fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Itakura A et al. | Ceramide and sphingosine rapidly induce apoptosis of murine mast cells supported by interleukin-3 and stem cell factor. | 2002 | Exp. Hematol. | pmid:11882365 |
Theumer MG et al. | Immunobiological effects of fumonisin B1 in experimental subchronic mycotoxicoses in rats. | 2002 | Clin. Diagn. Lab. Immunol. | pmid:11777845 |
Mahfoud R et al. | pH-dependent interaction of fumonisin B1 with cholesterol: physicochemical and molecular modeling studies at the air-water interface. | 2002 | J. Agric. Food Chem. | pmid:11782202 |
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Howard PC et al. | Comparison of the toxicity of several fumonisin derivatives in a 28-day feeding study with female B6C3F(1) mice. | 2002 | Toxicol. Appl. Pharmacol. | pmid:12498732 |
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Banczerowski-Pelyhe I et al. | In vivo and in vitro electrophysiological monitoring of rat neocortical activity after dietary fumonisin exposure. | 2002 | Mycopathologia | pmid:11998878 |
Ehrlich V et al. | Fumonisin B(1) is genotoxic in human derived hepatoma (HepG2) cells. | 2002 | Mutagenesis | pmid:11971998 |
Enongene EN et al. | Persistence and reversibility of the elevation in free sphingoid bases induced by fumonisin inhibition of ceramide synthase. | 2002 | Toxicol. Sci. | pmid:12011476 |
Smith GW et al. | Cardiovascular changes associated with intravenous administration of fumonisin B1 in horses. | 2002 | Am. J. Vet. Res. | pmid:11939316 |
Seefelder W et al. | Analysis of fumonisin B(1) in Fusarium proliferatum-infected asparagus spears and garlic bulbs from Germany by liquid chromatography-electrospray ionization mass spectrometry. | 2002 | J. Agric. Food Chem. | pmid:11982398 |
Akao Y et al. | Ceramide accumulation is independent of camptothecin-induced apoptosis in prostate cancer LNCaP cells. | 2002 | Biochem. Biophys. Res. Commun. | pmid:12051721 |
Fotso J et al. | Production of beauvericin, moniliformin, fusaproliferin, and fumonisins b(1), b(2), and b(3) by fifteen ex-type strains of fusarium species. | 2002 | Appl. Environ. Microbiol. | pmid:12324376 |
Dresden-Osborne C and Noblet GP | Fumonisin B1 affects viability and alters nitric oxide production of a murine macrophage cell line. | 2002 | Int. Immunopharmacol. | pmid:12349946 |
Sadler TW et al. | Prevention of fumonisin B1-induced neural tube defects by folic acid. | 2002 | Teratology | pmid:12353213 |
Bhandari N et al. | Fumonisin B1-induced localized activation of cytokine network in mouse liver. | 2002 | Food Chem. Toxicol. | pmid:12387313 |
Desjardins AE et al. | FUM1--a gene required for fumonisin biosynthesis but not for maize ear rot and ear infection by Gibberella moniliformis in field tests. | 2002 | Mol. Plant Microbe Interact. | pmid:12423021 |
Cortez-Rocha MO et al. | Effect of extrusion processing on fumonisin B(1) and hydrolyzed fumonisin B(1) in contaminated alkali-cooked corn. | 2002 | Bull Environ Contam Toxicol | pmid:12232716 |
Le Stunff H et al. | Sphingosine-1-phosphate phosphohydrolase in regulation of sphingolipid metabolism and apoptosis. | 2002 | J. Cell Biol. | pmid:12235122 |
Camargos SM et al. | Accumulation of fumonisins B1 and B2 in freshly harvested Brazilian commercial maize at three locations during two nonconsecutive seasons. | 2002 | Mycopathologia | pmid:12650599 |
Min JK et al. | Simultaneous quantitative analysis of sphingoid base 1-phosphates in biological samples by o-phthalaldehyde precolumn derivatization after dephosphorylation with alkaline phosphatase. | 2002 | Anal. Biochem. | pmid:11950216 |
