fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Bondy GS et al. | Gavage administration of the fungal toxin fumonisin B1 to female Sprague-Dawley rats. | 1998 | J. Toxicol. Environ. Health Part A | pmid:9444317 |
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Collins TF et al. | Effects of fumonisin B1 in pregnant rats. | 1998 | Food Chem. Toxicol. | pmid:9662415 |
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Atroshi F et al. | Effects of tamoxifen, melatonin, coenzyme Q10, and L-carnitine supplementation on bacterial growth in the presence of mycotoxins. | 1998 | Pharmacol. Res. | pmid:9774492 |
Yin JJ et al. | Effects of fumonisin B1 on lipid peroxidation in membranes. | 1998 | Biochim. Biophys. Acta | pmid:9565668 |
Sahu SC et al. | Peroxidation of membrane lipids and oxidative DNA damage by fumonisin B1 in isolated rat liver nuclei. | 1998 | Cancer Lett. | pmid:9566705 |
Mullett W et al. | Immunoassay of fumonisins by a surface plasmon resonance biosensor. | 1998 | Anal. Biochem. | pmid:9570825 |
Lemmer ER et al. | Poor reporting of oocyte apoptosis. | 1998 | Nat. Med. | pmid:9546766 |
Shetty PH and Bhat RV | Sensitive method for the detection of fumonisin B1 in human urine. | 1998 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:9498687 |
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Isogai C et al. | Analysis of bax protein in sphingosine-induced apoptosis in the human leukemic cell line TF1 and its bcl-2 transfectants. | 1998 | Exp. Hematol. | pmid:9808050 |
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Konoshima T et al. | Anti-tumor-promoting activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. (I). | 1998 | Biol. Pharm. Bull. | pmid:9743252 |
Charoenpornsook K et al. | The effects of four mycotoxins on the mitogen stimulated proliferation of bovine peripheral blood mononuclear cells in vitro. | 1998 | Mycopathologia | pmid:10205890 |
Abeywickrama K et al. | Effects of Fusarium moniliforme culture extracts and fumonisin B1 on DNA, RNA and protein synthesis by baby hamster kidney cells. | 1998 | Mycopathologia | pmid:10205886 |
Rösner H | Significance of gangliosides in neuronal differentiation of neuroblastoma cells and neurite growth in tissue culture. | 1998 | Ann. N. Y. Acad. Sci. | pmid:9668353 |
Hatch GM and McClarty G | Phospholipid composition of purified Chlamydia trachomatis mimics that of the eucaryotic host cell. | 1998 | Infect. Immun. | pmid:9673255 |
Ueda N et al. | Role of enhanced ceramide generation in DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells. | 1998 | Kidney Int. | pmid:9690206 |
Schwarz A and Futerman AH | Inhibition of sphingolipid synthesis, but not degradation, alters the rate of dendrite growth in cultured hippocampal neurons. | 1998 | Brain Res. Dev. Brain Res. | pmid:9693790 |
Garzotto M et al. | 12-O-tetradecanoylphorbol-13-acetate-induced apoptosis in LNCaP cells is mediated through ceramide synthase. | 1998 | Cancer Res. | pmid:9605775 |
Abado-Becognee K et al. | Cytotoxicity of fumonisin B1: implication of lipid peroxidation and inhibition of protein and DNA syntheses. | 1998 | Arch. Toxicol. | pmid:9587019 |
Fazekas B et al. | Fumonisin B1 contamination of maize and experimental acute fumonisin toxicosis in pigs. | 1998 | Zentralblatt Veterinarmedizin Reihe B | pmid:9588111 |
Castelo MM et al. | Occurrence of fumonisins in corn-based food products. | 1998 | J. Food Prot. | pmid:9709253 |
Gamen S et al. | Granulysin-induced apoptosis. I. Involvement of at least two distinct pathways. | 1998 | J. Immunol. | pmid:9712041 |
Castelo MM et al. | Stability of fumonisins in thermally processed corn products. | 1998 | J. Food Prot. | pmid:9713766 |
