| MeSH term | MeSH ID | Detail |
|---|---|---|
| Chemical and Drug Induced Liver Injury | D056486 | 39 associated lipids |
| Pneumonia, Bacterial | D018410 | 16 associated lipids |
| Adenoma, Liver Cell | D018248 | 2 associated lipids |
| Neuroectodermal Tumors, Primitive, Peripheral | D018241 | 3 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Testicular Diseases | D013733 | 15 associated lipids |
| Swine Diseases | D013553 | 16 associated lipids |
| Stomatitis | D013280 | 14 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Spinal Cord Injuries | D013119 | 34 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Scrapie | D012608 | 7 associated lipids |
| Salmonella Infections, Animal | D012481 | 9 associated lipids |
| Pulmonary Edema | D011654 | 23 associated lipids |
| Pseudorabies | D011557 | 1 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Poultry Diseases | D011201 | 21 associated lipids |
| Pasteurella Infections | D010326 | 8 associated lipids |
| Paralysis | D010243 | 4 associated lipids |
fumonisin b1
fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
Cross Reference
Introduction
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with fumonisin b1?
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Am. J. Physiol. Heart Circ. Physiol. (1)
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Cancer Res. (1)
- Others (5)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with fumonisin b1
PubChem Associated disorders and diseases
What pathways are associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with fumonisin b1?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with fumonisin b1?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with fumonisin b1?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with fumonisin b1?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with fumonisin b1?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with fumonisin b1
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| El Bawab S et al. | Biochemical characterization of the reverse activity of rat brain ceramidase. A CoA-independent and fumonisin B1-insensitive ceramide synthase. | 2001 | J. Biol. Chem. | pmid:11278489 |
| Kuroyanagi M et al. | Vacuolar processing enzyme is essential for mycotoxin-induced cell death in Arabidopsis thaliana. | 2005 | J. Biol. Chem. | pmid:16043487 |
| Chalfant CE et al. | De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1. | 2002 | J. Biol. Chem. | pmid:11801602 |
| Le Stunff H et al. | Role of sphingosine-1-phosphate phosphatase 1 in epidermal growth factor-induced chemotaxis. | 2004 | J. Biol. Chem. | pmid:15180992 |
| Kroesen BJ et al. | Induction of apoptosis through B-cell receptor cross-linking occurs via de novo generated C16-ceramide and involves mitochondria. | 2001 | J. Biol. Chem. | pmid:11278517 |
| Stevens VL and Tang J | Fumonisin B1-induced sphingolipid depletion inhibits vitamin uptake via the glycosylphosphatidylinositol-anchored folate receptor. | 1997 | J. Biol. Chem. | pmid:9218430 |
| Mullen TD et al. | Ceramide synthase-dependent ceramide generation and programmed cell death: involvement of salvage pathway in regulating postmitochondrial events. | 2011 | J. Biol. Chem. | pmid:21388949 |
| Jenkins GM et al. | Acute activation of de novo sphingolipid biosynthesis upon heat shock causes an accumulation of ceramide and subsequent dephosphorylation of SR proteins. | 2002 | J. Biol. Chem. | pmid:12200446 |
| Wiesner DA et al. | Anti-immunoglobulin-induced apoptosis in WEHI 231 cells involves the slow formation of ceramide from sphingomyelin and is blocked by bcl-XL. | 1997 | J. Biol. Chem. | pmid:9092523 |
