fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Mehta R et al. | Glutathione S-transferase-placental form expression and proliferation of hepatocytes in fumonisin B1-treated male and female Sprague-Dawley rats. | 1998 | Cancer Lett. | pmid:9652790 |
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DiPietrantonio AM et al. | Regulation of G1/S transition and induction of apoptosis in HL-60 leukemia cells by fenretinide (4HPR). | 1998 | Int. J. Cancer | pmid:9724094 |
Gamen S et al. | Caspases are the main executioners of Fas-mediated apoptosis, irrespective of the ceramide signalling pathway. | 1998 | Cell Death Differ. | pmid:10200470 |
Voss KA et al. | In vivo effects of fumonisin B1-producing and fumonisin B1-nonproducing Fusarium moniliforme isolates are similar: fumonisins B2 and B3 cause hepato- and nephrotoxicity in rats. | 1998 | Mycopathologia | pmid:9725030 |
Ali-Vehmas T et al. | Measurement of antibacterial activities of T-2 toxin, deoxynivalenol, ochratoxin A, aflatoxin B1 and fumonisin B1 using microtitration tray-based turbidimetric techniques. | 1998 | Zentralbl Veterinarmed A | pmid:9838857 |
Gurung NK et al. | Effects of fumonisin B1-contaminated feeds on weanling angora goats. | 1998 | J. Anim. Sci. | pmid:9856397 |
Auzenne E et al. | Cytotoxic effects of sphingolipids as single or multi-modality agents on human melanoma and soft tissue sarcoma in vitro. | 1998 | Melanoma Res. | pmid:9664144 |
Tsunoda M et al. | Early fumonisin B1 toxicity in relation to disrupted sphingolipid metabolism in male BALB/c mice. | 1998 | J. Biochem. Mol. Toxicol. | pmid:9664234 |
Humpf HU et al. | Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor. | 1998 | J. Biol. Chem. | pmid:9668088 |
Abel S and Gelderblom WC | Oxidative damage and fumonisin B1-induced toxicity in primary rat hepatocytes and rat liver in vivo. | 1998 | Toxicology | pmid:9928627 |
van der Westhuizen L et al. | Inhibition of sphingolipid biosynthesis in rat primary hepatocyte cultures by fumonisin B1 and other structurally related compounds. | 1998 | Food Chem. Toxicol. | pmid:9674957 |
Kutuzov MA et al. | Expression and characterization of PP7, a novel plant protein Ser/Thr phosphatase distantly related to RdgC/PPEF and PP5. | 1998 | FEBS Lett. | pmid:9862444 |
Munkvold G et al. | Occurrence of fusaproliferin and beauvericin in Fusarium-contaminated livestock feed in Iowa. | 1998 | Appl. Environ. Microbiol. | pmid:9758820 |
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de Nijs M et al. | Assessment of human exposure to fumonisin B1. | 1998 | J. Food Prot. | pmid:9678173 |
Tsunoda M et al. | Fumonisin B1-induced increases in neurotransmitter metabolite levels in different brain regions of BALB/c mice. | 1998 | Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. | pmid:9827064 |
Bucci TJ et al. | Renal effects of fumonisin mycotoxins in animals. | 1998 Jan-Feb | Toxicol Pathol | pmid:9502399 |
Stack ME | Analysis of fumonisin B1 and its hydrolysis product in tortillas. | 1998 Jul-Aug | J AOAC Int | pmid:9680698 |
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de Nijs M et al. | The occurrence of fumonisin B1 in maize-containing foods in The Netherlands. | 1998 May-Jun | Food Addit Contam | pmid:9764206 |
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Wang ZG et al. | Dimorphic fungus characteristic of fumonisin-producing strains of Fusarium moniliforme from Zhejiang. | 1998-1999 | Mycopathologia | pmid:10531682 |
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Kedera CJ et al. | Incidence of Fusarium spp. and levels of fumonisin B1 in maize in western Kenya. | 1999 | Appl. Environ. Microbiol. | pmid:9872757 |
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Pelagalli A et al. | The mycotoxin fumonisin B1 inhibits integrin-mediated cell-matrix adhesion. | 1999 | Biochimie | pmid:10575354 |
Lemmer ER et al. | Histopathology and gene expression changes in rat liver during feeding of fumonisin B1, a carcinogenic mycotoxin produced by Fusarium moniliforme. | 1999 | Carcinogenesis | pmid:10334199 |
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Abbas HK et al. | Fumonisin B1 from the fungus Fusarium moniliforme causes contact toxicity in plants: evidence from studies with biosynthetically labeled toxin. | 1999 | J Nat Toxins | pmid:10591043 |
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Wang E et al. | Fumonisin B1 consumption by rats causes reversible, dose-dependent increases in urinary sphinganine and sphingosine. | 1999 | J. Nutr. | pmid:9915902 |
Meredith FI et al. | Fumonisin B1 and hydrolyzed fumonisin B1 (AP1) in tortillas and nixtamalized corn (Zea mays L.) from two different geographic locations in Guatemala. | 1999 | J. Food Prot. | pmid:10528731 |
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Spinedi A et al. | Ceramide accumulation precedes caspase-dependent apoptosis in CHP-100 neuroepithelioma cells exposed to the protein phosphatase inhibitor okadaic acid. | 1999 | Cell Death Differ. | pmid:10453072 |
Williamson LC et al. | Neuronal sensitivity to tetanus toxin requires gangliosides. | 1999 | J. Biol. Chem. | pmid:10455200 |
Warfield CY and Gilchrist DG | Influence of kernel age on fumonisin B1 production in maize by Fusarium moniliforme. | 1999 | Appl. Environ. Microbiol. | pmid:10388675 |
Liao WC et al. | Ataxia telangiectasia-mutated gene product inhibits DNA damage-induced apoptosis via ceramide synthase. | 1999 | J. Biol. Chem. | pmid:10364237 |
Abbas HK et al. | Mycotoxin production by Fusarium proliferatum isolates from rice with Fusarium sheath rot disease. | 1999 | Mycopathologia | pmid:10967968 |
Tolleson WH et al. | Fumonisin B1 induces apoptosis in cultured human keratinocytes through sphinganine accumulation and ceramide depletion. | 1999 | Int. J. Oncol. | pmid:10200332 |
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