fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Schumacher J et al. | An investigation of the role of Fusarium moniliforme in duodenitis/proximal jejunitis of horses. | 1995 | Vet Hum Toxicol | pmid:7709589 |
Lebepe-Mazur S et al. | Fusarium proliferatum-fermented corn stimulates development of placental glutathione S-transferase-positive altered hepatic foci in female rats. | 1995 | Vet Hum Toxicol | pmid:7709594 |
Huang C et al. | Repression of protein kinase C and stimulation of cyclic AMP response elements by fumonisin, a fungal encoded toxin which is a carcinogen. | 1995 | Cancer Res. | pmid:7712470 |
Voss KA et al. | Subchronic feeding study of the mycotoxin fumonisin B1 in B6C3F1 mice and Fischer 344 rats. | 1995 | Fundam Appl Toxicol | pmid:7713333 |
Kubena LF et al. | Influence of fumonisin B1, present in Fusarium moniliforme culture material, and T-2 toxin on turkey poults. | 1995 | Poult. Sci. | pmid:7724453 |
Schwarz A et al. | A regulatory role for sphingolipids in neuronal growth. Inhibition of sphingolipid synthesis and degradation have opposite effects on axonal branching. | 1995 | J. Biol. Chem. | pmid:7738041 |
Sofer A and Futerman AH | Cationic amphiphilic drugs inhibit the internalization of cholera toxin to the Golgi apparatus and the subsequent elevation of cyclic AMP. | 1995 | J. Biol. Chem. | pmid:7744860 |
Ritieni A et al. | Isolation and characterization of fusaproliferin, a new toxic metabolite from Fusarium proliferatum. | 1995 | Nat. Toxins | pmid:7749578 |
Trucksess MW et al. | Immunoaffinity column coupled with liquid chromatography for determination of fumonisin B1 in canned and frozen sweet corn. | 1995 May-Jun | J AOAC Int | pmid:7756885 |
Wilkes JG et al. | Determination of fumonisins B1, B2, B3 and B4 by high-performance liquid chromatography with evaporative light-scattering detection. | 1995 | J Chromatogr A | pmid:7757206 |
Scott PM et al. | Fermentation of wort containing added ochratoxin A and fumonisins B1 and B2. | 1995 Jan-Feb | Food Addit Contam | pmid:7758629 |
Fukuda S et al. | Preparation and characterization of anti-fumonisin monoclonal antibodies. | 1994 | Biosci. Biotechnol. Biochem. | pmid:7764867 |
Chatterjee D et al. | Nuclear disintegration in chicken peritoneal macrophages exposed to fumonisin B1 from Indian maize. | 1995 | Lett. Appl. Microbiol. | pmid:7766078 |
Cahagnier B et al. | Growth of Fusarium moniliforme and its biosynthesis of fumonisin B1 on maize grain as a function of different water activities. | 1995 | Lett. Appl. Microbiol. | pmid:7766121 |
Beier RC et al. | Calculated three dimensional structures of the fumonisin B1-4 mycotoxins. | 1995 | Bull Environ Contam Toxicol | pmid:7767023 |
Wu WI et al. | Regulation of lipid biosynthesis in Saccharomyces cerevisiae by fumonisin B1. | 1995 | J. Biol. Chem. | pmid:7768913 |
Strum JC et al. | Ceramide triggers meiotic cell cycle progression in Xenopus oocytes. A potential mediator of progesterone-induced maturation. | 1995 | J. Biol. Chem. | pmid:7768956 |
Merrill AH et al. | Sphingolipid biosynthesis de novo by rat hepatocytes in culture. Ceramide and sphingomyelin are associated with, but not required for, very low density lipoprotein secretion. | 1995 | J. Biol. Chem. | pmid:7775441 |
