fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
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Taranu I et al. | Mycotoxin fumonisin B1 alters the cytokine profile and decreases the vaccinal antibody titer in pigs. | 2005 | Toxicol. Sci. | pmid:15659571 |
Osuchowski MF et al. | Fumonisin B1-induced neurodegeneration in mice after intracerebroventricular infusion is concurrent with disruption of sphingolipid metabolism and activation of proinflammatory signaling. | 2005 | Neurotoxicology | pmid:15713342 |
Castoria R et al. | Occurrence of mycotoxin in Farro samples from southern Italy. | 2005 | J. Food Prot. | pmid:15726990 |
De Angelis I et al. | Absorption of fumonisin B1 and aminopentol on an in vitro model of intestinal epithelium; the role of P-glycoprotein. | 2005 | Toxicon | pmid:15683866 |
Gutiérrez-Nájera N et al. | Fumonisin B1, a sphingoid toxin, is a potent inhibitor of the plasma membrane H+-ATPase. | 2005 | Planta | pmid:15703925 |
Lauer B et al. | Production of a single-chain variable fragment antibody against fumonisin B1. | 2005 | J. Agric. Food Chem. | pmid:15712995 |
Osuchowski MF et al. | Endotoxin exposure alters brain and liver effects of fumonisin B1 in BALB/c mice: implication of blood brain barrier. | 2005 | Food Chem. Toxicol. | pmid:15913876 |
Wang L et al. | OsLSD1, a rice zinc finger protein, regulates programmed cell death and callus differentiation. | 2005 | Mol. Plant Microbe Interact. | pmid:15915636 |
Fernández-Surumay G et al. | Fumonisin B-glucose reaction products are less toxic when fed to swine. | 2005 | J. Agric. Food Chem. | pmid:15884870 |
Paepens C et al. | Development of a liquid chromatography/tandem mass spectrometry method for the quantification of fumonisin B1, B2 and B3 in cornflakes. | 2005 | Rapid Commun. Mass Spectrom. | pmid:15973649 |
Halloy DJ et al. | Oral exposure to culture material extract containing fumonisins predisposes swine to the development of pneumonitis caused by Pasteurellamultocida. | 2005 | Toxicology | pmid:15979225 |
Osuchowski MF and Sharma RP | Fumonisin B1 induces necrotic cell death in BV-2 cells and murine cultured astrocytes and is antiproliferative in BV-2 cells while N2A cells and primary cortical neurons are resistant. | 2005 | Neurotoxicology | pmid:16005069 |
Javed T et al. | Comparative pathologic changes in broiler chicks on feed amended with Fusarium proliferatum culture material or purified fumonisin B1 and moniliformin. | 2005 | Mycopathologia | pmid:15983742 |
Stone JM et al. | Arabidopsis AtSPL14, a plant-specific SBP-domain transcription factor, participates in plant development and sensitivity to fumonisin B1. | 2005 | Plant J. | pmid:15703061 |
Sakamoto H et al. | Host sphingolipid biosynthesis as a target for hepatitis C virus therapy. | 2005 | Nat. Chem. Biol. | pmid:16408072 |
Bluhm BH and Woloshuk CP | Amylopectin induces fumonisin B1 production by Fusarium verticillioides during colonization of maize kernels. | 2005 | Mol. Plant Microbe Interact. | pmid:16478053 |
Sharma N et al. | Tumor necrosis factor alpha-mediated activation of c-Jun NH(2)-terminal kinase as a mechanism for fumonisin B(1) induced apoptosis in murine primary hepatocytes. | 2005 | J. Biochem. Mol. Toxicol. | pmid:16421893 |
Cvetnić Z et al. | Toxigenic potential of Fusarium species isolated from non-harvested maize. | 2005 | Arh Hig Rada Toksikol | pmid:16180614 |
Chivasa S et al. | Extracellular ATP functions as an endogenous external metabolite regulating plant cell viability. | 2005 | Plant Cell | pmid:16199612 |
Cetin Y and Bullerman LB | Cytotoxicity of Fusarium mycotoxins to mammalian cell cultures as determined by the MTT bioassay. | 2005 | Food Chem. Toxicol. | pmid:15778016 |
Kouadio JH et al. | Comparative study of cytotoxicity and oxidative stress induced by deoxynivalenol, zearalenone or fumonisin B1 in human intestinal cell line Caco-2. | 2005 | Toxicology | pmid:16019124 |
He Q et al. | Myriocin prevents fumonisin B1-induced sphingoid base accumulation in mice liver without ameliorating hepatotoxicity. | 2005 | Food Chem. Toxicol. | pmid:15811577 |
Soriano JM et al. | Mechanism of action of sphingolipids and their metabolites in the toxicity of fumonisin B1. | 2005 | Prog. Lipid Res. | pmid:16266752 |
Tani M et al. | Mechanisms of sphingosine and sphingosine 1-phosphate generation in human platelets. | 2005 | J. Lipid Res. | pmid:16061940 |
He Q and Sharma RP | Inhibition of tumor necrosis factor alpha signaling by anti-tumor necrosis factor alpha antibodies and pentoxifylline is unable to prevent fumonisin hepatotoxicity in mice. | 2005 | Toxicon | pmid:16054185 |