Gueguen G et al. | A lysophosphatidic acid analogue is revealed as a potent inhibitor of phosphatidylcholine synthesis, inducing apoptosis. | 2002 | Biochem. J. | pmid:12197836 |
Baron CL and Malhotra V | Role of diacylglycerol in PKD recruitment to the TGN and protein transport to the plasma membrane. | 2002 | Science | pmid:11729268 |
Galvano F et al. | DNA damage in human fibroblasts exposed to fumonisin B(1). | 2002 | Food Chem. Toxicol. | pmid:11731033 |
Bakan B et al. | Fungal growth and fusarium mycotoxin content in isogenic traditional maize and genetically modified maize grown in France and Spain. | 2002 | J. Agric. Food Chem. | pmid:11829636 |
Bird CB et al. | Determination of total fumonisins in corn by competitive direct enzyme-linked immunosorbent assay: collaborative study. | 2002 Mar-Apr | J AOAC Int | pmid:11990026 |
Velluti A et al. | Inhibitory effect of cinnamon, clove, lemongrass, oregano and palmarose essential oils on growth and fumonisin B1 production by Fusarium proliferatum in maize grain. | 2003 | Int. J. Food Microbiol. | pmid:14623380 |
Jiménez M et al. | Sugars and amino acids as factors affecting the synthesis of fumonisins in liquid cultures by isolates of the Gibberella fujikuroi complex. | 2003 | Int. J. Food Microbiol. | pmid:14623384 |
Okino N et al. | The reverse activity of human acid ceramidase. | 2003 | J. Biol. Chem. | pmid:12764132 |
Blomqvist M et al. | Selective lack of the C16:0 fatty acid isoform of sulfatide in pancreas of type II diabetic animal models. | 2003 | APMIS | pmid:14510644 |
Avantaggiato G et al. | Effects of muffin processing on fumonisins from 14C-labeled toxins produced in cultured corn kernels. | 2003 | J. Food Prot. | pmid:14572226 |
Sharma RP et al. | Increased expression of CD95-ligand and other apoptotic signaling factors by fumonisin B1, a hepatotoxic mycotoxin, in livers of mice lacking tumor necrosis factor alpha. | 2003 | Cytokine | pmid:14596819 |
Gopee NV et al. | Fumonisin B1-induced apoptosis is associated with delayed inhibition of protein kinase C, nuclear factor-kappaB and tumor necrosis factor alpha in LLC-PK1 cells. | 2003 | Chem. Biol. Interact. | pmid:14597127 |
Cirillo T et al. | Natural co-occurrence of deoxynivalenol and fumonisins B1 and B2 in Italian marketed foodstuffs. | 2003 | Food Addit Contam | pmid:12881130 |
Oswald IP et al. | Mycotoxin fumonisin B1 increases intestinal colonization by pathogenic Escherichia coli in pigs. | 2003 | Appl. Environ. Microbiol. | pmid:14532038 |
Sharma RP et al. | Deletion of IFN-gamma reduces fumonisin-induced hepatotoxicity in mice via alterations in inflammatory cytokines and apoptotic factors. | 2003 | J. Interferon Cytokine Res. | pmid:12639295 |
Litvak DA et al. | Modulators of ceramide metabolism sensitize colorectal cancer cells to chemotherapy: a novel treatment strategy. | 2003 | J. Gastrointest. Surg. | pmid:12559195 |
Suomalainen L et al. | Sphingosine-1-phosphate in inhibition of male germ cell apoptosis in the human testis. | 2003 | J. Clin. Endocrinol. Metab. | pmid:14602806 |
Tran ST et al. | Sphinganine to sphingosine ratio and predictive biochemical markers of fumonisin B1 exposure in ducks. | 2003 | Chem. Biol. Interact. | pmid:12902153 |
Maedler K et al. | Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function. | 2003 | Diabetes | pmid:12606514 |
Hinkovska-Galcheva V et al. | Enhanced phagocytosis through inhibition of de novo ceramide synthesis. | 2003 | J. Biol. Chem. | pmid:12424251 |