Gross SM et al. | Developmental effects of fumonisin B1-containing Fusarium moniliforme culture extract in CD1 mice. | 1994 | Mycopathologia | pmid:7777035 |
Martynova EA et al. | [Modulation of the level of sphingomyelin cycle products and expression of the CD3 receptor in immunocompetent organs by fumonisin B1]. | 1995 | Biokhimiia | pmid:7779984 |
Merrill AH et al. | Role of dietary sphingolipids and inhibitors of sphingolipid metabolism in cancer and other diseases. | 1995 | J. Nutr. | pmid:7782925 |
Weibking TS et al. | Individual and combined effects of feeding Fusarium moniliforme culture material, containing known levels of fumonisin B1, and aflatoxin B1 in the young turkey poult. | 1994 | Poult. Sci. | pmid:7816726 |
Palyusik M and Moran EM | Porcine pulmonary edema with hydrothorax: a review. | 1994 | J. Environ. Pathol. Toxicol. Oncol. | pmid:7823296 |
Espada Y et al. | Fumonisin mycotoxicosis in broilers. Weights and serum chemistry modifications. | 1994 Jul-Sep | Avian Dis. | pmid:7832697 |
Casteel SW et al. | Chronic effects of dietary fumonisin on the heart and pulmonary vasculature of swine. | 1994 | Fundam Appl Toxicol | pmid:7867903 |
Desjardins AE et al. | Genetic analysis of fumonisin production and virulence of Gibberella fujikuroi mating population A (Fusarium moniliforme) on maize (Zea mays) seedlings. | 1995 | Appl. Environ. Microbiol. | pmid:7887628 |
Diaz GJ and Boermans HJ | Fumonisin toxicosis in domestic animals: a review. | 1994 | Vet Hum Toxicol | pmid:7900277 |
Shephard GS et al. | Distribution and excretion of a single dose of the mycotoxin fumonisin B1 in a non-human primate. | 1994 | Toxicon | pmid:7940579 |
Maragos CM and Richard JL | Quantitation and stability of fumonisins B1 and B2 in milk. | 1994 Sep-Oct | J AOAC Int | pmid:7950418 |
Visconti A et al. | Stability of fumonisins (FB1 and FB2) in solution. | 1994 Jul-Aug | Food Addit Contam | pmid:7958112 |
Doko MB and Visconti A | Occurrence of fumonisins B1 and B2 in corn and corn-based human foodstuffs in Italy. | 1994 Jul-Aug | Food Addit Contam | pmid:7958113 |
Branham BE and Plattner RD | Alanine is a precursor in the biosynthesis of fumonisin B1 by Fusarium moniliforme. | 1993 | Mycopathologia | pmid:8008046 |
Brown DW et al. | Experimental feeding of Fusarium moniliforme culture material containing fumonisin B1 to channel catfish, Ictalurus punctatus. | 1994 | J. Vet. Diagn. Invest. | pmid:8011771 |
Yoshizawa T et al. | Fumonisin occurrence in corn from high- and low-risk areas for human esophageal cancer in China. | 1994 | Appl. Environ. Microbiol. | pmid:8017941 |
Cawood ME et al. | Interaction of 14C-labelled fumonisin B mycotoxins with primary rat hepatocyte cultures. | 1994 | Food Chem. Toxicol. | pmid:8045475 |
Motelin GK et al. | Temporal and dose-response features in swine fed corn screenings contaminated with fumonisin mycotoxins. | 1994 | Mycopathologia | pmid:8052290 |
Prelusky DB et al. | Pharmacokinetic fate of 14C-labelled fumonisin B1 in swine. | 1994 | Nat. Toxins | pmid:8075896 |
Vudathala DK et al. | Pharmacokinetic fate and pathological effects of 14C-fumonisin B1 in laying hens. | 1994 | Nat. Toxins | pmid:8075897 |
Scott PM et al. | Determination of fumonisins in milk. | 1994 | J Environ Sci Health B | pmid:8089434 |