Mehta R et al. | Glutathione S-transferase-placental form expression and proliferation of hepatocytes in fumonisin B1-treated male and female Sprague-Dawley rats. | 1998 | Cancer Lett. | pmid:9652790 |
Lee JY et al. | Cell-cycle-dependent changes in ceramide levels preceding retinoblastoma protein dephosphorylation in G2/M. | 1998 | Biochem. J. | pmid:9716505 |
Shephard GS | Chromatographic determination of the fumonisin mycotoxins. | 1998 | J Chromatogr A | pmid:9718704 |
Schmelz EM et al. | Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases. | 1998 | Toxicol. Appl. Pharmacol. | pmid:9473533 |
Duncan K et al. | Improved fluorometric and chromatographic methods for the quantification of fumonisins B(1), B(2) and B(3). | 1998 | J Chromatogr A | pmid:9718705 |
Rosiles MR et al. | An outbreak of equine leukoencephalomalacia at Oaxaca, Mexico, associated with fumonisin B1. | 1998 | Zentralbl Veterinarmed A | pmid:9719762 |
DiPietrantonio AM et al. | Regulation of G1/S transition and induction of apoptosis in HL-60 leukemia cells by fenretinide (4HPR). | 1998 | Int. J. Cancer | pmid:9724094 |
Gamen S et al. | Caspases are the main executioners of Fas-mediated apoptosis, irrespective of the ceramide signalling pathway. | 1998 | Cell Death Differ. | pmid:10200470 |
Voss KA et al. | In vivo effects of fumonisin B1-producing and fumonisin B1-nonproducing Fusarium moniliforme isolates are similar: fumonisins B2 and B3 cause hepato- and nephrotoxicity in rats. | 1998 | Mycopathologia | pmid:9725030 |
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Gurung NK et al. | Effects of fumonisin B1-contaminated feeds on weanling angora goats. | 1998 | J. Anim. Sci. | pmid:9856397 |
Auzenne E et al. | Cytotoxic effects of sphingolipids as single or multi-modality agents on human melanoma and soft tissue sarcoma in vitro. | 1998 | Melanoma Res. | pmid:9664144 |
Tsunoda M et al. | Early fumonisin B1 toxicity in relation to disrupted sphingolipid metabolism in male BALB/c mice. | 1998 | J. Biochem. Mol. Toxicol. | pmid:9664234 |
Humpf HU et al. | Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor. | 1998 | J. Biol. Chem. | pmid:9668088 |
Abel S and Gelderblom WC | Oxidative damage and fumonisin B1-induced toxicity in primary rat hepatocytes and rat liver in vivo. | 1998 | Toxicology | pmid:9928627 |
van der Westhuizen L et al. | Inhibition of sphingolipid biosynthesis in rat primary hepatocyte cultures by fumonisin B1 and other structurally related compounds. | 1998 | Food Chem. Toxicol. | pmid:9674957 |
Kutuzov MA et al. | Expression and characterization of PP7, a novel plant protein Ser/Thr phosphatase distantly related to RdgC/PPEF and PP5. | 1998 | FEBS Lett. | pmid:9862444 |
Munkvold G et al. | Occurrence of fusaproliferin and beauvericin in Fusarium-contaminated livestock feed in Iowa. | 1998 | Appl. Environ. Microbiol. | pmid:9758820 |
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de Nijs M et al. | Assessment of human exposure to fumonisin B1. | 1998 | J. Food Prot. | pmid:9678173 |
Tsunoda M et al. | Fumonisin B1-induced increases in neurotransmitter metabolite levels in different brain regions of BALB/c mice. | 1998 | Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. | pmid:9827064 |
Akiyama H et al. | Quantitation of fumonisins in corn by HPLC with o-phthalaldehyde postcolumn derivatization and their identification by LC/MS. | 1997-1998 | Mycopathologia | pmid:9735014 |
Bondy GS et al. | Toxicity of fumonisin B1 to B6C3F1 mice: a 14-day gavage study. | 1997 Oct-Nov | Food Chem. Toxicol. | pmid:9463532 |
Hlywka JJ et al. | The use of the chicken embryo screening test and brine shrimp (Artemia salina) bioassays to assess the toxicity of fumonisin B1 mycotoxin. | 1997 Oct-Nov | Food Chem. Toxicol. | pmid:9463533 |
