fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Asthma D001249 52 associated lipids
Body Weight D001835 333 associated lipids
Brain Diseases D001927 27 associated lipids
Carcinoma D002277 18 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Choline Deficiency D002796 16 associated lipids
Cleft Palate D002972 9 associated lipids
Death, Sudden D003645 12 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Fatty Liver D005234 48 associated lipids
Fetal Resorption D005327 15 associated lipids
Gaucher Disease D005776 13 associated lipids
Glioblastoma D005909 27 associated lipids
Glioma D005910 112 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hydrocephalus D006849 6 associated lipids
Hyperplasia D006965 34 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

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Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
Gelderblom WC et al. Interaction of fumonisin B(1) and aflatoxin B(1) in a short-term carcinogenesis model in rat liver. 2002 Toxicology pmid:11836022
Bhandari N and Sharma RP Fumonisin B(1)-induced alterations in cytokine expression and apoptosis signaling genes in mouse liver and kidney after an acute exposure. 2002 Toxicology pmid:11882348
Sharma N et al. Augmented fumonisin B1 toxicity in co-cultures: evidence for crosstalk between macrophages and non-parenchymatous liver epithelial cells involving proinflammatory cytokines. 2004 Toxicology pmid:15363598
Stockmann-Juvala H et al. Fumonisin B1-induced toxicity and oxidative damage in U-118MG glioblastoma cells. 2004 Toxicology pmid:15337581
Creppy EE et al. Synergistic effects of fumonisin B1 and ochratoxin A: are in vitro cytotoxicity data predictive of in vivo acute toxicity? 2004 Toxicology pmid:15297026
Gelderblom WC et al. Toxicological effects in rats chronically fed low dietary levels of fumonisin B(1). 2001 Toxicology pmid:11295254
Theumer MG et al. Subchronic mycotoxicoses in Wistar rats: assessment of the in vivo and in vitro genotoxicity induced by fumonisins and aflatoxin B(1), and oxidative stress biomarkers status. 2010 Toxicology pmid:20015463
Sharma N et al. Amelioration of fumonisin B1 hepatotoxicity in mice by depletion of T cells with anti-Thy-1.2. 2006 Toxicology pmid:16690192
van der Westhuizen L et al. Disruption of sphingolipid biosynthesis in hepatocyte nodules: selective proliferative stimulus induced by fumonisin B1. 2004 Toxicology pmid:15158565
Gelderblom WC et al. Cancer initiating properties of fumonisin B1 in a short-term rat liver carcinogenesis assay. 2008 Toxicology pmid:18616970
Mobio TA et al. Comparative study of the toxic effects of fumonisin B1 in rat C6 glioma cells and p53-null mouse embryo fibroblasts. 2003 Toxicology pmid:12504343
Domijan AM et al. Fumonisin B(1): oxidative status and DNA damage in rats. 2007 Toxicology pmid:17291664
Rumora L et al. Mycotoxin fumonisin B1 alters cellular redox balance and signalling pathways in rat liver and kidney. 2007 Toxicology pmid:17949882
Sharma RP et al. Tolerance to fumonisin toxicity in a mouse strain lacking the P75 tumor necrosis factor receptor. 2000 Toxicology pmid:10755704
Biswal SS et al. Changes in ceramide and sphingomyelin following fludarabine treatment of human chronic B-cell leukemia cells. 2000 Toxicology pmid:11118669
He Q et al. Fumonisin B1 hepatotoxicity in mice is attenuated by depletion of Kupffer cells by gadolinium chloride. 2005 Toxicology pmid:15590129
Gumprecht LA et al. Species and organ specificity of fumonisin-induced endothelial alterations: potential role in porcine pulmonary edema. 2001 Toxicology pmid:11246126
Sharma RP et al. Decreased fumonisin hepatotoxicity in mice with a targeted deletion of tumor necrosis factor receptor 1. 2001 Toxicology pmid:11250056
Bhandari N et al. Gender-related differences in subacute fumonisin B1 hepatotoxicity in BALB/c mice. 2001 Toxicology pmid:11522378
Mary VS et al. Reactive oxygen species sources and biomolecular oxidative damage induced by aflatoxin B1 and fumonisin B1 in rat spleen mononuclear cells. 2012 Toxicology pmid:22981896