| Wang E et al. | Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme. | 1991 | J. Biol. Chem. | pmid:1860857 |
| Zitomer NC et al. | Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals. | 2009 | J. Biol. Chem. | pmid:19095642 |
| Hinkovska-Galcheva V et al. | Enhanced phagocytosis through inhibition of de novo ceramide synthesis. | 2003 | J. Biol. Chem. | pmid:12424251 |
| Wieder T et al. | Induction of ceramide-mediated apoptosis by the anticancer phospholipid analog, hexadecylphosphocholine. | 1998 | J. Biol. Chem. | pmid:9556584 |
| Sofer A and Futerman AH | Cationic amphiphilic drugs inhibit the internalization of cholera toxin to the Golgi apparatus and the subsequent elevation of cyclic AMP. | 1995 | J. Biol. Chem. | pmid:7744860 |
| Jarvis WD et al. | Induction of apoptosis and potentiation of ceramide-mediated cytotoxicity by sphingoid bases in human myeloid leukemia cells. | 1996 | J. Biol. Chem. | pmid:8626522 |
| Penno A et al. | Hereditary sensory neuropathy type 1 is caused by the accumulation of two neurotoxic sphingolipids. | 2010 | J. Biol. Chem. | pmid:20097765 |
| Riebeling C et al. | Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors. | 2003 | J. Biol. Chem. | pmid:12912983 |
| Harel R and Futerman AH | Inhibition of sphingolipid synthesis affects axonal outgrowth in cultured hippocampal neurons. | 1993 | J. Biol. Chem. | pmid:8314804 |
| Zhang Y et al. | The mycotoxin fumonisin B1 transcriptionally activates the p21 promoter through a cis-acting element containing two Sp1 binding sites. | 1999 | J. Biol. Chem. | pmid:10212208 |
| Kitatani K et al. | Mechanism of inhibition of sequestration of protein kinase C alpha/betaII by ceramide. Roles of ceramide-activated protein phosphatases and phosphorylation/dephosphorylation of protein kinase C alpha/betaII on threonine 638/641. | 2007 | J. Biol. Chem. | pmid:17504762 |
| Williamson LC et al. | Neuronal sensitivity to tetanus toxin requires gangliosides. | 1999 | J. Biol. Chem. | pmid:10455200 |
| Becker KP et al. | Selective inhibition of juxtanuclear translocation of protein kinase C betaII by a negative feedback mechanism involving ceramide formed from the salvage pathway. | 2005 | J. Biol. Chem. | pmid:15546881 |
| Balsinde J et al. | Inflammatory activation of arachidonic acid signaling in murine P388D1 macrophages via sphingomyelin synthesis. | 1997 | J. Biol. Chem. | pmid:9252342 |
| Cuvillier O et al. | Involvement of sphingosine in mitochondria-dependent Fas-induced apoptosis of type II Jurkat T cells. | 2000 | J. Biol. Chem. | pmid:10747891 |
| Mao C et al. | Cloning of an alkaline ceramidase from Saccharomyces cerevisiae. An enzyme with reverse (CoA-independent) ceramide synthase activity. | 2000 | J. Biol. Chem. | pmid:10702247 |
| Hernández-Corbacho MJ et al. | Tumor Necrosis Factor-α (TNFα)-induced Ceramide Generation via Ceramide Synthases Regulates Loss of Focal Adhesion Kinase (FAK) and Programmed Cell Death. | 2015 | J. Biol. Chem. | pmid:26318452 |
| Kang YJ and Alexander JM | Alterations of the glutathione redox cycle status in fumonisin B1-treated pig kidney cells. | 1996 | J. Biochem. Toxicol. | pmid:9029270 |
| Sharma N et al. | Tumor necrosis factor alpha-mediated activation of c-Jun NH(2)-terminal kinase as a mechanism for fumonisin B(1) induced apoptosis in murine primary hepatocytes. | 2005 | J. Biochem. Mol. Toxicol. | pmid:16421893 |
| Jenkins GR et al. | Identification of fumonisin B1 as an inhibitor of argininosuccinate synthetase using fumonisin affinity chromatography and in vitro kinetic studies. | 2000 | J. Biochem. Mol. Toxicol. | pmid:11083085 |