Cirillo T et al. | Evaluation of conventional and organic italian foodstuffs for deoxynivalenol and fumonisins B(1) and B(2). | 2003 | J. Agric. Food Chem. | pmid:14690407 |
Kim EK et al. | Hidden fumonisin in corn flakes. | 2003 | Food Addit Contam | pmid:12623665 |
Uchida Y et al. | De novo ceramide synthesis participates in the ultraviolet B irradiation-induced apoptosis in undifferentiated cultured human keratinocytes. | 2003 | J. Invest. Dermatol. | pmid:12648232 |
Beekrum S et al. | Naturally occurring phenols: a detoxification strategy for fumonisin B1. | 2003 | Food Addit Contam | pmid:12775468 |
El-Sayed AM et al. | Occurrence of certain mycotoxins in corn and corn-based products and thermostability of fumonisin B1 during processing. | 2003 | Nahrung | pmid:13678256 |
Gopee NV and Sharma RP | Sphingoid bases and their phosphates: transient activation and delayed repression of protein kinase C isoforms and their possible involvement in fumonisin B1 cytotoxicity. | 2003 | Toxicology | pmid:12699912 |
Kritzinger Q et al. | Mycoflora and fumonisin mycotoxins associated with cowpea [Vigna unguiculata (L.) Walp] seeds. | 2003 | J. Agric. Food Chem. | pmid:12670154 |
Koyanagi S et al. | Elevation of de novo ceramide synthesis in tumor masses and the role of microsomal dihydroceramide synthase. | 2003 | Int. J. Cancer | pmid:12672022 |
Johnson VJ et al. | Increased susceptibility of renal epithelial cells to TNFalpha-induced apoptosis following treatment with fumonisin B1. | 2003 | Chem. Biol. Interact. | pmid:12732456 |
Pepeljnjak S et al. | Screening toxicity study in young carp (Cyprinus carpio L.) on feed amended with fumonisin B1. | 2003 | Mycopathologia | pmid:12733635 |
Tornyos G et al. | Effect of dietary fumonisin B1 on certain immune parameters of weaned pigs. | 2003 | Acta Vet. Hung. | pmid:12737044 |
Hering H et al. | Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability. | 2003 | J. Neurosci. | pmid:12716933 |
Williams LD et al. | Leaching and binding of fumonisins in soil microcosms. | 2003 | J. Agric. Food Chem. | pmid:12537442 |
Zhao H et al. | Anoxia and reoxygenation of human endothelial cells decrease ceramide glucosyltransferase expression and activates caspases. | 2003 | FASEB J. | pmid:12586734 |
Leung LW et al. | Inhibitors of glycosphingolipid biosynthesis reduce transepithelial electrical resistance in MDCK I and FRT cells. | 2003 | Am. J. Physiol., Cell Physiol. | pmid:12490435 |
Ho JA and Durst RA | Detection of fumonisin B1: comparison of flow-injection liposome immunoanalysis with high-performance liquid chromatography. | 2003 | Anal. Biochem. | pmid:12479829 |
Mobio TA et al. | Comparative study of the toxic effects of fumonisin B1 in rat C6 glioma cells and p53-null mouse embryo fibroblasts. | 2003 | Toxicology | pmid:12504343 |
Seefelder W et al. | Bound fumonisin B1: analysis of fumonisin-B1 glyco and amino acid conjugates by liquid chromatography-electrospray ionization-tandem mass spectrometry. | 2003 | J. Agric. Food Chem. | pmid:12926916 |
van der Westhuizen L et al. | Fumonisin contamination and fusarium incidence in corn from Santa Catarina, Brazil. | 2003 | J. Agric. Food Chem. | pmid:12926917 |
Riebeling C et al. | Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors. | 2003 | J. Biol. Chem. | pmid:12912983 |
Meyer K et al. | Residue formation of fumonisin B1 in porcine tissues. | 2003 | Food Addit Contam | pmid:12888389 |
Palencia E et al. | Total fumonisins are reduced in tortillas using the traditional nixtamalization method of mayan communities. | 2003 | J. Nutr. | pmid:14519811 |
