fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Luongo D et al. | Interactive effects of fumonisin B1 and alpha-zearalenol on proliferation and cytokine expression in Jurkat T cells. | 2006 | Toxicol In Vitro | pmid:16899350 |
Minervini F et al. | Toxic effects induced by mycotoxin fumonisin B1 on equine spermatozoa: assessment of viability, sperm chromatin structure stability, ROS production and motility. | 2010 | Toxicol In Vitro | pmid:20541003 |
Bernabucci U et al. | Aflatoxin B1 and fumonisin B1 affect the oxidative status of bovine peripheral blood mononuclear cells. | 2011 | Toxicol In Vitro | pmid:21256206 |
Minervini F et al. | Toxicity and apoptosis induced by the mycotoxins nivalenol, deoxynivalenol and fumonisin B1 in a human erythroleukemia cell line. | 2004 | Toxicol In Vitro | pmid:14630058 |
Sancak D and Ozden S | Global histone modifications in Fumonisin B1 exposure in rat kidney epithelial cells. | 2015 | Toxicol In Vitro | pmid:26208285 |
Pósa R et al. | A comparative pathological finding in pigs exposed to fumonisin B1 and/or Mycoplasma hyopneumoniae. | 2016 | Toxicol Ind Health | pmid:25107460 |
Hard GC et al. | Rat kidney pathology induced by chronic exposure to fumonisin B1 includes rare variants of renal tubule tumor. | 2001 May-Jun | Toxicol Pathol | pmid:11442024 |
Bucci TJ et al. | Renal effects of fumonisin mycotoxins in animals. | 1998 Jan-Feb | Toxicol Pathol | pmid:9502399 |
Gumprecht LA et al. | Development of fumonisin-induced hepatotoxicity and pulmonary edema in orally dosed swine: morphological and biochemical alterations. | 1998 Nov-Dec | Toxicol Pathol | pmid:9864095 |
He Q et al. | Fumonisin-induced tumor necrosis factor-alpha expression in a porcine kidney cell line is independent of sphingoid base accumulation induced by ceramide synthase inhibition. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11437650 |
Liu BH et al. | The effects of mycotoxins, fumonisin B1 and aflatoxin B1, on primary swine alveolar macrophages. | 2002 | Toxicol. Appl. Pharmacol. | pmid:12009859 |
Ramasamy S et al. | Fumonisin B1 alters sphingolipid metabolism and disrupts the barrier function of endothelial cells in culture. | 1995 | Toxicol. Appl. Pharmacol. | pmid:7645031 |
Cai Q et al. | Validation of fumonisin biomarkers in F344 rats. | 2007 | Toxicol. Appl. Pharmacol. | pmid:17904604 |
Constable PD et al. | Ingestion of fumonisin B1-containing culture material decreases cardiac contractility and mechanical efficiency in swine. | 2000 | Toxicol. Appl. Pharmacol. | pmid:10652243 |
Mobio TA et al. | Epigenetic properties of fumonisin B(1): cell cycle arrest and DNA base modification in C6 glioma cells. | 2000 | Toxicol. Appl. Pharmacol. | pmid:10739748 |
Suzuki CA et al. | The effects of fumonisin B1 on several markers of nephrotoxicity in rats. | 1995 | Toxicol. Appl. Pharmacol. | pmid:7645015 |
Schmelz EM et al. | Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases. | 1998 | Toxicol. Appl. Pharmacol. | pmid:9473533 |
Norred WP et al. | Mycotoxin-induced elevation of free sphingoid bases in precision-cut rat liver slices: specificity of the response and structure-activity relationships. | 1997 | Toxicol. Appl. Pharmacol. | pmid:9356308 |
Yoo HS et al. | Elevated sphingoid bases and complex sphingolipid depletion as contributing factors in fumonisin-induced cytotoxicity. | 1996 | Toxicol. Appl. Pharmacol. | pmid:8658522 |
Kim MS et al. | Fumonisin B(1) induces apoptosis in LLC-PK(1) renal epithelial cells via a sphinganine- and calmodulin-dependent pathway. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11601888 |