Kwon OS et al. | Effects of fumonisin B1 treatment on blood-brain barrier transfer in developing rats. | 1997 Mar-Apr | Neurotoxicol Teratol | pmid:9136132 |
Piñeiro MS et al. | Fumonisin levels in Uruguayan corn products. | 1997 Jul-Aug | J AOAC Int | pmid:9241845 |
Espada Y et al. | Fumonisin mycotoxicosis in broilers: plasma proteins and coagulation modifications. | 1997 Jan-Mar | Avian Dis. | pmid:9087322 |
Scudamore KA et al. | Determination of mycotoxins in pet foods sold for domestic pets and wild birds using linked-column immunoassay clean-up and HPLC. | 1997 Feb-Mar | Food Addit Contam | pmid:9102350 |
Bermudez AJ et al. | The individual and combined effects of the Fusarium mycotoxins moniliformin and fumonisin B1 in turkeys. | 1997 Apr-Jun | Avian Dis. | pmid:9201392 |
Flynn TJ et al. | Assessment of the embryotoxic potential of the total hydrolysis product of fumonisin B1 using cultured organogenesis-staged rat embryos. | 1997 | Food Chem. Toxicol. | pmid:9449218 |
Ueno Y et al. | Fumonisins as a possible contributory risk factor for primary liver cancer: a 3-year study of corn harvested in Haimen, China, by HPLC and ELISA. | 1997 | Food Chem. Toxicol. | pmid:9449219 |
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Tryphonas H et al. | Effects of fumonisin B1 on the immune system of sprague-dawley rats following a 14-day oral (gavage) exposure. | 1997 | Fundam Appl Toxicol | pmid:9325027 |
Stevens VL and Tang J | Fumonisin B1-induced sphingolipid depletion inhibits vitamin uptake via the glycosylphosphatidylinositol-anchored folate receptor. | 1997 | J. Biol. Chem. | pmid:9218430 |
Ferguson SA et al. | Prenatal fumonisin (FB1) treatment in rats results in minimal maternal or offspring toxicity. | 1997 | Neurotoxicology | pmid:9291504 |
Tseng TC and Liu CY | Occurrence of fumonisin B1 and B2 in corn-based foodstuffs in Taiwan market. | 1997 | Mycopathologia | pmid:9299759 |
Gelderblom WC et al. | Effect of fumonisin B1 on the levels and fatty acid composition of selected lipids in rat liver in vivo. | 1997 | Food Chem. Toxicol. | pmid:9301647 |
Suzuki A et al. | Sequential operation of ceramide synthesis and ICE cascade in CPT-11-initiated apoptotic death signaling. | 1997 | Exp. Cell Res. | pmid:9184074 |
Guzman RE et al. | Dietary Fusarium moniliforme culture material induces in vitro tumor necrosis factor-alpha like activity in the sera of swine. | 1997 | Immunopharmacol Immunotoxicol | pmid:9130010 |
Wu W and Vesonder RF | Inhibition of gluconeogenesis in cultured chicken embryo hepatocytes by Fusarium metabolites. | 1997 | Nat. Toxins | pmid:9131594 |
Melcion D et al. | Study of the biosynthesis of fumonisins B1, B2 and B3 by different strains of Fusarium moniliforme. | 1997 | Lett. Appl. Microbiol. | pmid:9134779 |
LaBorde JB et al. | Lack of embryotoxicity of fumonisin B1 in New Zealand white rabbits. | 1997 | Fundam Appl Toxicol | pmid:9398494 |
Wild CP et al. | Absence of a synergistic effect between fumonisin B1 and N-nitrosomethylbenzylamine in the induction of oesophageal papillomas in the rat. | 1997 | Nat. Toxins | pmid:9285918 |
Kubena LF et al. | Individual and combined effects of fumonisin B1 present in Fusarium moniliforme culture material and T-2 toxin or deoxynivalenol in broiler chicks. | 1997 | Poult. Sci. | pmid:9276886 |
Jiménez M and Mateo R | Determination of mycotoxins produced by Fusarium isolates from banana fruits by capillary gas chromatography and high-performance liquid chromatography. | 1997 | J Chromatogr A | pmid:9299747 |
Bhat RV et al. | A foodborne disease outbreak due to the consumption of moldy sorghum and maize containing fumonisin mycotoxins. | 1997 | J. Toxicol. Clin. Toxicol. | pmid:9140318 |