Wolf G | Mechanism of the mitogenic and carcinogenic action of fumonisin B1, a mycotoxin. | 1994 | Nutr. Rev. | pmid:8090377 |
Schroeder JJ et al. | Disruption of sphingolipid metabolism and stimulation of DNA synthesis by fumonisin B1. A molecular mechanism for carcinogenesis associated with Fusarium moniliforme. | 1994 | J. Biol. Chem. | pmid:8106389 |
Shephard GS et al. | Determination of the mycotoxin fumonisin B1 and identification of its partially hydrolysed metabolites in the faeces of non-human primates. | 1994 | Food Chem. Toxicol. | pmid:8132161 |
Riley RT et al. | Dietary fumonisin B1 induces disruption of sphingolipid metabolism in Sprague-Dawley rats: a new mechanism of nephrotoxicity. | 1994 | J. Nutr. | pmid:8145083 |
Floss JL et al. | Developmental toxicity in hamsters of an aqueous extract of Fusarium moniliforme culture material containing known quantities of fumonisin B1. | 1994 | Vet Hum Toxicol | pmid:8154103 |
Dombrink-Kurtzman MA et al. | Lymphocyte cytotoxicity and erythrocytic abnormalities induced in broiler chicks by fumonisins B1 and B2 and moniliformin from Fusarium proliferatum. | 1993 | Mycopathologia | pmid:8159217 |
Chu FS and Li GY | Simultaneous occurrence of fumonisin B1 and other mycotoxins in moldy corn collected from the People's Republic of China in regions with high incidences of esophageal cancer. | 1994 | Appl. Environ. Microbiol. | pmid:8161178 |
Voss KA et al. | A preliminary investigation on renal and hepatic toxicity in rats fed purified fumonisin B1. | 1993 | Nat. Toxins | pmid:8167938 |
Norred WP et al. | Distribution and excretion of [14C]fumonisin B1 in male Sprague-Dawley rats. | 1993 | Nat. Toxins | pmid:8167955 |
Plumlee KH and Galey FD | Neurotoxic mycotoxins: a review of fungal toxins that cause neurological disease in large animals. | 1994 Jan-Feb | J. Vet. Intern. Med. | pmid:8176663 |
Dombrink-Kurtzman MA et al. | An optimized MTT bioassay for determination of cytotoxicity of fumonisins in turkey lymphocytes. | 1994 Mar-Apr | J AOAC Int | pmid:8199486 |
Scott PM and Lawrence GA | Stability and problems in recovery of fumonisins added to corn-based foods. | 1994 Mar-Apr | J AOAC Int | pmid:8199487 |
Visconti A and Doko MB | Survey of fumonisin production by Fusarium isolated from cereals in Europe. | 1994 Mar-Apr | J AOAC Int | pmid:8199488 |
Shephard GS et al. | Biliary excretion of the mycotoxin fumonisin B1 in rats. | 1994 | Food Chem. Toxicol. | pmid:8206448 |
Christley RM et al. | Leukoencephalomalacia in horses. | 1993 | Aust. Vet. J. | pmid:8216085 |
Merrill AH et al. | Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ. | 1993 | J. Biol. Chem. | pmid:8262970 |
Chamberlain WJ et al. | Levels of fumonisin B1 in corn naturally contaminated with aflatoxins. | 1993 | Food Chem. Toxicol. | pmid:8282284 |
Javed T et al. | Mortality in broiler chicks on feed amended with Fusarium proliferatum culture material or with purified fumonisin B1 and moniliformin. | 1993 | Mycopathologia | pmid:8302366 |
Javed T et al. | Embryopathic and embryocidal effects of purified fumonisin B1 or Fusarium proliferatum culture material extract on chicken embryos. | 1993 | Mycopathologia | pmid:8302367 |
