fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Asthma D001249 52 associated lipids
Body Weight D001835 333 associated lipids
Brain Diseases D001927 27 associated lipids
Carcinoma D002277 18 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Choline Deficiency D002796 16 associated lipids
Cleft Palate D002972 9 associated lipids
Death, Sudden D003645 12 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Fatty Liver D005234 48 associated lipids
Fetal Resorption D005327 15 associated lipids
Gaucher Disease D005776 13 associated lipids
Glioblastoma D005909 27 associated lipids
Glioma D005910 112 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hydrocephalus D006849 6 associated lipids
Hyperplasia D006965 34 associated lipids
Inflammation D007249 119 associated lipids
Kidney Diseases D007674 29 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Magnesium Deficiency D008275 9 associated lipids
Mycoses D009181 18 associated lipids
Nervous System Diseases D009422 37 associated lipids
Neural Tube Defects D009436 5 associated lipids
Neuroblastoma D009447 66 associated lipids
Neuronal Ceroid-Lipofuscinoses D009472 5 associated lipids
Paralysis D010243 4 associated lipids
Pasteurella Infections D010326 8 associated lipids
Poultry Diseases D011201 21 associated lipids
Precancerous Conditions D011230 48 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Pseudorabies D011557 1 associated lipids
Pulmonary Edema D011654 23 associated lipids
Salmonella Infections, Animal D012481 9 associated lipids
Scrapie D012608 7 associated lipids
Seizures D012640 87 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Stomach Ulcer D013276 75 associated lipids
Stomatitis D013280 14 associated lipids
Swine Diseases D013553 16 associated lipids
Testicular Diseases D013733 15 associated lipids
Weight Gain D015430 101 associated lipids
Neuroectodermal Tumors, Primitive, Peripheral D018241 3 associated lipids
Adenoma, Liver Cell D018248 2 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

Download all related citations
Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
Mobio TA et al. Comparative study of the toxic effects of fumonisin B1 in rat C6 glioma cells and p53-null mouse embryo fibroblasts. 2003 Toxicology pmid:12504343
Williams LD et al. Leaching and binding of fumonisins in soil microcosms. 2003 J. Agric. Food Chem. pmid:12537442
Litvak DA et al. Modulators of ceramide metabolism sensitize colorectal cancer cells to chemotherapy: a novel treatment strategy. 2003 J. Gastrointest. Surg. pmid:12559195
Zhao H et al. Anoxia and reoxygenation of human endothelial cells decrease ceramide glucosyltransferase expression and activates caspases. 2003 FASEB J. pmid:12586734
Theumer MG et al. Immunobiological effects of AFB1 and AFB1-FB1 mixture in experimental subchronic mycotoxicoses in rats. 2003 Toxicology pmid:12604180
Maedler K et al. Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function. 2003 Diabetes pmid:12606514
Kim EK et al. Hidden fumonisin in corn flakes. 2003 Food Addit Contam pmid:12623665
Sharma RP et al. Deletion of IFN-gamma reduces fumonisin-induced hepatotoxicity in mice via alterations in inflammatory cytokines and apoptotic factors. 2003 J. Interferon Cytokine Res. pmid:12639295
Uchida Y et al. De novo ceramide synthesis participates in the ultraviolet B irradiation-induced apoptosis in undifferentiated cultured human keratinocytes. 2003 J. Invest. Dermatol. pmid:12648232
Camargos SM et al. Accumulation of fumonisins B1 and B2 in freshly harvested Brazilian commercial maize at three locations during two nonconsecutive seasons. 2002 Mycopathologia pmid:12650599
Kritzinger Q et al. Mycoflora and fumonisin mycotoxins associated with cowpea [Vigna unguiculata (L.) Walp] seeds. 2003 J. Agric. Food Chem. pmid:12670154
Koyanagi S et al. Elevation of de novo ceramide synthesis in tumor masses and the role of microsomal dihydroceramide synthase. 2003 Int. J. Cancer pmid:12672022
Gopee NV and Sharma RP Sphingoid bases and their phosphates: transient activation and delayed repression of protein kinase C isoforms and their possible involvement in fumonisin B1 cytotoxicity. 2003 Toxicology pmid:12699912
Guo Y et al. [Preparation and identification of anti-fumonisin B1 monoclonal antibody]. 1999 Wei Sheng Yan Jiu pmid:12712702
Hering H et al. Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability. 2003 J. Neurosci. pmid:12716933
Wang H and Zhang X [Recent progress in the study of common fusarium mycotoxins on apoptosis of cells]. 2000 Wei Sheng Yan Jiu pmid:12725071
Johnson VJ et al. Increased susceptibility of renal epithelial cells to TNFalpha-induced apoptosis following treatment with fumonisin B1. 2003 Chem. Biol. Interact. pmid:12732456
Pepeljnjak S et al. Screening toxicity study in young carp (Cyprinus carpio L.) on feed amended with fumonisin B1. 2003 Mycopathologia pmid:12733635
Tornyos G et al. Effect of dietary fumonisin B1 on certain immune parameters of weaned pigs. 2003 Acta Vet. Hung. pmid:12737044
Okino N et al. The reverse activity of human acid ceramidase. 2003 J. Biol. Chem. pmid:12764132