Petrache I et al. | Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice. | 2005 | Nat. Med. | pmid:15852018 |
Gelineau-van Waes J et al. | Maternal fumonisin exposure and risk for neural tube defects: mechanisms in an in vivo mouse model. | 2005 | Birth Defects Res. Part A Clin. Mol. Teratol. | pmid:15959874 |
Sharma RP et al. | Lupus-prone NZBWF1/J mice, defective in cytokine signaling, are resistant to fumonisin hepatotoxicity despite accumulation of liver sphinganine. | 2005 | Toxicology | pmid:16159691 |
He Q et al. | Fumonisin B1 hepatotoxicity in mice is attenuated by depletion of Kupffer cells by gadolinium chloride. | 2005 | Toxicology | pmid:15590129 |
Becker KP et al. | Selective inhibition of juxtanuclear translocation of protein kinase C betaII by a negative feedback mechanism involving ceramide formed from the salvage pathway. | 2005 | J. Biol. Chem. | pmid:15546881 |
Pepeljnjak S et al. | Toxic effects of Ustilago maydis and fumonisin B1 in rats. | 2005 | Acta Pharm | pmid:16375823 |
Deshmukh S et al. | Individual and combined effects of Fusarium moniliforme culture material, containing known levels of fumonisin B1, and Salmonella gallinarum infection on liver of Japanese quail. | 2005 | Avian Dis. | pmid:16405006 |
Cabassi E et al. | Intoxication with fumonisin B1 (FB1) in piglets and supplementation with granulated activated carbon: cellular-mediated immunoresponse. | 2005 | Vet. Res. Commun. | pmid:16244961 |
Caloni F et al. | In vitro study with Caco-2 cells on fumonisin B1: aminopentol intestinal passage and role of P-glycoprotein. | 2005 | Vet. Res. Commun. | pmid:16244976 |
Sánchez-Rangel D et al. | Fumonisin production by Fusarium verticillioides strains isolated from maize in Mexico and development of a polymerase chain reaction to detect potential toxigenic strains in grains. | 2005 | J. Agric. Food Chem. | pmid:16248554 |
Xia QZ et al. | [Spontaneous and induced programmed cell death in suspension cell cultures of cotton (Gossypium hirsutum L.)]. | 2005 | Shi Yan Sheng Wu Xue Bao | pmid:16231696 |
Cavaglieri L et al. | In vitro influence of bacterial mixtures on Fusarium verticillioides growth and fumonisin B1 production: effect of seeds treatment on maize root colonization. | 2005 | Lett. Appl. Microbiol. | pmid:16238641 |
Shephard GS et al. | Fumonisin mycotoxins in traditional Xhosa maize beer in South Africa. | 2005 | J. Agric. Food Chem. | pmid:16302789 |
Desjardins AE et al. | Identification and heritability of fumonisin insensitivity in Zea mays. | 2005 | Phytochemistry | pmid:16198380 |
Fornelli F et al. | Cytotoxicity induced by nivalenol, deoxynivalenol, and fumonisin B1 in the SF-9 insect cell line. | 2004 May-Jun | In Vitro Cell. Dev. Biol. Anim. | pmid:15479121 |
Foreman JH et al. | Neurologic abnormalities and cerebrospinal fluid changes in horses administered fumonisin B1 intravenously. | 2004 Mar-Apr | J. Vet. Intern. Med. | pmid:15058775 |
Yu MU et al. | Altered de novo sphingolipid biosynthesis is involved in the serum deprivation-induced cell death in LLC-PK1 cells. | 2004 | J. Toxicol. Environ. Health Part A | pmid:15513905 |
Yi F et al. | Homocysteine activates NADH/NADPH oxidase through ceramide-stimulated Rac GTPase activity in rat mesangial cells. | 2004 | Kidney Int. | pmid:15496169 |
Appierto V et al. | Involvement of c-Fos in fenretinide-induced apoptosis in human ovarian carcinoma cells. | 2004 | Cell Death Differ. | pmid:14647238 |
Sharma N et al. | Augmented fumonisin B1 toxicity in co-cultures: evidence for crosstalk between macrophages and non-parenchymatous liver epithelial cells involving proinflammatory cytokines. | 2004 | Toxicology | pmid:15363598 |
Stockmann-Juvala H et al. | Fumonisin B1-induced toxicity and oxidative damage in U-118MG glioblastoma cells. | 2004 | Toxicology | pmid:15337581 |
Aly SE et al. | Application of adsorbent agents technology in the removal of aflatoxin B(1) and fumonisin B(1) from malt extract. | 2004 | Food Chem. Toxicol. | pmid:15350680 |
Royer D et al. | Quantitative analysis of Fusarium mycotoxins in maize using accelerated solvent extraction before liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry. | 2004 | Food Addit Contam | pmid:15370841 |
Sharma N et al. | Sphingosine kinase activity confers resistance to apoptosis by fumonisin B1 in human embryonic kidney (HEK-293) cells. | 2004 | Chem. Biol. Interact. | pmid:15607760 |
Park JW et al. | Analysis of heat-processed corn foods for fumonisins and bound fumonisins. | 2004 | Food Addit Contam | pmid:15799562 |