Gelderblom WC et al. | Fumonisin B1 dosimetry in relation to cancer initiation in rat liver. | 1994 | Carcinogenesis | pmid:8313510 |
Harel R and Futerman AH | Inhibition of sphingolipid synthesis affects axonal outgrowth in cultured hippocampal neurons. | 1993 | J. Biol. Chem. | pmid:8314804 |
Kaneshiro T et al. | 2-Hydroxyhexadecanoic and 8,9,13-trihydroxydocosanoic acid accumulation by yeasts treated with fumonisin B1. | 1993 | Lipids | pmid:8316046 |
Scott PM | Fumonisins. | 1993 | Int. J. Food Microbiol. | pmid:8347425 |
Grimes JL et al. | Paralysis of undetermined origin in bobwhite quail. | 1993 Apr-Jun | Avian Dis. | pmid:8363521 |
Alberts JF et al. | Production of [14C]fumonisin B1 by Fusarium moniliforme MRC 826 in corn cultures. | 1993 | Appl. Environ. Microbiol. | pmid:8368853 |
Kamps-Holtzapple C et al. | Analysis of hapten-carrier protein conjugates by nondenaturing gel electrophoresis. | 1993 | J. Immunol. Methods | pmid:8370930 |
Casteel SW et al. | Chronic toxicity of fumonisin in weanling pigs. | 1993 | J. Vet. Diagn. Invest. | pmid:8373857 |
Price WD et al. | Naturally occurring toxins in feedstuffs: Center for Veterinary Medicine Perspective. | 1993 | J. Anim. Sci. | pmid:8407668 |
Toxins derived from Fusarium moniliforme: fumonisins B1 and B2 and fusarin C. | 1993 | IARC Monogr Eval Carcinog Risks Hum | pmid:8411627 | |
Riley RT et al. | Alteration of tissue and serum sphinganine to sphingosine ratio: an early biomarker of exposure to fumonisin-containing feeds in pigs. | 1993 | Toxicol. Appl. Pharmacol. | pmid:8430417 |
Coulombe RA | Biological action of mycotoxins. | 1993 | J. Dairy Sci. | pmid:8463495 |
Weibking TS et al. | Effects of feeding Fusarium moniliforme culture material, containing known levels of fumonisin B1, on the young broiler chick. | 1993 | Poult. Sci. | pmid:8464788 |
Ross PF et al. | Experimental equine leukoencephalomalacia, toxic hepatosis, and encephalopathy caused by corn naturally contaminated with fumonisins. | 1993 | J. Vet. Diagn. Invest. | pmid:8466984 |
Weibking TS et al. | Fumonisin toxicity in turkey poults. | 1993 | J. Vet. Diagn. Invest. | pmid:8466985 |
Abbas HK et al. | Biological activities of fumonisins, mycotoxins from Fusarium moniliforme, in jimsonweed (Datura stramonium L.) and mammalian cell cultures. | 1993 | Toxicon | pmid:8470138 |
Colvin BM et al. | Fumonisin toxicosis in swine: clinical and pathologic findings. | 1993 | J. Vet. Diagn. Invest. | pmid:8507702 |
Gelderblom WC et al. | Structure-activity relationships of fumonisins in short-term carcinogenesis and cytotoxicity assays. | 1993 | Food Chem. Toxicol. | pmid:8514212 |
Yamashita A et al. | Fusarium mycotoxins (fumonisins, nivalenol, and zearalenone) and aflatoxins in corn from Southeast Asia. | 1995 | Biosci. Biotechnol. Biochem. | pmid:8520126 |
Sanchis V et al. | Fumonisins B1 and B2 and toxigenic Fusarium strains in feeds from the Spanish market. | 1995 | Int. J. Food Microbiol. | pmid:8527327 |
Moretti A et al. | Fertility of Fusarium moniliforme from maize and sorghum related to fumonisin production in Italy. | 1995 | Mycopathologia | pmid:8532049 |
Qureshi MA et al. | Fusarium proliferatum culture material alters several production and immune performance parameters in White Leghorn chickens. | 1995 | Immunopharmacol Immunotoxicol | pmid:8537614 |
