fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Scudamore KA et al. | Determination of mycotoxins in pet foods sold for domestic pets and wild birds using linked-column immunoassay clean-up and HPLC. | 1997 Feb-Mar | Food Addit Contam | pmid:9102350 |
Voss KA et al. | Subchronic toxicity of fumonisin B1 to male and female rats. | 1995 May-Jun | Food Addit Contam | pmid:7664945 |
MarÃn S et al. | Control of growth and fumonisin B1 production by Fusarium verticillioides and Fusarium proliferatum isolates in moist maize with propionate preservatives. | 1999 | Food Addit Contam | pmid:10789377 |
Maragos CM et al. | Determination of hydrolysed fumonisin B1 (HFB1) in corn by competitive direct enzyme-linked immunosorbent assay. | 1996 | Food Addit Contam | pmid:8647300 |
Canela R et al. | Fate of fumonisins B1 and B2 in steeped corn kernels. | 1996 | Food Addit Contam | pmid:8799714 |
Preis RA and Vargas EA | A method for determining fumonisin B1 in corn using immunoaffinity column clean-up and thin layer chromatography/densitometry. | 2000 | Food Addit Contam | pmid:10932789 |
Shim WB and Woloshuk CP | Nitrogen repression of fumonisin B1 biosynthesis in Gibberella fujikuroi. | 1999 | FEMS Microbiol. Lett. | pmid:10436928 |
Norholm MH et al. | Expression of the Arabidopsis high-affinity hexose transporter STP13 correlates with programmed cell death. | 2006 | FEBS Lett. | pmid:16616142 |
Xing F et al. | Reactive oxygen species promote chloroplast dysfunction and salicylic acid accumulation in fumonisin B1-induced cell death. | 2013 | FEBS Lett. | pmid:23711368 |
Kutuzov MA et al. | Expression and characterization of PP7, a novel plant protein Ser/Thr phosphatase distantly related to RdgC/PPEF and PP5. | 1998 | FEBS Lett. | pmid:9862444 |
Liu YY et al. | A role for ceramide in driving cancer cell resistance to doxorubicin. | 2008 | FASEB J. | pmid:18245173 |
Granata R et al. | Dual effects of IGFBP-3 on endothelial cell apoptosis and survival: involvement of the sphingolipid signaling pathways. | 2004 | FASEB J. | pmid:15247143 |
Bezombes C et al. | Lysosomal sphingomyelinase is not solicited for apoptosis signaling. | 2001 | FASEB J. | pmid:11156942 |
Zhao H et al. | Anoxia and reoxygenation of human endothelial cells decrease ceramide glucosyltransferase expression and activates caspases. | 2003 | FASEB J. | pmid:12586734 |
Stoev SD et al. | Experimental mycotoxic nephropathy in pigs provoked by a mouldy diet containing ochratoxin A and fumonisin B1. | 2012 | Exp. Toxicol. Pathol. | pmid:21296565 |
Lei M et al. | In vitro investigation of individual and combined cytotoxic effects of aflatoxin B1 and other selected mycotoxins on the cell line porcine kidney 15. | 2013 | Exp. Toxicol. Pathol. | pmid:23809186 |
Nadjia B and Fatima LD | Beneficial effects of Androctonus australis hector venom and its non-toxic fraction in the restoration of early hepatocyte-carcinogenesis induced by FB1 mycotoxin: Involvement of oxidative biomarkers. | 2015 | Exp. Mol. Pathol. | pmid:26142225 |
Itakura A et al. | Ceramide and sphingosine rapidly induce apoptosis of murine mast cells supported by interleukin-3 and stem cell factor. | 2002 | Exp. Hematol. | pmid:11882365 |
Isogai C et al. | Analysis of bax protein in sphingosine-induced apoptosis in the human leukemic cell line TF1 and its bcl-2 transfectants. | 1998 | Exp. Hematol. | pmid:9808050 |
Suzuki A et al. | Sequential operation of ceramide synthesis and ICE cascade in CPT-11-initiated apoptotic death signaling. | 1997 | Exp. Cell Res. | pmid:9184074 |