role of P-glycoprotein. | 2005 | Vet. Res. Commun. | pmid:16244976 |
Cabassi E et al. | Intoxication with fumonisin B1 (FB1) in piglets and supplementation with granulated activated carbon: cellular-mediated immunoresponse. | 2005 | Vet. Res. Commun. | pmid:16244961 |
Cavaglieri L et al. | In vitro influence of bacterial mixtures on Fusarium verticillioides growth and fumonisin B1 production: effect of seeds treatment on maize root colonization. | 2005 | Lett. Appl. Microbiol. | pmid:16238641 |
Xia QZ et al. | [Spontaneous and induced programmed cell death in suspension cell cultures of cotton (Gossypium hirsutum L.)]. | 2005 | Shi Yan Sheng Wu Xue Bao | pmid:16231696 |
Voss KA et al. | Toxic effects of fumonisin in mouse liver are independent of the peroxisome proliferator-activated receptor alpha. | 2006 | Toxicol. Sci. | pmid:16221962 |
Chivasa S et al. | Extracellular ATP functions as an endogenous external metabolite regulating plant cell viability. | 2005 | Plant Cell | pmid:16199612 |
Desjardins AE et al. | Identification and heritability of fumonisin insensitivity in Zea mays. | 2005 | Phytochemistry | pmid:16198380 |
Shephard GS et al. | Determination of fumonisin B1 in plasma and urine by high-performance liquid chromatography. | 1992 | J. Chromatogr. | pmid:1618963 |
Norred WP et al. | Effects of selected secondary metabolites of Fusarium moniliforme on unscheduled synthesis of DNA by rat primary hepatocytes. | 1992 | Food Chem. Toxicol. | pmid:1618447 |
Cvetnić Z et al. | Toxigenic potential of Fusarium species isolated from non-harvested maize. | 2005 | Arh Hig Rada Toksikol | pmid:16180614 |
Sharma RP et al. | Lupus-prone NZBWF1/J mice, defective in cytokine signaling, are resistant to fumonisin hepatotoxicity despite accumulation of liver sphinganine. | 2005 | Toxicology | pmid:16159691 |
Hwang D et al. | Effects of ceramide inhibition on experimental radiation-induced oral mucositis. | 2005 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod | pmid:16122660 |
Deshmukh S et al. | Effects of Fusarium moniliforme culture material containing known levels of fumonisin B1 on progress of Salmonella Gallinarum infection in Japanese quail: clinical signs and hematologic studies. | 2005 | Avian Dis. | pmid:16094834 |
Tani M et al. | Mechanisms of sphingosine and sphingosine 1-phosphate generation in human platelets. | 2005 | J. Lipid Res. | pmid:16061940 |
He Q and Sharma RP | Inhibition of tumor necrosis factor alpha signaling by anti-tumor necrosis factor alpha antibodies and pentoxifylline is unable to prevent fumonisin hepatotoxicity in mice. | 2005 | Toxicon | pmid:16054185 |
Rossi F et al. | Effect of Bt corn on broiler growth performance and fate of feed-derived DNA in the digestive tract. | 2005 | Poult. Sci. | pmid:16050119 |
Kuroyanagi M et al. | Vacuolar processing enzyme is essential for mycotoxin-induced cell death in Arabidopsis thaliana. | 2005 | J. Biol. Chem. | pmid:16043487 |
Piva A et al. | Activated carbon does not prevent the toxicity of culture material containing fumonisin B1 when fed to weanling piglets. | 2005 | J. Anim. Sci. | pmid:16024715 |
Liu C et al. | Occurrence of fumonisins B1 and B2 in asparagus from Shandong province, PR China. | 2005 | Food Addit Contam | pmid:16019842 |
Kouadio JH et al. | Comparative study of cytotoxicity and oxidative stress induced by deoxynivalenol, zearalenone or fumonisin B1 in human intestinal cell line Caco-2. | 2005 | Toxicology | pmid:16019124 |
Osuchowski MF and Sharma RP | Fumonisin B1 induces necrotic cell death in BV-2 cells and murine cultured astrocytes and is antiproliferative in BV-2 cells while N2A cells and primary cortical neurons are resistant. | 2005 | Neurotoxicology | pmid:16005069 |
Javed T et al. | Comparative pathologic changes in broiler chicks on feed amended with Fusarium proliferatum culture material or purified fumonisin B1 and moniliformin. | 2005 | Mycopathologia | pmid:15983742 |
Halloy DJ et al. | Oral exposure to culture material extract containing fumonisins predisposes swine to the development of pneumonitis caused by Pasteurellamultocida. | 2005 | Toxicology | pmid:15979225 |