Inooka S and Toyokuni T | Sphingosine transfer in cell-to-cell interaction. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8579607 |
Javed T et al. | Serohematologic alterations in broiler chicks on feed amended with Fusarium proliferatum culture material on fumonisin B1 and moniliformin. | 1995 | J. Vet. Diagn. Invest. | pmid:8580176 |
Prelusky DB et al. | Pilot study on the plasma pharmacokinetics of fumonisin B1 in cows following a single dose by oral gavage or intravenous administration. | 1995 | Nat. Toxins | pmid:8581325 |
Gumprecht LA et al. | Effects of intravenous fumonisin B1 in rabbits: nephrotoxicity and sphingolipid alterations. | 1995 | Nat. Toxins | pmid:8581326 |
Abbas HK et al. | Biological activities of synthetic analogues of Alternaria alternata toxin (AAL-toxin) and fumonisin in plant and mammalian cell cultures. | 1995 | Phytochemistry | pmid:8590636 |
Steyn PS | Mycotoxins, general view, chemistry and structure. | 1995 | Toxicol. Lett. | pmid:8597152 |
Kuiper-Goodman T | Mycotoxins: risk assessment and legislation. | 1995 | Toxicol. Lett. | pmid:8597153 |
Harvey RB et al. | Influence of aflatoxin and fumonisin B1-containing culture material on growing barrows. | 1995 | Am. J. Vet. Res. | pmid:8599531 |
Fukuda H et al. | Inhibition of protein serine/threonine phosphatases by fumonisin B1, a mycotoxin. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8602837 |
Wang W et al. | Fumonisins and Alternaria alternata lycopersici toxins: sphinganine analog mycotoxins induce apoptosis in monkey kidney cells. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8622958 |
Tolleson WH et al. | Apoptotic and anti-proliferative effects of fumonisin B1 in human keratinocytes, fibroblasts, esophageal epithelial cells and hepatoma cells. | 1996 | Carcinogenesis | pmid:8625445 |
Jarvis WD et al. | Induction of apoptosis and potentiation of ceramide-mediated cytotoxicity by sphingoid bases in human myeloid leukemia cells. | 1996 | J. Biol. Chem. | pmid:8626522 |
Shephard GS et al. | Worldwide survey of fumonisin contamination of corn and corn-based products. | 1996 May-Jun | J AOAC Int | pmid:8634537 |
Sydenham EW et al. | Liquid chromatographic determination of fumonisins B1, B2, and B3 in corn: AOAC-IUPAC Collaborative Study. | 1996 May-Jun | J AOAC Int | pmid:8634538 |
Gelderblom WC et al. | Effect of fumonisin B1 on protein and lipid synthesis in primary rat hepatocytes. | 1996 | Food Chem. Toxicol. | pmid:8641662 |
Maragos CM et al. | Determination of hydrolysed fumonisin B1 (HFB1) in corn by competitive direct enzyme-linked immunosorbent assay. | 1996 | Food Addit Contam | pmid:8647300 |
Yoo HS et al. | Elevated sphingoid bases and complex sphingolipid depletion as contributing factors in fumonisin-induced cytotoxicity. | 1996 | Toxicol. Appl. Pharmacol. | pmid:8658522 |
Hidari KIPJ S et al. | Complete removal of sphingolipids from the plasma membrane disrupts cell to substratum adhesion of mouse melanoma cells. | 1996 | J. Biol. Chem. | pmid:8662871 |
Jaffrézou JP et al. | Daunorubicin-induced apoptosis: triggering of ceramide generation through sphingomyelin hydrolysis. | 1996 | EMBO J. | pmid:8665849 |
ApSimon JW and Miller JD | Fumonisin generation. | 1996 | Nat. Toxins | pmid:8680748 |