fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Inflammation D007249 119 associated lipids
Fatty Liver D005234 48 associated lipids
Body Weight D001835 333 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Precancerous Conditions D011230 48 associated lipids
Carcinoma D002277 18 associated lipids
Pulmonary Edema D011654 23 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Testicular Diseases D013733 15 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Asthma D001249 52 associated lipids
Kidney Diseases D007674 29 associated lipids
Weight Gain D015430 101 associated lipids
Brain Diseases D001927 27 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Hyperplasia D006965 34 associated lipids
Magnesium Deficiency D008275 9 associated lipids
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Nervous System Diseases D009422 37 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Seizures D012640 87 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Death, Sudden D003645 12 associated lipids
Gaucher Disease D005776 13 associated lipids
Adenoma D000236 40 associated lipids
Pasteurella Infections D010326 8 associated lipids
Swine Diseases D013553 16 associated lipids
Poultry Diseases D011201 21 associated lipids
Hydrocephalus D006849 6 associated lipids
Glioblastoma D005909 27 associated lipids
Neuronal Ceroid-Lipofuscinoses D009472 5 associated lipids
Salmonella Infections, Animal D012481 9 associated lipids
Paralysis D010243 4 associated lipids
Neural Tube Defects D009436 5 associated lipids
Fetal Resorption D005327 15 associated lipids
Cleft Palate D002972 9 associated lipids
Choline Deficiency D002796 16 associated lipids
Stomatitis D013280 14 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Mycoses D009181 18 associated lipids
Adenoma, Liver Cell D018248 2 associated lipids
Scrapie D012608 7 associated lipids
Neuroectodermal Tumors, Primitive, Peripheral D018241 3 associated lipids
Pseudorabies D011557 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

Download all related citations
Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
Cirlini M et al. Are Treated Celiac Patients at Risk for Mycotoxins? An Italian Case-Study. 2016 Toxins (Basel) pmid:28036017
Luttgeharm KD et al. Substrate specificity, kinetic properties and inhibition by fumonisin B1 of ceramide synthase isoforms from Arabidopsis. 2016 Biochem. J. pmid:26635357
Shaheen HM et al. The ceramide inhibitor fumonisin B1 mitigates the pulmonary effects of low-dose diesel exhaust inhalation in mice. 2016 Ecotoxicol. Environ. Saf. pmid:27376354
Fernández-Blanco C et al. An in vitro investigation on the cytotoxic and nuclear receptor transcriptional activity of the mycotoxins fumonisin B1 and beauvericin. 2016 Toxicol. Lett. pmid:27234500
Romero A et al. Mycotoxins modify the barrier function of Caco-2 cells through differential gene expression of specific claudin isoforms: Protective effect of illite mineral clay. 2016 Toxicology pmid:27153755
Yin S et al. Fumonisin B1 induces autophagic cell death via activation of ERN1-MAPK8/9/10 pathway in monkey kidney MARC-145 cells. 2016 Arch. Toxicol. pmid:25925693
Szabó A et al. Acute hepatic effects of low-dose fumonisin B(1) in rats. 2016 Acta Vet. Hung. pmid:27993098
Savi GD et al. Fumonisins B1 and B2 in the corn-milling process and corn-based products, and evaluation of estimated daily intake. 2016 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:26605670
Fumero MV et al. Ecophysiology of Fusarium temperatum isolated from maize in Argentina. 2016 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:26535974
Falavigna C et al. Oleoyl and linoleoyl esters of fumonisin B1 are differently produced by Fusarium verticillioides on maize and rice based media. 2016 Int. J. Food Microbiol. pmid:26492388
Ren W et al. Urchin-like gold nanoparticle-based immunochromatographic strip test for rapid detection of fumonisin B1 in grains. 2015 Anal Bioanal Chem pmid:26297453
Luttgeharm KD et al. Overexpression of Arabidopsis Ceramide Synthases Differentially Affects Growth, Sphingolipid Metabolism, Programmed Cell Death, and Mycotoxin Resistance. 2015 Plant Physiol. pmid:26276842
Zhao Y et al. Classic myrosinase-dependent degradation of indole glucosinolate attenuates fumonisin B1-induced programmed cell death in Arabidopsis. 2015 Plant J. pmid:25645692
Boppana NB et al. C6-pyridinium ceramide sensitizes SCC17B human head and neck squamous cell carcinoma cells to photodynamic therapy. 2015 J. Photochem. Photobiol. B, Biol. pmid:25635908
Jebali A et al. Modification of nanocellulose by poly-lysine can inhibit the effect of fumonisin B1 on mouse liver cells. 2015 Colloids Surf B Biointerfaces pmid:25601749
Hahn I et al. Effects of orally administered fumonisin B₁ (FB₁), partially hydrolysed FB₁, hydrolysed FB₁ and N-(1-deoxy-D-fructos-1-yl) FB₁ on the sphingolipid metabolism in rats. 2015 Food Chem. Toxicol. pmid:25475052
Clarke R et al. High content analysis: a sensitive tool to detect and quantify the cytotoxic, synergistic and antagonistic effects of chemical contaminants in foods. 2015 Toxicol. Lett. pmid:25623391
Sun LH et al. Individual and combined cytotoxic effects of aflatoxin B1, zearalenone, deoxynivalenol and fumonisin B1 on BRL 3A rat liver cells. 2015 Toxicon pmid:25549941
Riley RT et al. Evidence for fumonisin inhibition of ceramide synthase in humans consuming maize-based foods and living in high exposure communities in Guatemala. 2015 Mol Nutr Food Res pmid:26264677
Hernández-Corbacho MJ et al. Tumor Necrosis Factor-α (TNFα)-induced Ceramide Generation via Ceramide Synthases Regulates Loss of Focal Adhesion Kinase (FAK) and Programmed Cell Death. 2015 J. Biol. Chem. pmid:26318452