Paepens C et al. | Development of a liquid chromatography/tandem mass spectrometry method for the quantification of fumonisin B1, B2 and B3 in cornflakes. | 2005 | Rapid Commun. Mass Spectrom. | pmid:15973649 |
Gelineau-van Waes J et al. | Maternal fumonisin exposure and risk for neural tube defects: mechanisms in an in vivo mouse model. | 2005 | Birth Defects Res. Part A Clin. Mol. Teratol. | pmid:15959874 |
Cavaglieri L et al. | Biocontrol of Bacillus subtilis against Fusarium verticillioides in vitro and at the maize root level. | 2005 Jun-Jul | Res. Microbiol. | pmid:15950130 |
Wang L et al. | OsLSD1, a rice zinc finger protein, regulates programmed cell death and callus differentiation. | 2005 | Mol. Plant Microbe Interact. | pmid:15915636 |
Osuchowski MF et al. | Endotoxin exposure alters brain and liver effects of fumonisin B1 in BALB/c mice: implication of blood brain barrier. | 2005 | Food Chem. Toxicol. | pmid:15913876 |
Fernández-Surumay G et al. | Fumonisin B-glucose reaction products are less toxic when fed to swine. | 2005 | J. Agric. Food Chem. | pmid:15884870 |
Petrache I et al. | Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice. | 2005 | Nat. Med. | pmid:15852018 |
He Q et al. | Myriocin prevents fumonisin B1-induced sphingoid base accumulation in mice liver without ameliorating hepatotoxicity. | 2005 | Food Chem. Toxicol. | pmid:15811577 |
Cavaglieri LR et al. | Rhizobacteria and their potential to control Fusarium verticillioides: effect of maize bacterisation and inoculum density. | 2005 | Antonie Van Leeuwenhoek | pmid:15803383 |
Park JW et al. | Analysis of heat-processed corn foods for fumonisins and bound fumonisins. | 2004 | Food Addit Contam | pmid:15799562 |
Pagliuca G et al. | Simple method for the simultaneous isolation and determination of fumonisin B1 and its metabolite aminopentol-1 in swine liver by liquid chromatography--fluorescence detection. | 2005 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:15797527 |
Shimamoto S et al. | Changes in ganglioside content affect the binding of Clostridium perfringens epsilon-toxin to detergent-resistant membranes of Madin-Darby canine kidney cells. | 2005 | Microbiol. Immunol. | pmid:15781998 |
Cetin Y and Bullerman LB | Cytotoxicity of Fusarium mycotoxins to mammalian cell cultures as determined by the MTT bioassay. | 2005 | Food Chem. Toxicol. | pmid:15778016 |
Lerda D et al. | Fumonisins in foods from Cordoba (Argentina), presence and genotoxicity. | 2005 | Food Chem. Toxicol. | pmid:15778008 |
Cortez-Rocha MO et al. | Occurrence of fumonisin B1 and hydrolyzed fumonisin B1 in Mexican nixtamalized cornmeal. | 2005 | Bull Environ Contam Toxicol | pmid:15768501 |
Nelson PE et al. | Fumonisin B1 production by Fusarium species other than F. moniliforme in section Liseola and by some related species. | 1992 | Appl. Environ. Microbiol. | pmid:1575501 |
Castoria R et al. | Occurrence of mycotoxin in Farro samples from southern Italy. | 2005 | J. Food Prot. | pmid:15726990 |
Osuchowski MF et al. | Fumonisin B1-induced neurodegeneration in mice after intracerebroventricular infusion is concurrent with disruption of sphingolipid metabolism and activation of proinflammatory signaling. | 2005 | Neurotoxicology | pmid:15713342 |
Lauer B et al. | Production of a single-chain variable fragment antibody against fumonisin B1. | 2005 | J. Agric. Food Chem. | pmid:15712995 |
Gutiérrez-Nájera N et al. | Fumonisin B1, a sphingoid toxin, is a potent inhibitor of the plasma membrane H+-ATPase. | 2005 | Planta | pmid:15703925 |
Stone JM et al. | Arabidopsis AtSPL14, a plant-specific SBP-domain transcription factor, participates in plant development and sensitivity to fumonisin B1. | 2005 | Plant J. | pmid:15703061 |
López AG et al. | Aromatic plants essential oils activity on Fusarium verticillioides Fumonisin B(1) production in corn grain. | 2004 | Mycopathologia | pmid:15702272 |
Butkeraitis P et al. | Effect of dietary fumonisin B1 on laying Japanese quail. | 2004 | Br. Poult. Sci. | pmid:15697020 |
Tran ST et al. | Chronic effects of fumonisin B1 on ducks. | 2005 | Poult. Sci. | pmid:15685938 |