Theumer MG et al. | Immunobiological effects of AFB1 and AFB1-FB1 mixture in experimental subchronic mycotoxicoses in rats. | 2003 | Toxicology | pmid:12604180 |
Dilkin P et al. | Toxicological effects of chronic low doses of aflatoxin B(1) and fumonisin B(1)-containing Fusarium moniliforme culture material in weaned piglets. | 2003 | Food Chem. Toxicol. | pmid:12909268 |
Shim WB et al. | Comparison of fumonisin B1 biosynthesis in maize germ and degermed kernels by Fusarium verticillioides. | 2003 | J. Food Prot. | pmid:14627291 |
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Ledoux DR et al. | Individual and combined effects of the Fusarium mycotoxins fumonisin B1 and moniliformin in broiler chicks. | 2003 Oct-Dec | Avian Dis. | pmid:14708984 |
Cavaglieri L et al. | Screening procedures for selecting rhizobacteria with biocontrol effects upon Fusarium verticillioides growth and fumonisin B1 production. | 2004 | Res. Microbiol. | pmid:15501652 |
Petrinec Z et al. | Fumonisin B1 causes multiple lesions in common carp (Cyprinus carpio). | 2004 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:15503536 |
Lang KS et al. | Involvement of ceramide in hyperosmotic shock-induced death of erythrocytes. | 2004 | Cell Death Differ. | pmid:14615798 |
Bouhet S et al. | The mycotoxin fumonisin B1 alters the proliferation and the barrier function of porcine intestinal epithelial cells. | 2004 | Toxicol. Sci. | pmid:14600282 |
Blázquez C et al. | Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas. | 2004 | Cancer Res. | pmid:15313899 |
Worgall TS et al. | Ceramide synthesis correlates with the posttranscriptional regulation of the sterol-regulatory element-binding protein. | 2004 | Arterioscler. Thromb. Vasc. Biol. | pmid:15132973 |
Aly SE et al. | Application of adsorbent agents technology in the removal of aflatoxin B(1) and fumonisin B(1) from malt extract. | 2004 | Food Chem. Toxicol. | pmid:15350680 |
Tardieu D et al. | Toxicity of maize containing known levels of fumonisin B1 during force-feeding of ducks. | 2004 | Poult. Sci. | pmid:15339002 |
Van IJzendoorn SC et al. | Polarized membrane traffic and cell polarity development is dependent on dihydroceramide synthase-regulated sphinganine turnover. | 2004 | Mol. Biol. Cell | pmid:15229289 |
van der Westhuizen L et al. | Disruption of sphingolipid biosynthesis in hepatocyte nodules: selective proliferative stimulus induced by fumonisin B1. | 2004 | Toxicology | pmid:15158565 |
Royer D et al. | Quantitative analysis of Fusarium mycotoxins in maize using accelerated solvent extraction before liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry. | 2004 | Food Addit Contam | pmid:15370841 |
Sharma N et al. | Sphingosine kinase activity confers resistance to apoptosis by fumonisin B1 in human embryonic kidney (HEK-293) cells. | 2004 | Chem. Biol. Interact. | pmid:15607760 |
Ogido R et al. | Effects of prolonged administration of aflatoxin B1 and fumonisin B1 in laying Japanese quail. | 2004 | Poult. Sci. | pmid:15615006 |
Fortin DL et al. | Lipid rafts mediate the synaptic localization of alpha-synuclein. | 2004 | J. Neurosci. | pmid:15282274 |
Vismer HF et al. | Production of fumonisins by Fusarium verticillioides strains on solid and in a defined liquid medium--effects of L-methionine and inoculum. | 2004 | Mycopathologia | pmid:15487327 |
Gopee NV and Sharma RP | The mycotoxin fumonisin B1 transiently activates nuclear factor-kappaB, tumor necrosis factor alpha and caspase 3 via protein kinase Calpha-dependent pathway in porcine renal epithelial cells. | 2004 | Cell Biol. Toxicol. | pmid:15499968 |