| Tsunoda M et al. | Early fumonisin B1 toxicity in relation to disrupted sphingolipid metabolism in male BALB/c mice. | 1998 | J. Biochem. Mol. Toxicol. | pmid:9664234 |
| Boeira LS et al. | The effect of combinations of Fusarium mycotoxins (deoxynivalenol, zearalenone and fumonisin B1) on growth of brewing yeasts. | 2000 | J. Appl. Microbiol. | pmid:10747219 |
| Niderkorn V et al. | Cell wall component and mycotoxin moieties involved in the binding of fumonisin B1 and B2 by lactic acid bacteria. | 2009 | J. Appl. Microbiol. | pmid:19187153 |
| Armando MR et al. | Statistical optimization of culture conditions for biomass production of probiotic gut-borne Saccharomyces cerevisiae strain able to reduce fumonisin B1. | 2013 | J. Appl. Microbiol. | pmid:23347149 |
| Dawidziuk A et al. | Molecular diagnostics on the toxigenic potential of Fusarium spp. plant pathogens. | 2014 | J. Appl. Microbiol. | pmid:24575830 |
| Irzykowska L et al. | Genetic variation of Fusarium oxysporum isolates forming fumonisin B(1) and moniliformin. | 2012 | J. Appl. Genet. | pmid:22367665 |
| Edrington TS et al. | Acute hepatic and renal toxicity in lambs dosed with fumonisin-containing culture material. | 1995 | J. Anim. Sci. | pmid:7601785 |
| Piva A et al. | Activated carbon does not prevent the toxicity of culture material containing fumonisin B1 when fed to weanling piglets. | 2005 | J. Anim. Sci. | pmid:16024715 |
| Delgado JE and Wolt JD | Fumonisin B(1) and implications in nursery swine productivity: a quantitative exposure assessment. | 2010 | J. Anim. Sci. | pmid:20622179 |
| Gurung NK et al. | Effects of fumonisin B1-contaminated feeds on weanling angora goats. | 1998 | J. Anim. Sci. | pmid:9856397 |
| Price WD et al. | Naturally occurring toxins in feedstuffs: Center for Veterinary Medicine Perspective. | 1993 | J. Anim. Sci. | pmid:8407668 |
| Wilson TM et al. | Fumonisin mycotoxins and equine leukoencephalomalacia. | 1991 | J. Am. Vet. Med. Assoc. | pmid:2045319 |
| Ueda N et al. | Role of ceramide synthase in oxidant injury to renal tubular epithelial cells. | 2001 | J. Am. Soc. Nephrol. | pmid:11675414 |
| Pereira CL et al. | Total synthesis of the sphingolipid biosynthesis inhibitor fumonisin B(1). | 2009 | J. Am. Chem. Soc. | pmid:19354245 |
| Li C et al. | Development of a screening fluorescence polarization immunoassay for the simultaneous detection of fumonisins Bâ‚ and Bâ‚‚ in maize. | 2015 | J. Agric. Food Chem. | pmid:25942573 |
| Sewram V et al. | Mycotoxin contamination of dietary and medicinal wild plants in the Eastern Cape Province of South Africa. | 2006 | J. Agric. Food Chem. | pmid:16848564 |
| Kritzinger Q et al. | Mycoflora and fumonisin mycotoxins associated with cowpea [Vigna unguiculata (L.) Walp] seeds. | 2003 | J. Agric. Food Chem. | pmid:12670154 |
| Shephard GS et al. | Natural occurrence of fumonisins in corn from Iran. | 2000 | J. Agric. Food Chem. | pmid:10820105 |
| Baldwin TT et al. | Maize seedling blight induced by Fusarium verticillioides: accumulation of fumonisin Bâ‚ in leaves without colonization of the leaves. | 2014 | J. Agric. Food Chem. | pmid:24524621 |
| Dombrink-Kurtzman MA et al. | Effect of nixtamalization (Alkaline cooking) on fumonisin-contaminated corn for production of masa and tortillas. | 2000 | J. Agric. Food Chem. | pmid:11087554 |
| Yuan CW et al. | Evaluation of Efficacy and Toxicity of Exfoliated Silicate Nanoclays as a Feed Additive for Fumonisin Detoxification. | 2017 | J. Agric. Food Chem. | pmid:28712299 |