Miazzo R et al. | Efficacy of sodium bentonite as a detoxifier of broiler feed contaminated with aflatoxin and fumonisin. | 2005 | Poult. Sci. | pmid:15685935 |
De Angelis I et al. | Absorption of fumonisin B1 and aminopentol on an in vitro model of intestinal epithelium; the role of P-glycoprotein. | 2005 | Toxicon | pmid:15683866 |
Suga K et al. | [Analysis of fumonisin B1 and B2 in beer and raw materials of beer by liquid chromatography/tandem mass spectrometry]. | 2004 | Shokuhin Eiseigaku Zasshi | pmid:15678940 |
Fernández-Surumay G et al. | Glucose reaction with fumonisin B1 partially reduces its toxicity in swine. | 2004 | J. Agric. Food Chem. | pmid:15675827 |
Nikièma PN et al. | Fumonisin contamination of maize in Burkina Faso, West Africa. | 2004 | Food Addit Contam | pmid:15666980 |
Cabrera RM et al. | Investigations into the etiology of neural tube defects. | 2004 | Birth Defects Res. C Embryo Today | pmid:15662706 |
Taranu I et al. | Mycotoxin fumonisin B1 alters the cytokine profile and decreases the vaccinal antibody titer in pigs. | 2005 | Toxicol. Sci. | pmid:15659571 |
Ono EY et al. | Trends of fumonisin contamination and animal intoxication through monitoring 1991 to 1997 corn crop in the State of Paraná, Brazil. | 2004 | Mycopathologia | pmid:15630554 |
Stockmann-Juvala H et al. | Oxidative stress induced by fumonisin B1 in continuous human and rodent neural cell cultures. | 2004 | Free Radic. Res. | pmid:15621711 |
Ogido R et al. | Effects of prolonged administration of aflatoxin B1 and fumonisin B1 in laying Japanese quail. | 2004 | Poult. Sci. | pmid:15615006 |
Hinojo MJ et al. | Utility of the polymerase chain reaction-restriction fragment length polymorphisms of the intergenic spacer region of the rDNA for characterizing Gibberella fujikuroi isolates. | 2004 | Syst. Appl. Microbiol. | pmid:15612625 |
Sharma N et al. | Sphingosine kinase activity confers resistance to apoptosis by fumonisin B1 in human embryonic kidney (HEK-293) cells. | 2004 | Chem. Biol. Interact. | pmid:15607760 |
He Q et al. | Fumonisin B1 hepatotoxicity in mice is attenuated by depletion of Kupffer cells by gadolinium chloride. | 2005 | Toxicology | pmid:15590129 |
De Liguoro M et al. | Field observations in pigs exposed to fumonisin B1 contaminated feed. | 2004 | Vet Hum Toxicol | pmid:15587243 |
Rentz SS et al. | Inhibition of sphingolipid biosynthesis decreases phosphorylated ERK2 in LLC-PK1 cells. | 2005 | Food Chem. Toxicol. | pmid:15582204 |
Osweiler GD et al. | Characterization of an epizootic of pulmonary edema in swine associated with fumonisin in corn screenings. | 1992 | J. Vet. Diagn. Invest. | pmid:1554770 |
Becker KP et al. | Selective inhibition of juxtanuclear translocation of protein kinase C betaII by a negative feedback mechanism involving ceramide formed from the salvage pathway. | 2005 | J. Biol. Chem. | pmid:15546881 |
Yu MU et al. | Altered de novo sphingolipid biosynthesis is involved in the serum deprivation-induced cell death in LLC-PK1 cells. | 2004 | J. Toxicol. Environ. Health Part A | pmid:15513905 |
Petrinec Z et al. | Fumonisin B1 causes multiple lesions in common carp (Cyprinus carpio). | 2004 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:15503536 |
Cavaglieri L et al. | Screening procedures for selecting rhizobacteria with biocontrol effects upon Fusarium verticillioides growth and fumonisin B1 production. | 2004 | Res. Microbiol. | pmid:15501652 |
Gopee NV and Sharma RP | The mycotoxin fumonisin B1 transiently activates nuclear factor-kappaB, tumor necrosis factor alpha and caspase 3 via protein kinase Calpha-dependent pathway in porcine renal epithelial cells. | 2004 | Cell Biol. Toxicol. | pmid:15499968 |
Yi F et al. | Homocysteine activates NADH/NADPH oxidase through ceramide-stimulated Rac GTPase activity in rat mesangial cells. | 2004 | Kidney Int. | pmid:15496169 |
Vismer HF et al. | Production of fumonisins by Fusarium verticillioides strains on solid and in a defined liquid medium--effects of L-methionine and inoculum. | 2004 | Mycopathologia | pmid:15487327 |
Fornelli F et al. | Cytotoxicity induced by nivalenol, deoxynivalenol, and fumonisin B1 in the SF-9 insect cell line. | 2004 May-Jun | In Vitro Cell. Dev. Biol. Anim. | pmid:15479121 |