fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Adenocarcinoma D000230 166 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Inflammation D007249 119 associated lipids
Glioma D005910 112 associated lipids
Weight Gain D015430 101 associated lipids
Seizures D012640 87 associated lipids
Stomach Ulcer D013276 75 associated lipids
Neuroblastoma D009447 66 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Asthma D001249 52 associated lipids
Precancerous Conditions D011230 48 associated lipids
Fatty Liver D005234 48 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Adenoma D000236 40 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Lung Diseases D008171 37 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

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Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
Yi F et al. Homocysteine activates NADH/NADPH oxidase through ceramide-stimulated Rac GTPase activity in rat mesangial cells. 2004 Kidney Int. pmid:15496169
Gopee NV and Sharma RP The mycotoxin fumonisin B1 transiently activates nuclear factor-kappaB, tumor necrosis factor alpha and caspase 3 via protein kinase Calpha-dependent pathway in porcine renal epithelial cells. 2004 Cell Biol. Toxicol. pmid:15499968
Cavaglieri L et al. Screening procedures for selecting rhizobacteria with biocontrol effects upon Fusarium verticillioides growth and fumonisin B1 production. 2004 Res. Microbiol. pmid:15501652
Petrinec Z et al. Fumonisin B1 causes multiple lesions in common carp (Cyprinus carpio). 2004 DTW. Dtsch. Tierarztl. Wochenschr. pmid:15503536
Yu MU et al. Altered de novo sphingolipid biosynthesis is involved in the serum deprivation-induced cell death in LLC-PK1 cells. 2004 J. Toxicol. Environ. Health Part A pmid:15513905
Becker KP et al. Selective inhibition of juxtanuclear translocation of protein kinase C betaII by a negative feedback mechanism involving ceramide formed from the salvage pathway. 2005 J. Biol. Chem. pmid:15546881
Osweiler GD et al. Characterization of an epizootic of pulmonary edema in swine associated with fumonisin in corn screenings. 1992 J. Vet. Diagn. Invest. pmid:1554770
Rentz SS et al. Inhibition of sphingolipid biosynthesis decreases phosphorylated ERK2 in LLC-PK1 cells. 2005 Food Chem. Toxicol. pmid:15582204
De Liguoro M et al. Field observations in pigs exposed to fumonisin B1 contaminated feed. 2004 Vet Hum Toxicol pmid:15587243
He Q et al. Fumonisin B1 hepatotoxicity in mice is attenuated by depletion of Kupffer cells by gadolinium chloride. 2005 Toxicology pmid:15590129
Sharma N et al. Sphingosine kinase activity confers resistance to apoptosis by fumonisin B1 in human embryonic kidney (HEK-293) cells. 2004 Chem. Biol. Interact. pmid:15607760
Hinojo MJ et al. Utility of the polymerase chain reaction-restriction fragment length polymorphisms of the intergenic spacer region of the rDNA for characterizing Gibberella fujikuroi isolates. 2004 Syst. Appl. Microbiol. pmid:15612625
Ogido R et al. Effects of prolonged administration of aflatoxin B1 and fumonisin B1 in laying Japanese quail. 2004 Poult. Sci. pmid:15615006
Stockmann-Juvala H et al. Oxidative stress induced by fumonisin B1 in continuous human and rodent neural cell cultures. 2004 Free Radic. Res. pmid:15621711
Ono EY et al. Trends of fumonisin contamination and animal intoxication through monitoring 1991 to 1997 corn crop in the State of Paraná, Brazil. 2004 Mycopathologia pmid:15630554
Taranu I et al. Mycotoxin fumonisin B1 alters the cytokine profile and decreases the vaccinal antibody titer in pigs. 2005 Toxicol. Sci. pmid:15659571
Cabrera RM et al. Investigations into the etiology of neural tube defects. 2004 Birth Defects Res. C Embryo Today pmid:15662706
Nikièma PN et al. Fumonisin contamination of maize in Burkina Faso, West Africa. 2004 Food Addit Contam pmid:15666980
Fernández-Surumay G et al. Glucose reaction with fumonisin B1 partially reduces its toxicity in swine. 2004 J. Agric. Food Chem. pmid:15675827
Suga K et al. [Analysis of fumonisin B1 and B2 in beer and raw materials of beer by liquid chromatography/tandem mass spectrometry]. 2004 Shokuhin Eiseigaku Zasshi pmid:15678940